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11. 发明申请

US20050043304A1 Novel amine derivative having human beta-tryptase inhibitory activity and drugs containing the same 审中-公开
标题翻译：具有人β-胰蛋白酶抑制活性的新型胺衍生物和含有它们的药物
公开(公告)号：US20050043304A1
公开(公告)日：2005-02-24
申请号：US10485331
申请日：2002-08-01
申请人： Yutaka Kato , Yutaka Miyazaki , Hiroyasu Shimada , Tadashi Manabe , Ikuya Shiromizu , Atsushi Okamoto
发明人： Yutaka Kato , Yutaka Miyazaki , Hiroyasu Shimada , Tadashi Manabe , Ikuya Shiromizu , Atsushi Okamoto
IPC分类号： A61K31/137 , A61K31/166 , A61K31/18 , A61K31/381 , A61K31/428 , A61K31/47 , A61K31/472 , A61P1/00 , A61P9/00 , A61P11/00 , A61P11/06 , A61P17/00 , A61P27/14 , A61P27/16 , A61P29/00 , A61P37/08 , A61P43/00 , C07C233/78 , C07C311/18 , C07D209/08 , C07D209/20 , C07D215/48 , C07D217/02 , C07D235/08 , C07D307/82 , C07D307/85 , C07D317/62 , C07D333/62 , C07D401/12 , C07D409/12 , C07D251/48 , A61K31/497 , A61K31/53 , C07D237/02
CPC分类号： C07D307/82 , A61K31/137 , A61K31/166 , A61K31/18 , A61K31/381 , A61K31/428 , A61K31/47 , A61K31/472 , C07C233/78 , C07C311/18 , C07C2602/08 , C07D209/08 , C07D209/20 , C07D215/48 , C07D217/02 , C07D235/08 , C07D307/85 , C07D317/62 , C07D333/62 , C07D401/12 , C07D409/12
摘要： It is intended to provide a novel low-molecular weight amine derivative, that is absorbed well, has low toxicity, and has an excellent human β-tryptase inhibitory activity with extremely high selectivity, a pharmaceutically acceptable salt thereof, and a medicine containing the same as an active ingredient. The medicine of the present invention is efficacious as a prophylactic/therapeutic agent for diseases in the crisis and evolution of which are considered to be attributed to β-tryptase, for example, respiratory diseases, allergic diseases, inflammatory bowel diseases, hyperprolliferative skin diseases, vascular edema and rheumatoid arthritis.
摘要翻译：旨在提供一种新颖的低分子量胺衍生物，其被良好吸收，具有低毒性，并且具有极高选择性的优异的人β-类胰蛋白酶抑制活性，其药学上可接受的盐和含有它们的药物作为活性成分。本发明的药物作为危机中的疾病的预防/治疗剂是有效的，其进化被认为归因于β-类胰蛋白酶，例如呼吸系统疾病，过敏性疾病，炎性肠病，过度增生性皮肤病，血管性水肿和类风湿性关节炎。

12. 发明授权

US06379552B1 Method for resolving optical isomers 失效
标题翻译：拆分光学异构体的方法
公开(公告)号：US06379552B1
公开(公告)日：2002-04-30
申请号：US09347062
申请日：1999-07-02
申请人： Tetsuji Kitagawa , Atsushi Okamoto , Takashi Kanai , Katsuhiro Shibayama , Tomoyuki Aoki , Shinobu Yamakawa
发明人： Tetsuji Kitagawa , Atsushi Okamoto , Takashi Kanai , Katsuhiro Shibayama , Tomoyuki Aoki , Shinobu Yamakawa
IPC分类号： B01D1500
CPC分类号： C07B57/00
摘要： A method for efficiently resolving optical isomers, in which a discriminating liquid consisting of a discriminating agent capable of discriminating optical isomers and a diluent are brought into contact with a mixture containing said optical isomers in countercurrent flow, to resolve the optical isomers by adsorption separation, distillation separation, absorption separation or membrane separation, and recovered at an optical isomer content of 5 wt % or less for recycled use, under one or more of the following conditions: (a) the dielectric constant of the diluent is 30 or less and the viscosity of the discriminating liquid is 0.2 Pa·s or less at the temperature of the resolving operation; (b) the discriminating agent contained has the effect of splitting the 1H or 13C-NMR spectrum peak of the optical isomers when added and the diluent contained has a dielectric constant equal to or lower than the dielectric constant of the measuring solvent at the time of measuring the 1H or 13C-NMR spectrum; (c) the boiling point of at least one compound of the discriminating agent at the pressure of the resolving operation is higher than the boiling point of at least one compound of the diluent at the pressure of the resolving operation; (d) the boiling point of at least one compound of the diluent at the pressure of the resolving operation is higher than the boiling point of the optical isomers to be resolved, at the pressure of the resolving operation, by 10° C. or more; and (e) the concentration of the discriminating agent in the discriminating liquid is 10 wt % or more.
摘要翻译：光学异构体的有效解决方法是将由能够鉴别光学异构体的识别剂组成的识别液与稀释剂逆流流动地与包含所述光学异构体的混合物接触，从而通过吸附分离来分解光学异构体，蒸馏分离，吸收分离或膜分离，并在一种或多种以下条件下以5重量％以下的光学异构体含量回收再循环使用：（a）稀释剂的介电常数为30以下，鉴定液的粘度在分解操作的温度下为0.2Pa.s以下;（b）所含的鉴别剂具有在添加时分解光学异构体的1H或13C-NMR谱峰的作用，并且稀释剂含有介电常数等于或低于在测量1H或13C-NMR谱时测量溶剂的介电常数（c）解析操作压力下鉴别剂的至少一种化合物的沸点高于分解操作压力下至少一种稀释剂化合物的沸点;（d）在拆分操作压力下，至少一种稀释剂化合物的沸点高于分解操作压力下要拆分的光学异构体的沸点10℃或更高; 和（e）鉴别液中鉴别剂的浓度为10重量％以上。

13. 发明授权

US06342944B1 Vertical alignment table mechanism 失效
标题翻译：垂直对齐表机构
公开(公告)号：US06342944B1
公开(公告)日：2002-01-29
申请号：US09510757
申请日：2000-02-22
申请人： Atsushi Okamoto
发明人： Atsushi Okamoto
IPC分类号： G03B2762
CPC分类号： G03B27/62
摘要： A vertical alignment table mechanism 21 for a board 25 to form a printed wiring board has a vertical support wall 43, and an alignment table 33 disposed in vertical attitude opposite to the front surface of the support wall 43, having an opening in which an exposure mask 23 is disposed. The alignment table 33 is supported for movement in a vertical plane on the vertical support wall 43 by a means of plurality of table support devices 35. Each of the table support devices 35 includes a ball caster 51 fixed to the support wall 43 having a ball 51a therein and a contact block 53 fixed to the alignment table 33. A tension spring 55 urges the surface of the contact block 53 against the ball. Table moving devices 37 are also provided between the support wall 43 and the alignment table 33. Each table moving device 37 includes a contact block 85 on the alignment table, and a follower roller 83 on the support wall 43. A spring 37 urges the follower roller 83 against the contact block 85. A pulse motor 71 causes movement of the alignment table 33 relative to the support wall 35.
摘要翻译：用于形成印刷电路板的板25的垂直对准台机构21具有垂直支撑壁43和与支撑壁43的前表面相对的垂直姿态设置的对准台33，其具有开口，曝光设置掩模23。对准台33被支撑用于通过多个台面支撑装置35在垂直支撑壁43上的垂直平面中运动。桌子支撑装置35中的每一个包括固定到具有球的支撑壁43的球形脚轮51 51a和固定到对准台33的接触块53.拉伸弹簧55将接触块53的表面推向球。桌子移动装置37也设置在支撑壁43和对准台33之间。每个桌子移动装置37包括对准台上的接触块85和支撑壁43上的从动辊83.弹簧37推动跟随器辊83抵靠接触块85.脉冲电动机71引起对准台33相对于支撑壁35的移动。

14. 发明授权

US06211942B1 Double-sided exposure system 失效
标题翻译：双面曝光系统
公开(公告)号：US06211942B1
公开(公告)日：2001-04-03
申请号：US09523326
申请日：2000-03-10
申请人： Atsushi Okamoto
发明人： Atsushi Okamoto
IPC分类号： G03B2732
CPC分类号： G03F7/70425 , G03F7/203 , H05K3/0082
摘要： A double-sided exposure system (1) has a first work holding device (21L) for holding a substrate (P) opposite to an exposure mask (55) to expose a first surface of the substrate (P) through the exposure mask (55) to light, and a second work holding device (21R) for holding the substrate (P) opposite to another exposure mask (55) to exposure a second surface of the substrate (P) through the exposure mask (55) to light. Phases of operations for receiving, transferring and pretreating an unexposed substrate, and those of operations for transferring, exposing and pretreating the substrate having one surface processed by an exposure operation can be staggered to prevent time loss due to waiting during an exposure operation can be prevented even if the double-sided exposure system is provided with a single light source.
摘要翻译：双面曝光系统（1）具有用于保持与曝光掩模（55）相对的基板（P）的第一工件保持装置（21L），以通过曝光掩模（55）暴露基板（P）的第一表面）和用于保持与另一个曝光掩模（55）相对的基板（P）的第二工件保持装置（21R），以通过曝光掩模（55）将基板（P）的第二表面曝光。用于接收，转印和处理未曝光的基板的操作阶段以及用于转印，曝光和预处理具有通过曝光操作处理的一个表面的基板的操作的操作可以错开以防止由于在曝光操作期间的等待而引起的时间损失即使双面曝光系统设置有单个光源。

15. 发明授权

US09316423B2 Container refrigeration apparatus 有权
标题翻译：集装箱制冷装置
公开(公告)号：US09316423B2
公开(公告)日：2016-04-19
申请号：US13511874
申请日：2010-10-22
申请人： Kazuma Yokohara , Yuusuke Fujimoto , Atsushi Okamoto
发明人： Kazuma Yokohara , Yuusuke Fujimoto , Atsushi Okamoto
IPC分类号： F25B29/00 , F25B41/04 , F25D11/00 , F25D31/00
CPC分类号： F25B41/04 , F25B2400/0403 , F25B2400/13 , F25B2400/19 , F25B2600/0253 , F25B2600/2507 , F25B2700/1931 , F25B2700/1933 , F25B2700/2103 , F25B2700/2106 , F25B2700/21151 , F25B2700/21152 , F25B2700/21172 , F25B2700/21173 , F25B2700/21174 , F25B2700/21175 , F25D11/003 , F25D31/005 , Y02B30/741 , Y02B40/32
摘要： A container refrigeration apparatus includes: a refrigerant circuit which performs a refrigeration cycle, and includes a main circuit sequentially connecting a compressor, a condenser, a main expansion valve and an evaporator, and a hot gas bypass circuit through which a refrigerant compressed in the compressor bypasses the condenser and the main expansion valve to flow into the evaporator; and a compressor control section which controls operating speed of rotation of the compressor during heating operation for heating inside of a container by the evaporator while returning the compressed refrigerant from the compressor to the compressor through the hot gas bypass circuit and the evaporator so that a temperature inside the container reaches a target temperature.
摘要翻译：一种容器制冷装置，具备：制冷剂循环的制冷剂回路，包括顺序地连接压缩机，冷凝器，主膨胀阀和蒸发器的主回路，以及在压缩机中压缩的制冷剂的热气旁通回路绕过冷凝器和主膨胀阀流入蒸发器; 以及压缩机控制部，其通过蒸发器控制在加热运转中的加热运转中的压缩机的旋转速度，同时通过热气旁路回路和蒸发器将压缩的制冷剂从压缩机返回到压缩机，使得温度容器内部达到目标温度。

16. 发明授权

US08899056B2 Air conditioner 有权
标题翻译：冷气机
公开(公告)号：US08899056B2
公开(公告)日：2014-12-02
申请号：US12601666
申请日：2008-05-29
申请人： Satoshi Kawano , Masahiro Oka , Kazuhiko Tani , Atsushi Okamoto
发明人： Satoshi Kawano , Masahiro Oka , Kazuhiko Tani , Atsushi Okamoto
IPC分类号： F25B45/00 , F25B13/00 , F25B49/00
CPC分类号： F25B45/00 , F25B13/00 , F25B49/005 , F25B2313/006 , F25B2313/02741 , F25B2700/04 , F25B2700/21163 , F25B2700/21174
摘要： An air conditioner includes a compressor, first and second heat exchangers connected with high pressure piping, low pressure piping connecting the second heat exchanger to a compressor suction port, a pressure reducing mechanism arranged to reduce pressure in the high pressure piping, a bypass passageway, a vessel connected to the bypass passageway, and first and second opening/closing mechanisms. The first heat exchanger is connected to a compressor discharge port. The bypass passageway is arranged to divert refrigerant from the high pressure piping to the low pressure piping without passing through the second heat exchanger. The first opening/closing mechanism is arranged to open/close a first portion of the bypass passageway that connects the high pressure piping to the vessel. The second opening/closing mechanism is arranged to open/close a second portion of the bypass passageway that connects an upper part of the vessel to the low pressure piping.
摘要翻译：空调机包括压缩机，与高压管道连接的第一和第二热交换器，将第二热交换器连接到压缩机吸入口的低压管道，设置成减小高压管道中的压力的减压机构，旁通通道，连接到旁路通道的容器，以及第一和第二打开/关闭机构。第一热交换器连接到压缩机排出口。旁通通道设置成将制冷剂从高压管道转移到低压管道，而不通过第二热交换器。第一打开/关闭机构布置成打开/关闭将高压管道连接到容器的旁路通道的第一部分。第二打开/关闭机构布置成打开/关闭将容器的上部连接到低压管道的旁路通道的第二部分。

17. 发明授权

US08885331B2 Portable electronic apparatus 有权
标题翻译：便携式电子仪器
公开(公告)号：US08885331B2
公开(公告)日：2014-11-11
申请号：US13497399
申请日：2010-09-24
申请人： Keisuke Nonaka , Atsushi Okamoto , Akito Iwai , Kazuhito Fukumasu , Masahiko Nishiwaki
发明人： Keisuke Nonaka , Atsushi Okamoto , Akito Iwai , Kazuhito Fukumasu , Masahiko Nishiwaki
IPC分类号： H02B1/00 , G06F1/16 , H04M1/02
CPC分类号： G06F1/1616 , G06F1/1637 , G06F1/1681 , H04M1/022 , H04M1/0237
摘要： A portable electronic apparatus includes coupled first and second casings with respective image display surfaces, and including a full-closed state where both casings are overlaid on each other, a tilt state where the second casing has been moved from the full-closed state so that the image display surfaces in both casings are exposed and, also, the image display surface in the second casing is inclined with respect to the image display surface in the first casing at an angle of opening which is equal to or more than 90 degrees but less than 180 degrees, and a full-open state where the image display surfaces in both casings are flushed with each other in the same plane, and the portable electronic apparatus being capable of holding the second casing, in attitude, with respect to the first casing in the full-closed state, in the tilt state and in the full-open state.
摘要翻译：一种便携式电子设备包括具有相应图像显示表面的耦合的第一和第二壳体，并且包括两个壳体彼此重叠的全闭合状态，第二壳体已经从全闭合状态移动的倾斜状态，使得露出两个壳体中的图像显示表面，并且第二壳体中的图像显示表面相对于第一壳体中的图像显示表面以等于或大于90度但更小的开口角度倾斜并且两个壳体中的图像显示表面在同一平面内相互冲洗的全开状态，并且便携式电子设备能够以相对于第一壳体的姿态保持第二壳体处于全闭状态，处于倾斜状态和处于全开状态。

18. 发明授权

US08783050B2 Heat source unit 有权
标题翻译：热源单元
公开(公告)号：US08783050B2
公开(公告)日：2014-07-22
申请号：US13264404
申请日：2010-04-16
申请人： Atsushi Okamoto , Shinya Matsuoka , Takuya Kotani
发明人： Atsushi Okamoto , Shinya Matsuoka , Takuya Kotani
IPC分类号： F25B41/00 , F25B49/00 , F25B41/04 , F25B43/00
CPC分类号： F25B45/00 , F25B43/006 , F25B2345/001 , F25B2400/13 , F25B2700/21152
摘要： A time for loading a refrigerant is shortened when a utilization unit of an air conditioner is installed. A heat source unit 1 includes a compressor 100; a heat-source-side heat exchanger 200; a refrigerant regulator 61 storing a refrigerant; an introducing pipe 62 which is a pipe that is branched off from a discharge-side pipe 110 of the compressor 100 and connected to the refrigerant regulator 61, and introduces the refrigerant discharged from the compressor 100 into the refrigerant regulator 61; and a lead-out pipe 63 which is a pipe that is connected from the refrigerant regulator 61 to an intake-side pipe 120 of the compressor 100, and leads out the refrigerant stored in the refrigerant regulator 61 into the intake-side pipe 120.
摘要翻译：当安装空调的使用单元时，缩短制冷剂的装载时间。热源单元1包括压缩机100; 热源侧热交换器200; 存储制冷剂的制冷剂调节器61; 引导管62，其是从压缩机100的排出侧管110分支并连接到制冷剂调节器61的管，并将从压缩机100排出的制冷剂引入制冷剂调节器61; 以及从制冷剂调节器61连接到压缩机100的进气侧配管120的管道的引出管63，将储存在制冷剂调节器61中的制冷剂引出到进气侧配管120中。

19. 发明申请

US20120230687A1 OPTICAL COMMUNICATION SYSTEM 有权
标题翻译：光通信系统
公开(公告)号：US20120230687A1
公开(公告)日：2012-09-13
申请号：US13502887
申请日：2010-10-15
申请人： Atsushi Okamoto , Kazuyuki Morita
发明人： Atsushi Okamoto , Kazuyuki Morita
IPC分类号： H04J14/04
CPC分类号： H04B10/2581 , G02B5/32 , G02B6/14 , G02B6/34 , G02F2/00
摘要： The present invention causes spatial-mode light emitted from an optical fiber (11), which is a multimode fiber, to pass through a photorefractive medium (13). The photorefractive medium (13) includes holograms for signal separation that are written by irradiation of the photorefractive medium with (i) guide light having a wave front identical to the wave front of signal light having a particular spatial mode and (ii) control light. The photorefractive medium includes holograms recorded in a multiplex manner with use of control light having different incidence angles in correspondence with respective spatial modes. For signal separation, irradiating the photorefractive medium (13) with control light (15) having a particular angle separates signal light having a spatial mode corresponding to the incidence angle of the control light (15).
摘要翻译：本发明使得从作为多模光纤的光纤（11）发射的空间模式光通过光折射介质（13）。光折射介质（13）包括用于信号分离的全息图，其通过光折射介质的照射来写入（i）引导具有与具有特定空间模式的信号光的波前相同的波前的光，以及（ii）控制光。光折射介质包括使用与各个空间模式对应的具有不同入射角的控制光以多路复用方式记录的全息图。对于信号分离，用具有特定角度的控制光（15）照射光折射介质（13）分离具有与控制光（15）的入射角对应的空间模式的信号光。

20. 发明授权

US08262893B2 Aluminum plated film, metallic member, and its fabrication method 有权
标题翻译：镀铝膜，金属构件及其制造方法
公开(公告)号：US08262893B2
公开(公告)日：2012-09-11
申请号：US12308684
申请日：2007-06-25
申请人： Hiroyuki Hoshi , Atsushi Okamoto , Setsuo Andou
发明人： Hiroyuki Hoshi , Atsushi Okamoto , Setsuo Andou
IPC分类号： C25D3/00
CPC分类号： C25D11/16 , C25D3/44 , C25D3/66 , C25D3/665 , Y10T428/1259 , Y10T428/12736 , Y10T428/12993
摘要： A plating film is provided with enough hardness before anodic oxidation, which is hard to be damaged during handling, and also the production method of the plating film. This problem can be solved by an aluminum plating film with aluminum concentration of 98 wt. % or lower, and with a Vickers hardness of 250 or higher. The hardness is increased by containing oxygen, carbon, sulfur, and a halogen element as impurities. The impurity concentration is controlled by adjusting the current density, the plating temperature, or the plating bath composition.
摘要翻译：电镀膜在阳极氧化之前具有足够的硬度，在处理过程中难以损坏，以及镀膜的制造方法。该问题可以通过铝浓度为98重量％的铝电镀膜来解决。％以下，维氏硬度为250以上。通过含有氧，碳，硫和作为杂质的卤素元素来增加硬度。通过调整电流密度，电镀温度或镀液组成来控制杂质浓度。

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