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1. 发明申请

US20050043304A1 Novel amine derivative having human beta-tryptase inhibitory activity and drugs containing the same 审中-公开
标题翻译：具有人β-胰蛋白酶抑制活性的新型胺衍生物和含有它们的药物
公开(公告)号：US20050043304A1
公开(公告)日：2005-02-24
申请号：US10485331
申请日：2002-08-01
申请人： Yutaka Kato , Yutaka Miyazaki , Hiroyasu Shimada , Tadashi Manabe , Ikuya Shiromizu , Atsushi Okamoto
发明人： Yutaka Kato , Yutaka Miyazaki , Hiroyasu Shimada , Tadashi Manabe , Ikuya Shiromizu , Atsushi Okamoto
IPC分类号： A61K31/137 , A61K31/166 , A61K31/18 , A61K31/381 , A61K31/428 , A61K31/47 , A61K31/472 , A61P1/00 , A61P9/00 , A61P11/00 , A61P11/06 , A61P17/00 , A61P27/14 , A61P27/16 , A61P29/00 , A61P37/08 , A61P43/00 , C07C233/78 , C07C311/18 , C07D209/08 , C07D209/20 , C07D215/48 , C07D217/02 , C07D235/08 , C07D307/82 , C07D307/85 , C07D317/62 , C07D333/62 , C07D401/12 , C07D409/12 , C07D251/48 , A61K31/497 , A61K31/53 , C07D237/02
CPC分类号： C07D307/82 , A61K31/137 , A61K31/166 , A61K31/18 , A61K31/381 , A61K31/428 , A61K31/47 , A61K31/472 , C07C233/78 , C07C311/18 , C07C2602/08 , C07D209/08 , C07D209/20 , C07D215/48 , C07D217/02 , C07D235/08 , C07D307/85 , C07D317/62 , C07D333/62 , C07D401/12 , C07D409/12
摘要： It is intended to provide a novel low-molecular weight amine derivative, that is absorbed well, has low toxicity, and has an excellent human β-tryptase inhibitory activity with extremely high selectivity, a pharmaceutically acceptable salt thereof, and a medicine containing the same as an active ingredient. The medicine of the present invention is efficacious as a prophylactic/therapeutic agent for diseases in the crisis and evolution of which are considered to be attributed to β-tryptase, for example, respiratory diseases, allergic diseases, inflammatory bowel diseases, hyperprolliferative skin diseases, vascular edema and rheumatoid arthritis.
摘要翻译：旨在提供一种新颖的低分子量胺衍生物，其被良好吸收，具有低毒性，并且具有极高选择性的优异的人β-类胰蛋白酶抑制活性，其药学上可接受的盐和含有它们的药物作为活性成分。本发明的药物作为危机中的疾病的预防/治疗剂是有效的，其进化被认为归因于β-类胰蛋白酶，例如呼吸系统疾病，过敏性疾病，炎性肠病，过度增生性皮肤病，血管性水肿和类风湿性关节炎。

2. 发明授权

US06710060B2 4-hydroxypiperidine derivatives having antiarrhythmic activity 失效
标题翻译：具有抗心律不齐活性的4-羟基哌啶衍生物
公开(公告)号：US06710060B2
公开(公告)日：2004-03-23
申请号：US09969639
申请日：2001-10-04
申请人： Ichiro Yamamoto , Manabu Itoh , Fumiaki Yamasaki , Yutaka Miyazaki , Shinichi Ogawa
发明人： Ichiro Yamamoto , Manabu Itoh , Fumiaki Yamasaki , Yutaka Miyazaki , Shinichi Ogawa
IPC分类号： A61K31445
CPC分类号： C07D405/06 , C07D211/48 , C07D407/06 , C07D409/06
摘要： The present invention relates to a compound represented by the following formula (I) or a salt thereof, or a pharmaceutical composition containing the compound as an effective ingredient: (wherein A represents, for example, phenyl group substituted with R1 and R2 or unsubstituted thienyl group; R1 and R2 each independently represent, for example, hydrogen atom, halogen atom or lower alkoxycarbonyl group; R3 represents, for example, hydrogen atom; R4 represents, for example, lower alkyl group; R5 represents, for example, lower alkoxy group; R6 represents, for example, hydrogen atom; R7 and R8 each represent, for example, hydrogen atom, respectively; X represents, for example, a single bond; Y represents, for example, methylene group or benzylidene group substituted with R1; and Z represents, for example, methylene group.) The compounds according to the present invention that do not suppress the transient sodium current of the cardiac muscle and do not manifest proarrhythimic activity is useful as a therapeutic agent for preventing and/or treating arrhythimia and for preventing sudden death.
摘要翻译：本发明涉及由下式（I）表示的化合物或其盐或含有该化合物作为有效成分的药物组合物：（其中A表示例如被R 1和R 2取代的苯基） 2或未取代的噻吩基; R 1和R 2各自独立地表示例如氢原子，卤素原子或低级烷氧基羰基; R 3表示例如氢原子; R 4，表示例如低级烷基; R 5表示例如低级烷氧基; R 6表示例如氢原子; R 7和R 8各自表示例如氢原子; X表示例如单键; Y表示例如被R 1取代的亚甲基或亚苄基; Z表示例如亚甲基。）根据本发明的化合物不抑制心肌的瞬时钠电流，并不表现出血浆节奏活动可用作预防和/或治疗心律失常并用于预防猝死的治疗剂。

3. 发明申请

US20130183571A1 BATTERY PACK AND VEHICLE INCLUDING THE SAME 审中-公开
标题翻译：电池包和车辆包括它
公开(公告)号：US20130183571A1
公开(公告)日：2013-07-18
申请号：US13822885
申请日：2011-09-27
申请人： Yutaka Miyazaki , Shingo Ochi , Atsushi Fujita
发明人： Yutaka Miyazaki , Shingo Ochi , Atsushi Fujita
IPC分类号： H01M2/20
CPC分类号： H01M2/20 , H01M2/1077 , H01M10/0481 , H01M10/613 , H01M10/625 , H01M10/647 , H01M10/6555 , H01M10/6556 , H01M10/6557 , H01M10/6568 , H01M10/66 , H01M2220/20
摘要： A battery pack includes a battery assembly constructed of rectangular battery cells that are arranged side by side. End plates are arranged on the end surface of the assembly. Metal bind bars securely hold the assembly and the plates. Each bar includes bent parts that are formed by bending the both bar end parts toward a common direction. The bar is formed in a substantially rectangular U shape as viewed from the bar edge side The bent parts on the both bar ends are coupled to the plates so that the assembly is interposed and secured between the plates. A bent-part-side engagement structure is formed in a coupling area of the bent part of the bar. An end-plate-side engagement structure is positioned in the plate to face the bent part. When the bent-part-side and end-plate-side engagement structures engage with each other, the bar is fastened to the plates.
摘要翻译：电池组包括由并排布置的矩形电池单元构成的电池组件。端板布置在组件的端表面上。金属结合杆牢固地固定组件和板。每个杆包括通过将两个杆端部朝向共同方向弯曲而形成的弯曲部分。杆从杆边缘侧观察时形成为大致矩形的U形。两个杆端部上的弯曲部分联接到板上，使得组件插入并固定在板之间。弯曲部分侧接合结构形成在杆的弯曲部分的联接区域中。端板侧接合结构定位在板中以面对弯曲部分。当弯曲部分侧和端板侧接合结构彼此接合时，杆紧固到板上。

4. 发明授权

US07080251B2 Certificate validity authentication method and apparatus 有权
公开(公告)号：US07080251B2
公开(公告)日：2006-07-18
申请号：US09941771
申请日：2001-08-30
申请人： Takahiro Fujishiro , Satoru Tezuka , Yoko Kumagai , Tomoharu Morio , Yutaka Miyazaki
发明人： Takahiro Fujishiro , Satoru Tezuka , Yoko Kumagai , Tomoharu Morio , Yutaka Miyazaki
IPC分类号： G06F17/00
CPC分类号： H04L9/3268 , H04L9/006 , H04L2209/60
摘要： A time period which is expended since a request for the authentication of the validity of a public key certificate till the authentication of the validity, is shortened. A certificate validity authentication center VC periodically searches for and verifies paths which extend from a bridge certification authority CAbridge to individual terminal admitting certification authorities CA, and it registers the paths whose verifications have held good, in a path database in association with the respective terminal admitting certification authorities CA. Besides, in a case where the request for the authentication of the validity of a certificate has been made by an end entity EE, whether or not a path associated with the terminal admitting certification authority CA which admits the end entity, and a path associated with the terminal admitting certification authority CA which has issued the certificate being a subject for the request are registered in the path database is checked, and the subject certificate is judged valid only when both the paths are registered.

5. 发明申请

US20130200700A1 BATTERY MODULE, BATTERY SYSTEM, ELECTRIC VEHICLE, MOVABLE BODY, POWER STORAGE DEVICE, POWER SUPPLY DEVICE, AND ELECTRICAL EQUIPMENT 审中-公开
标题翻译：电池模块，电池系统，电动车，可动体，蓄电装置，电源装置和电气设备
公开(公告)号：US20130200700A1
公开(公告)日：2013-08-08
申请号：US13581066
申请日：2011-02-24
申请人： Kazumi Ohkura , Yoshitomo Nishihara , Yutaka Miyazaki , Yasuhiro Asai
发明人： Kazumi Ohkura , Yoshitomo Nishihara , Yutaka Miyazaki , Yasuhiro Asai
IPC分类号： H02J7/00 , H01M10/48 , B60L11/18
CPC分类号： H02J7/0029 , B60L50/64 , G01R1/203 , G01R31/3842 , G01R31/396 , H01M2/206 , H01M10/4207 , H01M10/425 , H01M10/48 , H01M10/482 , H01M10/613 , H01M10/625 , H01M10/647 , H01M10/6551 , H01M10/6556 , H01M10/6563 , H01M2200/108 , H01M2200/20 , H02J7/0016 , H02J7/0063 , Y02T10/7055
摘要： A battery module includes a battery block and a printed circuit board. The battery block includes a plurality of laminated battery cells. A detection circuit and an amplification circuit are mounted on the printed circuit board. In the battery block, a bus bar is attached to electrodes of the two battery cells in close proximity to each other so that the plurality of battery cells are connected in series. The bus bar attached to one of the electrodes of the battery cell at one end of the battery block is used as a shunt resistor for current detection. The detection circuit detects a voltage between both ends of the shunt resistor, which has been amplified by the amplification circuit.
摘要翻译：电池模块包括电池块和印刷电路板。电池块包括多个叠层电池单元。检测电路和放大电路安装在印刷电路板上。在电池块中，将母线彼此靠近地连接到两个电池单元的电极，使得多个电池单元串联连接。在电池块的一端连接到电池单元的一个电极的母线被用作用于电流检测的分流电阻器。检测电路检测分路电阻的两端之间的电压，该电压已被放大电路放大。

6. 发明申请

US20110206948A1 POWER SOURCE APPARATUS WITH ELECTRICAL COMPONENTS DISPOSED IN THE BATTERY BLOCKS 审中-公开
标题翻译：电源组件中电气组件的电源设备
公开(公告)号：US20110206948A1
公开(公告)日：2011-08-25
申请号：US13032046
申请日：2011-02-22
申请人： Yasuhiro Asai , Yoshimoto Nishihara , Kazumi Ohkura , Yutaka Miyazaki
发明人： Yasuhiro Asai , Yoshimoto Nishihara , Kazumi Ohkura , Yutaka Miyazaki
IPC分类号： H01M10/42
CPC分类号： H01M2/1077 , H01M2/0473 , H01M2/206 , H01M10/0525 , H01M10/425 , H01M10/482 , H01M10/613 , H01M10/617 , H01M10/625 , H01M10/647 , H01M10/652 , H01M10/653 , H01M10/6554 , H01M10/6556 , H01M10/6563 , H01M10/6566 , H01M10/6568 , Y02E60/122
摘要： The power source apparatus is provided with battery blocks 50 made up of a plurality of battery cells 1 connected in battery stacks, and an outer case that holds the battery blocks 50. A block circuit board 60 to control the battery cells 1 that make up each battery stack and electrical components 63 connected to the block circuit board 60 or the battery stack are disposed in the end-planes of each battery stack. With this arrangement, electrical components are disposed in each battery block eliminating the need for a special purpose electrical component case and allowing outer case enlargement to be avoided.
摘要翻译：电源装置设置有由连接在电池堆中的多个电池单元1和保持电池块50的外壳构成的电池块50.块电路板60，用于控制构成每个电池单元1的电池单元1 连接到块电路板60或电池组的电池组和电气部件63设置在每个电池组的端面中。通过这种布置，电气部件被布置在每个电池块中，消除了对专用电气部件壳体的需要，并且可以避免外部扩大。

7. 发明申请

US20060242413A1 Certificate validity authentication method and apparatus 有权
标题翻译：证书有效性认证方法和设备
公开(公告)号：US20060242413A1
公开(公告)日：2006-10-26
申请号：US11452299
申请日：2006-06-14
申请人： Takahiro Fujishiro , Satoru Tezuka , Yoko Kumagai , Tomoharu Morio , Yutaka Miyazaki
发明人： Takahiro Fujishiro , Satoru Tezuka , Yoko Kumagai , Tomoharu Morio , Yutaka Miyazaki
IPC分类号： H04L9/00
CPC分类号： H04L9/3268 , H04L9/006 , H04L2209/60
摘要： A time period which is expended since a request for the authentication of the validity of a public key certificate till the authentication of the validity, is shortened. A certificate validity authentication center VC periodically searches for and verifies paths which extend from a bridge certification authority CAbridge to individual terminal admitting certification authorities CA, and it registers the paths whose verifications have held good, in a path database in association with the respective terminal admitting certification authorities CA. Besides, in a case where the request for the authentication of the validity of a certificate has been made by an end entity EE, whether or not a path associated with the terminal admitting certification authority CA which admits the end entity, and a path associated with the terminal admitting certification authority CA which has issued the certificate being a subject for the request are registered in the path database is checked, and the subject certificate is judged valid only when both the paths are registered.
摘要翻译：缩短了对认证有效期之后的公开密钥证书的有效性的认证请求消耗的时间段。证书有效性认证中心VC定期搜索并验证从桥接认证机构CA 桥接延伸到接收认证机构CA的个人终端的路径，并将验证已经保持良好的路径注册在路径中数据库与相应的终端接收认证机构CA。此外，在由终端实体EE对证书的有效性进行认证的请求的情况下，是否允许与接收终端实体的认证机构CA相关联的路径以及与终端实体相关联的路径在路径数据库中注册已经发出作为该请求的主题的证书的终端的认证机构CA，并且只有当两个路径都被注册时，被认证证书才被认定为有效。

8. 发明授权

US08206847B2 Battery pack having intercell connector and manufacturing method thereof 失效
标题翻译：具有电池间连接器的电池组及其制造方法
公开(公告)号：US08206847B2
公开(公告)日：2012-06-26
申请号：US11905062
申请日：2007-09-27
申请人： Yutaka Miyazaki
发明人： Yutaka Miyazaki
IPC分类号： H01M2/22 , H01M6/42
CPC分类号： H01M2/204 , H01M2/1022 , H01M6/42 , Y10T29/49108
摘要： A battery pack couples first and second batteries mutually linearly via a connector of a metallic plate. The connector formed of a tube with a bottom is composed of a bottom portion and a side wall. Regarding the bottom portion, an outer periphery is welded to a bottom wall of a second battery casing, while an inner periphery inwardly of the outer periphery is welded to a sealing plate of the first battery. The side wall of the connector, protruded toward the first battery, has an inner diameter larger than an outer diameter at an end portion of the first battery. Regarding the battery pack, the end portion of the first battery is inserted inside the side wall of the connector in a non-contact state, and the bottom portion is welded to the first and second batteries, thus the first and second batteries being mutually coupled by the connector.
摘要翻译：电池组通过金属板的连接器相互线性地耦合第一和第二电池。由具有底部的管形成的连接器由底部和侧壁构成。关于底部，外周被焊接到第二电池壳体的底壁，而外周向内的内周边焊接在第一电池的密封板上。朝向第一电池突出的连接器的侧壁的内径大于第一电池的端部处的外径。关于电池组，第一电池的端部以非接触状态插入连接器的侧壁内部，并且底部焊接到第一和第二电池，因此第一和第二电池相互耦合通过连接器。

9. 发明授权

US07409551B2 Certificate validity authentication method and apparatus 有权
标题翻译：证书有效性认证方法和设备
公开(公告)号：US07409551B2
公开(公告)日：2008-08-05
申请号：US11452299
申请日：2006-06-14
申请人： Takahiro Fujishiro , Satoru Tezuka , Yoko Kumagai , Tomoharu Morio , Yutaka Miyazaki
发明人： Takahiro Fujishiro , Satoru Tezuka , Yoko Kumagai , Tomoharu Morio , Yutaka Miyazaki
IPC分类号： H04L9/00
CPC分类号： H04L9/3268 , H04L9/006 , H04L2209/60
摘要： A time period which is expended since a request for the authentication of the validity of a public key certificate till the authentication of the validity, is shortened. A certificate validity authentication center VC periodically searches for and verifies paths which extend from a bridge certification authority CAbridge to individual terminal admitting certification authorities CA, and it registers the paths whose verifications have held good, in a path database in association with the respective terminal admitting certification authorities CA. Besides, in a case where the request for the authentication of the validity of a certificate has been made by an end entity EE, whether or not a path associated with the terminal admitting certification authority CA which admits the end entity, and a path associated with the terminal admitting certification authority CA which has issued the certificate being a subject for the request are registered in the path database is checked, and the subject certificate is judged valid only when both the paths are registered.
摘要翻译：缩短了对认证有效期之后的公开密钥证书的有效性的认证请求消耗的时间段。证书有效性认证中心VC定期搜索并验证从桥接认证机构CA 桥接延伸到接收认证机构CA的个人终端的路径，并将验证已经保持良好的路径注册在路径中数据库与相应的终端接收认证机构CA。此外，在由终端实体EE对证书的有效性进行认证的请求的情况下，是否允许与接收终端实体的认证机构CA相关联的路径以及与终端实体相关联的路径在路径数据库中注册已经发出作为该请求的主题的证书的终端的认证机构CA，并且只有当两个路径都被注册时，被认证证书才被认定为有效。

10. 发明申请

US20080081252A1 Battery pack and manufacturing method thereof 失效
标题翻译：电池组及其制造方法
公开(公告)号：US20080081252A1
公开(公告)日：2008-04-03
申请号：US11905062
申请日：2007-09-27
申请人： Yutaka Miyazaki
发明人： Yutaka Miyazaki
IPC分类号： H01M10/36 , H01M10/38
CPC分类号： H01M2/204 , H01M2/1022 , H01M6/42 , Y10T29/49108
摘要： A battery pack couples first and second batteries mutually linearly via a connector of a metallic plate. The connector formed of a tube with a bottom is composed of a bottom portion and a side wall. Regarding the bottom portion, an outer periphery is welded to a bottom wall of a second battery casing, while an inner periphery inwardly of the outer periphery is welded to a sealing plate of the first battery. The side wall of the connector, protruded toward the first battery, has an inner diameter larger than an outer diameter at an end portion of the first battery. Regarding the battery pack, the end portion of the first battery is inserted inside the side wall of the connector in a non-contact state, and the bottom portion is welded to the first and second batteries, thus the first and second batteries being mutually coupled by the connector.
摘要翻译：电池组通过金属板的连接器相互线性地耦合第一和第二电池。由具有底部的管形成的连接器由底部和侧壁构成。关于底部，外周被焊接到第二电池壳体的底壁，而外周向内的内周边焊接在第一电池的密封板上。朝向第一电池突出的连接器的侧壁的内径大于第一电池的端部处的外径。关于电池组，第一电池的端部以非接触状态插入连接器的侧壁内部，并且底部焊接到第一和第二电池，因此第一和第二电池相互耦合通过连接器。

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