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    • 11. 发明授权
    • Compositions of polyvinyl chloride and tetracarboxylic tetraesters and
medical articles thereof
    • 聚氯乙烯和四羧酸四酯的组合物及其医药制品
    • US4560720A
    • 1985-12-24
    • US542355
    • 1983-10-17
    • Juuro AoyagiToshiji IchikawaMikio KoideTakeshi Shimomura
    • Juuro AoyagiToshiji IchikawaMikio KoideTakeshi Shimomura
    • A61L29/00A61J1/00A61J1/05C08K5/12C08K5/375C08K5/41C08K5/10
    • A61J1/10C08K5/12C08K5/375C08K5/41
    • Medical articles made of a resin composition comprising a polyvinyl chloride and a tetracarboxylic tetraester are provided. As examples of the tetracarboxylic tetraester are mentioned tetra(2-ethylhexyl) 3,3',4,4'-biphenylethertetracarboxylate, tetra(2-ethylhexyl) 3,3',4,4'-biphenylmethanetetracarboxylate, tetra(n-dodecyl) 2,3,3',4'-biphenyl-1,1-ethanetetracarboxylate, tetra(2-ethylhexyl) 3,3',4,4'-biphenyl-2,2-propanetetracarboxylate and the like. The tetracarboxylic tetraester is incorporated in an amount from 20 to 120, preferably from 30 to 100 parts by weight per 100 parts by weight of the polyvinyl chloride. As dissolution and migration to the surface of the article of the plasticizer tetracarboxylic tetraester are low in the medical articles, said medical articles produce no adverse effects upon body fluids such as blood when contacted. Examples of preferred medical articles are blood preservation vessels, catheters and blood transfusion sets.
    • 提供由包含聚氯乙烯和四羧酸四酯的树脂组合物制成的医疗制品。 提到四羧酸四酯的四(2-乙基己基)3,3',4,4'-联苯基醚四羧酸四(2-乙基己基)3,3',4,4'-联苯甲烷四羧酸四(正十二烷基)酯, 2,3,3',4'-联苯-1,1-乙烷四羧酸酯,3,3',4,4'-联苯基-2,2-丙烷四羧酸四(2-乙基己基)酯,4,4'-联苯基-2,2-丙烷四羧酸酯等。 四羧酸四酯的含量为每100重量份聚氯乙烯20至120重量份,优选30至100重量份。 由于溶解和向塑化剂四羧酸四酯的制品的表面迁移到医疗制品中,所以医疗制品在接触时不会对体液如血液产生不利影响。 优选医疗制品的实例是保血管,导管和输血组。