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11. 发明授权

US06790282B2 Lane maintenance machine with mechanical lane dressing application controller 失效
标题翻译：车道维修机具有机械车道修整应用控制器
公开(公告)号：US06790282B2
公开(公告)日：2004-09-14
申请号：US10458462
申请日：2003-06-10
申请人： Mark E. Davis , John M. Davis
发明人： Mark E. Davis , John M. Davis
IPC分类号： B05C2100
CPC分类号： A47L11/4011 , A47L11/03 , A47L11/185 , A47L11/4069 , A47L11/4088 , A63D5/10
摘要： A machine for automatically applying lane dressing travels up and down the lane to apply dressing according to a certain predetermined and preselected pattern. A single dispensing head travels back and forth across the lane as the machine moves linearly along the lane so that dressing is transferred to a buffer brush that engages the lane surface and applies the dressing thereto. The oil pattern is determined by actuation and deactuation of the dispensing head as it traverses the lane, such control of the head being provided by a special pattern control device in the nature of a cylindrical pattern tube that extends alongside the path of travel of the dispensing head. A sensor on the dispensing head detects pattern structure on the control device to responsively actuate and deactuate the head. In a preferred form, such structure takes the form of a series of metallic strips extending parallel to the path of travel of the dispensing head and spaced circumferentially around the periphery of the pattern tube. The sensor on the dispensing head is in the form of a proximity sensor that responds to the presence and absence of such metallic strips. At the end of each traverse of the dispensing head, the pattern tube is indexed one rotative increment to present the next strip into position for detection by the sensor during the succeeding traverse by dispensing head.
摘要翻译：用于自动施加车道敷料的机器沿着车道上下行驶，以根据预定和预先选定的模式进行敷料。当机器沿着车道线性移动时，单个分配头在车道上前后移动，使得敷料被转移到与车道表面接合的缓冲刷，并将敷料施加到其上。通过分配头在穿过通道时的致动和停止来确定油图案，这种头部的控制由特殊的图案控制装置提供，其特征在于圆柱形图案管的特性，其与分配的行进路径一起延伸头。分配头上的传感器检测控制装置上的图案结构以响应地致动和停止头部。在优选形式中，这种结构采取一系列平行于分配头的行进路径延伸并且围绕图案管的周边周向间隔开的一系列金属条的形式。分配头上的传感器是接近传感器的形式，其响应于这种金属条的存在和不存在。在分配头的每个横移结束时，图案管被转动一个旋转增量，以将下一个条带放置在位置，以便在后续通过分配头移动期间由传感器检测。

12. 发明授权

US5181290A Bowling lane maintenance machine 失效
标题翻译：保龄球道保养机
公开(公告)号：US5181290A
公开(公告)日：1993-01-26
申请号：US893660
申请日：1992-06-05
申请人： John M. Davis , Mark E. Davis , David G. Jennings
发明人： John M. Davis , Mark E. Davis , David G. Jennings
IPC分类号： A47L11/10
CPC分类号： A47L11/4011 , A47L11/10 , A47L11/4066 , A47L11/408 , A47L2201/04 , A47L2201/06
摘要： The oil pattern laid down by the automatic machine across the width of the lane and along the length of the lane can be precisely controlled and varied through the use of a series of independently controllable wick assemblies that are individually movable into and out of contacting engagement with the oil applicator of the machine. A programmable controller for the wick assemblies determines which of the wick assemblies will be in oil-transferring contact with the applicator and when.
摘要翻译：通过自动机器跨越车道宽度和沿着车道的长度铺设的油图案可以通过使用一系列可独立控制的油绳组件被精确地控制和变化，这些独立可控的油绳组件可独立地移动进入和离开与机器的涂油器。用于芯组件的可编程控制器确定哪个芯组件将与涂布器油传输接触以及什么时候。

13. 发明申请

US20120208719A1 ASSESSING RHEUMATOID ARTHRITIS 审中-公开
标题翻译：评估湿疹风湿性关节炎
公开(公告)号：US20120208719A1
公开(公告)日：2012-08-16
申请号：US13502317
申请日：2010-10-13
申请人： Sherine E. Gabriel , Keith L. Knutson , Larry R. Pease , John M. Davis
发明人： Sherine E. Gabriel , Keith L. Knutson , Larry R. Pease , John M. Davis
IPC分类号： C40B30/04
CPC分类号： G01N33/6863 , G01N33/564 , G01N2800/102 , G01N2800/56
摘要： This document provides methods and materials related to assessing mammals (e.g., humans) with arthritis (e.g., RA). For example, methods and materials for using cytokine response profiles to assist clinicians in assessing RA disease activity, assessing the likelihood of response and outcomes of RA therapy, predicting long-term RA disease outcomes, and assessing the risk of developing heart conditions are provided. Methods and materials for using cytokine response profiles to assist clinicians in diagnosing arthritis (e.g., RA) also are provided.
摘要翻译：本文件提供了与评估具有关节炎（例如RA）的哺乳动物（例如，人）相关的方法和材料。例如，提供了使用细胞因子应答谱辅助临床医师评估RA疾病活动，评估RA治疗的反应和结果的可能性，预测长期RA疾病结果以及评估发展心脏病的风险的方法和材料。还提供了使用细胞因子应答谱辅助临床医师诊断关节炎（如RA）的方法和材料。

14. 发明授权

US07472166B1 Assisting users with web pages 有权
标题翻译：协助用户网页
公开(公告)号：US07472166B1
公开(公告)日：2008-12-30
申请号：US09652432
申请日：2000-08-31
申请人： John M. Davis
发明人： John M. Davis
IPC分类号： G06F15/16
CPC分类号： G06F9/453
摘要： A system enables a service provider to provide real time, on-line help to a web page user. When the web page user initiates a help request, a client agent may automatically provide a service provider with information, about the particular web page that is causing the problem, sufficient to enable the service provider to access the web page. The agent also initiates a chat session between the service provider and the client. In this way, the service provider can see the actual web page that is causing the problem and may communicate through the chat session channel with the user. In one embodiment, a chat session dialog box may overlie the associated web page.
摘要翻译：系统使服务提供商能够向网页用户提供实时的在线帮助。当网页用户发起帮助请求时，客户端代理可以自动向服务提供商提供关于导致该问题的特定网页的足以使服务提供商访问该网页的信息。代理还启动服务提供商和客户端之间的聊天会话。以这种方式，服务提供商可以看到导致问题的实际网页，并且可以通过聊天会话信道与用户进行通信。在一个实施例中，聊天会话对话框可以覆盖相关联的网页。

15. 发明授权

US09138286B2 Ultrasound detectable interventional medical device 有权
标题翻译：超声检测介入医疗器械
公开(公告)号：US09138286B2
公开(公告)日：2015-09-22
申请号：US12288427
申请日：2008-10-20
申请人： John M. Davis , Patrick J. LePivert
发明人： John M. Davis , Patrick J. LePivert
IPC分类号： A61B18/14 , A61B19/00 , A61B10/02 , A61B18/02
CPC分类号： A61B18/1477 , A61B10/0233 , A61B18/02 , A61B2090/3925 , A61B2090/3929
摘要： An interventional medical device for use with a motion-sensitive ultrasonic imaging system comprising a flexible elongated member for insertion into soft tissue, a two-axis, flexing mechanism coupled to the flexible elongated member and a mechanism for controlled electrical excitation of the flexible elongated member. Each of the axial flexing mechanisms, when acted upon by electrical excitation, forcibly bends the elongated member along a section of it length causing its tip to move in the plane of the applied bending force. As a direct result of direct energy coupling by bending rather than vibration, the relative phases of the two axes can be controlled to accomplish specific movement of the tip of the flexible elongated member.
摘要翻译：一种与运动敏感超声成像系统一起使用的介入医疗装置，包括用于插入软组织的柔性细长构件，联接到柔性细长构件的两轴弯曲机构和用于柔性细长构件的受控电激励的机构。当通过电激励作用时，每个轴向弯曲机构强制地使细长构件沿其长度的一部分弯曲，导致其尖端在所施加的弯曲力的平面内移动。作为通过弯曲而不是振动的直接能量耦合的直接结果，可以控制两个轴的相对相位以实现柔性细长构件的尖端的特定运动。

16. 发明申请

US20120216952A1 Polyurethane Formulation With High Green Strength and Gunnability 有权
标题翻译：具有高绿色强度和可植入性的聚氨酯配方
公开(公告)号：US20120216952A1
公开(公告)日：2012-08-30
申请号：US13498042
申请日：2010-08-27
申请人： Paula Bushendorf , John M. Davis , Michael Porsch
发明人： Paula Bushendorf , John M. Davis , Michael Porsch
IPC分类号： C09J175/12 , C09D5/16 , C08K5/3492 , C08K3/18 , C08K5/10 , C08K3/36 , C08K3/22 , C08K3/30 , C08F2/44 , C08L75/12 , C08K3/34
CPC分类号： C08K5/21 , C08G18/10 , C08G18/2865 , C08G18/7664 , C09J175/04 , Y10T428/31551 , C08L75/04 , C08G18/307 , C08G18/3829
摘要： A moisture-curable polyurethane formulation is provided capable of curing to form a reaction product, having high green strength and being dispensable from a caulking gun. The polyurethane formulation comprises at least one isocyanate-terminated prepolymer, at least one rheology modifier or filler, optionally monomeric/polymeric isocyanate, and at least one urea-based thixotropic additive added to the formulation or formed in situ, to provide greater than 1% of urea groups in the reaction product. A method for making a moisture-curable polyurethane formulation capable of curing to form a reaction product and methods of bonding materials together using the formulation are also provided.
摘要翻译：提供了能够固化以形成具有高绿色强度并且可以从填缝枪分配的反应产物的可湿气固化的聚氨酯配方。聚氨酯制剂包含至少一种异氰酸酯封端的预聚物，至少一种流变改性剂或填料，任选的单体/聚合异氰酸酯，以及至少一种基于尿素的触变添加剂，添加到制剂中或原位形成，以提供大于1％的尿素基团。还提供了一种制备能够固化以形成反应产物的湿固化性聚氨酯配方的方法和使用所述制剂将材料粘合在一起的方法。

17. 发明授权

US06740500B1 Method of screening for non-steroidal neuropsychiatric agents 失效
标题翻译：非甾体类神经精神药物筛选方法
公开(公告)号：US06740500B1
公开(公告)日：2004-05-25
申请号：US09534831
申请日：2000-03-23
申请人： John M. Davis , Doncho P. Uzunov
发明人： John M. Davis , Doncho P. Uzunov
IPC分类号： G01N33567
CPC分类号： G01N33/743 , C12Q1/26 , G01N33/6896
摘要： A method of screening for non-steroidal neuropsychiatric agents includes determining the ability of a candidate non-steroidal agent to selectively regulate or alter the central nervous system content and/or bioavailability of an endogenous neuroactive steroid. In particular, the method includes determining the ability of the agent to selectively regulate a rate-limiting step in the bio-control of the bioavailable amount of an endogenous neuroactive steroid, wherein the rate-limiting step may be either a step in biosynthesis of an endogenous neuroactive steroid, such as allopregnanolone, or a step in the biodegradation of such an endogenous neuroactive steroid. Alternatively, the method may include determining the ability of a candidate agent in selectively regulating the rate of reuptake of an endogenous neuroactive steroid by neurons or glial cells.
摘要翻译：筛选非甾体神经精神药物的方法包括确定候选非甾体药物选择性调节或改变内源性神经活性类固醇的中枢神经系统含量和/或生物利用度的能力。特别地，该方法包括确定试剂选择性调节内源性神经活性类固醇生物可利用量的生物控制中的限速步骤的能力，其中速率限制步骤可以是生物合成中的步骤内源性神经活性类固醇，例如allopregnanolone，或这种内源性神经活性类固醇生物降解的步骤。或者，该方法可以包括确定候选药剂选择性调节由神经元或神经胶质细胞再生内源性神经活性类固醇的速率的能力。

18. 发明授权

US06407667B1 Alarm system for forgotten golf club 失效
标题翻译：被遗忘的高尔夫球杆报警系统
公开(公告)号：US06407667B1
公开(公告)日：2002-06-18
申请号：US09522650
申请日：2000-03-10
申请人： Susan M. Jackson , Robert A. Jackson , John M. Davis
发明人： Susan M. Jackson , Robert A. Jackson , John M. Davis
IPC分类号： G08B1314
CPC分类号： A63B55/10 , A63B57/50 , A63B2055/402 , G08B13/1427 , G08B21/023 , G08B21/0247 , G08B21/0288
摘要： An alarm system is provided for alerting a golfer about a forgotten club. A divot tool incorporates a radio transmitter powered by a rechargeable power source for transmitting a coded transmission. A radio receiver tuned to receive the coded transmission includes logic circuitry that generates an alarm signal whenever power associated with the coded transmission drops below a threshold level. One or more alarm devices are coupled to the logic circuitry to generate alarm(s) when the alarm signal is supplied thereto. A power source is coupled to the radio receiver for supplying power thereto and for supplying a charging current for the rechargeable power source via an electrical coupling. When a golfer places a club or other accessory on the ground, the divot tool is placed near the club. As long as the golfer remains within a prescribed range, no alarm will be activated. However, if the golfer moves further from the divot tool than the prescribed range, an alarm is produced. Alerted to his forgetfulness before leaving the vicinity, the golfer then simply retrieves the club and divot tool.
摘要翻译：提供了一个报警系统来提醒高尔夫球手关于被遗忘的俱乐部。一个divot工具包含由可充电电源供电的无线电发射机，用于发送编码的传输。被调谐以接收编码传输的无线电接收机包括逻辑电路，每当与编码传输相关联的功率下降到阈值以下时，该电路产生报警信号。一个或多个报警装置耦合到逻辑电路，以在向其提供报警信号时产生报警。电源耦合到无线电接收机，用于向其提供电力，并通过电耦合为可再充电电源提供充电电流。高尔夫球手将俱乐部或其他配件放置在地面上时，该工具会放置在俱乐部附近。只要高尔夫球手保持在规定的范围内，就不会激活报警。但是，如果高尔夫球手从深度刀具进一步移动到规定范围以外，则产生报警。离开附近之前忘记了他的健忘，然后高尔夫球手就简单地取回了俱乐部和工具。

19. 发明授权

US5217335A Plastic lens generator and method 失效
标题翻译：塑料镜头发生器和方法
公开(公告)号：US5217335A
公开(公告)日：1993-06-08
申请号：US513628
申请日：1990-04-24
申请人： Lewis D. Houchens, Jr. , John M. Davis
发明人： Lewis D. Houchens, Jr. , John M. Davis
IPC分类号： B24B13/06 , G05B19/25
CPC分类号： B24B13/06 , G05B19/251 , Y10T409/300896 , Y10T409/30392 , Y10T409/305712
摘要： The generator for plastic lenses comprises a rotatable chuck for rotating an optical lens blank on a first axis. A drive system displaces the chuck and thereby the lens blank generally transverse to the first axis. A cutter is operably associatable with the chuck for engaging the lens blank and causing shaping thereof. The cutter includes a high speed rotary element rotatable on a second axis angularly disposed relative to the first axis. A second drive system for selectively displacing the cutter parallel to the first axis is provided. A computer control is operably associated with the first and second drive systems for coordinating displacement of the associated chuck and cutter for causing a selected curvature to be generated on the blank.

20. 发明授权

US08697188B2 Polyurethane systems having non-sag and paintability 失效
标题翻译：聚氨酯系统具有不下垂和可涂漆性
公开(公告)号：US08697188B2
公开(公告)日：2014-04-15
申请号：US13558408
申请日：2012-07-26
申请人： Chia L. Wang , John M. Davis , Bryan Lienke
发明人： Chia L. Wang , John M. Davis , Bryan Lienke
IPC分类号： C08L75/04 , B05D3/12 , B05D1/36 , C08G18/32 , B05D1/28 , C09D5/16
CPC分类号： C08G18/7671 , C08G18/0842 , C08G18/2815 , C08G18/289 , C08G18/3215 , C08G18/3234 , C08G18/4816 , C08G18/4829 , C08G18/6685 , C08G18/721 , C08G18/8019 , C08G18/8067 , C08G2190/00
摘要： A two part construction sealant or adhesive is provided with the properties of non-sag, low modulus, high elongation, and good paint adhesion. The sealant or adhesive is prepared using at least one of a secondary amine or an acrylate monomer, and a diol, triol and/or tetrol having a nominal weight average molecular weight of between 1,000 and 6,000 in the base component of the formulation, and aromatic diisocyanate monomer or polyisocyanate and an isocyanate terminated prepolymer of aromatic diisocyanate or polyisocyanate and polyol in the activator component, the components of Part A to Part B mixed at a weight ratio of 5:1 to 1.8:1.
摘要翻译：提供两部分建筑密封剂或粘合剂，具有非凹陷，低模量，高伸长率和良好的涂料附着性的特性。密封剂或粘合剂使用仲胺或丙烯酸酯单体和在制剂的基础组分中具有1,000至6,000的标称重均分子量的二醇，三醇和/或四醇中的至少一种和芳族化合物二异氰酸酯单体或多异氰酸酯，以及活化剂组分中芳族二异氰酸酯或多异氰酸酯和多元醇的异氰酸酯封端预聚物，部分A至部分B的组分以5:1至1.8:1的重量比混合。

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