专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US06136990A Taxoid compound and method for producing the same 有权
标题翻译：紫杉烷类化合物及其制备方法
公开(公告)号：US06136990A
公开(公告)日：2000-10-24
申请号：US504788
申请日：2000-02-15
申请人： Tadakatsu Mandai , Hiroshi Okumoto , Katsuyoshi Nakanishi , Koji Hara , Katsuhiko Mikuni , Kozo Hara
发明人： Tadakatsu Mandai , Hiroshi Okumoto , Katsuyoshi Nakanishi , Koji Hara , Katsuhiko Mikuni , Kozo Hara
IPC分类号： C07D305/14 , C07D413/12 , C07D405/00 , C07D409/00
CPC分类号： C07D413/12 , C07D305/14
摘要： A taxoid compound represented by general formula (I) ##STR1## where the symbols R.sup.1, R.sup.2, R.sup.3, R.sup.4, Bz, and Ac have specified meanings. Also, a method for producing the taxoid derivative from a baccatin derivative having a .beta.-ketoester group at the 13-position by transesterification and a method for producing taxoid compound such as paclitaxel from the taxoid derivative under mild condition are disclosed.
摘要翻译：其中符号R1，R2，R3，R4，Bz和Ac具有特定含义的由通式（I）表示的紫杉烷类化合物。另外，公开了一种通过酯交换从具有β-酮酯基团的13位的浆果赤霉素衍生物制备紫杉烷衍生物的方法以及在温和条件下从紫杉烷衍生物制备紫杉醇类紫杉醇化合物的方法。

12. 发明授权

US5154521A Printer having ribbon mask for reducing interference with recording sheet 失效
标题翻译：打印机具有色带面罩，可减少与记录纸的干扰
公开(公告)号：US5154521A
公开(公告)日：1992-10-13
申请号：US700258
申请日：1991-05-15
申请人： Yoshiaki Tanaka , Kozo Hara , Kiyotaka Nihashi
发明人： Yoshiaki Tanaka , Kozo Hara , Kiyotaka Nihashi
IPC分类号： B41J35/26
CPC分类号： B41J35/26
摘要： In a printer having a platen, a print head disposed opposite to the platen, and a ribbon mask fixedly provided on the print head and having a masking plate provided with an aperture to expose only the front end of the print head to the platen, an ink ribbon is extended through a space between the platen and the print head, and the masking plate is disposed between the platen and the ink ribbon to shield a recording sheet wound round the platen from the ink ribbon. The aperture of the masking plate has inclined edges inclined to a direction perpendicular to the direction of movement of the print head so as to intersect a platen center obliquely. In case the side edge of a floating portion of the recording sheet is caught in the aperture of the masking plate while the print head is moved, the side edge slides along the inclined edge to escape from the aperture, so that the side edge is not caught in the aperture of the masking plate.
摘要翻译：在具有压板的打印机中，与压板相对设置的打印头和固定地设置在打印头上的色带掩模，并且具有设置有仅将打印头的前端暴露于压板的孔的掩模板，墨带延伸通过压板和打印头之间的空间，并且掩模板设置在压板和墨带之间，以将卷绕在压板上的记录纸从墨带上屏蔽。掩模板的孔径具有相对于与打印头的移动方向垂直的方向倾斜的倾斜边缘，以便倾斜地与压板中心相交。在打印头移动时记录纸的浮动部分的侧边缘被夹在掩模板的孔中的情况下，侧边缘沿着倾斜边缘滑动以从孔中逸出，使得侧边缘不卡在掩模板的孔中。

13. 发明授权

US6075132A Ursodeoxycholic acid derivatives and methods for producing them 失效
标题翻译：熊去氧胆酸衍生物及其制备方法
公开(公告)号：US6075132A
公开(公告)日：2000-06-13
申请号：US069990
申请日：1998-04-30
申请人： Tadakatsu Mandai , Hiroshi Okumoto , Katsuyoshi Nakanishi , Koji Hara , Katsuhiko Mikuni , Kozo Hara , Teruhiko Umetsu
发明人： Tadakatsu Mandai , Hiroshi Okumoto , Katsuyoshi Nakanishi , Koji Hara , Katsuhiko Mikuni , Kozo Hara , Teruhiko Umetsu
IPC分类号： C07J9/00 , C07J17/00 , C07J75/00
CPC分类号： C07J9/005 , C07J17/005
摘要： Disclosed are ursodeoxycholic acid derivatives having an increased solubility in water, and methods for producing the derivatives. To produce the derivatives, ursodeoxycholic acid is protected at its carboxyl group with a benzyl group, then reacted with tetrabenzyl-acetic acid-oxyglucoside of the following formula (1), and de-benzylated; or ursodeoxycholic acid is protected at its hydroxyl group with a t-butyldimethylsilyl group, then reacted with tetrabenzyl-2-hydroxyethyloxyglucoside of the following formula (2), and de-t-butyldimethylsilylated and de-benzylated. ##STR1##
摘要翻译：公开了在水中溶解度增加的熊去氧胆酸衍生物及其衍生物的制造方法。为了制备衍生物，熊氧胆酸在其羧基上用苄基保护，然后与下式（1）的四苄基 - 乙酸 - 氧葡萄糖苷反应，并脱苄基化; 或熊去氧胆酸在其羟基上用叔丁基二甲基甲硅烷基保护，然后与下式（2）的四苄基-2-羟基乙氧基葡萄糖苷和去叔丁基二甲基甲硅烷基化和脱苄基化反应。

14. 发明授权

US5854408A Process for acylating the 1-position of saccharides 失效
标题翻译：酰化1位糖的方法
公开(公告)号：US5854408A
公开(公告)日：1998-12-29
申请号：US868147
申请日：1997-06-03
申请人： Tadakatsu Mandai , Hiroshi Okumoto , Koji Hara , Katsuhiko Mikuni , Kozo Hara , Hiroki Hamada
发明人： Tadakatsu Mandai , Hiroshi Okumoto , Koji Hara , Katsuhiko Mikuni , Kozo Hara , Hiroki Hamada
IPC分类号： C07H1/00 , C07H15/04 , C07H15/18 , C07H3/02 , C07H3/04
CPC分类号： C07H15/18 , C07H15/04 , Y02P20/55
摘要： A sugar derivative wherein a hydroxy-carboxylic acid is combined to a position 1 of a sugar via ether linkage, and other hydroxyl groups are protected with a protective groups. A method of producing the sugar derivative, comprises allowing glycolic ester to react with a compound so as to combine said glycolic ester at the position 1 of the sugar skeleton, and then saponifying, said compound has on the position 1 any of hydroxyl group, halogen atom and sulfur atom with a substitutent group, and has other hydroxyl groups being protected with a protective groups.
摘要翻译：将羟基羧酸通过醚键与糖的位置1结合的糖衍生物和其它羟基用保护基保护。制备糖衍生物的方法包括使乙醇酸酯与化合物反应，以将所述乙醇酸酯在糖骨架的位置1上组合，然后皂化，所述化合物在1位上任何羟基，卤素具有取代基的原子和硫原子，并且其它羟基被保护基团保护。

15. 发明授权

US5767297A Taxoid derivative and method of producing thereof 失效
标题翻译：紫杉烷衍生物及其制备方法
公开(公告)号：US5767297A
公开(公告)日：1998-06-16
申请号：US868151
申请日：1997-06-03
申请人： Tadakatsu Mandai , Hiroshi Okumoto , Koji Hara , Katsuhiko Mikuni , Kozo Hara , Hiroki Hamada
发明人： Tadakatsu Mandai , Hiroshi Okumoto , Koji Hara , Katsuhiko Mikuni , Kozo Hara , Hiroki Hamada
IPC分类号： C07D305/14
CPC分类号： C07D305/14
摘要： A taxoid derivative wherein sugar is combined with any one of paclitaxel, docetaxel and 10-deacetyl-bacatin III via a spacer. A method of producing the taxoid derivative comprises protecting hydroxyl groups at specific position of paclitaxel or docetaxel by protective compound followed by reacting with tetrabenzyl acetyloxyglucoside, and then carrying out debenzyl and detriethylsilyl reactions. A method of producing the taxoid derivative comprises reacting paclitaxel or docetaxel with tetrabenzyl acetyloxyglucoside, and then carrying out debenzyl reaction.
摘要翻译：一种紫杉烷衍生物，其中糖通过间隔基与紫杉醇，多西他赛和10-脱乙酰基 - 条肽III中的任一种组合。制备紫杉烷衍生物的方法包括用保护性化合物保护紫杉醇或多西他赛特定位置的羟基，然后与四苄基乙酰氧基葡糖苷反应，然后进行脱苄基和脱乙基甲硅烷基反应。制备紫杉烷衍生物的方法包括使紫杉醇或多西紫杉醇与四苄基乙酰氧基葡糖苷反应，然后进行脱苄基反应。

16. 发明授权

US4944542A Support device 失效
标题翻译：支持设备
公开(公告)号：US4944542A
公开(公告)日：1990-07-31
申请号：US254183
申请日：1988-10-06
申请人： Mizuki Uchida , Kozo Hara
发明人： Mizuki Uchida , Kozo Hara
IPC分类号： B23Q7/10 , H01L21/677
CPC分类号： H01L21/67706 , B23Q7/103 , H01L21/67712 , H01L21/67781 , Y10S294/902 , Y10S294/907 , Y10S414/14
摘要： A support device of the present invention includes an expansible means attached to at least one of plural support systems for supporting an object. Even when the object has dimensional errors caused in its making process, therefore, the interval between the support systems which contact the object to be supported can be self- and micro-adjusted. This enables objects, different in shape, to be correctly positioned and supported.
摘要翻译：本发明的支撑装置包括附接到用于支撑物体的多个支撑系统中的至少一个的可扩展装置。因此，即使对象在其制造过程中产生尺寸误差，也可以自动调整与被支撑物接触的支撑体之间的间隔。这使得形状不同的对象能够被正确定位和支持。

17. 发明授权

US4860363A Loudspeaker system 失效
标题翻译：扬声器系统
公开(公告)号：US4860363A
公开(公告)日：1989-08-22
申请号：US171224
申请日：1988-03-18
申请人： Hitoshi Suzuki , Kozo Hara , Shiro Koga , Shigeru Morita
发明人： Hitoshi Suzuki , Kozo Hara , Shiro Koga , Shigeru Morita
IPC分类号： H04R1/32 , H04R5/02
CPC分类号： H04R5/02 , H04R1/323
摘要： The present invention includes a loudspeaker system in which sound radiation axes of two speakers in a single loudspeaker unit form an angle with respect to each other in a horizontal plane to increase the size of a listening area. The horizontal angle can be formed by orienting the sound axes of speakers in the loudspeaker unit at an angle in the range of 15 to 45 degrees from each other. The system also includes a phase adjustment system which adjusts the phase of the speakers in each loudspeaker unit so that the phase of the sound from each speaker in each loudspeaker unit is properly adjusted throughout the increased listening area to provide increased sound presence or spread.
摘要翻译：本发明包括扬声器系统，其中单个扬声器单元中的两个扬声器的声辐射轴在水平面中相对于彼此形成一角度以增加收听区域的尺寸。水平角度可以通过将扬声器单元中的扬声器的声轴以15至45度的角度定向来形成。该系统还包括相位调整系统，其调节每个扬声器单元中的扬声器的相位，使得在每个扬声器单元中的每个扬声器的声音的相位在整个增加的收听区域中被适当地调整以提供增加的声音存在或扩展。

18. 发明授权

US07030237B2 Method and equipment for continuous and selective inclusion separation 失效
公开(公告)号：US07030237B2
公开(公告)日：2006-04-18
申请号：US10009627
申请日：2000-12-21
申请人： Isamu Uemasu , Kozo Hara , Hideki Takahashi
发明人： Isamu Uemasu , Kozo Hara , Hideki Takahashi
IPC分类号： C08B37/16
CPC分类号： C07D215/06 , C07B63/00 , C07C7/152 , C07C17/395 , C07C201/16 , C07C2602/42 , C07C25/02 , C07C25/10 , C07C205/06 , C07C15/08 , C07C15/24 , C07C13/21 , C07C13/39
摘要： In a reaction system having at least two liquid-liquid interfaces between an organic phase of raw material containing a compound(s) to be separated and an aqueous phase of an aqueous solution of inclusion-complexing agent and between that aqueous phase and an organic phase(s) of extraction solvent(s), the compound(s) to be separated is entrapped into the aqueous phase through formation of an inclusion complex(es) of the inclusion-complexing agent with the compound(s), while the compound(s) is entrapped into the organic phase(s) of extraction solvent(s) through dissociation of said inclusion complex(es). The foregoing operation is performed using, for example, a squarish U-shaped tube or an H-shaped tube with bottom plates. Preferred examples of inclusion-complexing agent include highly water-soluble branched cyclodextrins.

19. 发明授权

US06410757B1 Baccatin derivatives and a process for producing the same 有权
标题翻译：浆果赤霉素衍生物及其制备方法
公开(公告)号：US06410757B1
公开(公告)日：2002-06-25
申请号：US09499393
申请日：2000-02-07
申请人： Tadakatsu Mandai , Hiroshi Okumoto , Katsuyoshi Nakanishi , Koji Hara , Katsuhiko Mikuni , Kozo Hara
发明人： Tadakatsu Mandai , Hiroshi Okumoto , Katsuyoshi Nakanishi , Koji Hara , Katsuhiko Mikuni , Kozo Hara
IPC分类号： C07D30514
CPC分类号： C07D305/14 , Y02P20/55
摘要： The object of the invention is to develop baccatin derivatives useful for preparing taxoid compounds such as paclitaxel and a process for the producing the same. The invention provides baccatin derivatives represented by the general formula (I) as well as a process for producing baccatin derivatives represented by the general formula (I) above, which comprises allowing a baccatin represented by the general formula (II) to react with a &bgr;-ketoester in the absence of a catalyst or in the presence of a tin compound or an amine base, preferably under reduced pressure.
摘要翻译：本发明的目的是开发可用于制备紫杉醇类紫杉醇类化合物的浆果赤霉素衍生物及其制备方法。本发明提供由通式（I）表示的浆果赤霉素衍生物以及由上述通式（I）表示的浆果赤霉素衍生物的制备方法，其包括使由通式（II）表示的浆果赤霉素与β - 在不存在催化剂的情况下或在锡化合物或胺碱的存在下，优选在减压下进行。

20. 发明授权

US06264748B1 Substrate processing apparatus 有权
标题翻译：基板加工装置
公开(公告)号：US06264748B1
公开(公告)日：2001-07-24
申请号：US09130104
申请日：1998-08-06
申请人： Yasuyuki Kuriki , Hideyuki Takamori , Kozo Hara
发明人： Yasuyuki Kuriki , Hideyuki Takamori , Kozo Hara
IPC分类号： C23C1600
CPC分类号： H01L21/67173 , C23C16/54 , H01L21/67742
摘要： A substrate processing apparatus comprises a processing section having a plurality of process units for applying a series of processes including a resist coating to a processing substrate, a developing process to an exposed substrate, and an etching to the developed processing substrate, a main transferring mechanism, moving along a transferring path, for transferring/receiving the processing substrate to/from the respective process units, and a loading/unloading portion having a transferring/receiving mechanism for transferring/receiving the processing substrate to/from the main transferring apparatus, wherein these process units, the transferring path, and the loading/unloading portion are integrally provided.
摘要翻译：一种基板处理装置，包括具有多个处理单元的处理单元，所述处理单元用于向处理基板施加包括抗蚀剂涂层的一系列处理，对曝光基板的显影处理以及对显影处理基板的蚀刻，主转印机构沿着传送路径移动，用于向/从各个处理单元传送/接收处理基板;以及装载/卸载部分，具有用于向/从主传送装置传送/接收处理基板的传送/接收机构，其中这些处理单元，传送路径和装载/卸载部分是一体的。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式