专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US08121694B2 Therapy control based on a patient movement state 有权
标题翻译：基于患者运动状态的治疗控制
公开(公告)号：US08121694B2
公开(公告)日：2012-02-21
申请号：US12237799
申请日：2008-09-25
申请人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
发明人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
IPC分类号： A61N1/18
CPC分类号： A61B5/04014 , A61B5/0006 , A61B5/4082 , A61B5/6814 , A61N1/36003 , A61N1/36014 , A61N1/36025 , A61N1/36067 , A61N1/36082
摘要： A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.
摘要翻译：基于诸如脑电图（EEG）信号的脑信号检测患者的运动状态。在一些示例中，可以检测指示患者的预期运动的患者的脑的背侧前额叶皮层内的脑信号，以便检测运动状态。运动状态可以包括指示患者打算启动运动，启动运动，尝试启动运动或实际运动的脑状态。在一些示例中，在检测到运动状态时，将运动障碍治疗递送给患者。在一些示例中，在检测到患者不再处于运动状态或患者已成功启动运动时，治疗递送被停用。此外，在一些示例中，可以基于来自运动传感器的信号来确认基于脑信号检测到的运动状态。

12. 发明申请

US20110301575A1 IMPLANTABLE MEDICAL PUMP WITH PRESSURE SENSOR 有权
标题翻译：带压力传感器的可植入医用泵
公开(公告)号：US20110301575A1
公开(公告)日：2011-12-08
申请号：US12793457
申请日：2010-06-03
申请人： Keith A. Miesel , James M. Haase , Chris J. Paidosh , Darren A. Janzig , Timothy J. Denison
发明人： Keith A. Miesel , James M. Haase , Chris J. Paidosh , Darren A. Janzig , Timothy J. Denison
IPC分类号： A61M5/14 , G01L9/12
CPC分类号： A61M5/14276 , A61M39/0208 , A61M2205/3317 , A61M2205/3331 , G01L9/0072 , G01L15/00 , G01L19/0023 , G01L19/0069 , G01L19/086 , G01L19/143 , G01L19/148 , G01L19/149
摘要： The disclosure is directed to a pressure sensor of an implantable medical device. The pressure sensor may utilize detect fluid pressure based on a changing capacitance between two capacitive elements. The pressure sensor may define at least a portion of a fluid enclosure of the IMD. In one example, the pressure sensor has a self-aligning housing shape that occludes an opening in the pump bulkhead of the IMD. An operative surface of the pressure and the portion of the fluid enclosure may be formed of a corrosion resistant and/or biocompatible material. A first capacitive element of the pressure sensor may be a metal alloy diaphragm that deflects in response to external fluid pressure. A second capacitive element of the pressure sensor may be a metal coating on a rigid insulator sealed from the fluid by the diaphragm and a housing of the sensor.
摘要翻译：本公开涉及可植入医疗装置的压力传感器。压力传感器可以利用基于两个电容元件之间的变化的电容的检测流体压力。压力传感器可以限定IMD的流体外壳的至少一部分。在一个示例中，压力传感器具有封闭IMD的泵舱壁中的开口的自对准壳体形状。压力的操作表面和流体外壳的一部分可以由耐腐蚀和/或生物相容的材料形成。压力传感器的第一电容元件可以是响应于外部流体压力而偏转的金属合金膜片。压力传感器的第二电容元件可以是通过隔膜和传感器的壳体与流体密封的刚性绝缘体上的金属涂层。

13. 发明授权

US10369353B2 Seizure disorder evaluation based on intracranial pressure and patient motion 有权
公开(公告)号：US10369353B2
公开(公告)日：2019-08-06
申请号：US12359037
申请日：2009-01-23
申请人： Jonathon E. Giftakis , Nina M. Graves , Jonathan C. Werder , Eric J. Panken , Timothy J. Denison , Keith A. Miesel , Michele H. Herzog
发明人： Jonathon E. Giftakis , Nina M. Graves , Jonathan C. Werder , Eric J. Panken , Timothy J. Denison , Keith A. Miesel , Michele H. Herzog
IPC分类号： A61B5/03 , A61N1/05 , A61B5/00 , A61N1/36
摘要： Intracranial pressure of a patient may be monitored in order to evaluate a seizure disorder. In some examples, trends in the intracranial pressure over time may be monitored, e.g., to detect changes to the patient's condition. In addition, in some examples, a seizure metric may be generated for a detected seizure based on sensed intracranial pressures. The seizure metric may indicate, for example, an average, median, or highest relative intracranial pressure value observed during a seizure, a percent change from a baseline value during the seizure, or the time for the intracranial pressure to return to a baseline state after the occurrence of a seizure. In addition to or instead of intracranial pressure, patient motion or posture may be monitored in order to assess the patient's seizure disorder. For example, a seizure type or severity may be determined based on patient motion sensed during a seizure.

14. 发明授权

US09327117B2 Bladder sensing using impedance and posture 有权
标题翻译：膀胱感应使用阻抗和姿势
公开(公告)号：US09327117B2
公开(公告)日：2016-05-03
申请号：US13264023
申请日：2010-04-20
申请人： Timothy J. Denison , Keith A. Miesel
发明人： Timothy J. Denison , Keith A. Miesel
IPC分类号： A61B5/04 , A61B5/05 , A61B5/00 , A61N1/36 , A61B5/053 , A61B5/11 , A61B5/20
CPC分类号： A61N1/36007 , A61B5/053 , A61B5/1116 , A61B5/204 , A61B5/686 , A61B5/6883 , A61B5/7203 , A61B2560/0462 , A61B2562/0219
摘要： This disclosure provides techniques for bladder sensing. In accordance with the techniques described in this disclosure, a device may measure the impedance of a bladder, determine the posture of a patient, and determine a status of the bladder based on the impedance and posture.
摘要翻译：本公开提供了用于膀胱感测的技术。根据本公开中描述的技术，装置可以测量膀胱的阻抗，确定患者的姿势，并且基于阻抗和姿势来确定膀胱的状态。

15. 发明授权

US08397578B2 Capacitive pressure sensor assembly 有权
标题翻译：电容式压力传感器组件
公开(公告)号：US08397578B2
公开(公告)日：2013-03-19
申请号：US12793459
申请日：2010-06-03
申请人： Keith A. Miesel , James M. Haase , Chris J. Paidosh , Darren A. Janzig , Timothy J. Denison
发明人： Keith A. Miesel , James M. Haase , Chris J. Paidosh , Darren A. Janzig , Timothy J. Denison
IPC分类号： G01L9/12 , A61M5/14
CPC分类号： G01L9/0072 , G01L19/142 , G01L19/143 , G01L19/147 , H01L2224/48472 , Y10T29/49002 , Y10T29/53265
摘要： The disclosure is directed to a capacitive pressure sensor, and the assembly of a capacitive pressure sensor, that may be used within an implantable medical pump. In one example, a housing ferrule that encloses one capacitive plate and includes at least one protrusion for attaching a support structure of the capacitive plate. The at least one protrusion defines a smaller inner diameter as a reference point for securing the support structure while the ferrule provides a larger inner diameter to allow the support structure to tilt inside the ferrule to orient the capacitive plate into a desired plane. Despite manufacturing irregularities, the capacitive plate can be mounted in the desired plane parallel to another capacitive plate, a diaphragm, mounted to an edge of the ferrule. In another example, an assembly tool provides a stage to orient the capacitive plate and support structure within the ferrule at a desired depth.
摘要翻译：本公开涉及电容式压力传感器以及可在可植入医疗泵内使用的电容式压力传感器的组件。在一个示例中，壳体套圈包围一个电容板并且包括用于附接电容板的支撑结构的至少一个突起。所述至少一个突出部限定较小的内径作为用于固定支撑结构的参考点，同时套圈提供更大的内径以允许支撑结构在套圈内部倾斜以将电容板定向到期望的平面。尽管制造不规则，但是电容板可以安装在平行于另一个电容板的所需平面中，该电容板安装在套圈的边缘上。在另一示例中，组装工具提供了将电容板和支撑结构定位在套圈内的阶段，以期望的深度。

16. 发明申请

US20110296925A1 CAPACITIVE PRESSURE SENSOR ASSEMBLY 有权
标题翻译：电容式压力传感器总成
公开(公告)号：US20110296925A1
公开(公告)日：2011-12-08
申请号：US12793459
申请日：2010-06-03
申请人： Keith A. Miesel , James M. Haase , Chris J. Paidosh , Darren A. Janzig , Timothy J. Denison
发明人： Keith A. Miesel , James M. Haase , Chris J. Paidosh , Darren A. Janzig , Timothy J. Denison
IPC分类号： G01L9/12 , H05K13/04
CPC分类号： G01L9/0072 , G01L19/142 , G01L19/143 , G01L19/147 , H01L2224/48472 , Y10T29/49002 , Y10T29/53265
摘要： The disclosure is directed to a capacitive pressure sensor, and the assembly of a capacitive pressure sensor, that may be used within an implantable medical pump. In one example, a housing ferrule that encloses one capacitive plate and includes at least one protrusion for attaching a support structure of the capacitive plate. The at least one protrusion defines a smaller inner diameter as a reference point for securing the support structure while the ferrule provides a larger inner diameter to allow the support structure to tilt inside the ferrule to orient the capacitive plate into a desired plane. Despite manufacturing irregularities, the capacitive plate can be mounted in the desired plane parallel to another capacitive plate, a diaphragm, mounted to an edge of the ferrule. In another example, an assembly tool provides a stage to orient the capacitive plate and support structure within the ferrule at a desired depth.
摘要翻译：本公开涉及电容式压力传感器以及可在可植入医疗泵内使用的电容式压力传感器的组件。在一个示例中，壳体套圈包围一个电容板并且包括用于附接电容板的支撑结构的至少一个突起。所述至少一个突出部限定较小的内径作为用于固定支撑结构的参考点，同时套圈提供更大的内径以允许支撑结构在套圈内部倾斜以将电容板定向到期望的平面。尽管制造不规则，但是电容板可以安装在平行于另一个电容板的所需平面中，该电容板安装在套圈的边缘上。在另一示例中，组装工具提供了将电容板和支撑结构定位在套圈内的阶段，以期望的深度。

17. 发明授权

US09737657B2 Implantable medical pump with pressure sensor 有权
公开(公告)号：US09737657B2
公开(公告)日：2017-08-22
申请号：US12793457
申请日：2010-06-03
申请人： Keith A. Miesel , James M. Haase , Chris J. Paidosh , Darren A. Janzig , Timothy J. Denison
发明人： Keith A. Miesel , James M. Haase , Chris J. Paidosh , Darren A. Janzig , Timothy J. Denison
IPC分类号： A61M5/14 , G01L9/12 , A61M5/142 , A61M39/02 , G01L9/00 , G01L15/00 , G01L19/00 , G01L19/08 , G01L19/14
CPC分类号： A61M5/14276 , A61M39/0208 , A61M2205/3317 , A61M2205/3331 , G01L9/0072 , G01L15/00 , G01L19/0023 , G01L19/0069 , G01L19/086 , G01L19/143 , G01L19/148 , G01L19/149
摘要： The disclosure is directed to a pressure sensor of an implantable medical device. The pressure sensor may utilize detect fluid pressure based on a changing capacitance between two capacitive elements. The pressure sensor may define at least a portion of a fluid enclosure of the IMD. In one example, the pressure sensor has a self-aligning housing shape that occludes an opening in the pump bulkhead of the IMD. An operative surface of the pressure and the portion of the fluid enclosure may be formed of a corrosion resistant and/or biocompatible material. A first capacitive element of the pressure sensor may be a metal alloy diaphragm that deflects in response to external fluid pressure. A second capacitive element of the pressure sensor may be a metal coating on a rigid insulator sealed from the fluid by the diaphragm and a housing of the sensor.

18. 发明申请

US20100121214A1 SEIZURE DISORDER EVALUATION BASED ON INTRACRANIAL PRESSURE AND PATIENT MOTION 审中-公开
标题翻译：基于内分泌压力和患者运动的癫痫病症评估
公开(公告)号：US20100121214A1
公开(公告)日：2010-05-13
申请号：US12359055
申请日：2009-01-23
申请人： Jonathon E. Giftakis , Nina M. Graves , Jonathan C. Werder , Eric J. Panken , Timothy J. Denison , Keith A. Miesel , Michele H. Herzog
发明人： Jonathon E. Giftakis , Nina M. Graves , Jonathan C. Werder , Eric J. Panken , Timothy J. Denison , Keith A. Miesel , Michele H. Herzog
IPC分类号： A61B5/0476 , A61B5/03 , A61B5/11 , A61B5/053
CPC分类号： A61N1/0534 , A61B5/031 , A61B5/4094 , A61N1/36082
摘要： Intracranial pressure of a patient may be monitored in order to evaluate a seizure disorder. In some examples, trends in the intracranial pressure over time may be monitored, e.g., to detect changes to the patient's condition. In addition, in some examples, a seizure metric may be generated for a detected seizure based on sensed intracranial pressures. The seizure metric may indicate, for example, an average, median, or highest relative intracranial pressure value observed during a seizure, a percent change from a baseline value during the seizure, or the time for the intracranial pressure to return to a baseline state after the occurrence of a seizure. In addition to or instead of intracranial pressure, patient motion or posture may be monitored in order to assess the patient's seizure disorder. For example, a seizure type or severity may be determined based on patient motion sensed during a seizure.
摘要翻译：可以监测患者的颅内压，以评估癫痫发作障碍。在一些示例中，可以监测颅内压力随时间的趋势，例如以检测患者状况的变化。此外，在一些示例中，可以基于感测的颅内压力产生针对检测到的发作的发作量度。癫痫发作度数可以表示例如在癫痫发作期间观察到的平均值，中位数或最高相对颅内压值，在癫痫发作期间从基线值变化的百分比，或颅内压力回到基线状态的时间发生癫痫发作。除了或代替颅内压之外，可以监测患者的运动或姿势以评估患者的癫痫发作障碍。例如，可以基于在癫痫发作期间感测到的患者运动来确定癫痫发作类型或严重程度。

19. 发明申请

US20080081958A1 Implantable medical device with sensor self-test feature 审中-公开
标题翻译：具有传感器自检功能的植入式医疗设备
公开(公告)号：US20080081958A1
公开(公告)日：2008-04-03
申请号：US11789438
申请日：2007-04-24
申请人： Timothy J. Denison , Brian B. Lee , Keith A. Miesel , Eric J. Panken
发明人： Timothy J. Denison , Brian B. Lee , Keith A. Miesel , Eric J. Panken
IPC分类号： A61B5/00
CPC分类号： A61N1/3706 , A61B2560/0276 , A61N1/36535 , A61N1/36542 , A61N1/3702
摘要： An implantable medical device (IMD) applies a sensor self-test when a sensing device generates a sensor signal indicating an event, or when the sensor is used to validate an event detected by another device. The event may be based on a sensed condition that triggers an operational adjustment, such as a therapy or diagnostic adjustment within the IMD. A sensor self-test verifies that an implantable sensing device is functional, and can be performed with or without activating the sensor. Activating the sensor may involve, application of an electrical input signal that causes the sensor to generate an output signal. Alternatively, the sensor self-test may be performed without activating the sensor by analyzing the continuity of a signal path between the sensor and sensor interface circuitry. In either case, a sensor self-test verifies proper operation so that operational adjustments can be made with greater confidence.
摘要翻译：当感测装置产生指示事件的传感器信号时，或者当传感器用于验证另一个设备检测到的事件时，可植入医疗设备（IMD）应用传感器自检。事件可以基于触发操作调整的感测条件，例如IMD内的治疗或诊断调整。传感器自检可以验证可植入的感测装置是否起作用，并且可以在启动或不启动传感器的情况下执行。激活传感器可能涉及施加导致传感器产生输出信号的电输入信号。或者，可以通过分析传感器和传感器接口电路之间的信号路径的连续性而不激活传感器来执行传感器自检。在任一种情况下，传感器自检将验证正确的操作，以便可以更有信心地进行操作调整。

20. 发明授权

US08554325B2 Therapy control based on a patient movement state 有权
标题翻译：基于患者运动状态的治疗控制
公开(公告)号：US08554325B2
公开(公告)日：2013-10-08
申请号：US13345397
申请日：2012-01-06
申请人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
发明人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
IPC分类号： A61N1/18
CPC分类号： A61B5/04014 , A61B5/0006 , A61B5/4082 , A61B5/6814 , A61N1/36003 , A61N1/36014 , A61N1/36025 , A61N1/36067 , A61N1/36082
摘要： A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.
摘要翻译：基于诸如脑电图（EEG）信号的脑信号检测患者的运动状态。在一些示例中，可以检测指示患者的预期运动的患者的脑的背侧前额叶皮层内的脑信号，以便检测运动状态。运动状态可以包括指示患者打算启动运动，启动运动，尝试启动运动或实际运动的脑状态。在一些示例中，在检测到运动状态时，将运动障碍治疗递送给患者。在一些示例中，在检测到患者不再处于运动状态或患者已成功启动运动时，治疗递送被停用。此外，在一些示例中，可以基于来自运动传感器的信号来确认基于脑信号检测到的运动状态。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式