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151. 发明申请

US20060286205A1 Biomass hydrolysate and uses and production thereof 失效
标题翻译：生物质水解产物及其用途及生产
公开(公告)号：US20060286205A1
公开(公告)日：2006-12-21
申请号：US11433752
申请日：2006-05-12
申请人： Jaouad Fichtali , Micah Needham , Henry Linsert
发明人： Jaouad Fichtali , Micah Needham , Henry Linsert
IPC分类号： A61K47/00 , A23J3/34 , C12P1/00
CPC分类号： C12P1/00 , A23J3/347 , A23L33/12 , A23L33/135 , A23L33/18 , A23V2002/00 , A61K8/361 , A61K8/97 , A61Q19/00 , C12P7/6427 , A23V2250/1882
摘要： The present invention includes a palatable, stable composition comprising a biomass hydrolysate emulsion for incorporation, into, or used as, nutritional products, cosmetic products or pharmaceutical products. Preferred sources for biomass are microbial sources, plant sources and animal sources. The present invention also provides methods for making such compositions, specifically, a method for producing a product comprising a nutrient, particularly a long chain polyunsaturated fatty acid, comprising hydrolyzing a biomass comprising the nutrient and emulsifying the hydrolyzed biomass. Such compositions and methods are useful, for example, for increasing intake of nutrients such as omega-3 long chain polyunsaturated fatty acids having 18 or more carbons.
摘要翻译：本发明包括一种可口的稳定的组合物，其包含用于掺入或用作营养产品，化妆品或药物产品的生物质水解产物乳液。生物质的优选来源是微生物来源，植物来源和动物来源。本发明还提供了制备这种组合物的方法，具体地说，涉及生产包含营养素，特别是长链多不饱和脂肪酸的产品的方法，包括水解包含营养物质的生物质并乳化水解的生物质。这样的组合物和方法可用于例如增加摄入营养物质，例如具有18个或更多个碳的ω-3长链多不饱和脂肪酸。

152. 发明申请

US20060241088A1 Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same 失效
标题翻译：来自长链多不饱和脂肪酸的牛痘素及其制备和使用方法
公开(公告)号：US20060241088A1
公开(公告)日：2006-10-26
申请号：US11284790
申请日：2005-11-21
申请人： Linda Arterburn , William Barclay , Bindi Dangi , James Flatt , Jung Lee , Mary Elswyk
发明人： Linda Arterburn , William Barclay , Bindi Dangi , James Flatt , Jung Lee , Mary Elswyk
IPC分类号： A61K31/60 , A61K31/22 , C07C69/02
CPC分类号： C12P7/6472 , C07C59/42 , C07D303/38 , C12P7/6427
摘要： Disclosed are novel oxylipins, referred to herein as docosanoids, that are derived from C22 polyunsaturated fatty acids, and method of making and using such oxylipins. Also disclosed is the use of docosapentaenoic acid (C22:5n-6) (DPAn-6), docosapentaenoic acid (C22:5n-3) (DPAn-3), and docosatetraenoic acid (DTAn-6: C22:4n-6) as substrates for the production of novel oxylipins, and to the oxylipins produced thereby. Also disclosed is the use of DPAn-6, DPAn-3, DTAn-6, and/or the oxylipins derived therefrom, and/or novel docosanoids derived from the structures of C22 fatty acids, in therapeutic and nutritional or cosmetic applications, and particularly as anti-inflammatory or anti-neurodegenerative compounds. The invention also relates to novel ways of producing long chain polyunsaturated acid (LCPUFA)-rich oils and compositions that contain enhanced and effective amounts of LCPUFA-derived oxylipins, and particularly, docosanoids.
摘要翻译：公开了衍生自C22多不饱和脂肪酸的新型oxylipin，本文称为多糖类，以及制备和使用这种oxylipin的方法。还公开了二十二碳五烯酸（C22：5n-6）（DPAn-6），二十二碳五烯酸（C22：5n-3）（DPAn-3）和二十二碳四烯酸（DTAn-6：C22：4n-6）作为生产新型oxylipins的底物，以及由此产生的oxylipin。还公开了在治疗和营养或化妆品应用中使用DPAn-6，DPAn-3，DTAn-6和/或衍生自其的oxylipin，和/或衍生自C22脂肪酸结构的新型二十二烷酸，特别是作为抗炎或抗神经变性化合物。本发明还涉及生产长链多不饱和酸（LCPUFA）的油和组合物的新方法，其含有增强和有效量的LCPUFA衍生的草甘膦脂类，尤其是二十二烷酸。

153. 发明授权

US07005280B2 Method of producing lipids by growing microorganisms of the order thraustochytriales 失效
标题翻译：通过生长次级破囊壶菌的微生物生产脂质的方法
公开(公告)号：US07005280B2
公开(公告)日：2006-02-28
申请号：US10856905
申请日：2004-05-27
申请人： William R. Barclay
发明人： William R. Barclay
IPC分类号： C12N1/00 , C12N1/14 , C12P1/00 , C12P7/64
CPC分类号： A23K40/25 , A23C9/20 , A23K10/16 , A23K10/30 , A23K20/158 , A23K40/20 , A23K40/35 , A23K50/00 , A23K50/10 , A23K50/75 , A23K50/80 , A23L5/00 , A23L11/07 , A23L13/00 , A23L13/43 , A23L13/50 , A23L15/20 , A23L17/00 , A23L17/40 , A23L17/65 , A23L19/09 , A23L25/30 , A23L29/065 , A23L31/00 , A23L33/12 , A61K31/20 , A61K31/202 , C11B1/10 , C12N1/14 , C12P7/6463 , C12P7/6472 , Y02A40/818 , Y10S435/911 , Y10S435/946
摘要： Disclosed is a process for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a preferred embodiment of the present invention, the process produces microflora having a cell aggregate size useful for the production of food products for use in aquaculture. Further disclosed is a food product which includes Thraustochytrium, Schizochytrium, and mixtures thereof, and a component selected from flaxseed, rapeseed, soybean and avocado meal. Such a food product includes a balance of long chain and short chain omega-3 highly unsaturated fatty acids. In an embodiment, lipids are produced by growing microorganisms of the order Thraustochytriales in a medium and extracting the lipids.
摘要翻译：本发明公开了一种生长微囊藻毒裂症，裂殖壶菌及其混合物的方法，其包括在含有非氯化钠的钠盐，特别是硫酸钠的发酵培养基中生长微生物群落。在本发明的优选实施方案中，该方法产生具有可用于生产用于水产养殖的食品的细胞聚集体尺寸的微生物群落。还公开了一种食品，其包括破囊壶菌，裂殖壶菌及其混合物，以及选自亚麻籽，油菜籽，大豆和鳄梨粉的成分。这种食品包括长链和短链ω-3高度不饱和脂肪酸的平衡。在一个实施方案中，脂质通过在培养基中培养Thraustochytriales级微生物并提取脂质而产生。

154. 发明授权

US6027900A Methods and tools for transformation of eukaryotic algae 有权
标题翻译：用于转化真核藻类的方法和工具
公开(公告)号：US6027900A
公开(公告)日：2000-02-22
申请号：US155972
申请日：1998-10-09
申请人： F. C. Thomas Allnutt , David J. Kyle , Arthur R. Grossman , Kirk R. Apt
发明人： F. C. Thomas Allnutt , David J. Kyle , Arthur R. Grossman , Kirk R. Apt
IPC分类号： C12N15/65 , C12N15/79 , C12Q1/68
CPC分类号： C12N15/79 , C12N15/65
摘要： Genetic fusions for use in genetic engineering of eukaryotic algae employ a promoter from a light harvesting protein fused to a protein of interest. The fusions can be introduced and selected using an antibiotic resistance determinant. One gene useful for such selection is the sh ble gene encoding a bleomycin binding protein.
摘要翻译： PCT No.PCT / US97 / 06021 Sec。 371日期：1998年10月9日 102（e）日期1998年10月9日PCT 1997年4月11日PCT PCT。 WO97 / 39106 PCT公开号日期1997年10月23日用于真核藻类遗传工程的遗传融合使用与感兴趣的蛋白质融合的光收获蛋白质的启动子。可以使用抗生素抗性决定簇引入和选择融合体。用于这种选择的一个基因是编码博来霉素结合蛋白的sh ble基因。

155. 发明授权

US5327901A Apparatus for collecting and storing human breath samples 失效
标题翻译：用于收集和储存人类呼吸样本的装置
公开(公告)号：US5327901A
公开(公告)日：1994-07-12
申请号：US52621
申请日：1993-04-27
申请人： Jacques J. Delente
发明人： Jacques J. Delente
IPC分类号： A61B5/08 , A61B5/083 , A61B5/097
CPC分类号： A61B5/097
摘要： A simplified, user-friendly method and apparatus for producing and collecting a human breath sample, and particularly alveolar air, for analysis of the constituent components thereof. The invention includes an elongated, hollow container and a breath delivery device for directing a subject's breath into the container. Closure means are provided for accommodating the insertion of the breath delivery device into the container and for substantially sealing the container. In one preferred embodiment, the closure means includes a flexible sealing element which allows the insertion and withdrawal of the breath delivery device and which forms a light interim seal at the opening of the hollow container while the opening is being positively sealed by the user. The volume of the container is small in comparison to the normal human breath which has the effect of purging the container of the initial breath portion and leaving primarily only the alveolar air.
摘要翻译：用于生产和收集人类呼吸样本，特别是肺泡空气的简化的，用户友好的方法和装置，用于分析其组成成分。本发明包括细长的中空容器和用于将受试者的呼吸引导到容器中的呼吸输送装置。提供闭合装置用于容纳将呼吸输送装置插入容器中并用于基本上密封容器。在一个优选实施例中，闭合装置包括柔性密封元件，该柔性密封元件允许呼吸输送装置的插入和抽出，并且在中空容器的开口处形成光中间密封，同时开口被用户牢固地密封。与正常人呼吸相比，容器的体积小，其具有吹扫初始呼吸部分的容器并且仅主要留下肺泡空气的效果。

156. 发明申请

US20120178135A1 ENHANCED PRODUCTION OF LIPIDS CONTAINING POLYENOIC FATTY ACIDS BY VERY HIGH DENSITY CULTURES OF EUKARYOTIC MICROBES IN FERMENTORS 有权
标题翻译：通过非常高密度的文化产品，增加包含多烯酸脂肪酸的脂肪的生产
公开(公告)号：US20120178135A1
公开(公告)日：2012-07-12
申请号：US13342623
申请日：2012-01-03
申请人： Richard B. Bailey , Don DiMasi , Jon M. Hansen , Peter J. Mirrasoul , Craig M. Ruecker , George T. Veeder, III , Tatsuo Kaneko , William R. Barclay
发明人： Richard B. Bailey , Don DiMasi , Jon M. Hansen , Peter J. Mirrasoul , Craig M. Ruecker , George T. Veeder, III , Tatsuo Kaneko , William R. Barclay
IPC分类号： C12P7/64
CPC分类号： A23K50/80 , A23D9/00 , A23K20/158 , A23L29/065 , A23V2002/00 , C11B1/10 , C12N1/00 , C12N1/12 , C12P7/6409 , C12P7/6427 , C12P7/6472 , Y10S435/911
摘要： The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
摘要翻译：本发明提供了一种生长真核微生物的方法，其能够产生脂质，特别是含有多烯脂肪酸的脂质。本发明还提供了一种生产真核微生物脂质的方法。

157. 发明授权

US08216812B2 Enhanced production of lipids containing polyenoic fatty acid by very high density cultures of eukaryotic microbes in fermentors 有权
公开(公告)号：US08216812B2
公开(公告)日：2012-07-10
申请号：US11745490
申请日：2007-05-08
申请人： Richard B. Bailey , Don DiMasi , John M. Hansen , Peter J. Mirrasoul , Craig M. Ruecker , George T. Veeder, III , Tatsuo Kaneko , William R. Barclay
发明人： Richard B. Bailey , Don DiMasi , John M. Hansen , Peter J. Mirrasoul , Craig M. Ruecker , George T. Veeder, III , Tatsuo Kaneko , William R. Barclay
IPC分类号： C12P7/64 , C12N1/14
CPC分类号： A23K50/80 , A23D9/00 , A23K20/158 , A23L29/065 , A23V2002/00 , C11B1/10 , C12N1/00 , C12N1/12 , C12P7/6409 , C12P7/6427 , C12P7/6472 , Y10S435/911
摘要： The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.

158. 发明授权

US08048652B2 Biomass hydrolysate and uses and production thereof 失效
标题翻译：生物质水解产物及其用途及生产
公开(公告)号：US08048652B2
公开(公告)日：2011-11-01
申请号：US11433752
申请日：2006-05-12
申请人： Jaouad Fichtali , Micah Hazzy Needham , Henry Linsert, Jr.
发明人： Jaouad Fichtali , Micah Hazzy Needham , Henry Linsert, Jr.
IPC分类号： C12P7/64
CPC分类号： C12P1/00 , A23J3/347 , A23L33/12 , A23L33/135 , A23L33/18 , A23V2002/00 , A61K8/361 , A61K8/97 , A61Q19/00 , C12P7/6427 , A23V2250/1882
摘要： The present invention includes a palatable, stable composition comprising a biomass hydrolysate emulsion for incorporation, into, or used as, nutritional products, cosmetic products or pharmaceutical products. Preferred sources for biomass are microbial sources, plant sources and animal sources. The present invention also provides methods for making such compositions, specifically, a method for producing a product comprising a nutrient, particularly a long chain polyunsaturated fatty acid, comprising hydrolyzing a biomass comprising the nutrient and emulsifying the hydrolyzed biomass. Such compositions and methods are useful, for example, for increasing intake of nutrients such as omega-3 long chain polyunsaturated fatty acids having 18 or more carbons.
摘要翻译：本发明包括一种可口的稳定的组合物，其包含用于掺入或用作营养产品，化妆品或药物产品的生物质水解产物乳液。生物质的优选来源是微生物来源，植物来源和动物来源。本发明还提供了制备这种组合物的方法，具体地说，涉及生产包含营养素，特别是长链多不饱和脂肪酸的产品的方法，包括水解包含营养物质的生物质并乳化水解的生物质。这样的组合物和方法可用于例如增加摄入营养物质，例如具有18个或更多个碳的ω-3长链多不饱和脂肪酸。

159. 发明授权

US08039030B2 Microwaveable popcorn and methods of making 有权
标题翻译：微波爆米花和制作方法
公开(公告)号：US08039030B2
公开(公告)日：2011-10-18
申请号：US11428296
申请日：2006-06-30
申请人： Jesus Ruben Abril , Thayne Fort
发明人： Jesus Ruben Abril , Thayne Fort
IPC分类号： A23L1/36
CPC分类号： C11B5/0092 , A23D9/00 , A23L7/174 , A23L7/183 , A23L29/04 , A23L33/12 , A23V2002/00 , Y10S426/808 , A23V2250/1882
摘要： Microwaveable popcorn compositions, products and methods of making the same are disclosed. The composition includes unpopped popcorn kernels, an oil comprising at least one omega-3 LC PUFA, and an oil that is solid at about 20° C. The an oil comprising at least one omega-3 LC PUFA can include a microbial oil prepared by extraction with isopropanol and water in the absence of winterization.
摘要翻译：公开了微波爆米花组合物，其制备方法及其制备方法。该组合物包括不受欢迎的爆米花仁，包含至少一种ω-3 LC PUFA的油和在约20℃下为固体的油。包含至少一种ω-3 LC PUFA的油可以包括由在不加冬季时用异丙醇和水进行萃取。

160. 发明申请

US20110206741A1 DHA Triglyceride Emulsions 审中-公开
标题翻译： DHA甘油三酯乳液
公开(公告)号：US20110206741A1
公开(公告)日：2011-08-25
申请号：US13031175
申请日：2011-02-18
申请人： Jung LEE , Bernard A. Mikrut , Xuejun Tang
发明人： Jung LEE , Bernard A. Mikrut , Xuejun Tang
IPC分类号： A61K9/107 , A61K31/22 , A61P9/04 , A61P1/16 , A61P19/02 , A61P9/10
CPC分类号： A61K9/0019 , A61K9/107
摘要： The present invention is directed to an emulsion comprising an emulsifier, an isotonic agent and a docosahexaenoic acid triglyceride (DHA-TG) wherein the emulsion is substantially free of eicosapentaenoic acid (EPA) and is suitable for parenteral administration.
摘要翻译：本发明涉及包含乳化剂，等渗剂和二十二碳六烯酸甘油三酸酯（DHA-TG）的乳液，其中所述乳液基本上不含二十碳五烯酸（EPA），并且适用于肠胃外给药。

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