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    • 116. 发明授权
    • Treatment of neurons with HGF
    • 用HGF处理神经元
    • US06699837B2
    • 2004-03-02
    • US08605221
    • 1996-03-15
    • Toshikazu Nakamura
    • Toshikazu Nakamura
    • A61K3818
    • C07K14/4753A61K38/1833
    • The invention relates to a therapeutic agent for disorder in brain and nerve containing HGF (hepatocyte growth factor) as an active ingredient, and a method for treatment of disorder in brain and nerve comprising administration of HGF. The active ingredient HGF possesses an action to prolong survival of brain and nerve cells, and the injured brain or nerves may be regenerated and restored. Therefore, the therapeutic agent and method for treatment of the invention are useful for prevention and treatment of various disorder in brain and nerve (for example, dementia, senile dementia of Alzheimer type, cerebral stroke, and cerebral infarction).
    • 本发明涉及含有HGF(肝细胞生长因子)作为活性成分的脑和神经疾病治疗剂,以及治疗脑和神经紊乱的方法,包括施用HGF。 活性成分HGF具有延长脑和神经细胞存活的作用,可以再生和恢复损伤的脑或神经。 因此,用于治疗本发明的治疗剂和方法可用于预防和治疗脑和神经中的各种障碍(例如,痴呆,老年痴呆型老年痴呆,脑卒中和脑梗死)。
    • 117. 发明授权
    • Semiconductor integrated circuit
    • 半导体集成电路
    • US06548903B2
    • 2003-04-15
    • US10066630
    • 2002-02-06
    • Toshikazu NakamuraToshiya Miyo
    • Toshikazu NakamuraToshiya Miyo
    • H01L2348
    • H01L23/5222H01L27/0207H01L27/10882H01L27/10885H01L2924/0002H01L2924/00
    • In the first and second regions data not concurrently transferred is transferred by using data lines having the respective different wiring layers. The vertical positions of the data lines are reversed between the first and second regions. In the switching regions the data lines are exchanged between the first and second regions. The parasitic capacitances associated with the two data lines are practically equal to each other so that the delay times of signals transferred along the data lines are equal to each other. This can prevent a circuit malfunction due to a parasitic capacitance difference. In the semiconductor integrated circuit where memory cell arrays and sense amplifier arrays are alternately wired, forming the first and second regions over the memory cell arrays and the switching regions over the sense amplifier arrays makes it easier to exchange the vertical positions of the data lines in the switching regions.
    • 在第一和第二区域中,通过使用具有各自的不同布线层的数据线来传送未并发传送的数据。 数据线的垂直位置在第一和第二区域之间相反。 在切换区域中,在第一和第二区域之间交换数据线。 与两个数据线相关联的寄生电容实际上彼此相等,使得沿着数据线传送的信号的延迟时间彼此相等。 这可以防止由寄生电容差引起的电路故障。 在其中存储单元阵列和读出放大器阵列交替布线的半导体集成电路中,在存储单元阵列和感测放大器阵列上的开关区域之间形成第一和第二区域使得更容易将数据线的垂直位置 开关区域。