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101. 发明授权

US5919231A Delivery system for voice prosthesis 失效
标题翻译：语音假体交付系统
公开(公告)号：US5919231A
公开(公告)日：1999-07-06
申请号：US408225
申请日：1995-03-22
申请人： Eric D. Blom , W. Gregory Chernoff , Daniel W. Karakla
发明人： Eric D. Blom , W. Gregory Chernoff , Daniel W. Karakla
IPC分类号： A61B17/00 , A61F2/18 , A61F2/20
CPC分类号： A61F2/203 , A61F2/186 , A61B17/0057 , A61B2017/00659
摘要： A device for insertion into a first opening in a body includes a device body having a longitudinal axis and a flexible first flange provided on an outside surface of the device body. The first flange has a deployed, use orientation in which it projects generally outwardly from the outside surface of the device body and an undeployed, insertion orientation in which it is resiliently deflected toward the device body. A retainer retains the flange in its insertion orientation. The retainer is constructed of a material soluble in a fluid.
摘要翻译：用于插入主体中的第一开口的装置包括具有纵向轴线的装置主体和设置在装置主体的外表面上的柔性第一凸缘。第一凸缘具有展开的使用方向，其中，其从装置主体的外表面大致向外突出并且具有未被部署的插入取向，其中弹性偏转朝向装置主体。保持器将凸缘保持在其插入方向。保持器由可溶于流体的材料构成。

102. 发明授权

US5658516A Method of making a prospthetic implant 失效
标题翻译：制造假体植入物的方法
公开(公告)号：US5658516A
公开(公告)日：1997-08-19
申请号：US444033
申请日：1995-05-18
申请人： Barry Eppley , Thomas Sander , Robert D. Torgerson
发明人： Barry Eppley , Thomas Sander , Robert D. Torgerson
IPC分类号： A61F2/00 , A61F2/02 , A61F2/18 , A61F2/28 , A61F2/30 , A61L27/26 , B29C45/14 , B29C33/12
CPC分类号： A61F2/30721 , A61F2/2803 , A61F2/2875 , A61L27/26 , A61F2/18 , A61F2/186 , A61F2002/2807 , A61F2002/281 , A61F2002/2882 , A61F2002/2885 , A61F2002/2889 , A61F2002/30062 , A61F2002/30166 , A61F2002/30329 , A61F2002/30571 , A61F2002/30708 , A61F2002/30736 , A61F2002/30957 , A61F2002/30962 , A61F2210/0004 , A61F2220/0025 , A61F2230/0028 , A61F2250/0084 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179
摘要： Flexible prosthetic implants for repairing, replacing or augmenting hard tissue or bone. The flexible implant comprises a plurality of segments that are connected by flexible retainers which enable the segments to be re-oriented in relation to one another to accommodate the contour, size and shape of the body part being treated. A method for making such flexible prosthetic implants is also disclosed.
摘要翻译：用于修复，更换或增加硬组织或骨骼的柔性假体植入物。柔性植入物包括通过柔性保持器连接的多个段，其使得段能够相对于彼此重新定向以适应待处理的身体部位的轮廓，尺寸和形状。还公开了制造这种柔性假体植入物的方法。

103. 发明授权

US5496371A Prosthetic implant 失效
标题翻译：假体植入物
公开(公告)号：US5496371A
公开(公告)日：1996-03-05
申请号：US69452
申请日：1993-06-01
申请人： Barry Eppley , Thomas Sander , Robert D. Torgerson
发明人： Barry Eppley , Thomas Sander , Robert D. Torgerson
IPC分类号： A61F2/00 , A61F2/02 , A61F2/18 , A61F2/28 , A61F2/30 , A61L27/26
CPC分类号： A61F2/30721 , A61F2/2803 , A61F2/2875 , A61L27/26 , A61F2/18 , A61F2/186 , A61F2002/2807 , A61F2002/281 , A61F2002/2882 , A61F2002/2885 , A61F2002/2889 , A61F2002/30062 , A61F2002/30166 , A61F2002/30329 , A61F2002/30571 , A61F2002/30708 , A61F2002/30736 , A61F2002/30957 , A61F2002/30962 , A61F2210/0004 , A61F2220/0025 , A61F2230/0028 , A61F2250/0084 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179
摘要： Flexible prosthetic implants for repairing, replacing or augmenting hard tissue or bone. The flexible implant comprises a plurality of segments that are connected by flexible retainers which enable the segments to be re-oriented in relation to one another to accommodate the contour, size and shape of the body part being treated. A method for making such flexible prosthetic implants is also disclosed.
摘要翻译：用于修复，更换或增加硬组织或骨骼的柔性假体植入物。柔性植入物包括通过柔性保持器连接的多个段，其使得段能够相对于彼此重新定向以适应待处理的身体部位的轮廓，尺寸和形状。还公开了制造这种柔性假体植入物的方法。

104. 发明授权

US5423858A Septoplasty fasteners and device for applying same 失效
标题翻译：缝合成型紧固件和应用它的装置
公开(公告)号：US5423858A
公开(公告)日：1995-06-13
申请号：US129910
申请日：1993-09-30
申请人： Henry Bolanos , Dominick L. Mastri , Wayne P. Young , Boris Zvenyatsky
发明人： Henry Bolanos , Dominick L. Mastri , Wayne P. Young , Boris Zvenyatsky
IPC分类号： A61B17/00 , A61B17/064 , A61B17/068 , A61B17/24 , A61B17/28 , A61F2/18 , A61L31/06 , A61B17/04
CPC分类号： A61B17/068 , A61B17/0057 , A61B17/0643 , A61L31/06 , A61B17/24 , A61B17/282 , A61B2017/00004 , A61B2017/00659 , A61B2017/0647 , A61F2/186 , Y10S411/922 , Y10T24/309 , Y10T24/42
摘要： A two-part fastener for use in septoplasty procedures includes a fastener portion having a base with shaft extending perpendicularly therefrom and a retainer having an aperture for engagement with the shaft. The fastener may include indexing means for positioning the retainer in engagement with the fastener portion at discrete spaced apart locations along the shaft. In another embodiment the shaft is slightly larger in diameter than the aperture in the retainer to effect a frictional engagement. Applicator instruments are also provided. In one embodiment the applicator includes two elongated members pivotally connected in the middle. In another embodiment the applicator includes an elongated body which holds a plurality of septoplasty fasteners. A pivotally connected lower jaw holds a supply of retainers. A pusher member drives the fastener through a curved firing chamber, through body tissue, and into engagement with the retainer.
摘要翻译：用于间隔成形术程序的两部分紧固件包括紧固件部分，其具有带有从其垂直延伸的轴的基部和具有用于与轴接合的孔的保持器。紧固件可以包括分度装置，用于将保持器定位成沿着轴在离散的间隔开的位置处与紧固件部分接合。在另一个实施例中，轴的直径略大于保持器中的孔以实现摩擦接合。还提供施放器乐器。在一个实施例中，施加器包括在中间枢转地连接的两个细长构件。在另一个实施例中，施放器包括一个细长体，其保持多个隔膜成形术紧固件。枢轴连接的下颌保持一定量的保持器。推动器构件通过弯曲的燃烧室驱动紧固件穿过身体组织并与保持器接合。

105. 发明授权

US5246455A Middle meatal antrostomy ventilation tube 失效
标题翻译：中间肉制造型通气管
公开(公告)号：US5246455A
公开(公告)日：1993-09-21
申请号：US702585
申请日：1991-05-17
申请人： Alain H. Shikani
发明人： Alain H. Shikani
IPC分类号： A61F2/18 , A61F2/82 , A61F11/00
CPC分类号： A61F2/18 , A61F11/002 , A61F2/186 , A61F2/82
摘要： An implantable ventilation tube for insertion in bodily tissues is disclosed. A suggested use for such a tube is as a middle meatal antrostomy ventilation tube for use following endoscopic surgery. It consists of a pair of flanges and a central tubular vent section extending therebetween, having the flanges positioned perpendicular to the lumen of the central tubular vent section. The tube is preferably made of elastomeric material and may include grooves etched in the distal surface of the distal flange to assist in insertion by permitting materials of a higher durometer rating than silastic.RTM. to be folded then grasped during insertion. It is suggested that the proximal flange be generally rectangular shaped, while the distal flange be generally triangular shaped, to ease insertion yet enhance anchoring capabilities. Once properly positioned through an opening prepared in a body cavity or duct, the ventilation tube permits the unhindered flow of fluids, such as air, through the lumen.
摘要翻译：公开了用于插入身体组织中的可植入通气管。这种管的建议用途是作为内窥镜手术后使用的中间肉制造型通气管。它由一对凸缘和一个在其间延伸的中央管状通气部分组成，其中凸缘与中心管状通气部分的内腔垂直。管优选地由弹性体材料制成，并且可以包括蚀刻在远侧凸缘的远侧表面中的槽，以帮助插入，允许比硅橡胶TM更高的硬度计的材料在插入期间被折叠。建议近侧凸缘大致为矩形，而远侧凸缘为大致三角形，以方便插入，增强锚固能力。一旦通过准备在体腔或管道中的开口适当地定位，通气管允许诸如空气的流体不受阻碍地流过内腔。

106. 发明授权

US4994084A Reconstructive surgery method and implant 失效
标题翻译：重建手术方法和植入
公开(公告)号：US4994084A
公开(公告)日：1991-02-19
申请号：US370453
申请日：1989-06-23
申请人： H. George Brennan
发明人： H. George Brennan
IPC分类号： A61F2/00
CPC分类号： A61F2/0059 , A61F2/186
摘要： A homograft implant is made from prepackaged, processed homograft material. The homograft material is taken in its purchased dehydrated form and cut into strips of varying shapes and sized. The strips are then adhesively secured together in a laminar manner by a tissue adhesive to form the desired shape and density of the implant. Once the implant has been made, it may then be surgically implanted in a desired location, immediately beneath the patient's dermis so as to alter the exterior appearance of the patient at the implant site. Since the implant is formed of dehydrated homograft material, endogenous tissue readily attaches to the implant after a short period of time, so that the implant becomes integral with the body.
摘要翻译：同种移植物由预包装的加工同种植物材料制成。将同种植物材料以其购买的脱水形式取出并切成不同形状和尺寸的条。然后通过组织粘合剂以片状的方式将条带粘合地固定在一起，以形成植入物的期望形状和密度。一旦植入物已经制成，然后可以将其随机地植入位于病人真皮下面的所需位置，以改变患者在植入部位的外观。由于植入物由脱水同种植物材料形成，内源性组织在短时间内容易地附着到植入物上，使得植入物与身体成为一体。

107. 发明授权

US3766924A Nasal tampons 失效
标题翻译： NASAL TAMPONS
公开(公告)号：US3766924A
公开(公告)日：1973-10-23
申请号：US3766924D
申请日：1972-01-26
申请人： MATBURN LTD
发明人： PIDGEON R
IPC分类号： A61B17/12
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12104 , A61B17/24 , A61F2/186
摘要： A nasal tampon, that is to say a device for arresting nasal haemorrhage comprises a lumen tube an end of which can be entered into the nostril of a patient. An inflatable balloon is provided at this end of the lumen tube and a closure is provided at the other end. The balloon can be inflated by passing air through the lumen tube. An inflatable sleeve or cuff is slidable on the outside of the lumen tube. An inflation tube leads to the inflatable sleeve or cuff and a closure is provided at the end of the inflation tube.
摘要翻译：鼻塞，也就是说用于阻止鼻出血的装置包括管腔，其末端可以进入患者的鼻孔。在管腔的该端部设置有可充气气囊，另一端设有闭合件。气囊可以通过使空气通过管腔而膨胀。可充气套筒或袖口可在管腔外侧滑动。充气管通向可膨胀的套筒或袖口，并且在充气管的端部设置封闭件。

108. 发明公开

US20240358893A1 IMPLANTABLE SCAFFOLDS FOR TREATMENT OF SINUSITIS 审中-公开
公开(公告)号：US20240358893A1
公开(公告)日：2024-10-31
申请号：US18769827
申请日：2024-07-11
申请人： LYRA THERAPEUTICS, INC.
发明人： Changcheng You , Quynh Pham , Danny Concagh
IPC分类号： A61L27/34 , A61F2/18 , A61F2/90 , A61K31/58 , A61L27/18 , A61L27/54 , A61L27/56 , A61L27/58 , A61M25/10 , A61M31/00
CPC分类号： A61L27/34 , A61F2/186 , A61F2/90 , A61K31/58 , A61L27/18 , A61L27/54 , A61L27/56 , A61L27/58 , A61M25/10 , A61M31/002 , A61F2210/0004 , A61F2250/0031 , A61F2250/0067 , A61L2300/222 , A61L2300/41 , A61L2300/604 , A61L2300/608 , A61M2025/105 , A61M2210/0681
摘要： This disclosure describes, inter alia, materials, devices, kits and methods that may be used to treat chronic sinusitis. More specifically, a drug-eluting scaffold is implanted in the middle meatus to treat chronic sinusitis for weeks to months.

109. 发明授权

US12064339B2 Implantable scaffolds for treatment methods of sinusitus 有权
公开(公告)号：US12064339B2
公开(公告)日：2024-08-20
申请号：US17034383
申请日：2020-09-28
申请人： Lyra Therapeutics, Inc.
发明人： Changcheng You , Quynh Pham , Danny Concagh
IPC分类号： A61F2/18 , A61F2/90 , A61K31/58 , A61L27/18 , A61L27/26 , A61L27/34 , A61L27/54 , A61L27/56 , A61L31/06 , A61L31/10
CPC分类号： A61F2/18 , A61F2/90 , A61K31/58 , A61L27/18 , A61L27/26 , A61L27/34 , A61L27/54 , A61L27/56 , A61L31/06 , A61L31/10 , A61F2/186 , A61F2210/0004 , A61F2250/0031 , A61F2250/0067 , A61L2300/222 , A61L2300/41 , A61L2300/604 , A61L2300/608 , A61L27/18 , C08L67/02 , A61L27/34 , C08L67/02 , A61L31/06 , C08L67/04 , A61L31/10 , C08L67/04
摘要： This disclosure describes various sinus scaffolds having fiber-based and non-fiber based designs, materials, devices, kits and methods that may be used to treat chronic sinusitis. These designs vary in form, dimension, and delivery location (i.e., maxillary, frontal, ethmoidal, sphenoidal sinuses, and middle meatus). In addition, therapeutic agent(s) may optionally be included within the scaffolds for local delivery over a brief or extended period of time.

110. 发明公开

US20240252246A1 IMPLANT MANUFACTURING METHOD FOR DESIGNING IMPLANT ON BASIS OF MEDICAL IMAGE DATA AND VIRTUAL IMAGE DATA 审中-公开
公开(公告)号：US20240252246A1
公开(公告)日：2024-08-01
申请号：US18038624
申请日：2021-11-24
申请人： ANYMEDI INC.
发明人： Gukbae KIM , Seunghyun CHOI , Hye Sung LEE , Bong Saeng KIM
IPC分类号： A61B34/10 , A61F2/18 , B33Y50/00 , G06F30/12 , G16H50/50
CPC分类号： A61B34/10 , A61F2/186 , G06F30/12 , G16H50/50 , A61B2034/104 , A61B2034/105 , A61B2034/108 , A61F2240/002 , B33Y50/00
摘要： The present invention relates to a method for fabricating an implant, comprising: (a) acquiring patient medical imaging data to define the appearance prior to the implant's insertion and a seating surface where the implant is seated, (b) acquiring a virtual image data defining the appearance after the implant's insertion, and (c) designing the implant based on the acquired patient medical imaging data and the virtual imaging data, wherein, the step of (c) includes determining a shape and height of the implant based on a difference between an appearance prior to the implant's insertion and an appearance after the implant's insertion, based on a seating surface defined from the acquired patient medical imaging data. This allows for a more comfortable fit of the implant to the nasal bone and cartilage, while achieving a post-operative appearance that is consistent with the intentions of the surgeon and patient.

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