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    • 95. 发明申请
    • Biosensor structure and fabricating method thereof
    • 生物传感器结构及其制造方法
    • US20090191616A1
    • 2009-07-30
    • US12231071
    • 2008-08-27
    • Yi-Chun LuTri-Rung YewHwan-You ChangYa-Shuan Chuang
    • Yi-Chun LuTri-Rung YewHwan-You ChangYa-Shuan Chuang
    • C12M1/00
    • G01N33/48728
    • A biosensor structure and a method for fabricating the same are described. The biosensor structure for detecting at least a single cell includes a substrate with an insulating surface, a conductive layer and a plurality of capture molecules. The conductive layer is disposed on the substrate, and has a first pattern and a second pattern separated from each other. The first pattern includes a plurality of first finger configurations, and the second pattern includes a plurality of second finger configurations, so as to form interdigitated array. The capture molecules are immobilized on the conductive layer, such that the cell that is bound specifically to the capture molecules on two adjacent first and second finger configurations is detected. The biosensor structure is feasible for real-time (
    • 对生物传感器结构及其制造方法进行说明。 用于检测至少单个电池的生物传感器结构包括具有绝缘表面的基板,导电层和多个捕获分子。 导电层设置在基板上,并且具有彼此分离的第一图案和第二图案。 第一图案包括多个第一手指配置,并且第二图案包括多个第二手指配置,以便形成相互指向的数组。 捕获分子被固定在导电层上,使得在两个相邻的第一和第二手指配置上特异性结合捕获分子的细胞被检测。 生物传感器结构对于单个细胞的实时(<3分钟),特异性和定量靶向细胞检测是可行的。
    • 98. 发明授权
    • Gradient barrier layer for copper back-end-of-line technology
    • 用于铜后端技术的梯度屏障层
    • US07067917B2
    • 2006-06-27
    • US10337292
    • 2003-01-07
    • Fu-Tai LiouCheng-Yu HungTri-Rung Yew
    • Fu-Tai LiouCheng-Yu HungTri-Rung Yew
    • H01L23/48H01L23/52H01L29/40
    • H01L21/76846C23C14/027C23C14/0641C23C16/029C23C16/34H01L21/2855H01L21/28556H01L21/76805H01L21/76864H01L23/53238H01L2924/0002Y10T428/26H01L2924/00
    • The present invention is directed to a structure of a gradient barrier layer. The gradient barrier with a composite structure of metal/metal salt of different composition/metal such as Ta/TaxN1−x/TaN/TaxN1−x/Ta (tantalum/tantalumx nitride1−x/tantalum nitride/tantalumx nitride1−x/tantalum) is proposed to replace the conventional barrier for copper metallization. The gradient barrier can be formed in a chemical vapor deposition (CVD) process or a multi-target physical vapor deposition (PVD) process. For CVD process, using the characteristics of well-controlled reaction gas injection, the ratio of tantalum (Ta) and nitrogen (N) can be modulated gradually to form the gradient barrier. For the multi-target PVD process, the gradient barrier is formed by depositing multi-layers of different composition TaxN1−x films. After subsequent thermal cycle processes such as metal alloy, the inter-layer diffusion occurs and a more smooth distribution of Ta and N is achieved for the gradient barrier. The advantages of forming the gradient barrier include a well-controlled process, a strong adhesion between via and landing metal, more uniform step coverage, and less brittle to reduce crack.
    • 本发明涉及梯度阻挡层的结构。 具有不同成分/金属的金属/金属盐的复合结构的梯度屏障,例如Ta / Ta x N 1-x / TaN / Ta x x 1 / x 1 / x 3/1 / x 2/1 / x 3 / 提出了替代传统的铜金属化屏障的方法。 梯度屏障可以在化学气相沉积(CVD)工艺或多目标物理气相沉积(PVD)工艺中形成。 对于CVD工艺,使用良好控制的反应气体注入特性,可以逐渐调节钽(Ta)和氮(N)的比例,形成梯度屏障。 对于多目标PVD工艺,通过沉积多层不同组成的Ta x N 1 x-x膜形成梯度屏障。 在随后的热循环过程如金属合金之后,发生层间扩散,并且对梯度屏障实现了更平稳的Ta和N分布。 形成梯度屏障的优点包括良好控制的工艺,通孔和着陆金属之间的牢固粘附,更均匀的台阶覆盖,并且较不易碎以减少裂纹。