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91. 发明授权

US07329369B2 Semiconductor nanoparticle surface modification method 有权
标题翻译：半导体纳米颗粒表面改性方法
公开(公告)号：US07329369B2
公开(公告)日：2008-02-12
申请号：US11325533
申请日：2006-01-05
申请人： Keiichi Sato , Shinya Hattori , Taeko Chiba
发明人： Keiichi Sato , Shinya Hattori , Taeko Chiba
IPC分类号： C09K11/02 , C09K11/08
CPC分类号： C09K11/02 , B82Y30/00 , C09K11/08 , G01N33/54346 , G01N33/54353 , G01N33/582 , Y10S977/773 , Y10S977/902
摘要： Semiconductor nanoparticles having high luminescence properties that are preferable for applications and uses of biotechnology are provided.With the use of electric charges on the surfaces of particles, the particles and selected polymers are allowed to electrostatically bind to each other, such that the surfaces of the particles are coated. The polymers are allowed to crosslink to each other, resulting in the improved durability of the particles. Further, functional groups contained in the polymers are exposed on the surfaces of the particles. Accordingly, semiconductor nanoparticles that are preferably utilized for applications such as staining and labeling of biopolymers have been synthesized.
摘要翻译：提供了对于生物技术的应用和使用优选的具有高发光特性的半导体纳米颗粒。通过在颗粒表面上使用电荷，允许颗粒和选定的聚合物彼此静电结合，使得颗粒的表面被涂覆。允许聚合物彼此交联，从而提高颗粒的耐久性。此外，包含在聚合物中的官能团暴露在颗粒的表面上。因此，已经合成了优选用于生物聚合物的染色和标记等应用的半导体纳米颗粒。

92. 发明申请

US20070237448A1 Method for inspecting peeling in adhesive joint 有权
标题翻译：粘接剂剥离检查方法
公开(公告)号：US20070237448A1
公开(公告)日：2007-10-11
申请号：US11783073
申请日：2007-04-05
申请人： Keiichi Sato , Hideaki Murayama , Kazuro Kageyama
发明人： Keiichi Sato , Hideaki Murayama , Kazuro Kageyama
IPC分类号： G02B6/00
CPC分类号： G02B6/022 , G01M11/086 , G01N19/04 , G02B6/02204
摘要： A method is disclosed wherein a portion of a sensor part of an optical fiber sensor is embedded in an adhesive between two joined members, and peeling in an adhesive joint of the two members is detected on the basis of measuring optical characteristics from the optical fiber sensor when the optical fiber sensor is irradiated with light from a light source while one member is vibrated by vibration means. The method comprises the steps of determining the temperature of the two members during measurement on the basis of the optical characteristics from the sensor part exposed outside of the adhesive; determining, on the basis of the temperature determined during the measurement, the measurement range in which the optical characteristics from the optical fiber sensor are measured; and measuring the variation in the optical characteristics from the optical fiber sensor within the determined measurement range while the member is being vibrated by the vibration means.
摘要翻译：公开了一种方法，其中光纤传感器的传感器部分的一部分嵌入两个接合部件之间的粘合剂中，并且基于来自光纤传感器的测量光学特性来检测两个部件的粘合接合部中的剥离当光纤传感器被来自光源的光照射时，一个部件被振动装置振动。该方法包括以下步骤：基于暴露于粘合剂外部的传感器部件的光学特性来确定测量期间两个部件的温度; 基于测量期间确定的温度，确定测量来自光纤传感器的光学特性的测量范围; 并且在所述构件被振动装置振动的同时，在确定的测量范围内测量光纤传感器的光学特性的变化。

93. 外观设计

USD548231S1 Optical pickup 有权
公开(公告)号：USD548231S1
公开(公告)日：2007-08-07
申请号：US29260491
申请日：2006-05-26
申请人： Keiichi Sato
设计人： Keiichi Sato

94. 发明申请

US20070077587A1 Method of detecting a biopolymer and device for the same 审中-公开
标题翻译：检测生物聚合物的方法及其装置
公开(公告)号：US20070077587A1
公开(公告)日：2007-04-05
申请号：US11542245
申请日：2006-10-04
申请人： Keiichi Sato
发明人： Keiichi Sato
IPC分类号： C12Q1/68
CPC分类号： G01N33/54393
摘要： Provided is a method of achieving a simple, quick, and highly accurate detection and measurement of a biopolymer, and to provide a device for this purpose. To this end, a method of detecting a biopolymer utilizing two kinds of solvent phases different in property from each other, including steps of: allowing a sample biopolymer to react with a labeled probe biopolymer in the first solvent phase; transferring a product of the reaction of the sample biopolymer with the probe biopolymer to a second solvent phase using a medium having surface activity between the two kinds of solvent phases; and detecting the reaction product contained in the second solvent phase by use of the label.
摘要翻译：提供了一种实现生物聚合物的简单，快速和高精度检测和测量的方法，并为此提供了一种装置。为此，使用两种不同性质的溶剂相检测生物聚合物的方法，包括以下步骤：允许样品生物聚合物与第一溶剂相中的标记探针生物聚合物反应; 使用在两种溶剂相之间具有表面活性的介质将样品生物聚合物与探针生物聚合物的反应产物转移到第二溶剂相; 并通过使用该标签检测第二溶剂相中所含的反应产物。

95. 发明申请

US20070065665A1 NANOPARTICLES AND PRODUCTION THEREOF 有权
标题翻译：纳米粒及其生产
公开(公告)号：US20070065665A1
公开(公告)日：2007-03-22
申请号：US10853279
申请日：2004-05-26
申请人： Keiichi Sato , Susumu Kuwabata , Tsukasa Torimoto
发明人： Keiichi Sato , Susumu Kuwabata , Tsukasa Torimoto
IPC分类号： B32B1/00 , B32B19/00 , B32B23/02 , B32B27/02 , B32B9/00 , B32B17/02 , B32B21/02 , B32B15/02 , B32B5/16
CPC分类号： B82Y30/00 , C01G1/00 , C01G1/02 , C01G1/12 , C01G11/02 , C01P2002/84 , C01P2004/64 , C09K11/02 , C09K11/565 , Y10S977/895 , Y10T428/2982
摘要： Monodisperse nanoparticles are prepared with a high degree of reproducibility by controlling pH in size-selective photoetching. The nanoparticles have uniform optical properties and other properties.
摘要翻译：通过控制尺寸选择性光刻中的pH，以高度重现性制备单分散纳米颗粒。纳米颗粒具有均匀的光学性质和其他性质。

96. 发明申请

US20060281129A1 Method for detecting biopolymers 审中-公开
公开(公告)号：US20060281129A1
公开(公告)日：2006-12-14
申请号：US11506839
申请日：2006-08-21
申请人： Kanako Iwao , Motonao Nakao , Keiichi Sato , Toshiki Morita , Susumu Kuwabata
发明人： Kanako Iwao , Motonao Nakao , Keiichi Sato , Toshiki Morita , Susumu Kuwabata
IPC分类号： C12Q1/68 , G01N33/53 , C12M1/34
CPC分类号： G01N33/54353
摘要： A technique is provided that easily detects biopolymers such as a DNA or a protein by utilizing semiconductor nanoparticles having different excitation wavelengths and fluorescence due to differences in particle size. By binding the semiconductor nanoparticles with avidin (or biotin), detection of biopolymers labeled with biotin (or avidin) is enabled.

97. 发明申请

US20060058443A1 Process for producing carbon nanotube reinforced composite material 失效
标题翻译：生产碳纳米管增强复合材料的工艺
公开(公告)号：US20060058443A1
公开(公告)日：2006-03-16
申请号：US11088328
申请日：2005-03-23
申请人： Toshiyuki Ohashi , Keiichi Sato , Kazuhiro Miura
发明人： Toshiyuki Ohashi , Keiichi Sato , Kazuhiro Miura
IPC分类号： C08K3/04
CPC分类号： C08J5/04 , B82Y30/00 , C08J3/2053 , C08J5/005 , C08K7/24 , D01F11/122
摘要： An object is to provide a process for producing a carbon nanotube (CNT) reinforced composite material, wherein CNT is homogeneously dispersed in a resin to obtain the composite material having an excellent mechanical strength. Hydrophilic CNTs 12 are dispersed in a first solvent 11 to prepare a first dispersion liquid 13. The dispersion liquid 13 and a synthetic resin raw material 15 are added to a second solvent 14 and the resulting mixture is stirred to prepare a third dispersion liquid 17 where a second dispersion liquid 16 in which the synthetic resin raw material 15 is dissolved in the dispersion liquid 13 is dispersed in the solvent 14. The solvents 11 and 14 are removed from the dispersion liquid 17 to obtain a mixture of the hydrophilic CNTs 12 and the synthetic resin raw material 15. The mixture is molded to obtain the composite material in which the synthetic resin is reinforced with the hydrophilic CNTs 12. The second solvent 14 has smaller solubility of the synthetic resin raw material 15 than that of the solvent 11, is substantially not compatible to the solvent 11, and has volume larger than that of the solvent 11. The dispersion liquid 17 is sprayed on a substrate and the solvents 11 and 14 are removed to obtain the mixture and simultaneously to conduct molding of the mixture.
摘要翻译：本发明的目的是提供一种碳纳米管（CNT）增强复合材料的制造方法，其中，CNT均匀地分散在树脂中，得到机械强度优异的复合材料。将亲水性CNT 12分散在第一溶剂11中以制备第一分散液13。将分散液13和合成树脂原料15加入到第二溶剂14中，搅拌所得混合物以制备第三分散液17，其中合成树脂原料15溶解在分散体中的第二分散液16 液体13分散在溶剂14中。从分散液17中除去溶剂11和14，得到亲水性碳纳米管12和合成树脂原料15的混合物。将该混合物成形，得到合成树脂用亲水性CNT 12增强的复合材料第二溶剂14的合成树脂原料15的溶解度小于溶剂11的溶解性，与溶剂11基本上不相容，体积大于溶剂11的体积。将分散液17喷雾到底物和溶剂11和14被除去以获得混合物并同时进行混合物的模制。

98. 发明授权

US06977182B2 Semiconductor nanoparticles, method for producing the same, and fluorescence reagent comprising semiconductor nanoparticles 失效
标题翻译：半导体纳米粒子，其制造方法以及含有半导体纳米粒子的荧光试剂
公开(公告)号：US06977182B2
公开(公告)日：2005-12-20
申请号：US10622651
申请日：2003-07-21
申请人： Keiichi Sato , Susumu Kuwabata
发明人： Keiichi Sato , Susumu Kuwabata
IPC分类号： G01N21/64 , C01G11/02 , C09C1/00 , C09C1/04 , C09C1/10 , C09C1/14 , C09C1/36 , C09C1/38 , C09C3/12 , C09K11/08 , C09K11/54 , C09K11/56 , C09K11/66 , C09K11/67 , C09K11/68 , C09K11/70 , C09K11/74 , C09K11/88 , H01L21/00
CPC分类号： B82Y30/00 , C01P2004/64 , C09C1/00 , C09C1/04 , C09C1/10 , C09C1/14 , C09C1/3607 , C09C1/38 , C09C3/12 , C09K11/565
摘要： This invention provides semiconductor nanoparticles having fluorescence properties and comprising a modifying group represented by the following general formula bound to their surfaces, a method for producing the same, and a fluorescence reagent comprising semiconductor nanoparticles: —OY wherein Y is selected from a hydrogen atom, a metal atom, a semimetal atom, an organic group, or an organic group that is intermediated by a metal atom or a semimetal atom. In this method, the surfaces of the semiconductor nanoparticles were modified with a hydroxyl group or the like for stabilization. This realizes the production of semiconductor nanoparticles having fluorescence properties that significantly emit only the band gap fluorescence, the production of which at the industrial level was previously very difficult due to the necessity of many processes and from the viewpoint of technology and safety.
摘要翻译：本发明提供了具有荧光特性的半导体纳米粒子，其包含由与其表面结合的下述通式表示的改性基团，其制造方法以及包含半导体纳米粒子的荧光试剂：<？in-line-formula description =“In - 线公式“end =”lead“？> - OY <？in-line-formula description =”In-line Formulas“end =”tail“？>其中Y选自氢原子，金属原子，半金属原子，有机基团或被金属原子或半金属原子中间化的有机基团。在该方法中，用羟基等改性半导体纳米颗粒的表面以进行稳定化。这实现了具有荧光特性的半导体纳米颗粒的生产，其显着地仅发射带隙荧光，由于需要许多工艺以及从技术和安全性的观点来看，其工业级的生产以前是非常困难的。

99. 发明申请

US20050136470A1 Apparatus for detecting biopolymers and cartridge 失效
标题翻译：用于检测生物聚合物和药筒的装置
公开(公告)号：US20050136470A1
公开(公告)日：2005-06-23
申请号：US11048918
申请日：2005-02-03
申请人： Keiichi Sato , Mitsuhiro Tachibana , Toshiki Morita , Motonao Nakao
发明人： Keiichi Sato , Mitsuhiro Tachibana , Toshiki Morita , Motonao Nakao
IPC分类号： G01N33/53 , C12M1/00 , C12M1/34 , C12N15/09 , C12Q1/68 , G01N21/01 , G01N21/03 , G01N27/447 , G01N33/566
CPC分类号： G01N27/44704 , C12Q1/6825 , G01N27/44721 , G01N27/4473 , C12Q2565/607 , C12Q2565/518
摘要： Provided is an apparatus for detecting biopolymers (DNA) capable of total analysis including non-reacted samples without complicated operations such as washing. A DNA probe is fixed to one of electrodes and direct current voltage is placed between the electrodes, so that it becomes possible to separate complementary strand sample DNA and non-complementary strand sample DNA. By analyzing from a ratio in the whole reaction system, it is possible to obtain clearer results. Further, by using electrophoresis by gel together, it is possible to separate reacted samples and non-reacted samples to perform measurements therefor in the same reaction field.
摘要翻译：提供了一种用于检测能够进行总体分析的生物聚合物（DNA）的装置，包括没有复杂操作如洗涤的未反应样品。将DNA探针固定在电极之一中，并且将直流电压置于电极之间，使得可以分离互补链样品DNA和非互补链样品DNA。通过从整个反应系统的比例分析，可以获得更清楚的结果。此外，通过使用凝胶电泳在一起，可以在相同的反应场中分离反应的样品和未反应的样品以进行测量。

100. 发明授权

US06875603B2 Apparatus for detecting biopolymers and cartridge 失效
标题翻译：用于检测生物聚合物和药筒的装置
公开(公告)号：US06875603B2
公开(公告)日：2005-04-05
申请号：US10001012
申请日：2001-11-30
申请人： Keiichi Sato , Mitsuhiro Tachibana , Toshiki Morita , Motonao Nakao
发明人： Keiichi Sato , Mitsuhiro Tachibana , Toshiki Morita , Motonao Nakao
IPC分类号： G01N33/53 , C12M1/00 , C12M1/34 , C12N15/09 , C12Q1/68 , G01N21/01 , G01N21/03 , G01N27/447 , G01N33/566 , C12M3/00
CPC分类号： G01N27/44704 , C12Q1/6825 , G01N27/44721 , G01N27/4473 , C12Q2565/607 , C12Q2565/518
摘要： Provided is an apparatus for detecting biopolymers (DNA) capable of total analysis including non-reacted samples without complicated operations such as washing.A DNA probe is fixed to one of electrodes and direct current voltage is placed between the electrodes, so that it becomes possible to separate complementary strand sample DNA and non-complementary strand sample DNA. By analyzing from a ratio in the whole reaction system, it is possible to obtain clearer results. Further, by using electrophoresis by gel together, it is possible to separate reacted samples and non-reacted samples to perform measurements therefor in the same reaction field.
摘要翻译：本发明提供一种用于检测能够进行总体分析的生物聚合物（DNA）的装置，包括未进行复杂操作的洗涤等未反应的样品。将DNA探针固定在电极中的一个上，并将直流电压置于电极之间，分离互补链样品DNA和非互补链样品DNA。通过从整个反应系统的比例分析，可以获得更清楚的结果。此外，通过使用凝胶电泳在一起，可以在相同的反应场中分离反应的样品和未反应的样品以进行测量。

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