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    • 5. 发明授权
    • 티오메틸페놀 유도체의 제조방법
    • 一种制备三甲苯酚的方法
    • KR100813173B1
    • 2008-03-17
    • KR1020060096110
    • 2006-09-29
    • 금호석유화학 주식회사
    • 이형재김진억
    • C07C323/18C07C321/24
    • A method for preparing a thiomethylphenol derivative is provided to prevent oxidation and discoloration of a thiomethylphenol derivative produced in the presence of a base, and to allow application of a colorless thiomethylphenol derivative in various industrial fields. A method for preparing a thiomethylphenol derivative comprises the steps of: reacting a phenol derivative represented by the following formula 2, a mercaptan derivative represented by the formula of R2SH and paraformaldehyde in the presence of a C4-C10 heterocyclic amine type base and an acid to obtain a thiomethylphenol derivative represented by the following formula 1; and washing and purifying the resultant product with 1-50 equivalents of an acid per equivalent of the base. In formulae 1 and 2, R1 is H, a C1-C16 linear or branched alkyl, or aromatic group-containing alkyl; R2 is a C1-C16 linear or branched alkyl or aromatic group-containing alkyl; X is H, -(CH2)n-, -CMe2- or -Y-, wherein Y is an aromatic compound such as benzene, biphenyl, toluene or naphthalene, or an aromatic compound substituted with at least one alkyl group; n is 0 or an integer of 1-8; and m is 0 or 1.
    • 提供了制备硫代甲基苯酚衍生物的方法,以防止在碱存在下产生的硫代甲基苯酚衍生物的氧化和变色,并允许在各种工业领域中使用无色硫代甲基苯酚衍生物。 一种制备硫代甲基苯酚衍生物的方法包括以下步骤:使由下式2表示的苯酚衍生物,由式R2SH表示的硫醇衍生物和多聚甲醛在C4-C10杂环胺型碱存在下与酸反应 得到下式1表示的硫代甲基苯酚衍生物; 并用每当量碱的1-50当量酸洗涤和纯化所得产物。 在式1和2中,R 1是H,C 1 -C 16直链或支链烷基或含芳基的烷基; R2是C1-C16直链或支链烷基或含芳基的烷基; X为H, - (CH 2)n - , - Me 2 - 或-Y-,其中Y为苯,联苯,甲苯或萘等芳香族化合物或被至少一个烷基取代的芳香族化合物。 n为0或1-8的整数; m为0或1。