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    • 5. 发明公开
    • 비만 예방 또는 치료제의 스크리닝 방법
    • 筛选用于治疗或预防肥胖症的药剂的方法
    • KR1020130009207A
    • 2013-01-23
    • KR1020110070125
    • 2011-07-14
    • 경상대학교산학협력단
    • 김명옥신성철김소은이혜령전은우정종일박문석
    • G01N33/68G01N33/15
    • G01N33/6872A61K31/7048C12Q1/6883C12Q2600/136G01N33/74G01N33/9426G01N2333/5755G01N2333/726G01N2800/042G01N2800/044
    • PURPOSE: A capsule formulation containing an independent levocetirizine layer for preventing or treating allergic rhinitis and asthma is provided to ensure excellent product stability and to maximize treatment effect. CONSTITUTION: A capsule formulation for preventing or treating allergic rhinitis comprises: an independent layer containing montelukast or a pharmaceutically acceptable salt thereof; and an independent layer containing levocetirizine or a pharmaceutically acceptable salt thereof. The independent layers are formed in granules or a tablet. The independent layers are prepared without water or an organic solvent or the independent layers substantially do not contain water or the organic solvent. The table has a coating layer. A coating base for the coating layer is methyl cellulose, ethyl cellulose, polyvinyl alcohol, polyvinyl pyrrolidone, hydroxyl ethyl cellulose, hydroxylpropyl methyl cellulose, or a mixture thereof. The capsule is a soft capsule.
    • 目的:提供含有用于预防或治疗过敏性鼻炎和哮喘的独立的左西替利嗪层的胶囊制剂,以确保优异的产品稳定性和最大化治疗效果。 构成:用于预防或治疗过敏性鼻炎的胶囊制剂包括:含有孟鲁司特或其药学上可接受的盐的独立层; 和含有左西替利嗪或其药学上可接受的盐的独立层。 独立层以颗粒或片剂形成。 独立的层在没有水或有机溶剂的情况下制备,或独立层基本上不含水或有机溶剂。 桌子有一个涂层。 用于涂层的涂布基底是甲基纤维素,乙基纤维素,聚乙烯醇,聚乙烯吡咯烷酮,羟乙基纤维素,羟丙基甲基纤维素或它们的混合物。 胶囊是软胶囊。