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1. 发明公开

KR1020170098823A 핵산의 모노클로날 클러스터를 형성시키고 시퀀싱하기 위한 방법 및 어레이 审中-实审
标题翻译：用于形成和测序核酸单克隆簇的方法和阵列
公开(公告)号：KR1020170098823A
公开(公告)日：2017-08-30
申请号：KR1020177015817
申请日：2015-11-11
申请人： 일루미나 케임브리지 리미티드
发明人： 건더슨,케빈엘. , 바이,징웨이 , 켈링거,매튜윌리엄 , 베이얼리,존엠. , 보텔,조나단마크 , 리가티,로베르토 , 로게르트바시가루포,마리아칸델라리아 , 보야노브,보얀 , 마이싱어,클라우스
IPC分类号： B01J19/00 , C12Q1/68
CPC分类号： C12Q1/6874 , B01J19/0046 , B01J2219/00317 , B01J2219/00585 , B01J2219/00596 , B01J2219/00608 , B01J2219/00637 , B01J2219/00722 , C12Q1/6806 , C12Q1/6837 , C12Q1/6853 , C40B40/06 , C40B50/14 , C12Q2565/513 , C12Q2565/543
摘要： 본발명은특히, 마이크로어레이에서의웰에서, 고체표면상에타겟폴리누클레오티드를캡쳐하고증폭시키는방법으로서, 마이크로어레이가 a) 적어도하나의웰, 웰을둘러싸는표면, 및내부웰 표면을포함하는기판, b) 내부웰 표면을덮고적어도하나의제1 캡쳐프라이머쌍을포함하는제1 층, 및 c) 제1 층및 웰을둘러싸는표면을덮는제2 층을포함할수 있는방법에관한것이다. 대안적으로, 마이크로어레이는 a) 적어도하나의웰, 웰을둘러싸는표면및 내부웰 표면을포함하는기판, 및 b) 내부웰 표면을덮고적어도하나의제1 캡쳐프라이머쌍 및적어도하나의제2 캡쳐프라이머쌍을포함하는층을포함할수 있다. 특히, 웰에서핵산의모노클로날집단을생성시키는데역학적배제증폭이사용된다. 본출원은또한, a) 하나이상의고정된주형핵산을형성시키기위해복수의고정된캡쳐프라이머를포함하는기판을복수의주형핵산과접촉시키되, 복수의고정된캡쳐프라이머가 3'-종결유니버셜캡쳐영역 Y를포함하는제1의복수의프라이머, 예를들어, 프라이머 P5, 및 3'-종결유니버셜캡쳐영역 Z를포함하는제2의복수의프라이머, 예를들어, 프라이머 P7을포함하며, 각주형핵산이 5'-종결및 3'-종결유니버셜캡쳐영역 Y 또는 Z에의해측면배치되고하나이상의예를들어, SapI, 제한사이트, 및하나이상의제한사이트와 3'-종결유니버셜캡쳐영역사이의타겟-특이적캡쳐영역을포함하고, b) 하나이상의고정된캡쳐프라이머를확장시키는것을포함하는고정된캡쳐프라이머를개질시키는방법을기술한다. 마지막으로, 본출원은 a) 복수의상이한고정된시드핵산을형성시키기위해복수의고정된캡쳐프라이머를포함하는기판을복수의상이한시드핵산과접촉시키고, b) 복수의상이한고정된시드핵산중 둘이상에대해상보적인복수의상이한고정된확장생성물을형성시키기위해고정된캡쳐프라이머들중 둘이상을확장시키고, c) 활성화된캡쳐프라이머를형성시키기위해복수의상이한고정된확장생성물들중 하나의고정된확장생성물을활성화시키는것을포함하는, 고정된캡쳐프라이머를개질시키는방법을기술한다.
摘要翻译：基板本发明的用于包括作为用于捕获和扩增靶多核苷酸在固体表面上的方法，该微阵列上）围绕所述至少一个井，所述井具有表面，并且在阱eseoui具体地，微阵列上的内壁面，b）覆盖内井表面且包含至少一个第一捕获引物对的第一层，以及c）覆盖第一层和围绕井的表面的第二层。可选地，微阵列是）围绕所述至少一个井，所述井具有表面，并且包括内壁表面的基底，以及b）所述阱覆盖所述表面上的至少一个第一个捕获引物对和至少一个第二内以及包含捕获引物对的层。具体而言，表皮排除扩增用于在孔中产生核酸的单克隆群体。本申请也是，a）一种或多种sikidoe包括多个固定的捕获引物，以形成在与所述多个模板核酸，多个固定捕获引物3'端的通用捕获区域的接触的固定的模板核酸的基板例如，引物P5和包含3'末端通用捕获区Z的第二服装号引物，例如引物P7，其中棱柱形核酸为5 “端和3'端的通用捕获区域Y侧之间的目标或由Z设置并且含有至少一个示例中，SAPI，限制性位点，和至少一个限制性位点和3'端的通用捕获特定区域捕获区域，和b）扩增一个或多个固定的捕获引物。最后，无论是本申请的是a）使包含多个固定捕获引物，以形成多个不同的固定的种子的核酸和多个不同的种子的核酸的衬底，b）多个不同的固定的种子的核酸的至少，并且延伸所述至少两个所捕获的引物固定到形成互补多个不同的固定延长产品的，c）多个不同的固定延伸产物的固定以形成活化的捕获引物 Lt引物，引物，

2. 发明公开

KR1020090034571A 감광성 물질의 코팅을 이용한 폴리머 어레이의 제조 방법 无效
标题翻译：通过使用光敏剂涂层制备聚合物阵列的方法
公开(公告)号：KR1020090034571A
公开(公告)日：2009-04-08
申请号：KR1020070099877
申请日：2007-10-04
申请人： 삼성전자주식회사
发明人： 유창은 , 지성민
IPC分类号： G03F7/16
CPC分类号： B01J19/0046 , B01J2219/00432 , B01J2219/00439 , B01J2219/00529 , B01J2219/00596 , B01J2219/00608 , B01J2219/00659 , B01J2219/00675 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y30/00 , C40B50/14
摘要： A method for preparing a polymer array and a method for cutting a photolabile protecting group are provided to effectively manufacture a polymer array with less exposure energy by photolithography. A method for preparing a polymer array comprises the steps of: (i) reacting a monomer containing a photolabile protecting group on the surface of a substrate, and fixing the monomer on the substrate; (ii) coating the surface fixed with the monomer with the solution containing a photosensitive material and coating material; (iii) cutting the photolabile protecting group from the monomer by performing selectively electromagnetic irradiation to specific site on the surface of the substrate coated with the photosensitive material and coating material; (iv) exposing the monomer cut with the photolabile protecting group by electromagnetic irradiation of (iii) step; (v) reacting the monomer cut with the photolabile protecting group and the monomer containing the photolabile protecting group and connecting them; and (vi) repeating the (ii) ~ (v) step.
摘要翻译：提供了制备聚合物阵列的方法和切割光不稳定保护基团的方法，以通过光刻技术有效地制造具有较少曝光能量的聚合物阵列。制备聚合物阵列的方法包括以下步骤：（i）使含有光不稳定保护基团的单体在基材表面上反应，并将单体固定在基材上; （ii）用含有感光材料和涂料的溶液涂覆用单体固定的表面; （iii）通过对涂覆有感光材料和涂层材料的基材的表面上的特定部位进行选择性电磁辐射，将光不稳定保护基从单体切割; （iv）通过（iii）步骤的电磁辐射暴露用光不稳定保护基切割的单体; （v）使单体切割与光不稳定保护基与含有光不稳定保护基的单体反应并连接; 和（vi）重复（ii）〜（v）步骤。

3. 发明公开

KR1020050062639A 구조적으로 결정된 금속 구조체 및 그의 용도 无效
标题翻译：结构确定的金属构造和应用
公开(公告)号：KR1020050062639A
公开(公告)日：2005-06-23
申请号：KR1020057007332
申请日：1996-06-06
申请人： 로메드 인코포레이티드
发明人： 샤르마슈브디.
IPC分类号： G01N33/68 , G01N33/53 , A61K51/00
CPC分类号： C40B30/04 , A61K51/0497 , A61K51/08 , A61K51/082 , A61K51/083 , A61K51/086 , A61K51/088 , A61K2121/00 , A61K2123/00 , C40B40/16 , C40B50/06 , C40B50/14
摘要： A metallo-construct, which may be a peptide, is provided for use as a biological, therapeutic, diagnostic imaging, or radiotherapeutic agent, and for use in library or combinatorial chemistry methods. The construct has a conformationally constrained global secondary structure obtained upon complexing with a metal ion. The peptide constructs are of the general formula R1-X-R2, wherein X is a plurality of amino acids and includes a complexing backbone for complexing metal ions, so that substantially all of the valences of the metal ion are satisfied upon complexation of the metal ion with X, resulting in a specific regional secondary structure forming a part of the global secondary structure; and where R1 and R2 each include from 0 to about 20 amino acids, the amino acids being selected so that upon complexing the metal ion with X at least a portion of either R1 or R2 or both have a structure forming the balance of the conformationally constrained global secondary structure. All or a portion of the global secondary structure, which may be sychnologic or rhegnylogic, may form a ligand or mimic a known biological- function domain. The construct has substantially higher affinity for its target upon labeling with a metal ion.
摘要翻译：提供可以是肽的金属构建体用作生物，治疗，诊断成像或放射治疗剂，并用于文库或组合化学方法。该构型具有在与金属离子络合时获得的构象约束的全局二级结构。肽构建体具有通式R 1 -X-R 2，其中X是多个氨基酸，并且包括用于络合金属离子的络合主链，使得当金属络合时，金属离子的几乎所有价态都得到满足离子与X，导致特定的区域二级结构形成全球二级结构的一部分; 并且其中R 1和R 2各自包含0至约20个氨基酸，所述氨基酸被选择，使得当金属离子与X配位时，R 1或R 2或两者的至少一部分具有形成构象约束的平衡的结构全球二级结构。全部或部分全球二级结构（可能是系统性或流行性的）可能形成配体或模拟已知的生物功能结构域。该构建体在用金属离子标记时对其靶具有显着更高的亲和力。

4. 发明公开

KR1020010001577A 고분자 광산발생제를 이용한 올리고펩티드 핵산 탐침의 제조방법 无效
标题翻译：使用聚合光电发生器合成寡核苷酸核酸探针的方法
公开(公告)号：KR1020010001577A
公开(公告)日：2001-01-05
申请号：KR1019990020899
申请日：1999-06-07
申请人： 삼성전자주식회사
发明人： 김민환 , 김도윤 , 문봉석 , 박재찬
IPC分类号： C12Q1/68
CPC分类号： B82Y30/00 , B01J2219/00432 , B01J2219/00497 , B01J2219/00527 , B01J2219/00529 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00675 , B01J2219/00711 , B01J2219/00729 , C07B2200/11 , C07K14/003 , C40B50/14 , C40B60/14 , Y02P20/55
摘要： PURPOSE: A method for synthesizing an oligopeptide nucleic acid probe on a solid matrix using a polymeric photoacid generator is provided which has highly simplified steps and which can effectively synthesize the heavy ionic oligopeptide nucleic acid probe compared with a conventional method such as a photoresist (PR) method and a photoacid patterned array (PPA) method used in the production of biochip. CONSTITUTION: The method for synthesizing the oligopeptide nucleic acid probe on the solid matrix using the polymeric photoacid generator comprises the steps of : (1) attaching a linker that is masked with a protecting group unstable to an acid, to the solid matrix treating surface thereof; (2) coating the solid matrix with the polymeric photoacid generator; (3) exposing the coated solid matrix to light and generating the acid to remove the protecting group unstable to the acid; (4) binding the solid matrix unmasking protecting group to each monomer of the peptide nucleic acid masked with a protecting group unstable to the acid; and (5) removing the residual polymeric photoacid generator in reaction and carrying out from step (2) to step (5) repeatedly to synthesize the desired length of the oligopeptide nucleic acid probe.
摘要翻译：目的：提供使用聚合物光酸产生剂在固体基质上合成寡肽核酸探针的方法，其具有非常简化的步骤，并且可以有效地合成重离子寡肽核酸探针，与常规方法如光致抗蚀剂（PR ）方法和用于生产生物芯片的光致酸图案阵列（PPA）方法。构成：使用聚合物光酸发生剂在固体基质上合成寡肽核酸探针的方法包括以下步骤：（1）将对于酸不稳定的保护基掩蔽的接头连接到其固体基质处理表面上 ; （2）用聚合物光酸发生剂涂覆固体基质; （3）将涂覆的固体基质曝光，产生酸以除去对酸不稳定的保护基团; （4）将固体基质未掩蔽保护基与用酸不稳定的保护基掩蔽的肽核酸的每个单体结合; 和（5）反应中除去残留的聚合物光酸产生剂并重复进行步骤（2）至步骤（5）以合成所需长度的寡肽核酸探针。

5. 发明公开

KR1020000057427A 광자 및 전자 용품을 위한 친화성 자가-어셈블리 시스템 및 디바이스 失效
标题翻译：基于自适应的自组装系统和用于光电和电子应用的设备
公开(公告)号：KR1020000057427A
公开(公告)日：2000-09-15
申请号：KR1019997005013
申请日：1997-11-26
申请人： 나노트로닉스, 인크. , 더 리전트 오브 더 유니버시티 오브 캘리포니아
发明人： 헬러,마이클,제이. , 케이블,제프리,엠. , 에세너,사딕,씨.
IPC分类号： H01L25/16
CPC分类号： G06N3/002 , B01J19/0046 , B01J19/0093 , B01J2219/00315 , B01J2219/00317 , B01J2219/00497 , B01J2219/00527 , B01J2219/00529 , B01J2219/00536 , B01J2219/00545 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00653 , B01J2219/00659 , B01J2219/00686 , B01J2219/00689 , B01J2219/00707 , B01J2219/00711 , B01J2219/00713 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725 , B01J2219/00731 , B01L3/502707 , B01L3/502715 , B01L3/502761 , B01L3/5085 , B01L2200/025 , B01L2200/0663 , B01L2200/12 , B01L2300/0636 , B01L2300/0645 , B01L2400/0421 , B82B3/00 , B82Y5/00 , B82Y10/00 , B82Y20/00 , B82Y30/00 , B82Y40/00 , C07B2200/11 , C07H21/00 , C07K1/04 , C07K1/045 , C07K1/047 , C12Q1/6813 , C12Q1/6816 , C12Q1/6818 , C12Q1/6825 , C12Q1/6837 , C40B40/06 , C40B40/08 , C40B40/10 , C40B40/12 , C40B50/14 , C40B60/14 , C40B70/00 , G01N33/54366 , G02B6/1225 , G06N3/061 , G06N3/123 , G11B7/0037 , G11B7/0045 , G11B7/00455 , G11B7/005 , G11B7/0052 , G11B7/24 , G11B7/244 , G11C13/0014 , G11C13/0019 , G11C13/04 , H01L21/7806 , H01L24/95 , H01L25/16 , H01L25/50 , H01L51/0093 , H01L51/0595 , H01L2224/95085 , H01L2224/95145 , H01L2224/95147 , H01L2924/01005 , H01L2924/01006 , H01L2924/01011 , H01L2924/01013 , H01L2924/01019 , H01L2924/0102 , H01L2924/01023 , H01L2924/01025 , H01L2924/01033 , H01L2924/01039 , H01L2924/01047 , H01L2924/01049 , H01L2924/01052 , H01L2924/01072 , H01L2924/01075 , H01L2924/01079 , H01L2924/01082 , H01L2924/01322 , H01L2924/10253 , H01L2924/10329 , H01L2924/10336 , H01L2924/12041 , H01L2924/12042 , H01L2924/14 , C12Q2565/515 , C12Q2565/607 , H01L2924/00
摘要： PURPOSE: A method is provided, which enable nanotechnology and self-assembly technology by the development of programmable self-assembling molecular construction units. CONSTITUTION: A method for the fabrication of micro scale and nanoscale devices comprises the steps of: fabricating first component devices on a first support, releasing at least one first component device from the first support, transporting the first component device to a second support, and attaching the first component device to the second support. The invention also provides for orienting a structure in an electric field, reacting affinity sequences, and assembling chromophoric structures by photoactivation.
摘要翻译：目的：提供一种通过可编程自组装分子施工单元的开发实现纳米技术和自组装技术的方法。构成：用于制造微尺度和纳米级器件的方法包括以下步骤：在第一支撑件上制造第一部件装置，从第一支撑件释放至少一个第一部件装置，将第一部件装置输送到第二支撑件;以及将第一部件装置附接到第二支撑件。本发明还提供了在电场中取向结构，使亲和序列反应，并通过光活化装配发色结构。

6. 发明公开

KR1020150109356A 고체 지지체 상의 샘플 제조법 审中-实审
标题翻译：固体支持样品制备
公开(公告)号：KR1020150109356A
公开(公告)日：2015-10-01
申请号：KR1020157018788
申请日：2014-01-08
申请人： 일루미나 케임브리지 리미티드
发明人： 곰리,니얼,안토니 , 스미스,제프리,폴
IPC分类号： C12Q1/68 , C40B50/14 , C40B50/18 , B01J19/00
CPC分类号： C12N15/1065 , B01J19/0046 , B01J2219/00286 , B01J2219/00608 , B01J2219/00722 , C12N15/1093 , C12Q1/6834 , C12Q1/6869 , C12Q1/6874 , C40B40/08 , C40B50/14 , C40B50/18 , C12Q2521/543 , C12Q2525/191 , C12Q2535/122 , C12Q2565/518
摘要： 표면에 5'-태깅된이중가닥표적 DNA의고정된라이브러리를생성하기위해고정된트랜스포사제및 트랜스포손말단을이용하는방법및 조성물이제공된다. 상기방법은대규모병렬 DNA 서열화를포함하는다양한공정에이용되는 5'- 및 3'-태깅된 DNA 단편을생성하는데유용하다.
摘要翻译：提出了使用固定化转座酶和转座子端在表面上产生5'标记的双链靶DNA的固定化文库的方法和组合物。该方法可用于产生5'和3'标记的DNA片段，用于多种方法，包括大规模并行DNA测序。

7. 发明公开

KR1020100044830A 생체분자 결합 리간드 无效
标题翻译：生物分子绑定配偶
公开(公告)号：KR1020100044830A
公开(公告)日：2010-04-30
申请号：KR1020107002734
申请日：2008-06-27
申请人： 캠브리지 엔터프라이즈 리미티드
发明人： 로우크리스토퍼로빈 , 후세인아비드 , 미맥마이클루이스 , 헤이그조나단마이클
IPC分类号： C07K5/06 , C07C309/51 , C40B40/04 , G01N33/53
CPC分类号： C07C309/51 , B01D15/3804 , B01J20/286 , B01J20/289 , B01J20/3244 , B01J2220/54 , C07K1/22 , C40B30/04 , C40B40/04 , C40B50/14 , G01N33/531 , G01N33/532 , G01N33/54353 , Y10T436/143333 , Y10T436/145555 , Y10T436/147777 , Y10T436/17 , Y10T436/200833
摘要： The invention provides biomolecule binding ligands, collections of biomolecule binding ligands, and their use in the purification of biological mixtures and in the identification of ligands having an affinity for a substance. The ligand is a compound of formula (III) or a compound of formula (IV): wherein for compounds of formula (I) one of R, R,R, Rand Ris a group comprising a linker attached to a support, and the others of R, R, R, Rand Rare independently selected from optionally substituted Calkyl, optionally substituted Cheterocyclyl or optionally substituted Caryl, and R, Rand Rare additionally selected from hydrogen, and Ris additionally further selected from-S(=O)Rand-C(=S)NRR, wherein R, Rand Rare independently optionally substituted Calkyl, optionally substituted Cheterocyclyl or optionally substituted Caryl, or, optionally, two or more of the others of R, R, R, Rand R, together with the atoms to which they are bound, may form a ring; and for compounds of formula (II) one of R, R, Rand Risa group comprising a linker attached to a support, and the others of R, R, Rand Rare independently selected optionally substituted Calkyl, optionally substituted Cheterocyclyl or optionally substituted Caryl, and R, and Rare additionally selected from hydrogen, or, optionally, two or more of the others of R, R, Rand R, together with the atomsto which they are bound, may form a ring.
摘要翻译：本发明提供了生物分子结合配体，生物分子结合配体的集合，以及它们在纯化生物混合物中的用途以及鉴定对物质具有亲和力的配体。配体是式（III）化合物或式（IV）化合物：其中对于式（I）化合物，R 1，R 2，R 3，R 3中的一个包括连接在载体上的连接体， R 1，R 3，R 3，R 3，R 3独立地选自任选取代的C 1烷基，任选取代的杂环基或任选取代的Caryl，R，R R R 2另外选自氢，Ris另外选自-S（= O） = S）NRR，其中R，R 3独立地为任选取代的C 1 -C 8烷基，任选取代的杂环基或任选取代的羧基，或任选地，其中R，R，R，R R和R 2中的两个或多个与它们可能形成戒指; 并且对于式（II）化合物，R，R，兰德Risa基团之一包含连接于载体上的连接体，其中R，R，R Rare独立地选择任选被取代的C 1 -C 4烷基，任选取代的杂环基或任选取代的羧酰基，以及 R和Rare另外选自氢，或任选地，R，R，R，R中的两个或更多个，以及它们所结合的原子团可以形成环。

8. 发明公开

KR1020080015339A 가장자리 측벽이 비활성화된 프로브 셀 액티브를 포함하는올리고머 프로브 어레이 및 그 제조 방법 无效
标题翻译：具有无活性边缘壁的探针细胞的低聚物探针阵列及其制备方法
公开(公告)号：KR1020080015339A
公开(公告)日：2008-02-19
申请号：KR1020060076900
申请日：2006-08-14
申请人： 삼성전자주식회사
发明人： 김원선 , 지성민 , 하정환 , 김경선 , 최상준 , 류만형
IPC分类号： C12Q1/68
CPC分类号： C40B40/06 , B01J19/0046 , B01J2219/00432 , B01J2219/00529 , B01J2219/00608 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00675 , B01J2219/00711 , B01J2219/00722 , B82Y30/00 , C40B30/04 , C40B50/14 , G01N33/54353 , C12Q1/6876
摘要： An oligomer probe array is provided to show increased signal to noise ratio(SNR) and decreased cross-talk, thereby increasing the accuracy of analysis. An oligomer probe array comprises: a substrate; a plurality of probe cell actives formed on the substrate, each of the probe cell actives coupled to a linker excluding the edge side wall thereof to inactivate the edge side wall; a probe cell separation region separating the plurality of probe cell active and not including a functional group coupled to the oligomer probe; and a plurality of oligomer probe coupled to the linker of the probe cell active. A method for preparing an oligomer probe array comprises the steps of: (a) providing a substrate; (b) forming a plurality of probe cell active separated by probe cell separation regions on the substrate; (c) forming partition walls having a higher thickness than that of a plurality of probe cell on the probe cell separation region; (d) after spin-coating a linker solution on the substrate, spin-drying the non-reacted linker solution and baking the remaining linker solution; and (e) removing the partition walls to allow the linker to be coupled to the region excluding the edge side wall of each of the probe cell active.
摘要翻译：提供低聚物探针阵列以显示增加的信噪比（SNR）和减少的串扰，从而提高分析的准确性。低聚物探针阵列包括：基底; 形成在所述基板上的多个探针单元活性物，所述探针单元活性物质与除了所述边缘侧壁之外的接头连接，使所述边缘侧壁失活; 分离所述多个探针细胞的探针细胞分离区域，并且不包含与所述低聚物探针连接的官能团; 和耦合到探针细胞的接头的多个低聚物探针是活性的。制备低聚物探针阵列的方法包括以下步骤：（a）提供底物; （b）在所述基板上形成由探针细胞分离区分离的多个探针细胞活性物质; （c）形成具有比所述探针细胞分离区域上的多个探针单元的厚度高的分隔壁; （d）在基底上旋涂接头溶液后，旋转未反应的接头溶液并烘烤剩余的接头溶液; 和（e）除去分隔壁以允许接头连接到除了每个探针单元的边缘侧壁以外的区域。

9. 发明公开

KR1020070072511A 올리고머 합성용 중합체성 비드 有权
标题翻译：用于低聚物合成的聚合物珠
公开(公告)号：KR1020070072511A
公开(公告)日：2007-07-04
申请号：KR1020077007357
申请日：2005-09-02
申请人： 아이오니스 파마수티컬즈, 인코포레이티드 , 닛토덴코 가부시키가이샤
发明人： 라비쿠마르,바술링가 , 쿠마르,라주,케이. , 모리,켄지로우 , 코니시,타츠야 , 마츠나와,아야코 , 마츠무라,타케오 , 키타우라,치에코 , 자오,강
IPC分类号： C08F2/32 , C08F2/36 , C08F255/00 , C08J3/12
CPC分类号： C40B50/14 , B01J2219/00454 , B01J2219/00497 , B01J2219/005 , B01J2219/00722 , C07H21/00 , C08F2/18 , C08F212/08 , C08F212/12 , C08F212/14 , C08F212/36 , Y10T428/2982 , C08F2/20
摘要： The present invention provides solid support media for use in oligomer synthesis, methods of producing the media, and methods of using the media. In some embodiments, the processes of the invention comprise (a) providing an organic phase comprising an olefin monomer, a cross-linker, a functionalizing reagent and an initiator; and (b) contacting the organic phase with an aqueous phase under conditions of time and temperature effective to form the polymeric bead.
摘要翻译：本发明提供用于低聚物合成的固体支持介质，制备该介质的方法以及使用该介质的方法。在一些实施方案中，本发明的方法包括（a）提供包含烯烃单体，交联剂，官能化试剂和引发剂的有机相; 和（b）在有效形成聚合物珠粒的时间和温度的条件下使有机相与水相接触。

10. 发明公开

KR1020060120033A 수소 저장 조성물 및 이것의 제조 방법 无效
标题翻译：氢储存组合物及其制备方法
公开(公告)号：KR1020060120033A
公开(公告)日：2006-11-24
申请号：KR1020067006906
申请日：2004-09-30
申请人： 제너럴 일렉트릭 캄파니
发明人： 타운센드수잔홀트 , 미니어윌리엄폴 , 자오지-쳉 , 레몬존 , 브루어루크나타니알 , 리즈쎈비크잡토마스
IPC分类号： C01B3/00 , B01J19/00 , C01B6/21 , C01B6/00
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/00313 , B01J2219/00495 , B01J2219/00585 , B01J2219/00596 , B01J2219/00659 , B01J2219/00664 , B01J2219/00675 , B01J2219/00716 , B01J2219/00745 , B01J2219/00752 , C01B3/001 , C01B3/0078 , C01B6/21 , C01B6/23 , C01B6/24 , C40B40/18 , C40B50/14 , C40B60/14 , Y02E60/325 , Y02E60/327
摘要： Disclosed herein is a method for making a combinatorial library comprising disposing on a substrate comprising silicon, graphite, boron, boron carbide, boron nitride, aluminum, germanium, silicon nitride, silicon carbide or silicon boride at least one reactant, wherein the reactants are lithium, magnesium, sodium, potassium, calcium, aluminum or a combination comprising at least one of the foregoing reactants; heat treating the - substrate to create a diffusion multiple having at least two phases; contacting the diffusion multiple with hydrogen; detecting any absorption of hydrogen; and/or detecting any desorption of hydrogen.
摘要翻译：本文公开了一种制备组合文库的方法，包括在包含硅，石墨，硼，碳化硼，氮化硼，铝，锗，氮化硅，碳化硅或硅化硼的至少一种反应物的基底上设置，其中反应物为锂镁，钠，钾，钙，铝或包含至少一种上述反应物的组合; 热处理衬底以产生具有至少两相的扩散倍数; 使扩散倍数与氢接触; 检测氢的任何吸收; 和/或检测氢的任何解吸。

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