会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 5. 发明授权
    • 자동화 이중 온라인 다기능 액체크로마토그래피 장치
    • 自动双线性多功能液相色谱装置
    • KR101120944B1
    • 2012-03-05
    • KR1020110061856
    • 2011-06-24
    • 고려대학교 산학협력단
    • 이상원형석원이정화김경철문동기
    • G01N30/20G01N30/22G01N30/24G01N30/02
    • G01N30/468B01D15/325G01N30/20G01N2030/009
    • 본발명은자동화이중온라인다기능액체크로마토그래피장치에관한것으로서, 분석대상이되는시료가로딩되는시료유입밸브; 제1 고체상추출칼럼및 제1 역상액체크로마토그래피칼럼과유체연통되는, 제1 트랩밸브; 제2 고체상추출칼럼및 제2 역상액체크로마토그래피칼럼과유체연통되는, 제2 트랩밸브; 유입되는유체를상기제1 트랩밸브또는상기제2 트랩밸브로선택적으로각각배출시키는제1 분리밸브및 제2 분리밸브; 상기시료유입밸브에서상기제1, 제2 트랩밸브로향하는유로에위치하며, 시료분리칼럼이연결되는다기능선택밸브; 및상기시료유입밸브로부터유출되는유체를상기다기능선택밸브, 상기제1 트랩밸브, 또는상기제2 트랩밸브로선택적으로공급하는연결밸브;를포함하며, 본발명에따른자동화이중온라인다기능액체크로마토그래피장치를이용하면탈염과정및 시료농축이가능한 1차원분리기능및 시료분리칼럼을통과시켜탈염과정및 시료농축의효율을높일수 있는 2차원분리기능과, 온라인소화기능을수행할수 있으며, 이와함께매회반복되는실험사이에소요되는칼럼평형화시간동안실험을멈추어야하는휴지시간(dead time)을최소화하여실험속도를증가시킬수 있다.
    • 6. 发明公开
    • 단백질 분리용 나노입자, 그 제조 방법 및 이를 이용한 단백질 분리 정제 방법
    • 用于分离蛋白质的纳米颗粒,其制备方法和使用其分离和纯化蛋白质的方法
    • KR1020100070171A
    • 2010-06-25
    • KR1020080128786
    • 2008-12-17
    • 고려대학교 산학협력단
    • 이상원이광렬허지영이연지
    • B82B3/00C07H1/06C07K1/14
    • C07K1/14B82Y5/00B82Y15/00C07H1/06
    • PURPOSE: A nanoparticle for isolating proteins is provided to isolate and purify GST-tagged protein using a magnetic nanoparticle on which glutathione is conjugated. CONSTITUTION: A nanoparticle for isolating GST-tagged protein has a magnetic nanoparticle surface on which glutathione group is conjugated. The magnetic nanoparticle is conjugated with a silica layer. The glutathione group is conjugated with 2-pyridyl disulfide which is bound to the silica layer. A method for manufacturing the nanoparticle for isolating the GST tagged protein comprises: a step of coating the surface of magnetic nanoparticle with the silica layer; a step of binding 2-pyridyl disulfide group to the silica layer; and a step of binding glutathione group to 2-pyridyldisulfide group.
    • 目的:提供用于分离蛋白质的纳米颗粒,以使用其上结合有谷胱甘肽的磁性纳米颗粒分离和纯化GST标记的蛋白质。 构成:用于分离GST标记的蛋白质的纳米颗粒具有结合有谷胱甘肽基团的磁性纳米颗粒表面。 磁性纳米颗粒与二氧化硅层共轭。 谷胱甘肽基与与二氧化硅层结合的2-吡啶基二硫键缀合。 用于制造用于分离GST标记蛋白的纳米颗粒的方法包括:用二氧化硅层涂覆磁性纳米颗粒的表面的步骤; 将二吡啶基二硫键与二氧化硅层结合的步骤; 和将谷胱甘肽基团结合到2-吡啶基二硫基的步骤。
    • 7. 发明公开
    • 펩티드 분리용 나노입자, 그 제조방법 및 이를 이용한 펩티드 분리방법
    • 用于分离肽的纳米颗粒,其制备方法和使用其分离肽的方法
    • KR1020090056868A
    • 2009-06-03
    • KR1020080119056
    • 2008-11-27
    • 고려대학교 산학협력단
    • 이상원이광렬이제선허지영김민식이연지
    • B82B1/00B82B3/00B82Y5/00
    • B82Y5/00G01N33/54333G01N33/587Y10T428/2982
    • A nanoparticle for peptide separation and a preparation method thereof are provided to rapidly and selectively separate desired peptide through a simple process owing to magnetic nanoparticles of which the surface is coupled with a first functional group which selectively reacts to a certain peptide. A nanoparticle for peptide separation has the magnetic surface which is coupled with a first functional group having thiol selectivity. The nanoparticle for peptide separation selectively couples with the peptide including cysteine. The first functional group includes 2-pyridyl disulfide residual group. The magnetic nanoparticle is coated with a silica layer. The first functional group is bonded with the silica layer. The surface of the nanoparticle additionally contains a second functional group which prevents the coherence of the nanoparticles.
    • 提供了用于肽分离的纳米颗粒及其制备方法,通过简单的方法快速且有选择地分离所需的肽,因为磁性纳米颗粒与表面与选择性地与特定肽反应的第一官能团偶联。 用于肽分离的纳米颗粒具有与具有硫醇选择性的第一官能团偶联的磁性表面。 用于肽分离的纳米颗粒选择性地与包括半胱氨酸的肽结合。 第一官能团包括2-吡啶基二硫化物残基。 磁性纳米颗粒涂覆有二氧化硅层。 第一官能团与二氧化硅层结合。 纳米颗粒的表面还含有防止纳米颗粒的相干性的第二官能团。
    • 8. 发明授权
    • 초고압 이중 온라인 고체상 추출 및 역상 액체크로마토그래피 장치
    • 超高压双重在线固相萃取/毛细管反相液相色谱系统
    • KR100757512B1
    • 2007-09-11
    • KR1020060113175
    • 2006-11-16
    • 고려대학교 산학협력단
    • 이상원형석원
    • G01N30/88
    • G01N30/468G01N30/34G01N30/36G01N2030/347G01N30/06G01N30/14G01N30/7233G01N30/89G01N2030/062
    • An ultra high pressure dual on-line solid phase extraction and reverse phase liquid chromatography system is provided to improve a test rate by minimizing a dead time for equilibration, to inject a sample rapidly, to allow on-line sample desalting and concentrating steps and to show high reproducibility. A chromatography system comprises a sample injection valve(100) for a 1st solvent and a sample; a column selection valve(200) for selecting a 1st column valve or a 2nd column valve for the injected sample; a 1st column valve(300) which is in fluid communication with a 1st solid phase extraction column and a 1st reverse liquid chromatography column(308); a 2nd column valve(400) which is in fluid communication with a 2nd solid phase extraction column and a 2nd reverse liquid chromatography column(408); a solvent selection valve(500) which is in fluid communication with the 1st and 2nd column valve to supply thereto the 1st solvent or a mixture of the 1st solvent and a 2nd solvent; a 2nd solvent injection valve(600) for the 1st and 2nd solvent, which is in communication with a solvent mixer(700); a 2nd solvent feeding pump for supplying the 2nd solvent to the 2nd solvent injection valve; and a 1st solvent feeding pump for supplying the 1st solvent to the sample injection valve, the 2nd solvent injection valve and the solvent selection valve.
    • 提供超高压双重在线固相萃取和反相液相色谱系统,以通过最小化平衡的死时间,快速注射样品,以允许在线样品脱盐和浓缩步骤,以及 显示出高重现性。 色谱系统包括用于第一溶剂和样品的样品注入阀(100); 用于选择所述注入样品的第一柱阀或第二柱阀的柱选择阀(200) 与第一固相萃取塔和第一反相液相色谱柱(308)流体连通的第一柱阀(300); 与第二固相萃取塔和第二反相液相色谱柱(408)流体连通的第二柱阀(400); 溶剂选择阀(500),其与第一和第二柱阀流体连通,以向第一溶剂或第一溶剂和第二溶剂的混合物供应第一溶剂; 用于与溶剂混合器(700)连通的第一和第二溶剂的第二溶剂注入阀(600); 用于将第二溶剂供应到第二溶剂注入阀的第二溶剂供给泵; 以及用于向样品注射阀,第二溶剂注入阀和溶剂选择阀供应第一溶剂的第一溶剂供给泵。
    • 10. 发明授权
    • 발광소자 및 조명시스템
    • KR102237134B1
    • 2021-04-08
    • KR1020140129973
    • 2014-09-29
    • 엘지이노텍 주식회사고려대학교 산학협력단
    • 이상원김지현정영훈
    • H01L33/22F21Y115/10
    • 실시예에따른발광소자는제 1 도전형반도체층과, 상기제 1 도전형반도체층상에배치된활성층과, 상기활성층상에배치된제 2 도전형반도체층을포함하는발광구조물; 및상기발광구조물의광추출영역상에배치된광추출구조;를포함하고, 상기발광구조물은무극성질화물반도체를포함하며, 상기광추출구조는복수의돌출부를포함하는요철구조를가지며, 상기복수의돌출부는삼각기둥, 사각기둥또는다각기둥중 적어도어느하나의형상을갖는것을특징으로한다. 다른측면에서실시예는제 1 도전형반도체층과, 상기제 1 도전형반도체층상에배치된활성층과, 상기활성층상에배치된제 2 도전형반도체층을포함하는발광구조물; 및상기발광구조물의광추출영역상에배치된광추출구조;를포함하고, 상기발광구조물은반극성질화물반도체를포함하며, 상기광추출구조는복수의돌출부를포함하는요철구조를가지며, 상기복수의돌출부는삼각뿔, 사각뿔, 다각뿔또는원뿔중 적어도어느하나의형상을갖는것을특징으로한다.