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1. 发明专利

JP2008167721A Method for producing polyunsaturated fatty acid and lipid containing the same 有权
标题翻译：生产聚氨酯脂肪酸的方法和含有脂肪酸的脂肪
公开(公告)号：JP2008167721A
公开(公告)日：2008-07-24
申请号：JP2007006293
申请日：2007-01-15
申请人： Suntory Ltd , サントリー株式会社
发明人： KATANO KENJI , KAWASHIMA HIROSHI
IPC分类号： C12P7/64 , A23L1/30 , C12N1/20 , C12R1/01
CPC分类号： C12P7/6427 , A23K20/158 , A23K50/40 , A23K50/80 , A23L33/12 , C11B1/10 , C11B3/00 , C12P7/6472
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a polyunsaturated fatty acid (PUFA) and a lipid containing the acid and to provide a microorganism containing a PUFA and its use. SOLUTION: The method for producing a polyunsaturated fatty acid (PUFA) and a lipid containing the acid comprises the culture of a microorganism producing arachidonic acid (ARA) and/or dihomo-γ-linolenic acid (DGLA) and contains one or more of the following steps (a) to (c); (a) a step to add an organic acid to the medium in an amount of 0.01-5 w/v% after starting the main cultivation, (b) a step to control the pH of the medium in a manner to increase the pH within a cultivation effective range, and (c) a step to add a metal sulfate to the main culture medium in an amount of 0.01-0.5 w/w%. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：待解决的问题：提供一种制备多不饱和脂肪酸（PUFA）和含有酸的脂质的方法，提供含有PUFA的微生物及其用途。解决方案：制备多不饱和脂肪酸（PUFA）和含有酸的脂质的方法包括产生花生四烯酸（ARA）和/或二硫-γ-亚麻酸（DGLA）的微生物的培养物，并含有一种或多种以下步骤（a）至（c）; （a）在开始主培养后以0.01-5w / v％的量向培养基中加入有机酸的步骤，（b）以增加pH值的方式控制培养基的pH的步骤培养有效范围，以及（c）以0.01-0.5w / w％的量向主培养基中添加金属硫酸盐的步骤。版权所有（C）2008，JPO＆INPIT

2. 发明专利

JP2006061021A Method for producing triglyceride formed out of three residues of highly unsaturated fatty acid of one kind and utilization of the same 审中-公开
标题翻译：生产由三种高度不饱和脂肪酸形成的三羧酸的方法及其利用
公开(公告)号：JP2006061021A
公开(公告)日：2006-03-09
申请号：JP2004244218
申请日：2004-08-24
申请人： Suntory Ltd , サントリー株式会社
发明人： KAWASHIMA HIROSHI , SAKURATANI EIJI , OGAWA JUN , SHIMIZU AKIRA
IPC分类号： C12P7/64 , C12N1/14 , C12R1/645
CPC分类号： A23K20/158 , A23D9/00 , A23L2/52 , A23L33/115 , C11B1/10 , C12P7/6472
摘要： PROBLEM TO BE SOLVED: To provide fats and oils containing a new triglyceride, to provide a method for producing the same, and to provide a microorganism used for producing the same. SOLUTION: In this method for producing the fats and oils so composed that a ratio of the triglyceride formed by combining three hydroxy groups of a glycerol with highly unsaturated fatty acids of the same kind is 20 wt% or more based on an total amount of triglycerides, the microorganism capable of producing the fats and oils is cultured and the fats and oils are collected, when desired. Thus, the fats and oils which are obtained by the method and the method for producing the fats and oils are provided, respectively. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：提供含有新甘油三酯的脂肪和油，以提供其制备方法，并提供用于制备该甘油三酯的微生物。解决方案：在这种生产油脂的方法中，通过将甘油三种羟基与相同种类的高度不饱和脂肪酸组合而形成的甘油三酯的比例为20重量％以上培养甘油三酯的量，能够生产脂肪和油的微生物，并且当需要时收集脂肪和油。因此，分别提供通过该方法获得的脂肪和油以及油脂的制造方法。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2006056795A Skin cosmetic and food and drink comprising 6-o-pufa ascorbic acid ester 审中-公开
标题翻译：皮肤化妆品和饮料，包含6-O-PUFA抗坏血酸酯
公开(公告)号：JP2006056795A
公开(公告)日：2006-03-02
申请号：JP2004237942
申请日：2004-08-18
申请人： Suntory Ltd , サントリー株式会社
发明人： FUKAMI JIICHI , KAWASHIMA HIROSHI , ONO YOSHIKO
IPC分类号： A61K8/00 , A23L1/302 , A23L2/52 , A61K8/67 , A61Q19/00
CPC分类号： A61K8/676 , A23L33/12 , A23L33/15 , A61Q5/00 , A61Q17/04 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a skin cosmetic and a food and drink comprising 6-O-PUFA (polyunsaturated fatty acid)-ascorbate.
SOLUTION: The skin cosmetic comprises a 6-O-PUFA-ascorbate represented by general formula (I): RCO-A (wherein, RCO denotes an acyl group derived from a highly unsaturated fatty acid; and A denotes a residue of ascorbic acid binding with O derived from a hydroxy group of the ascorbic acid) as a vitamin C ingredient. The skin cosmetic effectively exhibits excellent tissue or cell migration properties of the ascorbic acid and is expectable of even functionality possessed by the PUFA. The food and drink comprises the 6-O-PUFA-ascorbate represented by general formula (I).
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种皮肤化妆品和包含6-O-PUFA（多不饱和脂肪酸） - 抗坏血酸的食品和饮料。皮肤化妆品包含由通式（I）表示的6-O-PUFA-抗坏血酸盐：RCO-A（其中，RCO表示衍生自高度不饱和脂肪酸的酰基; A表示抗坏血酸与来自抗坏血酸的羟基的O结合）作为维生素C成分。皮肤化妆品有效地显示抗坏血酸的优异的组织或细胞迁移性质，并且期望PUFA具有的甚至功能性。食品和饮料包括由通式（I）表示的6-O-PUFA-抗坏血酸盐。版权所有（C）2006，JPO＆NCIPI

4. 发明专利

JP2005206476A Prophylactic or ameliorating agent for liver disease accompanied with hepatopathy 有权
标题翻译：用于肝硬化的肝病的预防或治疗药物
公开(公告)号：JP2005206476A
公开(公告)日：2005-08-04
申请号：JP2004012207
申请日：2004-01-20
申请人： Suntory Ltd , サントリー株式会社
发明人： ISHIKURA YOSHIYUKI , KAWASHIMA HIROSHI , HAMAZAKI TOMOHITO , WATANABE SHIRO
IPC分类号： A23L1/30 , A61K31/231 , A61K31/232 , A61P1/16 , A61P35/00 , C12P7/64
CPC分类号： A61K31/232 , A23L33/12 , A61K31/231 , C12P7/6472
摘要： PROBLEM TO BE SOLVED: To provide a new prophylactic or ameliorating agent for liver diseases accompanied with hepatopathy. SOLUTION: The prophylactic or ameliorating agent for the liver diseases accompanied with the hepatopathy comprises an ω9-series unsaturated fatty acid or a compound containing the ω9-series unsaturated fatty acid as a constituent fatty acid. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种伴随肝病的肝脏疾病的新型预防或改善剂。解决方案：伴有肝病的肝脏疾病的预防或改善剂包括ω9系不饱和脂肪酸或含有ω9系不饱和脂肪酸作为构成脂肪酸的化合物。版权所有（C）2005，JPO＆NCIPI

5. 发明专利

JP2003048831A Composition having preventing and ameliorating action on symptom or disease caused by decrease in brain function 审中-公开
标题翻译：具有预防和改善由于脑功能下降引起的症状或疾病的作用的组合物
公开(公告)号：JP2003048831A
公开(公告)日：2003-02-21
申请号：JP2001235519
申请日：2001-08-02
申请人： Suntory Ltd , サントリー株式会社
发明人： AKIMOTO KENGO , KAWASHIMA HIROSHI , ONO YOSHIKO , OKAICHI HIROSHIGE , OKAICHI YOKO
IPC分类号： A23L2/38 , A23D9/00 , A23D9/007 , A23D9/013 , A23L1/00 , A23L1/30 , A23L2/52 , A61K31/202 , A61K31/232 , A61K31/557 , A61K31/66 , A61K31/683 , A61K31/7024 , A61K31/715 , A61K35/66 , A61K36/06 , A61P25/24 , A61P25/28 , A61K35/70
CPC分类号： A61K31/7024 , A23D9/00 , A23D9/007 , A23D9/013 , A23L2/52 , A23L33/12 , A23V2002/00 , A61K31/202 , A61K31/232 , A61K31/557 , A61K31/66 , A23V2250/1862
摘要： PROBLEM TO BE SOLVED: To obtain a composition having preventing or ameliorating action on symptoms or diseases caused by decease in brain functions. SOLUTION: This composition comprises arachidonic acid and/or a compound composed of arachidonic acid as a constituent fatty acid, especially an arachidonic acid ester, a triglyceride, a phospholipid or a glycolipid in which a part or the whole of a constituent fatty acid is arachidonic acid as an active ingredient.
摘要翻译：要解决的问题：获得对脑功能衰竭引起的症状或疾病具有预防或改善作用的组合物。解决方案：该组合物包括花生四烯酸和/或由花生四烯酸作为构成脂肪酸组成的化合物，特别是花生四烯酸酯，甘油三酯，磷脂或糖脂，其中一部分或全部构成脂肪酸是花生四烯酸酸作为活性成分。

6. 发明专利

JP2007209272A Method for producing phospholipid containing long chain highly unsaturated fatty acid produced by microbial fermentation as component 审中-公开
标题翻译：生产含微生物发酵作为成分的长链高度不饱和脂肪酸的磷脂的制备方法
公开(公告)号：JP2007209272A
公开(公告)日：2007-08-23
申请号：JP2006033657
申请日：2006-02-10
申请人： Suntory Ltd , サントリー株式会社
发明人： SHIRAISHI AKIKO , KAWASHIMA HIROSHI
IPC分类号： C12P9/00
CPC分类号： C12P7/6481 , C12P9/00 , C12P13/001 , C12P13/06
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a phospholipid containing a long chain highly unsaturated fatty acid as a component.
SOLUTION: The phospholipid is obtained by cultivating Mortierella alpina of a microorganism belonging to genus Mortierella on a condition of accumulating the phospholipid in microbes of the microorganism, wherein the composition ratio of isopalmitic acid of a branched fatty acid is ≤5% based on the total amount of the fatty acids contained as constituents of all phospholipids contained in the culture products. As the phospholipids obtained by the method, glycerophospholipids such as phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine, phosphatidylinositol, phosphatidic acid and cardiolipin are listed.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：待解决的问题：提供一种制备含有长链高度不饱和脂肪酸作为组分的磷脂的方法。解决方案：通过在微生物的微生物中积聚磷脂的条件下培养属于被孢霉属的微生物的被孢霉属（Mortierella alpina）获得磷脂，其中支链脂肪酸的异棕榈酸的组成比为≤5％关于包含在培养产物中的所有磷脂的成分的脂肪酸的总量。作为通过该方法得到的磷脂，列举了磷脂酰胆碱，磷脂酰丝氨酸，磷脂酰乙醇胺，磷脂酰肌醇，磷脂酸，心磷脂等甘油磷脂。版权所有（C）2007，JPO＆INPIT

7. 发明专利

JP2006306813A Mast cell increase inhibitor 审中-公开
标题翻译： MAST CELL INCRIASE INHIBITOR
公开(公告)号：JP2006306813A
公开(公告)日：2006-11-09
申请号：JP2005133271
申请日：2005-04-28
申请人： Suntory Ltd , サントリー株式会社
发明人： TATEISHI NORIFUMI , KAWASHIMA HIROSHI
IPC分类号： A61K31/202 , A23L1/30 , A61K31/232 , A61P11/00 , A61P11/06 , A61P17/00 , A61P17/04 , A61P17/06 , A61P27/02 , A61P27/14 , A61P27/16 , A61P35/00 , A61P37/08 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a new composition effective for preventing or treating diseases related to an increase in mast cell count. SOLUTION: The composition effective for preventing or treating diseases related to an increase in its cell count contains dihomo-γ-linolenic acid (DGLA). COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供有效预防或治疗与肥大细胞计数增加有关的疾病的新组合物。解决方案：用于预防或治疗与细胞计数增加有关的疾病的组合物含有二高γ-亚麻酸（DGLA）。版权所有（C）2007，JPO＆INPIT

8. 发明专利

JP2006306812A Acidocyte infiltration inhibitor 审中-公开
标题翻译：酸洗剂浸润抑制剂
公开(公告)号：JP2006306812A
公开(公告)日：2006-11-09
申请号：JP2005133264
申请日：2005-04-28
申请人： Suntory Ltd , サントリー株式会社
发明人： TATEISHI NORIFUMI , KAWASHIMA HIROSHI
IPC分类号： A61K31/202 , A23L1/30 , A61K9/08 , A61K9/20 , A61K9/48 , A61K31/232 , A61P1/04 , A61P11/00 , A61P11/06 , A61P17/00 , A61P17/06 , A61P37/08 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a new composition effective for preventing or treating diseases related to the infiltration of acidocyte or to an increase of its cell count. SOLUTION: The composition effective for preventing or treating diseases related to the infiltration of acidocyte or to an increase in its cell count contains dihomo-γ-linolenic acid (DGLA). COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供有效预防或治疗与酸性细胞浸润相关的疾病或其细胞计数增加的新组合物。解决方案：用于预防或治疗与酸性细胞浸润有关的疾病或其细胞数量增加有效的组合物含有二高γ-亚麻酸（DGLA）。版权所有（C）2007，JPO＆INPIT

9. 发明专利

JP2006219454A Oral agent for treatment or prevention of cutaneous disease 有权
标题翻译：口服代谢治疗或预防切除性疾病
公开(公告)号：JP2006219454A
公开(公告)日：2006-08-24
申请号：JP2005036235
申请日：2005-02-14
申请人： Suntory Ltd , サントリー株式会社
发明人： TATEISHI NORIFUMI , KAWASHIMA HIROSHI
IPC分类号： A61K31/202 , A23L1/30 , A61K31/232 , A61K31/715 , A61K38/00 , A61P17/00 , A61P17/16 , A61P27/00 , A61P37/08 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a new composition for the prevention or treatment of cutaneous diseases such as atopic dermatitis. SOLUTION: The invention provides a composition containing dihomo-γ-linolenic acid (DGLA), having preventing or treating effect on cutaneous diseases and usable as foods, medicines, etc. COPYRIGHT: (C)2006,JPO&NCIPI

10. 发明专利

JP2005336205A Agent for preventing and improving medical symptom through delayed type allergic reaction 审中-公开
标题翻译：通过延迟型过敏反应预防和改善医学症状的药剂
公开(公告)号：JP2005336205A
公开(公告)日：2005-12-08
申请号：JP2005229797
申请日：2005-08-08
申请人： Suntory Ltd , サントリー株式会社
发明人： AKIMOTO KENGO , KAWASHIMA HIROSHI , HAMAZAKI TOMOHITO , SAWAZAKI SHIGEKI
IPC分类号： A23L1/30 , A61K31/201 , A61K31/202 , A61P17/00 , A61P37/08
摘要： PROBLEM TO BE SOLVED: To provide a new agent for preventing and improving a medical symptom through a delayed type allergic reaction. SOLUTION: This agent for preventing and improving a medical symptom through a delayed type allergic reaction contains an omega 9-unsaturated fatty acid as an active ingredient. COPYRIGHT: (C)2006,JPO&NCIPI

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