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    • 7. 发明专利
    • Method for producing phosphatide salt
    • 生产磷酸盐的方法
    • JP2011160795A
    • 2011-08-25
    • JP2010173300
    • 2010-08-02
    • Lipogen Ltdリポゲン エルティディ.
    • RUTENBERG DAVID
    • C12P9/00
    • C12P7/6481C12P9/00C12P13/06
    • PROBLEM TO BE SOLVED: To provide a novel method for producing a phosphatide-salt complex.
      SOLUTION: The method for producing the phosphatide-salt complex includes steps of: using at least one raw material lecithin as a substrate; and enzymatically processing at least one raw material lecithin with phospholipase-D (PLD), racemic body or enantiomerically pure serine, or amine in an aqueous carboxylate complex solution, wherein the step of processing is performed in a single-phase reaction environment to produce the phosphatide-salt complex having a structural fatty-acid chain derived from at least one raw material lecithin. The step of processing is performed at a pH in the range of about 4.5-8.0 at a temperature in the range of about 25-60°C. The aqueous carboxylate-salt complex solution is formed from an aqueous solution of a carboxylic acid with a chain length of C2-C8 and a salt in an approximately 1:2 (weight per weight) acid-to-salt ratio.
      COPYRIGHT: (C)2011,JPO&INPIT
    • 待解决的问题:提供一种生产磷脂 - 盐复合物的新方法。 解决方案:制备磷脂 - 盐复合物的方法包括以下步骤:使用至少一种原料卵磷脂作为底物; 并在羧酸盐复合物水溶液中用磷脂酶-D(PLD),外消旋体或对映异构体纯的丝氨酸或胺酶处理至少一种原料卵磷脂,其中处理步骤在单相反应环境中进行以产生 具有衍生自至少一种原料卵磷脂的结构脂肪酸链的磷脂 - 盐配合物。 在大约25-60℃的温度下,在约4.5-8.0的pH范围内进行处理步骤。 羧酸盐水溶液配合物溶液由链长为C 2 -C 8的羧酸水溶液和约1:2(重量/重量/重量)酸 - 盐比的盐形成。 版权所有(C)2011,JPO&INPIT