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1. 发明专利

JP2009168818A Method of preserving reagent in minute flow apparatus for blood biochemical reactions, and biochemical inspection method using minute flow apparatus 审中-公开
标题翻译：用于血液生化反应的分流装置中的试剂保存方法和使用分钟流量装置的生物化学检查方法
公开(公告)号：JP2009168818A
公开(公告)日：2009-07-30
申请号：JP2009007700
申请日：2009-01-16
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： CHO YOON-KYOUNG , LIM HEE-KYUN , LEE JEONG-GUN , KIM KI-EUM , LEE SUNGHO , LEE CHAE-JOON
IPC分类号： G01N35/08 , G01N33/49 , G01N37/00
CPC分类号： B01L3/50273 , B01L2200/16 , B01L2300/0803 , B01L2300/0864 , B01L2300/087 , B01L2400/0409
摘要： PROBLEM TO BE SOLVED: To provide a method of preserving a reagent in a minute flow apparatus for blood biochemical reactions, and to provide a biochemical inspection method using the minute flow apparatus.
SOLUTION: The method of preserving the reagent in the minute flow apparatus includes the step of injecting the reagent into reaction chambers provided in the minute flow apparatus, and the step of freeze-drying the reagent in the state of being injected into the minute flow apparatus. The biochemical inspection method using the minute flow apparatus which employs the minute flow apparatus for biochemical inspections in which the reaction chambers holding the reagents for carrying out a biochemical inspection and fluid flow passages are provided, includes the step of injecting the reagents into the reaction chambers provided in the minute flow apparatus, and the step of freeze-drying the reagent in the state of being injected into the minute flow apparatus.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种在用于血液生化反应的微流量装置中保留试剂的方法，并提供使用微流量装置的生物化学检查方法。解决方案：在微流量装置中保存试剂的方法包括将试剂注入到微流量装置中所设置的反应室中的步骤，以及将试剂注入的方法冷冻干燥的步骤微流量装置。使用采用微流量装置进行生物化学检查的微流量装置的生物化学检查方法，其中容纳用于进行生物化学检查和流体流动通道的试剂的反应室包括将试剂注入反应室以及在注入微量流量装置的状态下将试剂冷冻干燥的步骤。版权所有（C）2009，JPO＆INPIT

2. 发明专利

JP2008062232A Finely floating device of centrifugal base having thermal active unit, finely floating system having the same, and method for driving finely floating system 审中-公开
标题翻译：具有热活性单元的离心底座的精细浮动装置，具有该活性单元的精细浮动系统以及用于驱动精细浮动系统的方法
公开(公告)号：JP2008062232A
公开(公告)日：2008-03-21
申请号：JP2007228426
申请日：2007-09-04
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： CHO YOON-KYOUNG , LEE JEONG-GUN , LEE BEOM SEOK , PARK SHOBEN
IPC分类号： B01J19/00 , B01J19/12 , G01N35/10 , G01N37/00
CPC分类号： F16K99/003 , B01L3/502738 , B01L2300/0806 , B01L2300/0867 , B01L2300/0887 , B01L2400/0409 , B01L2400/0677 , F16K99/0001 , F16K99/0032 , F16K99/004 , F16K2099/0084
摘要： PROBLEM TO BE SOLVED: To provide the finely floating device of a centrifugal base having a thermal active unit, a finely floating system having the same, and a method for driving the finely floating system. SOLUTION: The finely floating device 20 is provided with a rotor 21 and a finely floating structure 22, the structure 22 is disposed at the rotor 21 and provided with two base units 23 or more of mutually different distances from the center of the rotor 21 and at least one thermal active unit that causes a temperature variation, a heating particle M that radiates thermal energy around by absorbing an electromagnetic wave emitted from the outside is provided inside the unit 23. In addition, the system is provided with a rotary driving section 40, an external energy source 30, and an external energy source controlling means together with the device 20. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供具有热活性单元的离心底座的微细浮动装置，具有该活动单元的微细浮动系统以及用于驱动微细浮动系统的方法。解决方案：微浮装置20设置有转子21和微细浮动结构22，结构22设置在转子21处，并且设置有距离中心的相互不同距离的两个基座单元23或更多转子21和导致温度变化的至少一个热活性单元，在单元23内设置有通过吸收从外部发射的电磁波而散发热能的加热颗粒M.此外，该系统设置有旋转驱动部分40，外部能量源30和外部能量源控制装置与装置20一起使用。（C）2008年，JPO和INPIT

3. 发明专利

JP2008055405A Method for mixing at least two kinds of fluids in micro-fluid treating substrate using centrifugal force 有权
标题翻译：使用离心力在微流体处理基材中混合最少两种流体的方法
公开(公告)号：JP2008055405A
公开(公告)日：2008-03-13
申请号：JP2007165904
申请日：2007-06-25
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： CHO YOON-KYOUNG , LEE JEONG GUN , LEE BEOM SEOK , PARK JONG-MYEON
IPC分类号： B01F11/00 , B01J19/00
CPC分类号： B01F13/0059 , B01F11/0002 , B01F11/0014 , B01F15/0201 , B01F15/0233
摘要： PROBLEM TO BE SOLVED: To provide a method for quickly mixing at least two kinds of fluids in a micro-fluid treating substrate using a centrifugal force. SOLUTION: At least two kinds of the fluids are accommodated in a mixing chamber 15 of the micro-fluid treating substrate, the substrate 10 is alternately rotated clockwise and counterclockwise until at least the two kinds of the fluids are mixed. However, one rotational direction of the substrate is turned to the other before whirls formed in the mixing chamber are dissipated by any of the clockwise and counterclockwise rotations. In addition, one kind of fluid is accommodated in the chamber 15 of the micro-fluid treating substrate, at least one kind of fluid different from the fluid is allowed to flow with the centrifugal force from a supply chamber to the mixing chamber, thereby alternately rotating the substrate 10 clockwise and counterclockwise until the fluids are mixed. However, the rotation of the substrate is turned to the other before the whirls formed in the mixing chamber are dissipated by any of the clockwise and counterclockwise rotations. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种使用离心力在微流体处理基板中快速混合至少两种流体的方法。解决方案：至少两种流体容纳在微流体处理基板的混合室15中，基板10交替地顺时针和逆时针旋转，直到两种流体至少混合。然而，在混合室中形成的旋涡之间的任何顺时针和逆时针旋转都会消散基板的一个旋转方向。此外，一种流体被容纳在微流体处理基板的室15中，使得与流体不同的至少一种流体随着离心力从供给室流到混合室，从而交替地旋转基板10顺时针和逆时针直到流体混合。然而，在混合室中形成的旋转通过任何顺时针和逆时针旋转而消散之前，基板的旋转转向另一个。版权所有（C）2008，JPO＆INPIT

4. 发明专利

JP2007278502A Valve unit and device having the same 有权
标题翻译：阀门单元及其设备
公开(公告)号：JP2007278502A
公开(公告)日：2007-10-25
申请号：JP2007072764
申请日：2007-03-20
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： PARK JONG-MYEON , LEE JEONG-GUN , CHO YOON-KYOUNG
IPC分类号： B01L99/00 , F16K17/38 , F16K13/00 , F16K31/64 , F16K49/00 , G01N35/08
CPC分类号： F16K13/10 , B01L3/502715 , F16K31/002 , F16K31/025 , F16K99/0001 , F16K99/0019 , F16K99/0032 , F16K99/004 , F16K2099/0084 , Y10T436/2575
摘要： PROBLEM TO BE SOLVED: To provide a valve unit and a device having the valve unit improving the accuracy of opening timing. SOLUTION: The valve unit comprises a plug 60 including a phase change material in a solid state at a room temperature and fine heat-dissipating particles dispersed in the phase change material and dissipating heat by absorbing electromagnetic wave energy of electromagnetic wave radiation from the outside, and blocking a channel 55 forming a fluid passage, to cut off fluid flow, and an external energy source 70 for irradiating the plug with the electromagnetic wave. When the plug is irradiated with the electromagnetic wave from the outside, the fine heat-dissipating particles dissipate heat to melt the phase change material, thus opening the passage. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种阀单元和具有提高打开正时精度的阀单元的装置。解决方案：阀单元包括一个插塞60，它包括室温固态相变材料和分散在相变材料中的精细散热颗粒，并通过吸收电磁波辐射的电磁波来消散热量并且阻挡形成流体通道的通道55以切断流体流动，以及外部能量源70，用于用电磁波照射塞子。当从外部用电磁波照射插头时，细散热颗粒散发热量以熔化相变材料，从而打开通道。版权所有（C）2008，JPO＆INPIT

5. 发明专利

JP2008197097A Centrifugal force based microflow apparatus for dilution and microflow system comprising it 有权
标题翻译：用于渗透和微流控系统的基于离心力的微流体装置
公开(公告)号：JP2008197097A
公开(公告)日：2008-08-28
申请号：JP2008026810
申请日：2008-02-06
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： CHO YOON-KYOUNG , LEE JEONG-GUN , LEE BEOM SEOK , PARK SHOBEN , LEE YOUNG-SUN
IPC分类号： B01L99/00 , G01N35/00 , B01F11/00 , G01N35/08 , G01N37/00
CPC分类号： B01L3/502738 , B01L3/50273 , B01L3/502792 , B01L2200/0605 , B01L2200/0647 , B01L2200/16 , B01L2300/0806 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2300/1861 , B01L2400/0409 , B01L2400/0677
摘要： PROBLEM TO BE SOLVED: To provide a centrifugal force based microflow apparatus for dilution and a microflow system comprising it. SOLUTION: This apparatus includes: rotatable disc type platform 10; a mixing chamber 50 arranged on the platform 10; a buffer liquid preservation part which is arranged nearer to the mixing chamber 50 than to the center of the platform 10, is connected with the mixing chamber 50 through a channel, and supplies a buffer liquid of at least constant quantity each time to the mixing chamber 50; and a plurality of dilution chambers 61-67 which are arranged farther from the center of the platform 10 than the mixing chamber 50, each of which is connected to the mixing chamber 50 through a channel extending from a middle outlet corresponding to a fixed water level of the mixing chamber 50, and which sequentially receive the dilution which has been diluted in the mixing chamber 50 at least once. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于稀释的基于离心力的微流装置和包括其的微流系统。解决方案：该装置包括：旋转盘式平台10; 布置在平台10上的混合室50; 配置在比混合室50更靠近平台10的中心的缓冲液保存部通过通道与混合室50连接，并且每次将至少一定量的缓冲液供给混合室 50; 以及多个稀释室61-67，其布置成比混合室50更靠近平台10的中心，每个混合室通过从对应于固定水位的中间出口延伸的通道连接到混合室50 的混合室50，并且其顺序地接收已经在混合室50中稀释的稀释液至少一次。版权所有（C）2008，JPO＆INPIT

6. 发明专利

JP2007275057A Method for concentrating and breaking cell or virus 审中-公开
标题翻译：用于浓缩和破坏细胞或病毒的方法
公开(公告)号：JP2007275057A
公开(公告)日：2007-10-25
申请号：JP2007065329
申请日：2007-03-14
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： CHO YOON-KYOUNG , LEE JEONG-GUN , PARK SHOBEN , LEE YOUNG-SUN , LEE KOEN
IPC分类号： C12N15/09 , C12M1/33 , C12N1/02 , C12N1/06 , C12N7/02
CPC分类号： C12N1/066 , C12M47/06 , C12N13/00 , G01N33/54326
摘要： PROBLEM TO BE SOLVED: To provide a method for concentrating and breaking a cell or a virus.
SOLUTION: The method for concentrating and breaking the cell or the virus comprises a step for pouring beads into a solution containing the cell or the virus and concentrating the cell or the virus on the beads and a step for breaking the cell or the virus by irradiating laser to the beads.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供用于浓缩和破坏细胞或病毒的方法。解决方案：用于浓缩和断裂细胞或病毒的方法包括将珠子倒入含有细胞或病毒的溶液中并将细胞或病毒浓缩在珠上的步骤以及用于破坏细胞或病毒通过向珠子照射激光。版权所有（C）2008，JPO＆INPIT

7. 发明专利

JP2006142294A Microfluidic system comprising microchannel in which a plurality of electromagnets are arranged, and methods of mixing sample and dissolving cell with the microfluidic system 审中-公开
标题翻译：微电子系统包含多个电磁网络的微通道，以及混合样品和溶解电池与微流控系统的方法
公开(公告)号：JP2006142294A
公开(公告)日：2006-06-08
申请号：JP2005332185
申请日：2005-11-16
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： KIM JIN-TAE , OH KWANG-WOOK , CHO YOON-KYOUNG , PAEK SANGHYUN , KIM SOOK-YOUNG , PARK CHIN-SUNG , NAMKOONG KAK
IPC分类号： B01F13/08 , C12M1/00 , G01N35/08 , G01N37/00
CPC分类号： C12N1/066 , B01F13/0059 , B01F13/0809
摘要： PROBLEM TO BE SOLVED: To provide a microfluidic system comprising a microchannel in which a plurality of electromagnets are arranged, and methods of mixing a sample and dissolving a cell with the microfluidic system.
SOLUTION: There is provided a microfluidic system comprising at least an inlet and at least an outlet, the inlet and the outlet being connected through a microchannel 400, wherein two or more electromagnets are arranged in a predetermined direction to a wall surface of the microchannel 400 relative to the proceeding direction of a fluid passing through the microchannel 400.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种微流体系统，其包括其中布置有多个电磁体的微通道，以及混合样品并将细胞溶解于微流体系统的方法。解决方案：提供了一种微流体系统，其至少包括入口和至少一个出口，入口和出口通过微通道400连接，其中两个或多个电磁体沿预定方向布置在微通道400相对于通过微通道400的流体的行进方向。（C）2006年，JPO和NCIPI

8. 发明专利

JP2006084465A Optical system for analyzing multi-channel sample and multi-channel sample analyzer using it 有权
标题翻译：用于分析多通道样品的光学系统和使用其的多通道样品分析仪
公开(公告)号：JP2006084465A
公开(公告)日：2006-03-30
申请号：JP2005256561
申请日：2005-09-05
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： OK GYEONG-SIK , CHO YOON-KYOUNG , KIM JIN-TAE , OH KWANG-WOOK
IPC分类号： G01N21/64
CPC分类号： G01N21/645
摘要： PROBLEM TO BE SOLVED: To provide an optical system for analyzing multi-channel samples which uses a high-speed rotating mirror and an aspherical mirror, and a multi-channel analyzer using the optical system.
SOLUTION: This optical system comprises: a light source unit 10 emitting light traveling along an optical axis; a semi-spheroid aspherical mirror 30 disposed in rotational symmetry about the optical axis; and an inclined mirror 41 reflecting the light exiting the light source unit to the semi-spheroid aspherical mirror, while rotating about the optical axis, wherein an opening is formed in the center of the semi-spheroid aspherical mirror so that the light emitted from the light source unit can enter the inclined mirror through the semi-spheroid aspherical mirror. According to this, a plurality of samples are measured while preventing optical strokes between the samples, and parts to be used are miniaturized.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：解决的问题：提供一种用于分析使用高速旋转镜和非球面镜的多通道样本的光学系统和使用该光学系统的多通道分析仪。解决方案：该光学系统包括：光源单元10，其发射沿着光轴行进的光; 围绕光轴旋转对称设置的半球体非球面镜30; 以及在围绕光轴旋转的同时将离开光源单元的光反射到半球形非球面镜的倾斜镜41，其中在半球体非球面镜的中心形成有开口，使得从光源单元可以通过半球体非球面镜进入倾斜镜。据此，在防止样品之间的光笔冲击的同时测量多个样品，并且使用的部件被小型化。版权所有（C）2006，JPO＆NCIPI

9. 发明专利

JP2008121890A Valve unit, microfluidic device including valve unit and microfluidic substrate 有权
标题翻译：阀门单元，包括阀门单元和微流体基板的微流体装置
公开(公告)号：JP2008121890A
公开(公告)日：2008-05-29
申请号：JP2007284068
申请日：2007-10-31
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： LEE BEOM SEOK , CHO YOON-KYOUNG , LEE JEONG-GUN , PARK SHOBEN
IPC分类号： F16K17/38 , B01J19/00 , F16K13/00 , F16K13/10 , F16K31/66 , G01N35/00 , G01N37/00
CPC分类号： B01L3/502738 , B01L2300/0806 , B01L2300/1861 , B01L2400/0409 , B01L2400/0677 , Y10T137/4643 , Y10T436/2575
摘要： PROBLEM TO BE SOLVED: To provide a valve unit, a microfluidic device including a valve unit and a microfluidic substrate. SOLUTION: The valve unit 40A and the microfluidic device having it, respectively include: a valve substance container 42A containing a valve substance, the valve substance including a phase change material that is solid at ambient temperature and melts by absorbing energy; a valve connection path 44A connecting a channel 35 forming a fluid passage and a valve chamber; and a pair of drain chambers 46, 47 provided on both sides of the valve connection path on the channel, wherein energy is supplied to the valve substance cured in the valve substance container or in the interior of the valve connection path to melt, move and re-cure the valve substance, so that the channel is closed, and energy is supplied to the valve substance closing the channel, thereby discharging the valve substance to the drain chambers to open the channel. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种阀单元，包括阀单元和微流体基板的微流体装置。阀组件40A及具有该阀单元的微流体装置分别包括：阀体物质容器42A，其包含阀体物质，所述阀体物质包括在环境温度下为固体并通过吸收能量而熔融的相变材料; 连接形成流体通道的通道35和阀室的阀连接路径44A; 以及设置在通道上的阀连接路径的两侧的一对排水室46,47，其中能量被供应到在阀体容器中固化的阀体或阀连接路径的内部，以熔化，移动和重新固化阀门物质，使通道关闭，并将能量供给阀关闭通道的阀门物质，从而将阀门物质排放到泄放室以打开通道。版权所有（C）2008，JPO＆INPIT

10. 发明专利

JP2008064753A Fine fluid apparatus for use in protein detection based on centrifugal force and fine fluid system including same 有权
标题翻译：基于离心力和微流体系统的蛋白质检测中使用的精细流体装置
公开(公告)号：JP2008064753A
公开(公告)日：2008-03-21
申请号：JP2007226832
申请日：2007-08-31
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： LEE BEOM SEOK , CHO YOON-KYOUNG , LEE JEONG-GUN , PARK SHOBEN
IPC分类号： G01N35/00 , G01N21/78 , G01N33/53 , G01N37/00
CPC分类号： G01N33/54326 , B01L3/50273 , B01L3/502738 , B01L3/502761 , B01L2200/0647 , B01L2300/0806 , B01L2300/0867 , B01L2300/1861 , B01L2400/0409 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , G01N33/54366 , Y10T436/25375
摘要： PROBLEM TO BE SOLVED: To provide a fine fluid apparatus for use in protein detection based on centrifugal force and a fine fluid system including the fine fluid apparatus. SOLUTION: The fine fluid system includes a fine fluid apparatus for use in target protein detection based on centrifugal force. The fine fluid apparatus includes: a rotor 100; a fine fluid structure 101, disposed in the rotor, which includes a plurality of passages that connect a plurality of chambers to one another and a plurality of valves disposed in the passages so as to control the flow of fluid, the fine fluid structure 101 transporting the fluid with use of centrifugal force caused by rotation of the rotor; beads, disposed in the fine fluid structure, each of whose surfaces has a capture probe having specific affinity for target protein; and a detection probe, disposed in the fine fluid structure, which has specific affinity for the target protein and contains a substance necessary for expression of an optical signal, the fine fluid structure mixing the beads with a biological sample and the detection probe for reaction and washing and separating the beads after the reaction. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于基于离心力的蛋白质检测的精细流体装置和包括精细流体装置的精细流体系统。
解决方案：细流体系统包括用于基于离心力的靶蛋白检测的精细流体装置。精细流体装置包括：转子100; 设置在转子中的精细流体结构101，其包括将多个室彼此连接的多个通道和设置在通道中的多个阀，以便控制流体的流动，精细流体结构101运送使用由转子旋转引起的离心力的流体; 微珠，其处于微细的流体结构中，每个表面具有对靶蛋白具有特异性亲和性的捕获探针; 以及检测探针，其设置在微细流体结构中，其对靶蛋白具有特异性亲和性，并且含有表达光信号所必需的物质，将珠与生物样品混合的细流体结构和用于反应的检测探针，以及反应后洗涤和分离珠粒。版权所有（C）2008，JPO＆INPIT

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