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1. 发明专利

JP2008079604A Primer set, probe set, method and kit each for predicting alcoholysis ability and resistance to overnight drunkenness 审中-公开
标题翻译： PRIMER SET，PROBE SET，方法和试剂盒，用于预测醇溶性和抵抗过敏性感染
公开(公告)号：JP2008079604A
公开(公告)日：2008-04-10
申请号：JP2007213971
申请日：2007-08-20
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： PAEK SANGHYUN , OH JI-YOUNG , KIM SOOK-YOUNG , LEE JUNG-NAM , TEI SHOSEKI
IPC分类号： C12N15/09 , C12M1/00 , C12Q1/68 , G01N33/53 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a primer set, a probe set, a method and a kit each for predicting alcoholysis ability and overnight drunkenness. SOLUTION: The oligonucleotide primer set is provided, being intended for amplifying one or more target sequences selected from the group consisting of acetaldehyde dehydrogenase 2(ALDH2), cytochrome P450 2E1(CYP2E1) and alcohol dehydrogenase 2 (ADH2) genes. The probe set is provided, being specifically hybridizable with one or more target sequences selected from the group consisting of the acetaldehyde dehydrogenase 2(ALDH2), cytochrome P450 2E1(CYP2E1) and alcohol dehydrogenase 2 (ADH2) genes. A microarray is provided, being such as to be immobilized with the probe set. The method for predicting the alcoholysis ability and the overnight drunkenness utilizing the probe set is also provided. Further, the kit for predicting the alcoholysis ability and the overnight drunkenness is provided, involving the primer set and the probe set. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供用于预测醇解能力和过夜醉酒的引物组，探针组，方法和试剂盒。提供了寡核苷酸引物组，旨在扩增选自乙醛脱氢酶2（ALDH2），细胞色素P450 2E1（CYP2E1）和醇脱氢酶2（ADH2）基因的一种或多种靶序列。提供探针组，其与选自乙醛脱氢酶2（ALDH2），细胞色素P450 2E1（CYP2E1）和醇脱氢酶2（ADH2））基因的一种或多种靶序列特异性杂交。提供微阵列，使其与探针组固定。还提供了利用探针组预测醇解能力和过夜醉酒的方法。此外，提供了用于预测醇解能力和过夜醉酒的试剂盒，涉及引物组和探针组。版权所有（C）2008，JPO＆INPIT

2. 发明专利

JP2006174837A Primer set and probe oligonucleotide specific for 10 kinds of bacteria associated with respiratory diseases 有权
标题翻译：与呼吸道疾病相关的10种细菌的PRIMER SET AND PROBE OLIGONUCLEOTIDE SPECIFIC
公开(公告)号：JP2006174837A
公开(公告)日：2006-07-06
申请号：JP2005368285
申请日：2005-12-21
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： OH JI-YOUNG , HUH NAM , PAEK SANGHYUN , JEONG SUNG-YOUNG
IPC分类号： C12N15/09 , C12M1/00 , C12Q1/68
CPC分类号： C12Q1/689
摘要： PROBLEM TO BE SOLVED: To provide a primer set capable of specifically amplifying target sequences of ten kinds of bacteria associated with respiratory diseases and a probe oligonucleotide specific for each target sequence of the bacteria and not causing a cross reaction with other nucleic acids. SOLUTION: Disclosed is a target sequence-amplifying primer set comprising an oligonucleotide having a fragment comprising continuous ten or more bases of a specific sequence and length of 10bp to 100bp, and an oligonucleotide having a fragment comprising continuous ten or more bases of another specific sequence and length of 10bp to 100bp, and specific for Bordetella pertussis, Chlamydophila pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae, Legionella pneumoniae, Moraxella catarrhalis, Mycoplasma pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae. Also disclosed is a probe oligonucleotide specific for each of the ten kinds of the bacteria. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供能够特异性扩增与呼吸系统疾病相关的十种细菌的靶序列的引物组和对细菌的每个靶序列特异的探针寡核苷酸，并且不与其它核酸发生交叉反应。解决方案：公开了一种靶序列扩增引物组，其包含具有包含连续十个或更多个特定序列和长度为10bp至100bp的碱基的片段的寡核苷酸，以及具有包含连续十个或更多个碱基的片段的寡核苷酸另外具体的序列长度为10bp至100bp，特异性为百日咳杆菌，肺炎衣原体，流感嗜血杆菌，肺炎克雷伯杆菌，肺炎军团菌，卡他莫拉菌，肺炎支原体，铜绿假单胞菌，金黄色葡萄球菌和肺炎链球菌。还公开了对十种细菌中的每一种特异的探针寡核苷酸。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2007171180A Substrate for microarray and manufacturing method therefor 有权
标题翻译：微波炉及其制造方法的基板
公开(公告)号：JP2007171180A
公开(公告)日：2007-07-05
申请号：JP2006339085
申请日：2006-12-15
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： PARK JONG-MYEON , PAEK SANGHYUN
IPC分类号： G01N33/543 , G01N33/53 , G01N37/00
CPC分类号： G01N33/54353 , B01J19/0046 , B01J2219/00527 , B01J2219/00529 , B01J2219/00576 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00677 , G01N33/54393
摘要： PROBLEM TO BE SOLVED: To provide a substrate for microarray, and to provide its manufacturing method.
SOLUTION: The substrate for microarray is a solid support, which has surface of poly-anhydride polymer, coated with at least either one of ethylene glycol compound with a functional group introduced or polyethylene glycol compound. By using this substrate for microarray, immobilization efficiency of probe is improved, as well as preventing nonspecific molecular bond between target biomolecule and protein. Thus, unrefined PCR (Polymerization Chain Reaction) sample can be applied directly to the substrate without tail end process, after the probe has been fixed on the substrate, to achieve simplification of process. Thus chips can be produced at a lower cost, allowing analysis of biomolecules.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供用于微阵列的基板，并提供其制造方法。解决方案：用于微阵列的基质是固体支持物，其具有多酸酐聚合物的表面，其涂覆有引入的官能团的乙二醇化合物或聚乙二醇化合物中的至少一种。通过使用这种底物进行微阵列，提高了探针的固定效率，同时防止靶生物分子与蛋白质之间的非特异性分子键。因此，在将探针固定在基材上之后，未精制PCR（聚合反应链）反应样品可以直接施加到基材上，而无需尾端处理，以实现工艺的简化。因此，可以以更低的成本生产芯片，从而允许分析生物分子。版权所有（C）2007，JPO＆INPIT

4. 发明专利

JP2005172819A Polynucleotide array and method for detecting target polynucleotide using the same 有权
标题翻译：多核苷酸阵列及其检测目标多核苷酸的方法
公开(公告)号：JP2005172819A
公开(公告)日：2005-06-30
申请号：JP2004348670
申请日：2004-12-01
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： PAEK SANGHYUN
IPC分类号： G01N33/53 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N33/543 , G01N37/00
CPC分类号： C12Q1/6837 , C12Q2527/107 , C12Q2527/125
摘要： PROBLEM TO BE SOLVED: To provide a polynucleotide array, containing two or more probe polynucleotide groups immobilized on a substrate by using its Tm (melting temperature), and to provide a method of detecting target polynucleotide, using the polynucleotide array. SOLUTION: The polynucleotide array includes two or more spot groups, in each of which probe polynucleotide belonging to the extent where the Tm for the target polynucleotide is set, is immobilized. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：待解决的问题：使用多核苷酸阵列提供含有通过使用其Tm（熔解温度）固定在底物上的两个或更多个探针多核苷酸组的多核苷酸阵列，并提供检测靶多核苷酸的方法。解决方案：多核苷酸阵列包括两个或更多个点组，其中每个探针多核苷酸属于设定靶多核苷酸的Tm的程度。版权所有（C）2005，JPO＆NCIPI

5. 发明专利

JP2007275067A Method for hybridization of nucleic acid and method for amplification of target nucleic acid 审中-公开
标题翻译：核酸混合方法及放射性核酸的方法
公开(公告)号：JP2007275067A
公开(公告)日：2007-10-25
申请号：JP2007102030
申请日：2007-04-09
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： LEE JUNG-NAM , PAEK SANGHYUN
IPC分类号： C12N15/09 , C12Q1/68
CPC分类号： C12Q1/6832 , C12Q1/6848 , C12Q2527/125
摘要： PROBLEM TO BE SOLVED: To provide a means for increasing the specificity of nucleic acid hybridization. SOLUTION: The method for the hybridization of nucleic acid contains a step to perform the hybridization of a nucleic acid in a solution containing one or more amphoteric ion compounds having amino group, sulfonic acid group and 3-30C substituted or unsubstituted cycloalkyl group. The amphoteric ion compound is one or more compounds selected from 3-(cyclohexylamino)-1-propanesulfonic acid (CAPS), 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid (CHAPS), 3-(cyclohexylamino)-2-hydroxy-1-propanesulfonic acid (CAPSO) and 2-(cyclohexylamino)ethanesulfonic acid (CHES). COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：待解决的问题：提供增加核酸杂交特异性的方法。解决方案：核酸杂交的方法包括在含有一个或多个具有氨基，磺酸基和3-30C取代或未取代的环烷基的两性离子化合物的溶液中进行核酸杂交的步骤。两性离子化合物是一种或多种选自3-（环己基氨基）-1-丙磺酸（CAPS），3- [（3-胆酰胺丙基）二甲基铵] -1-丙磺酸（CHAPS），3-（环己基氨基） - 2-羟基-1-丙磺酸（CAPSO）和2-（环己基氨基）乙磺酸（CHES）。版权所有（C）2008，JPO＆INPIT

6. 发明专利

JP2006142294A Microfluidic system comprising microchannel in which a plurality of electromagnets are arranged, and methods of mixing sample and dissolving cell with the microfluidic system 审中-公开
标题翻译：微电子系统包含多个电磁网络的微通道，以及混合样品和溶解电池与微流控系统的方法
公开(公告)号：JP2006142294A
公开(公告)日：2006-06-08
申请号：JP2005332185
申请日：2005-11-16
申请人： Samsung Electronics Co Ltd , 三星電子株式会社Samsung Electronics Co.,Ltd.
发明人： KIM JIN-TAE , OH KWANG-WOOK , CHO YOON-KYOUNG , PAEK SANGHYUN , KIM SOOK-YOUNG , PARK CHIN-SUNG , NAMKOONG KAK
IPC分类号： B01F13/08 , C12M1/00 , G01N35/08 , G01N37/00
CPC分类号： C12N1/066 , B01F13/0059 , B01F13/0809
摘要： PROBLEM TO BE SOLVED: To provide a microfluidic system comprising a microchannel in which a plurality of electromagnets are arranged, and methods of mixing a sample and dissolving a cell with the microfluidic system.
SOLUTION: There is provided a microfluidic system comprising at least an inlet and at least an outlet, the inlet and the outlet being connected through a microchannel 400, wherein two or more electromagnets are arranged in a predetermined direction to a wall surface of the microchannel 400 relative to the proceeding direction of a fluid passing through the microchannel 400.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种微流体系统，其包括其中布置有多个电磁体的微通道，以及混合样品并将细胞溶解于微流体系统的方法。解决方案：提供了一种微流体系统，其至少包括入口和至少一个出口，入口和出口通过微通道400连接，其中两个或多个电磁体沿预定方向布置在微通道400相对于通过微通道400的流体的行进方向。（C）2006年，JPO和NCIPI

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