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    • 1. 发明专利
    • Preparation of oligosaccharide of sialic acid bond
    • 磷酸二氢钠的制备
    • JPS59184197A
    • 1984-10-19
    • JP5769983
    • 1983-04-01
    • Snow Brand Milk Prod Co Ltd
    • IDEIE SAKANORIAMAYA MIEKONOJIRI KAORUIGARASHI SEIICHIROU
    • C07H13/06A23C7/00C07H1/08
    • PURPOSE: To obtain the titled compound important th respect to physiological activity and nutritive physiology industrially advantageously, by desalting a filtrate of ultrafiltration of a milky raw material substance containing an oligosaccharide of sialic acid bond by electrodialysis, treating it with an anion exchange resin, adjusting it to a proper pH, desalting it again by electrodialysis.
      CONSTITUTION: A filtrate of ultrafiltration of milky raw material substance or molasses prepared in the process of lactose, containing an oligosaccharide of sialic acid bond, is desalted by electrodialysis, passed through a column packed with an anion exchange resin, so that the oligosaccharide of sialic acid is adsorbed on the resin. Water is then passed through the column to remove neutral saccharide. An eluting solution such as hydrochloric acid, etc. is passed through the column to elute the oligosaccharide. The eluate is adjusted to a pH approximately neutrality, and desalted agai by electrodialysis to give the desired oligosaccharide.
      COPYRIGHT: (C)1984,JPO&Japio
    • 目的:为了获得有利于生理活性和营养生理学重要性的标题化合物,通过电渗析对含唾液酸键寡糖的乳状原料物质进行超滤脱盐,用阴离子交换树脂处理,调节 它达到适当的pH值,再次通过电渗析脱盐。 构成:在含有唾液酸键的寡糖的乳糖过程中制备的乳糖原料或糖蜜的超滤滤液通过电渗析脱盐,通过填充有阴离子交换树脂的柱,使得唾液酸的寡糖 酸被吸附在树脂上。 然后将水通过柱以除去中性糖。 将洗脱溶液如盐酸等通过柱洗脱寡糖。 将洗脱液调节至pH近似中性,并通过电渗析脱盐,得到所需的寡糖。