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1. 发明专利

JP2006306465A External bag, alkaline chemical liquid filled container storing member using external bag and storage method for alkaline chemical liquid filled container 审中-公开
标题翻译：外包装袋，碱性化学液体填充容器储存器，使用外包装袋和碱性化学液体填充容器的储存方法
公开(公告)号：JP2006306465A
公开(公告)日：2006-11-09
申请号：JP2005132623
申请日：2005-04-28
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： MANABE HIROKI , OKAMOTO HIDESHI , KAWAKAMI KEIICHI
IPC分类号： B65D81/24 , A61J1/10 , B32B27/00 , B65D30/02 , B65D65/40 , B65D77/04 , B65D85/84
摘要： PROBLEM TO BE SOLVED: To provide an external bag restricting occurrence of clouding in alkaline chemical liquid even if the chemical liquid container filled with the alkaline chemical liquid and sealed is stored in the external bag having carbon dioxide gas barrier properties, sealed and stored, an alkaline chemical liquid filled container storing member using the external bag and a method for storing the alkaline chemical liquid filled container. SOLUTION: The alkaline chemical liquid filled container comprised of a plastic container and an alkaline chemical liquid filled and sealed in the plastic container is stored and sealed in an external bag comprised of a multi-layer plastic film 1 having a carbon dioxide gas barrier layer 3 in which a more inner side (i) layer than the carbon dioxide gas barrier layer 3 in the multi-layer plastic film 1 is a layer 2 composed of plastic substantially not containing higher fatty acid and its salts. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了提供限制碱性化学液体发生混浊的外袋，即使填充有碱性化学液体的药液容器被密封储存在具有二氧化碳气体阻隔性的外袋中，密封和储存，使用外部袋的碱性化学液体填充容器存储构件和用于储存碱性化学液体填充容器的方法。解决方案：将由塑料容器和填充并密封在塑料容器中的碱性化学液体组成的碱性化学液体填充容器储存并密封在由具有二氧化碳气体的多层塑料膜1组成的外部袋中多层塑料薄膜1中比二氧化碳气体阻隔层3多的内侧（i）层是由基本上不含高级脂肪酸的塑料及其盐构成的层2的阻挡层3。版权所有（C）2007，JPO＆INPIT

2. 发明专利

JP2006122128A Container of nutrient for fistula supply 审中-公开
标题翻译：营养供应集装箱
公开(公告)号：JP2006122128A
公开(公告)日：2006-05-18
申请号：JP2004311310
申请日：2004-10-26
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： MIZUKAI KAZUYA , MIYASHITA KEIICHI , KAWAKAMI KEIICHI
IPC分类号： A61J1/00 , A61J1/05 , A61J15/00 , B65D30/02 , B65D33/38 , B65D35/02
摘要： PROBLEM TO BE SOLVED: To provide a container of nutrients for fistula supply with which the appropriate amount of the nutrient is easily supplied by one administration. SOLUTION: The container 10 for putting in the nutrient to be supplied through a fistula to the stomach or intestines is provided with a bag 11 having a housing chamber 17 where the nutrient is housed and a spout 12 attached to the bag 11 and communicated with the housing chamber 17. The bag 11 is deformed in accordance with external force and thus the nutrient housed in the housing chamber 17 is discharged from the spout 12. The bag 11 is formed of such a material that the deformed bag is not naturally restored to a form before being deformed even when the external force is removed. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供用于瘘供应的营养物质的容器，通过该容器容易地由一个给药提供适量的营养物质。解决方案：用于将通过瘘管供应的营养物质放入胃或肠的容器10设置有具有容纳营养物的容纳室17的袋11和附接到袋11的喷口12，与容纳室17连通。袋11根据外力而变形，因此容纳在容纳室17中的营养物从喷口12排出。袋11由这样的材料形成，即变形袋不是天然的即使外力被去除，也可以在变形之前恢复成形状。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2005087570A Medicament container, package material, and medicament package 有权
标题翻译：药物容器，包装材料和药物包装
公开(公告)号：JP2005087570A
公开(公告)日：2005-04-07
申请号：JP2003326850
申请日：2003-09-18
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： MITSUMOTO YASUHIRO , ARITA SHIGEAKI , KAWAKAMI KEIICHI
IPC分类号： B65D81/30 , A61J1/00 , A61K9/08
摘要： PROBLEM TO BE SOLVED: To provide a medicament container, a package material and a medicament package permitting facilitating the product inspection while excellently keeping the stability of vitamin B1. SOLUTION: The medicament package 1 comprises the medicament container 3 for storing a medicament including vitamin B1, having a container body 7 made of a material whose light transmittance is not more than 5% when the wavelength λ is in the range of 200 COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供药物容器，包装材料和药物包装，其允许促进产品检查，同时优良地保持维生素B1的稳定性。解决方案：药物包装1包括用于储存包含维生素B1的药物的药物容器3，当维生素B1的波长λ在200的范围内时，其具有由透光率不大于5％的材料制成的容器主体7 <λ≤305nm，当波长λ为450nm时为至少50％，以及用于储存药物容器3的透明或半透明的包装材料5.版权所有（C）2005，JPO＆NCIPI

4. 发明专利

JP2004337318A Medical double-chamber container and manufacturing method therefor 审中-公开
公开(公告)号：JP2004337318A
公开(公告)日：2004-12-02
申请号：JP2003136546
申请日：2003-05-14
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： KAWAKAMI KEIICHI , OKAMOTO HIDESHI
IPC分类号： B65D81/32 , A61J1/05 , A61J1/10 , B65D30/22 , B65D77/08
摘要： PROBLEM TO BE SOLVED: To provide a medical double-chamber container and a manufacturing method therefor, which enable manufacture using relatively small-scale equipment even in the case of the container for a special drug such as a steroid drug, a biological preparation or an anticancer drug, and which enable a production of many types. SOLUTION: This medical double-chamber container is equipped with: a small container 11 wherein the steroid drug, the biological preparation or the anticancer drug is housed and which can be unsealed by an external force; a flexible container body 5 which has a storage chamber 9 for housing the small container 11 and wherein a solution or a diluent is housed in the storage chamber 9; and a drug ejecting part 7 which is attached to the container body 5 and which communicates with the storage chamber 9. COPYRIGHT: (C)2005,JPO&NCIPI

5. 发明专利

JP2004121751A Double-chamber container and heating seal metal mold used for manufacture of the same 有权
公开(公告)号：JP2004121751A
公开(公告)日：2004-04-22
申请号：JP2002293964
申请日：2002-10-07
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： KUME KOICHI , NAGAO KATSUMI , KAWAKAMI KEIICHI
IPC分类号： B65D81/32 , A61J1/05 , B65D77/08
摘要： PROBLEM TO BE SOLVED: To provide a double-chamber container having a partition wall that is not torn open by a load like a drop impact momentarily applied to the chambers, but by a load like manual pressure continuously applied to them, and a heating seal metal mold used for manufacturing such a partition wall with the above characteristics. SOLUTION: In a flexible double-chamber container 11 having a plurality of chambers 13a and 13b separated by an easy-to-peel seal partition 12 and a strong seal circumference 14, at least two different degrees of peel strengths are set up for the partition wall 12, and a hard-to-peel seal partition wall 12a with higher peel strength continuously is stretched from one circumference area 14 to the other circumference area 14 adjacently to the partition wall 12. COPYRIGHT: (C)2004,JPO

6. 发明专利

JP2004106881A Flexible object housing body 审中-公开
公开(公告)号：JP2004106881A
公开(公告)日：2004-04-08
申请号：JP2002271507
申请日：2002-09-18
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： INOUE FUJIO , KAWAKAMI KEIICHI , OKAMOTO HIDESHI
IPC分类号： B65D83/00 , A61J1/00 , A61J1/05 , B65D30/22 , B65D77/08
摘要： PROBLEM TO BE SOLVED: To surely extrude a content in such a manner that a state wherein the flexible content remaining a container may become totally empty or almost empty. SOLUTION: For this flexible object housing body, a flexible medicament and a gas are housed in a container main body 1. The container main body 1 is equipped with a first housing chamber 3 in which the medicament is housed, a second housing chamber 5 in which the gas is housed, a partitioning part 7 which normally partitions the first and second housing chambers 3 and 5, and unsealing the second housing chamber at the time of use by increasing the internal pressure of the second housing chamber, and a discharging part which is provided on the first housing chamber 3, and from which the medicament is discharged. The gas which is housed in the second housing chamber 5 is enclosed by a pressure being the same as or higher than the atmosphere. COPYRIGHT: (C)2004,JPO

7. 发明专利

JP2003063965A Cilostazol aqueous composition for injection 审中-公开
标题翻译： CILOSTAZOL注射用水性组合物
公开(公告)号：JP2003063965A
公开(公告)日：2003-03-05
申请号：JP2002127065
申请日：2002-04-26
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： INOUE FUJIO , KAWAKAMI KEIICHI , NAGAYASU SHINYA , OKAMOTO HIDESHI
IPC分类号： A61K9/08 , A61K9/00 , A61K31/4709 , A61K47/32 , A61K47/36 , A61K47/40 , A61P1/04 , A61P7/02 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/06 , A61P29/00 , A61P43/00
CPC分类号： A61K47/40 , A61K9/0019 , A61K31/4709
摘要： PROBLEM TO BE SOLVED: To provide a cilostazol- or its salt-containing aqueous composition for injection which is improved in stability during its storage by increasing the solubility in water of cilostazol or its pharmaceutically acceptable salt.
SOLUTION: The cilostazol aqueous composition for injection characteristically contains cilostazol or its pharmaceutically acceptable salt as an active ingredient and a cyclodextrin.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供一种西洛他唑或其含盐的注射用水性组合物，其通过增加西洛他唑或其药学上可接受的盐在水中的溶解度而在其储存期间的稳定性得到改善。解决方案：用于注射的西洛他唑含水组合物特征性地含有西洛他唑或其药学上可接受的盐作为活性成分和环糊精。

8. 发明专利

JP2008104868A Plastic ampule 有权
标题翻译：塑料电池
公开(公告)号：JP2008104868A
公开(公告)日：2008-05-08
申请号：JP2007247703
申请日：2007-09-25
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： MANABE HIROKI , INOUE TADAAKI , OKAMOTO HIDESHI , KAWAKAMI KEIICHI
IPC分类号： A61J1/06 , B65D1/00 , B65D1/02 , B65D17/40
摘要： PROBLEM TO BE SOLVED: To provide a plastic ampule, restricting volatilization/scattering of liquid medicine contained in the plastic ampule and elution of compounding agents of plastics into the liquid medicine, and restricting generation of whiskers, and deformation/breakage of an opening part when opening the plastic ampule. SOLUTION: The plastic ampule 10 is provided with a liquid medicine containing part 11, a liquid medicine discharge cylinder part 12 communicated with the medicine containing part 11, and extended toward one side, and a top part 13 to close one end part of the medicine discharge cylinder part 12. On the medicine discharge cylinder part 12, a fragile part 14 is thinly formed along the circumference. The medicine containing part 11, the medicine discharge cylinder part 12, and the top part 13 are formed of multi-layer plastic including an intermediate layer including a cyclic olefin-based (co-)polymer of a glass transition temperature of 60-80°C, an inner layer laminated on the inside of the intermediate layer, an outer layer laminated on the outer side of the intermediate layer, and adhesive layers respectively disposed between the intermediate layer and the inner layer, and between the outer layer and the intermediate layer. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种塑料安瓿，限制塑料安瓿中所含的液体药物的挥发/散射，并将塑料的配料剂洗脱到液体药物中，并限制晶须的产生和变形/破裂打开塑料安瓿时的开口部分。解决方案：塑料安瓿10设置有药液容纳部11，与药剂容纳部11连通并朝向一侧延伸的药液排出筒部12，顶部13封闭一端部在药液排出筒部12上，沿圆周方向形成有易碎部14。含药部11，药液排出筒部12以及顶部13由多层塑料形成，该多层塑料包括中间层，该中间层包含玻璃化转变温度为60〜80℃的环状烯烃系（共）聚合物 C，层叠在中间层的内侧的内层，层叠在中间层的外侧的外层和分别设置在中间层和内层之间以及外层与中间层之间的粘合层。版权所有（C）2008，JPO＆INPIT

9. 发明专利

JP2006187429A Manufacturing method of medical double-packaged pharmaceutical and medical double packaged pharmaceutical 有权
标题翻译：医药双包装药物和医药双包装药物的制造方法
公开(公告)号：JP2006187429A
公开(公告)日：2006-07-20
申请号：JP2005000994
申请日：2005-01-05
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： TANI HARUHITO , SUMIYOSHI NOBUAKI , ARITA SHIGEAKI , KAWAKAMI KEIICHI , NAGAO KATSUMI
IPC分类号： A61J1/00 , A61J1/10
摘要： PROBLEM TO BE SOLVED: To provide a medical double-packaged pharmaceutical having superior quality stability, a preservation safety and handling property. SOLUTION: This manufacturing method of a medical double-packaged pharmaceutical includes a process for tightly sealing a pharmaceutical storage container 1, which is made of oxygen easily-permeable plastic and is provided with a small container 2 sealed with easily-oxidizing pharmaceutical 22 in a storage chamber 3 and the storage chamber 3 filled with liquid, along with deoxidizer 6 in an oxygen-barrier external bag 5; and a process for retaining the double-packaged body with the small container non-exposed to a headspace 7 in the storage chamber till the oxygen is substantially non-existed in the headspace in the storage chamber. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供具有优异的质量稳定性，保存安全性和处理性的医用双重包装药物。解决方案：医药性双重包装药物的制造方法包括密封由易透氧塑料制成的药物储藏容器1的方法，并且设置有用容易氧化的药物密封的小容器2 22和储存室3中，以及在氧隔离外袋5中与脱氧剂6一起填充液体; 以及将储存室中没有暴露于顶部空间7的小容器保持双重包装体的方法，直到氧气基本上不存在于储存室的顶部空间中。版权所有（C）2006，JPO＆NCIPI

10. 发明专利

JP2006124286A Multiple infusion preparation 审中-公开
标题翻译：多种输注制剂
公开(公告)号：JP2006124286A
公开(公告)日：2006-05-18
申请号：JP2004311375
申请日：2004-10-26
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： SUMIYOSHI NOBUAKI , TANI HARUHITO , IZUI SEIJI , ARITA SHIGEAKI , KAWAKAMI KEIICHI
IPC分类号： A61K31/047 , A61J1/05 , A61K31/07 , A61K31/122 , A61K31/195 , A61K31/355 , A61K31/409 , A61K31/51 , A61K31/59 , A61K33/24 , A61P3/02 , B65D30/22 , B65D81/32
摘要： PROBLEM TO BE SOLVED: To provide a multiple infusion preparation excellent in stability of vitamin B 1 . SOLUTION: The multiple infusion preparation comprises (A) a reducing sugar solution and (B) an amino acid solution separately stored in each chamber of a container having two chambers partitioned by a communication-free partition wall and (C) a vitamin B 1 solution stored in a small container which is capable of communicating with either one of the two chambers. COPYRIGHT: (C)2006,JPO&NCIPI

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