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1. 发明专利

JP2013088164A Automatic analyzer 审中-公开
标题翻译：自动分析仪
公开(公告)号：JP2013088164A
公开(公告)日：2013-05-13
申请号：JP2011226617
申请日：2011-10-14
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： HARADA YUJI , YAMASHITA YOSHIHIRO , SAKAZUME TAKU
IPC分类号： G01N35/02
摘要： PROBLEM TO BE SOLVED: To provide an automatic analyzer in which a capture magnetic field strength in B/F separation can be changed in accordance with the kind of a substance to be measured and a high-precision stable measurement result can be obtained regardless of the kind of the substance to be measured.SOLUTION: A B/F separation mechanism 10 comprises a reaction vessel 11 in which a liquid sample containing magnetic particles is accommodated, a reaction vessel holder 12 which holds the reaction vessel 11, a reaction vessel holder temperature adjusting mechanism 13 which adjusts a temperature of the reaction vessel holder 12, a reaction vessel stirring mechanism which stirs the liquid sample in the reaction vessel, and a magnetic field generating mechanism 15 which is disposed along the outer periphery of the reaction vessel. The magnetic field generating mechanism 15 includes a plurality of magnetic field generation members 15a which are disposed symmetrically to the reaction vessel 11 and a magnetic field strength adjusting mechanism which adjusts the strength of a magnetic field which is generated within the reaction vessel 11 by the magnetic field generation members 15a.
摘要翻译：要解决的问题：提供一种自动分析器，其中可以根据待测物质的种类改变B / F分离中的捕获磁场强度并且可以获得高精度稳定的测量结果不管要测量的物质的种类。解决方案：AB / F分离机构10包括其中容纳含有磁性颗粒的液体样品的反应容器11，保持反应容器11的反应容器保持器12，反应容器保持器温度调节机构13，其调节反应容器保持器12的温度，搅拌反应容器中的液体样品的反应容器搅拌机构，以及沿着反应容器的外周配置的磁场产生机构15。磁场产生机构15包括多个对应于反应容器11设置的磁场产生部件15a和磁场强度调节机构，该磁场强度调节机构通过磁场调节在反应容器11内产生的磁场的强度场产生部件15a。版权所有（C）2013，JPO＆INPIT

2. 发明专利

JP2013246090A Autoanalyzer and pretreatment equipment 有权
标题翻译：自动加油机和预处理设备
公开(公告)号：JP2013246090A
公开(公告)日：2013-12-09
申请号：JP2012121014
申请日：2012-05-28
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： HARADA YUJI , SAKAZUME TAKU , YAMASHITA YOSHIHIRO
IPC分类号： G01N35/00 , G01N35/02
摘要： PROBLEM TO BE SOLVED: To provide an autoanalyzer which a reaction vessel agitation part which can be held at predetermined temperature without spoiling measurement accuracy while having a simple structure.SOLUTION: Temperature of a reaction vessel 211 is controlled via a bearing 224 and a rotation part 232 which accommodates the reaction vessel 211 to rotate by supporting the rotation part 232 via the bearing 224 and performing temperature control of a fixation part of the bearing 224 by a temperature control part 223. Thus, the temperature of the temperature control part 223 can be controlled by arranging a temperature sensor 225 at the temperature control part 223 which is the fixation part, and it becomes possible to hold the temperature control part 223 at predetermined temperature without spoiling measurement accuracy while having a simple structure.
摘要翻译：要解决的问题：提供一种自动分析仪，其可以保持在预定温度的反应容器搅拌部分，而不会损坏测量精度，同时具有简单的结构。解决方案：反应容器211的温度通过轴承224和旋转部分 232，其通过支撑轴承224支撑旋转部232而容纳反应容器211旋转，并且通过温度控制部223对轴承224的固定部进行温度控制。因此，温度控制部223的温度可以通过在作为固定部的温度控制部223设置温度传感器225来控制，并且可以将温度控制部223保持在预定温度，而不会损坏测量精度，同时具有简单的结构。

3. 发明专利

JP2010276392A Flow channel switching valve, flow injection device, liquid chromatography device, supercritical chromatography device, and analyzing system 有权
标题翻译：流通道切换阀，流动注射装置，液体色谱装置，超临界色谱装置和分析系统
公开(公告)号：JP2010276392A
公开(公告)日：2010-12-09
申请号：JP2009127154
申请日：2009-05-27
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： DEGUCHI KISABURO , HARADA YUJI
IPC分类号： G01N30/26
摘要： PROBLEM TO BE SOLVED: To provide a flow channel switching valve reducing the cross contamination (contamination) of a liquid.
SOLUTION: In the flow channel switching valve equipped with: a stator 1 having a plurality of through-holes; a rotor seal 2 rotated while brought into contact with the stator 1 to switch flow channels; and a drive part 3 for rotating the rotor seal 2, the flow channels 4-6 connecting the different through-holes are provided in the rotor seal 2. By this constitution, when the flow channels 4-6 are switched over by rotating the rotor seal 2, the amount of the fluid dragged from the surface of the rotor seal 2 is reduced.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种减少液体的交叉污染（污染）的流路切换阀。解决方案：在具有多个通孔的定子1的流道切换阀中，转子密封件2在与定子1接触的同时旋转以切换流动通道; 以及用于旋转转子密封件2的驱动部件3，在转子密封件2中设置有连接不同通孔的流路4-6。通过这种结构，通过旋转转子密封件2，从转子密封件2的表面拖出的流体的量减少。版权所有（C）2011，JPO＆INPIT

4. 发明专利

JP2008076243A Chromatograph device and analysis method 有权
标题翻译：色谱装置和分析方法
公开(公告)号：JP2008076243A
公开(公告)日：2008-04-03
申请号：JP2006256113
申请日：2006-09-21
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： HARADA YUJI , KUBO SHINTARO , YOKOKURA TAKEFUMI , MIURA JUNKICHI , ITO MASATO
IPC分类号： G01N30/86 , G01N27/62 , G01N30/72
摘要： PROBLEM TO BE SOLVED: To significantly shorten analysis time without reducing analysis accuracy.
SOLUTION: This chromatograph device including liquid chromatograph comprises a sample injecting section for injecting analysis samples, a separation column for separating the analysis samples injected by the sample injecting section component by component, a detector for detecting the component of the analysis samples separated by the separation column, an input section for inputting the number of the analysis samples, a control section for controlling each unit such as the sample injecting section, separation column, detector, or input section so as to analyze the number of the analysis samples specified by the input section, and a recording section for recording chromatogram obtained by analysis. The chromatograph device comprises a storing means for storing the detection time range from the detection start of the component to the completion, a processing means for calculating the injecting interval of the plurality of analysis samples into the sample injecting section based on the detection time range stored in the storing means, and a controlling means for controlling each unit so as to analyze the plurality of analysis samples applying the injecting interval.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：大大缩短分析时间，而不会降低分析精度。该色谱装置包括液相色谱仪，包括用于注入分析样品的样品注射部分，用于分离由样品注入部件分注的分析样品的分离柱，用于检测分离样品分离的组分的检测器通过分离列，输入分析样本的数量的输入部分，用于控制诸如样品注入部分，分离柱，检测器或输入部分的每个单元的控制部分，以分析指定的分析样品的数量通过输入部分和用于记录通过分析获得的色谱图的记录部分。色谱装置包括存储装置，用于存储从部件的检测开始到完成的检测时间范围;处理装置，用于根据存储的检测时间范围计算多个分析样本的注入间隔到样本注入部分在存储装置中，以及控制装置，用于控制每个单元，以分析施加注入间隔的多个分析样本。版权所有（C）2008，JPO＆INPIT

5. 发明专利

JP2007198898A Chromatograph system by precolumn derivation 审中-公开
标题翻译：色谱系统由PRECOLUMN DORIVATION
公开(公告)号：JP2007198898A
公开(公告)日：2007-08-09
申请号：JP2006017598
申请日：2006-01-26
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： HARADA YUJI , KUBO SHINTARO , YOKOKURA TAKEFUMI , MIURA JUNKICHI , ITO MASATO
IPC分类号： G01N30/06 , G01N27/62 , G01N30/04 , G01N30/72 , G01N30/74 , G01N30/78 , G01N30/86 , G01N30/88
摘要： PROBLEM TO BE SOLVED: To realize a chromatograph system for automatically judging the excess and deficiency of a reaction reagent and automatically correcting the amount of the reaction reagent and the amount of an analyzing sample when the reaction reagent is in excess and deficiency.
SOLUTION: The normal range of the peak area value originating from the reaction reagent is set to 800-8,000 and, when an analyzing value exceeding this range is obtained, a sample can be judged to be abnormal. When the analyzing value originating from the reaction reagent is ≤800, the reaction reagent with a concentration of 10 times is used to perform re-analysis. When the analyzing value originating from the reaction reagent dose not exceed 800 even if re-analysis is performed using the reaction reagent with the concentration of 10 times, the reaction reagent with a concentration of 100 times is used to perform re-analysis. When the analyzing value of ≥8,000, the reaction reagent with a concentration of 1/10 times is used to perform re-analysis and, when the analyzing value originating from the reaction reagent does not exceed 8,000, the reaction reagent with a concentration of 1/100 times is used to perform re-analysis.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：实现用于自动判断反应试剂的过量和不足的色谱系统，并且当反应试剂过量和不足时，自动校正反应试剂的量和分析样品的量。解决方案：来自反应试剂的峰面积值的正常范围设定为800〜8000，当得到超过该范围的分析值时，判定为异常。当来自反应试剂的分析值≤800时，使用浓度为10倍的反应试剂进行再分析。即使使用浓度为10倍的反应试剂进行再分析，即使来自反应试剂的分析值不超过800，则使用浓度为100倍的反应试剂进行再分析。当分析值≥8,000时，使用浓度为1/10倍的反应试剂进行重新分析，当来自反应试剂的分析值不超过8000时，浓度为1的反应试剂 / 100次用于执行重新分析。版权所有（C）2007，JPO＆INPIT

6. 发明专利

JP2014106213A Liquid chromatograph auto-sampler 审中-公开
标题翻译：液相色谱自动采样器
公开(公告)号：JP2014106213A
公开(公告)日：2014-06-09
申请号：JP2012261843
申请日：2012-11-30
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： HARADA YUJI , OTSUBO AYANO , ITO MASATO
IPC分类号： G01N30/16 , G01N30/20 , G01N30/26
摘要： PROBLEM TO BE SOLVED: To provide a method for providing a weighing bulb separate from a passage switch valve and weighing a sample in a passage provided in a seal to accurately inject the minute quantity of the sample.SOLUTION: A liquid sample introduction device for a liquid chromatograph comprises: a weighing bulb having a plurality of passages capable of storing the predetermined quantity of sample; a liquid sample introduction part for weighing and sucking the sample to introduce the sample into the passages provided in the weighing bulb; and a passage switch valve for switching the passages so as to introduce the sample introduced into the passages provided in the weighing bulb into a mobile phase passage.
摘要翻译：要解决的问题：提供一种用于提供与通道切换阀分开的称重灯泡并在设置在密封件中的通道中称量样品以精确地注入微量样品的方法。解决方案：一种液体样品引入装置，液相色谱仪包括：具有能够存储预定量样品的多个通道的称重灯泡; 用于称量和吸取样品以将样品引入设置在称重灯泡中的通道中的液体样品引入部分; 以及通道切换阀，用于切换通道，以将引入到设置在称重灯泡中的通道的样品引入流动相通道。

7. 发明专利

JP2013238420A Sample analysis apparatus and sample analysis method 审中-公开
标题翻译：样品分析装置和样品分析方法
公开(公告)号：JP2013238420A
公开(公告)日：2013-11-28
申请号：JP2012109668
申请日：2012-05-11
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： OGI OSAMU , HARADA YUJI , SAKAZUME TAKU , SHIMADA MASAFUMI
IPC分类号： G01N21/64 , G01N35/08
摘要： PROBLEM TO BE SOLVED: To provide a sample analysis apparatus and a sample analysis method which are capable of analysis excellent in sensitivity and repeatability by using a small amount of magnetic particles.SOLUTION: A flat substrate is used as a detection part. An image of a small amount of magnetic particles adsorbed in the detection part is taken every cycle of an analysis, and a light emission amount of the small amount of magnetic particles is acquired. A quantitative analysis of a substance to be analyzed is performed on the basis of an average light emission amount per one of the magnetic particles.
摘要翻译：要解决的问题：提供能够通过使用少量磁性颗粒来分析灵敏度和重复性优异的样品分析装置和样品分析方法。解决方案：使用平坦的基板作为检测部件。在每个分析周期中取出吸附在检测部分中的少量磁性颗粒的图像，并且获取少量磁性颗粒的发光量。基于每个磁性颗粒的平均发光量进行待分析物质的定量分析。

8. 发明专利

JP2010169455A Autosampler, liquid chromatograph, and valve 审中-公开
标题翻译：自动清洗机，液相色谱仪和阀门
公开(公告)号：JP2010169455A
公开(公告)日：2010-08-05
申请号：JP2009010485
申请日：2009-01-21
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： HARADA YUJI , DEGUCHI KISABURO
IPC分类号： G01N30/20 , G01N30/24 , G01N30/26 , G01N35/10
摘要： PROBLEM TO BE SOLVED: To provide an autosampler having less sample residues. SOLUTION: In this sampler, a path-switching valve 11 can switch a first state wherein a sample is held in a sample loop, by rotating a seal relative to a stator to/from a second state, wherein the sample held by the sample loop 17 is moved to the analytical column side by a mobile phase, and a groove through which the sample passes in a first state is the same as a groove, through which the sample and the mobile phase pass in a second state. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供具有较少样品残余物的自动进样器。解决方案：在该采样器中，路径切换阀11可以通过相对于定子将密封件旋转到第二状态而将样品保持在样品回路中的第一状态切换，其中样品保持在样品回路17通过流动相移动到分析柱侧，并且样品在第一状态下通过的槽与槽相同，样品和流动相通过该沟槽处于第二状态。版权所有（C）2010，JPO＆INPIT

9. 发明专利

JP2007121192A Liquid chromatographic apparatus 审中-公开
标题翻译：液相色谱仪
公开(公告)号：JP2007121192A
公开(公告)日：2007-05-17
申请号：JP2005316292
申请日：2005-10-31
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： KUBO SHINTARO , YOKOKURA TAKEFUMI , HARADA YUJI , ITO MASATO , MIURA JUNKICHI
IPC分类号： G01N30/26 , G01N30/34 , G01N30/86
摘要： PROBLEM TO BE SOLVED: To provide a liquid chromatographic apparatus that has a flow channel switching valve for switching between separation and connection between a sample suction channel system and an elution channel system including a pump, a separation column and a detector, and can shorten the transition time of mobile phase to the separation column and shorten the analysis time.
SOLUTION: In a sampling step, a valve 8 separates the flow channel between the pump 3 and separation column 5 and the sample suction system 7. In a sample injection step, the flow channel of the valve 8 is changed, the sample suction channel system 7 is connected to a gradient elution channel system, and a sample is introduced into the gradient channel system. In a gradient analysis step, the valve 8 is operated by the time when the mobile phase composition variation reaches valve 8, and the sample suction channel system 7 is separated from the gradient elution channel system. In the gradient analysis step, the sample suction channel system 7 is separated from the gradient elution channel system, and the mobile phase can be supplied to the separation column 5 without passing it via the sample suction channel system 7.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种液相色谱仪，其具有用于在样品吸入通道系统和包括泵，分离柱和检测器的洗脱通道系统之间的分离和连接之间切换的流路切换阀，以及可以缩短流动相到分离柱的转换时间，缩短分析时间。解决方案：在采样步骤中，阀8分离泵3和分离塔5与样品抽吸系统7之间的流动通道。在样品注入步骤中，阀8的流动通道改变，样品抽吸通道系统7连接到梯度洗脱通道系统，并将样品引入梯度通道系统。在梯度分析步骤中，阀8在流动相组成变化达到阀8时运行，样品吸入通道系统7与梯度洗脱通道系统分离。在梯度分析步骤中，将样品抽吸通道系统7与梯度洗脱通道系统分离，并且可以将流动相通过样品吸入通道系统7而不通过分离塔5供给流动相。 C）2007，JPO＆INPIT

10. 发明专利

JP2013190400A Autoanalyzer 审中-公开
标题翻译：自动加油
公开(公告)号：JP2013190400A
公开(公告)日：2013-09-26
申请号：JP2012058848
申请日：2012-03-15
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： HARADA YUJI , YAMASHITA YOSHIHIRO , SAKAZUME TAKU
IPC分类号： G01N35/00
摘要： PROBLEM TO BE SOLVED: To provide an autoanalyzer capable of suppressing deterioration of analysis efficiency by shortening time to stabilization of reagent temperature.SOLUTION: An autoanalyzer includes: a reagent constant temperature part 6a of a reagent constant temperature mechanism 6 which holds a reagent container 5 under predetermined fixed temperature environment; and a reagent temperature control part 21 which is provided in the reagent constant temperature mechanism 6, and holds the reagent container 5 under changeable temperature environment. The autoanalyzer conveys the reagent container 5 inside the reagent constant temperature mechanism 6 including the reagent temperature control part 21 by a reagent container conveyance mechanism 22, and controls temperature environment for holding the reagent container 5 of the reagent temperature control part 21 on the basis of a measurement result of a reagent temperature measurement mechanism 30.
摘要翻译：要解决的问题：提供能够通过缩短试剂温度稳定化的时间来抑制分析效率的劣化的自动分析仪。自动分析仪包括：试剂恒温机构6的试剂恒温部分6a，其保持试剂容器5 在预定的固定温度环境下; 以及试剂温度控制部21，其设置在试剂恒温机构6中，并且在可变温度环境下保持试剂容器5。自动分析器通过试剂容器搬运机构22将试剂容器5输送到包含试剂温度控制部21的试剂恒温机构6内，并且基于试剂温度控制部21的试剂容器5的保持温度环境试剂温度测定机构30的测定结果。

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