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1. 发明专利

JP2011232056A Apparatus and method for detecting change in membrane potential 有权
标题翻译：用于检测膜电位变化的装置和方法
公开(公告)号：JP2011232056A
公开(公告)日：2011-11-17
申请号：JP2010100284
申请日：2010-04-23
申请人： Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
发明人： SUGIYAMA NORIKAZU , KATAOKA TAKUJI , IKEDA TAKAHIRO
IPC分类号： G01N21/27 , G01N21/03
CPC分类号： G01N21/45 , C12Q1/02 , G01N21/253
摘要： PROBLEM TO BE SOLVED: To provide an apparatus and a method for detecting a change in a membrane potential capable of detecting the change in the membrane potential of a cell in a noninvasive method without labeling the cell membrane.SOLUTION: The apparatus for detecting the change in the membrane potential 1 includes: a light source 106 for reflection interference measurement; a holding section 103 for holding a transparent member 102a mounted with a cell 101; a camera 110 for reflection interference detection for imaging the reflected light which has been emitted from the light source 106 for reflection interference measurement and has been reflected from the cell 101 through the transparent member 102a to form a reflection interference image; and an analysis section 202 for calculating a parameter dI concerning adhesion between the cell 101 and the transparent member 102a from the reflection interference image and detecting the change in the membrane potential of the cell 101 based on the change in the parameter dI.
摘要翻译：要解决的问题：提供一种用于检测能够以非侵入性方法检测细胞膜电位变化而不标记细胞膜的膜电位变化的装置和方法。解决方案：用于检测膜电位1的变化的装置包括：用于反射干涉测量的光源106; 用于保持安装有单元101的透明构件102a的保持部103; 用于对从光源106发射的用于反射干涉测量的反射光成像的反射干涉检测用摄像机110，并通过透明构件102a从单元101反射，形成反射干涉图像; 以及分析部202，用于根据反射干涉图像计算关于单元101和透明构件102a之间的粘附的参数dI，并且基于参数dI的变化来检测单元101的膜电位的变化。版权所有（C）2012，JPO＆INPIT

2. 发明专利

JP2005195803A Three-dimensional image display device and three-dimensional image display method 有权
标题翻译：三维图像显示装置和三维图像显示方法
公开(公告)号：JP2005195803A
公开(公告)日：2005-07-21
申请号：JP2004001303
申请日：2004-01-06
申请人： Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
发明人： IKEDA TAKAHIRO , TAKEMORI TAMIKI
IPC分类号： G02B27/22 , G03H1/08 , G03H1/22
CPC分类号： G03H1/0841 , G03H1/08 , G03H1/2249 , G03H1/2294 , G03H2001/0858 , G03H2001/221 , G03H2210/30 , G03H2225/52
摘要： PROBLEM TO BE SOLVED: To provide a three-dimensional image display device, capable of displaying a high quality reconstructed image by making effective use of the focusing function of the observer's eyes, using a simple constitution.
SOLUTION: The interval between luminescent spots, constituting an objective reconstructed image to be displayed and/or an initial phase value, is set so that reproduce the light which reaches a region, where a reconstructed image by diffraction of a specific order in a spatial light modulating element 11 can be observed has a plurality of peak positions on a rear focal plane of a lens 12, and the spatial light modulating element 11 is made to exhibit a hologram, capable of displaying the objective reconstructed image. Illuminating light 90, incident on the spatial light modulation element 11 exhibiting the hologram, is amplitude- or phase-modulated at each pixel. This modulated light, that is, the reproduced light is subjected to wavefront conversion by the lens 12, whereby a reconstructed image is formed. An observer who locates the pupil of the eye near an aperture 13A in a mask 13 can observe the displayed reconstructed image 93 through the aperture 13A and a half mirror 15.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种三维图像显示装置，能够通过使用简单的结构有效利用观察者的眼睛的聚焦功能来显示高质量的重建图像。
解决方案：构成要显示的客观重建图像和/或初始相位值的发光点之间的间隔被设置为使得再现到达区域的光，其中通过衍射具有特定顺序的重建图像可以观察到空间光调制元件11在透镜12的后焦平面上具有多个峰值位置，并且使空间光调制元件11呈现出能够显示目标重建图像的全息图。入射到呈现全息图的空间光调制元件11上的照明光90在每个像素处进行幅度或相位调制。该被调制的光即再现光被透镜12进行波前转换，由此形成重构图像。在掩模13中靠近孔13A定位眼睛的瞳孔的观察者可以通过孔13A和半反射镜15观察所显示的重建图像93.（C）2005，JPO＆NCIPI

3. 发明专利

JP2004102075A Three-dimensional image display device and three- dimensional image display method 有权
公开(公告)号：JP2004102075A
公开(公告)日：2004-04-02
申请号：JP2002265935
申请日：2002-09-11
申请人： Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
发明人： TAKEMORI TAMIKI , IKEDA TAKAHIRO
IPC分类号： G02F1/13 , G02B27/22 , G03H1/08 , G03H1/22 , G03H1/24 , G03H1/26
CPC分类号： G03H1/2205 , G03H1/08 , G03H1/22 , G03H1/2249 , G03H1/2286 , G03H1/2294 , G03H1/24 , G03H2001/048 , G03H2001/221 , G03H2001/2263 , G03H2210/22 , G03H2210/30 , G03H2222/18 , G03H2222/34 , G03H2223/12 , G03H2223/19 , G03H2225/55
摘要： PROBLEM TO BE SOLVED: To provide a small-sized and inexpensive three-dimensional image display device which vividly displays three-dimensional images in color even when using a low-resolution spatial optical modulation element. SOLUTION: A three-dimensional image display device 1 is provided with an illuminating light source part 10, a lens 20, a transmissive spatial optical modulation element 30, a lens 40, and a mask 50. The illuminating light source part 10 has three point light sources which emit illuminating light of mutually different wavelengths (red, green and blue). The point light source which emits blue illuminating light of the shortest wavelength is placed in a position B(0, 0) on an optical axis of an illuminating optical system. The point light source which emits red illuminating light is placed in a position R(x r , 0). The point light source which emits green illuminating light is placed in a position G(x g , 0). An aperture part 51 of the mask 50 is provided in an area where respective 0th-order diffracted waves of reproducing light of three wavelengths have wave surfaces converted by the lens 40 and overlap one another. In order to realize this overlap, directions of incident on the spatial optical modulation element 30 of respective illuminating light of three wavelengths are set by the illuminating optical system. COPYRIGHT: (C)2004,JPO

4. 发明专利

JP2003005616A Method and device for creating computer hologram 有权
标题翻译：用于创建计算机HOLOGRAM的方法和装置
公开(公告)号：JP2003005616A
公开(公告)日：2003-01-08
申请号：JP2001185266
申请日：2001-06-19
申请人： Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
发明人： TAKEMORI TAMIKI , IKEDA TAKAHIRO
IPC分类号： G03H1/08 , G03H1/22
摘要： PROBLEM TO BE SOLVED: To provide a method and a device capable of creating at a high rate a computer hologram which permits reproducing a reproducing image of a high quality.
SOLUTION: Each intermediate luminescent spot is assumed in a ratio of the three intermediate luminescent spots (hatching applied positions) for each original luminescent spot (black painted out positions) respectively with regard to the plural original luminescent spots on the reproducing image on the target to be reproduced by the hologram. A propagation functional value is memorized in advance by the memory part for the propagation functional value. This is represented as the sum of the propagation functional value for the wave front of the light wave generated from either of the luminescent point on the reproducing image on the target plus the propagation functional value for the wave front of the light wave generated from a luminescent spot assumed at an intermediate position. A hologram value is calculated for each point of a picture element on the surface of the hologram. This calculation is accomplished under the propagation functional value memorized in advance by the memory part for the propagation functional value so that the computer hologram is created.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供能够以高速率创建允许再现高质量的再现图像的计算机全息图的方法和装置。解决方案：对于每个原始发光点的三个中间发光点（阴影施加位置）的比例，分别针对目标上的再现图像上的多个原始发光点，假定每个中间发光点被全息图复制。传播功能值由传播功能值的存储部件预先存储。这表示为从目标上再现图像上的发光点中的任一个产生的光波的传播功能值的和与由发光产生的光波的波前的传播函数值的和现场假设在中间位置。对全息图的表面上的像素的每个点计算全息值。该计算是在传播功能值的存储部件预先存储的传播功能值下完成的，从而创建计算机全息图。

5. 发明专利

JP2009148224A Specimen identification device and specimen identification method 有权
标题翻译：标本识别装置和样本识别方法
公开(公告)号：JP2009148224A
公开(公告)日：2009-07-09
申请号：JP2007330468
申请日：2007-12-21
申请人： Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
发明人： IKEDA TAKAHIRO , IWAI HIDENAO , YAMAUCHI TOYOHIKO
IPC分类号： C12M1/34 , C12M1/00 , C12Q1/02 , G01N33/48 , G02B21/00 , G06T1/00 , H04N7/18
CPC分类号： G02B21/365 , G02B21/368
摘要： PROBLEM TO BE SOLVED: To improve the work efficiency in the identification of a specimen having a desired oscillation state. SOLUTION: Provided is a cell stethoscope 1 having a specimen image inputting part 31 to input image information of a cell, an image displaying part 50 to display the image information to the observer, a region specifying part 40 to specify a definite region in the image information according to the operation by the observer based on the image information displayed on the image displaying part 50, a frequency conversion part 32 to perform the frequency conversion of the frequency information of the cell in the definite region specified by the region specifying part 40 to sound information, and a sound outputting part 60 to output the sound information obtained by the frequency conversion by the frequency conversion part 32 to the observer. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提高具有期望振荡状态的试样的识别中的工作效率。解决方案：提供一种细胞听诊器1，其具有用于输入单元的图像信息的标本图像输入部31，向观察者显示图像信息的图像显示部50，指定确定区域的区域指定部40 在基于图像显示部分50上显示的图像信息的根据观察者的操作的图像信息中，执行频率转换部分32，以执行由指定的区域指定的确定区域中的小区的频率信息的频率转换以及声音输出部60，用于将通过频率转换部32的频率变换获得的声音信息输出给观察者。版权所有（C）2009，JPO＆INPIT

6. 发明专利

JP2013088520A Observation device 有权
标题翻译：观察装置
公开(公告)号：JP2013088520A
公开(公告)日：2013-05-13
申请号：JP2011227119
申请日：2011-10-14
申请人： Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
发明人： IWAI HIDENAO , IKEDA TAKAHIRO
IPC分类号： G03H1/16 , G01N21/64 , G02B21/00 , G03H1/04 , G03H1/22
摘要： PROBLEM TO BE SOLVED: To provide an observation device capable of obtaining a fluorescent image of a moving object even when using an optical detector in which reading speed per one pixel is low, without blur with movement (motion blur), consequently, without deteriorating spatial resolution.SOLUTION: An observation device 1 includes: a light source portion 10; a first modulator 20; a second modulator 30; a lens 40; a beam splitter 41; an optical detector 46; and a computing portion 50. The lens 40 forms a Fourier transform image of an object 2 by inputting fluorescent light generated in the moving object 2. The optical detector 46 outputs data indicating a sum total in a v-direction of data changing timewise by a frequency corresponding to the Doppler shift amount of light reaching each position on a light receiving surface through the lens 40, at each time about each position in a u-direction. The computing portion 50 obtains an image of the object 2 on the basis of the output of the optical detector 46.
摘要翻译：要解决的问题：即使使用每一像素的读取速度低的光学检测器，即使没有运动模糊（运动模糊）也能够提供能够获得移动物体的荧光图像的观察装置，而不会降低空间分辨率。解决方案：观察装置1包括：光源部分10; 第一调制器20; 第二调制器30; 透镜40; 分束器41; 光学检测器46; 透镜40通过输入在移动物体2中产生的荧光，形成物体2的傅里叶变换图像。光检测器46输出表示数据变化的v方向上的总和的数据，频率对应于通过透镜40到达光接收表面上的每个位置的光的多普勒偏移量，每次在u方向上的每个位置处。计算部分50基于光学检测器46的输出获得对象2的图像。版权所有：（C）2013，JPO＆INPIT

7. 发明专利

JP2003345226A Device, system and method for image display 有权
标题翻译：用于图像显示的装置，系统和方法
公开(公告)号：JP2003345226A
公开(公告)日：2003-12-03
申请号：JP2002152998
申请日：2002-05-27
申请人： Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
发明人： IKEDA TAKAHIRO , TAKEMORI TAMIKI
IPC分类号： G03B35/00 , G02B27/22 , G03H1/22 , H04N13/04
摘要： PROBLEM TO BE SOLVED: To provide a small and inexpensive image display device capable of selectively displaying a three-dimensional image and a two-dimensional image by switching three-dimensional image display and two-dimensional image display and of displaying a high quality moving picture. SOLUTION: In three-dimensional image display, amplitude modulation in an amplitude modulating part 12a is set on the basis of amplitude information A3 included in three-dimensional image information supplied from a three- dimensional image information storage part 91, and phase modulation in a phase modulating part 12p is also set on the basis of phase information P3 included in the three-dimensional image information. In two-dimensional image display, amplitude modulation in the amplitude modulation part 12a is set on the basis of two-dimensional image information A2 supplied from a two-dimensional image information storage part 92, and phase modulation in the phase modulation part 12p is set on the basis of light scattering phase information P2 supplied from a light scattering phase information storage part 14. Illuminating light L emitted from an illuminating part 11 is made incident on a spatial light modulation element 12 to display a three-dimensional image G3 and a two-dimensional image G2. COPYRIGHT: (C)2004,JPO
摘要翻译：解决的问题：为了提供能够通过切换三维图像显示和二维图像显示并显示高的图像来选择性地显示三维图像和二维图像的小型且便宜的图像显示装置优质动态图片。解决方案：在三维图像显示中，基于从三维图像信息存储部分91提供的三维图像信息中包括的幅度信息A3设置幅度调制部分12a中的幅度调制，并且相位也基于包含在三维图像信息中的相位信息P3设定相位调制部12p的调制。在二维图像显示中，基于从二维图像信息存储部分92提供的二维图像信息A2设置幅度调制部分12a中的幅度调制，并且设置相位调制部分12p中的相位调制基于从光散射相位信息存储部分14提供的光散射相位信息P2。从照明部分11发射的照明光L入射到空间光调制元件12上以显示三维图像G3和二维数图像G2。版权所有（C）2004，JPO

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