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1. 发明授权

EP2669673B1 Bubble reduction device, chromotography device, bubble reduction method, and bubble reduction program 有权转让
公开(公告)号：EP2669673B1
公开(公告)日：2018-12-26
申请号：EP13169243.6
申请日：2013-05-24
申请人： ARKRAY, Inc.
发明人： Satake, Seiji , Kasai, Tokuo , Sezaki, Akira , Matsubara, Takeshi
IPC分类号： G01N30/26 , A61M1/36 , B01D15/16 , B01D19/00 , G01N30/20 , G01N30/24 , G01N30/32
CPC分类号： G01N30/06 , B01D15/16 , B01D19/0036 , B01D19/0063 , B01L3/502723 , G01N30/04 , G01N30/20 , G01N30/24 , G01N30/26 , G01N2030/322 , G01N2030/8822
摘要： A bubble reduction device, chromatography device, bubble reduction method and bubble reduction program capable of reducing bubbles in an eluent. Included are a liquid accommodation portion (12A), a liquid supply apparatus (63), an air layer formation apparatus (72), a first channel (14) and an evacuation portion (76). The liquid accommodation portion (12A) accommodates a liquid that is to elute an analysis component from a specimen adsorbed to an adsorption portion. The liquid supply apparatus (63), by operation of a rod (66) pushing up and pulling down, sucks and discharges the liquid through an aperture portion of a tube portion (65), the aperture portion being oriented upward. The air layer formation apparatus (72) forms an air layer in the tube portion (65). The first channel (14) connects the liquid supply apparatus (63) with the liquid accommodation portion (12A). The evacuation portion (76) is connected to the first channel (14) via a first switching valve (74) and evacuates the air layer through the first channel (14).

2. 发明授权

EP3123164B1 METHOD AND VALVE IN A CONTINUOUS CHROMATOGRAPHY SYSTEM 有权转让
公开(公告)号：EP3123164B1
公开(公告)日：2018-10-17
申请号：EP15712294.6
申请日：2015-03-16
申请人： GE Healthcare Bio-Sciences AB
发明人： OLOVSSON, Bjorn Markus
IPC分类号： G01N30/20 , B01D15/18 , F16K11/074 , G01N30/44 , G01N30/80
CPC分类号： G01N30/20 , B01D15/1842 , F16K11/0743 , G01N30/44 , G01N30/80 , G01N2030/202
摘要： A method and a rotary valve (65) in a continuous chromatography system. The rotary valve (65) comprises a stator (5) with an inner stator face (5a), and a rotor (12) with an inner rotor face (12a) arranged in sealing contact with the inner stator face (5a). The stator (5) comprises at least a first and a second inlet orifices (81,81), at least two first outlet (85a) orifices, a second outlet orifice (87) and a third outlet orifice (89), and the rotor interconnection paths are arranged to: - in at least one rotary position connect the first inlet orifice to the second outlet orifice and the second inlet orifice to the third outlet orifice, and - in at least two other rotary positions connect the first inlet orifice with any one of the first outlet orifices at the same time as the second inlet orifice is connected to the second outlet orifice.

3. 发明授权

EP3084420B1 CHROMATOGRAPHY SYSTEM COMPRISING A ROTARY VALVE AND A FEED RECIRCULATION FLOW PATH 有权转让
公开(公告)号：EP3084420B1
公开(公告)日：2018-10-17
申请号：EP14871221.9
申请日：2014-12-15
申请人： GE Healthcare Bio-Sciences AB
发明人： OLOVSSON, Bjorn
IPC分类号： G01N30/20 , F16K11/02 , F16K11/074 , G01N30/46
CPC分类号： G01N30/20 , B01D15/1842 , B01D2215/024 , F16K11/0743 , G01N30/466 , G01N2030/202
摘要： A rotary valve comprising a stator and a rotor wherein the stator comprises at least three inlet primary connection ports, at least three outlet primary connection ports, at least three inlet secondary connection ports and at least three outlet secondary connection ports, and wherein rotor interconnection paths are arranged to in the different rotor positions interconnect the inlet primary connection ports with the inlet secondary connection ports and the outlet primary connection ports with the outlet secondary connection ports such that all of at least three inlet secondary connection ports can be connected one at the time to each of at least three inlet primary connection port and all of at least three outlet secondary connection ports can be connected one at the time to each of at least three outlet primary connection port by rotating the rotor into the different rotor positions. A chromatography system comprising at least three chromatography columns, a rotary valve connected to the inlets of at least three columns in the system and to at least three inflows and connected to the outlets of at least three columns in the system and to at least three outflows, and a feed recirculation flow path.

4. 发明公开

EP3382388A1 SAMPLING METHOD FOR THE CHROMATOGRAPHIC ANALYSIS OF THE HEADSPACE 审中-公开
公开(公告)号：EP3382388A1
公开(公告)日：2018-10-03
申请号：EP18162743.1
申请日：2018-03-20
申请人： Thermo Fisher Scientific S.p.A
发明人： MAGNI, Paolo , PELAGATTI, Stefano , FACCHETTI, Riccardo , SCAGLIONE, Antonio
IPC分类号： G01N30/20 , G01N1/22 , G01N30/18
CPC分类号： G01N30/20 , G01N1/2226 , G01N30/18 , G01N2001/2229 , G01N2030/025 , G01N2030/202 , G01N2030/207
摘要： The invention concerns a method for preparing a sample to be introduced in a chromatographic analysis system from the headspace of a vial, by introducing a pressurized inert gas in said headspace, controlling the pressure or flow, and subsequently by discharging said pressure from the headspace through a loop having constant volume and through a discharge duct provided with a valve, the discharge duct branching with respect to the feed duct. To eliminate the drawbacks of the known methods, during the step of discharging the pressure, the feed duct is kept open and the pressure in said loop is controlled by detecting the feed and/or discharge pressure.

5. 发明公开

EP3368892A1 COUPLED ANALYTICAL INSTRUMENTS FOR DUAL MODE FTIR/GC-FTIR 审中-公开
公开(公告)号：EP3368892A1
公开(公告)日：2018-09-05
申请号：EP16794833.0
申请日：2016-10-27
申请人： MAX Analytical Technologies, Inc.
发明人： SPARTZ, Martin L. , BONANNO, Anthony S. , BEHNKE, Peter P.
IPC分类号： G01N30/74 , G01N30/20 , G01N33/00
CPC分类号： G01N30/74 , G01N30/06 , G01N30/20 , G01N30/30 , G01N30/38 , G01N2030/025 , G01N2030/085 , G01N2030/201 , G01N2030/202 , G01N2030/743 , G01N2030/8886
摘要： A system and method are disclosed for analyzing samples, which includes a spectrometry system for detecting components of a sample; a gas chromatography column for separating the components of a sample; a first sample unit for receiving a first sample from a sample source; and a second sample unit for receiving a second sample from a sample source. Each sample loop unit allows independent processing of samples in preparation for analysis.

6. 发明公开

EP3241021A1 VALVE MANIFOLDS FOR SIMULATED MOVING BED CHROMATOGRAPHY 有权转让
标题翻译：用于模拟移动床色谱的阀门流路
公开(公告)号：EP3241021A1
公开(公告)日：2017-11-08
申请号：EP15822943.5
申请日：2015-12-23
申请人： GE Healthcare Bio-Sciences AB
发明人： GEBAUER, Klaus , OLOVSSON, Bjorn Markus
IPC分类号： G01N30/20 , B01D15/18 , G01N30/88 , G01N30/42
CPC分类号： B01D15/1842 , G01N30/20 , G01N30/42 , G01N30/88 , G01N2030/205 , G01N2030/8881
摘要： Go between a first portion of the central duct and an opposed second portion of the central duct, a first plurality of connectors, each connector of the first plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; a second plurality of connectors, each connector of the second plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; wherein said manifold body further defines: a first plurality of branch ducts, each branch duct of which extending from the first portion of the central duct to an individual one of the first plurality of connectors, each of the branch ducts of the first plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the first portion of the central duct, a second plurality of branch ducts, each branch duct of which extending from the second portion of the central duct to an individual one of the second plurality of connectors, each of the branch ducts of the second plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the second portion of the central duct; first and second ports in fluid communication with the centrally-located closable duct valve wherein said first port communicates with said first portion of the central duct and said second port communicates with said second portion of said central duct, wherein one of said first and second ports is further positioned to communicate with said central duct at a location between the centrally-located closable duct valve and the first and second plurality of branch ducts, respectively.

7. 发明公开

EP3227674A1 MICRODISPOSITIF DE DÉTECTION DE COMPOSÉS ORGANIQUES VOLATILS ET MÉTHODE DE DÉTECTION D'AU MOINS UN COMPOSÉ ORGANIQUE VOLATIL COMPRIS DANS UN ÉCHANTILLON GAZEUX 审中-公开
标题翻译： MICRODISPOSITIF DEDÉTECTIONDECOMPOSÉSORGANIQUES VOLATILS ETMÉTHODEDEDÉTECTIOND'AU MOINS UNCOMPOSÉORGANIQUE VOLATIL COMPRIS DANS UNÉCHANTILLONGAZEUX
公开(公告)号：EP3227674A1
公开(公告)日：2017-10-11
申请号：EP15817479.7
申请日：2015-12-04
申请人： Université de Strasbourg , Centre National de la Recherche Scientifique
发明人： LE CALVE, Stéphane , NASREDDINE, Rouba , PERSON, Vincent , SERRA, Christophe
IPC分类号： G01N33/00 , G01N30/60
CPC分类号： G01N30/02 , G01N30/20 , G01N30/62 , G01N30/88 , G01N33/0047 , G01N2030/0095 , G01N2030/025 , G01N2030/085 , G01N2030/884
摘要： The present invention relates to a micro-device for detecting volatile compounds. Said micro-device includes: - an inlet (E) and an outlet (S); - means (2) for collecting a gas sample containing at least one compound to be detected; - sampling means for sampling a volume of gas of less than or equal to 100 mL arranged after the collecting means; - means (3) for injecting said gas sample; - means (6) for detecting the compound; and - a gas flow system (1) located downstream from the collecting means and passing through the sampling means, the injection means (3), the separation means (5), and the detection means (6). Said micro-device is characterized in that the gas flow system (1) has a volume between 0.2 cm
3 and 2.0 cm
3 .
摘要翻译：本发明涉及用于检测挥发性化合物的微型装置。所述微器件包括： - 入口（E）和出口（S）; - 用于收集含有至少一种待检测化合物的气体样品的装置（2） - 取样装置，用于取样布置在所述收集装置之后的小于或等于100mL的气体体积; - 用于注入所述气体样本的装置（3） - 用于检测化合物的装置（6）和 - 位于收集装置下游并穿过采样装置，注入装置（3），分离装置（5）和检测装置（6）的气体流动系统（1）。所述微型装置的特征在于气体流动系统（1）具有在0.2cm 3与2.0cm 3之间的体积。

8. 发明公开

EP3090259A4 HEATED ROTARY VALVE FOR CHROMATOGRAPHY 有权
标题翻译： BEHEIZTES DREHVENTILFÜRDIE CHROMATOGRAFIE
公开(公告)号：EP3090259A4
公开(公告)日：2017-07-12
申请号：EP14877217
申请日：2014-12-26
申请人： VALCO INSTR COMPANY L P
发明人： STEARNS STANLEY D , BRISBIN MARTIN PAUL , MILLER DAVID
IPC分类号： G01N30/20
CPC分类号： F16K49/002 , F16K11/076 , F16K11/085 , G01N30/20 , G01N2030/202 , G01N2030/3053 , Y10T137/6416 , Y10T137/6606
摘要： A heated rotary valve for use in connection with a sample to be separated in a column for heating the sample to temperature within the valve. The heated rotary valve permits introduction of compounds, having a wide boiling range, into a gas chromatograph with improved precision of area and retention time. The valve includes a stator, an elongate body, a rotor seal, a drive shaft, and an internal element for generating heat. The rotor seal may be laterally captured by a ring to prevent movement or creep due to heat absorption during operation.
摘要翻译：一个加热旋转阀，用于连接样品，在柱中分离，用于将样品加热到阀内的温度。加热旋转阀允许将具有宽沸程的化合物引入具有改进的面积精度和保留时间的气相色谱仪中。该阀包括定子，细长体，转子密封件，驱动轴和用于产生热量的内部元件。转子密封件可以被环侧向地捕获以防止在操作期间由于吸热而移动或蠕变。

9. 发明授权

EP2362214B1 SAMPLE INJECTION DEVICE, SAMPLE INJECTION METHOD, AND LIQUID CHROMATOGRAPHY DEVICE 有权
标题翻译： PROBENINJEKTIONSVORRICHTUNG，PROBENINJEKTIONSVERFAHREN UND VORRICHTUNG ZURFLÜSSIGKEITSCHROMATOGRAPHIE
公开(公告)号：EP2362214B1
公开(公告)日：2017-03-01
申请号：EP09802941.6
申请日：2009-07-28
申请人： Shiseido Company, Ltd.
发明人： HIRAYAMA, Aya , SHIROTA, Osamu , MITA, Masashi , MIBAYASHI, Kazuhiko
IPC分类号： G01N30/16 , G01N30/20 , G01N30/24 , F16K11/00 , G01N35/10
CPC分类号： G01N30/20 , G01N30/16 , G01N30/24 , G01N35/1004 , G01N35/1097

10. 发明公开

EP3123164A1 METHOD AND VALVE IN CONTINUOUS CHROMATOGRAPHY SYSTEM 有权转让
标题翻译： VERFAHREN通风系统ZUR KONTINUIERLICHEN CHROMATOGRAPHIE
公开(公告)号：EP3123164A1
公开(公告)日：2017-02-01
申请号：EP15712294.6
申请日：2015-03-16
申请人： GE Healthcare Bio-Sciences AB
发明人： OLOVSSON, Bjorn Markus
IPC分类号： G01N30/20 , B01D15/18 , F16K11/074 , G01N30/44 , G01N30/80
CPC分类号： G01N30/20 , B01D15/1842 , F16K11/0743 , G01N30/44 , G01N30/80 , G01N2030/202
摘要： A method and a rotary valve (65) in a continuous chromatography system. The rotary valve (65) comprises a stator (5) with an inner stator face (5a), and a rotor (12) with an inner rotor face (12a) arranged in sealing contact with the inner stator face (5a). The stator (5) comprises at least a first and a second inlet orifices (81,81), at least two first outlet (85a) orifices, a second outlet orifice (87) and a third outlet orifice (89), and the rotor interconnection paths are arranged to: - in at least one rotary position connect the first inlet orifice to the second outlet orifice and the second inlet orifice to the third outlet orifice, and - in at least two other rotary positions connect the first inlet orifice with any one of the first outlet orifices at the same time as the second inlet orifice is connected to the second outlet orifice.
摘要翻译：连续色谱系统中的方法和旋转阀（65）。旋转阀（65）包括具有内定子面（5a）的定子（5）和具有与内定子面（5a）密封接触的内转子面（12a）的转子（12）。定子（5）至少包括第一和第二入口孔口（81,81），至少两个第一出口孔口（85a），第二出口孔口（87）和第三出口孔口（89），转子互连路径被布置成： - 在至少一个旋转位置中，将第一入口孔连接到第二出口孔，将第二入口孔连接到第三出口孔，并且 - 在至少两个其它旋转位置中，将第一入口孔与任何与第二入口孔同时的第一出口孔中的一个连接到第二出口孔。

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