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1. 发明授权

EP2114823B1 LIQUID-CHROMATOGRAPHY APPARATUS HAVING DIFFUSION-BONDED TITANIUM COMPONENTS 有权转让
标题翻译：具有扩散结合钛组分的液相色谱仪
公开(公告)号：EP2114823B1
公开(公告)日：2018-01-03
申请号：EP08731008.2
申请日：2008-02-28
申请人： Waters Technologies Corporation
发明人： DOURDEVILLE, Theodore, A.
IPC分类号： B23K20/02 , G01N30/30 , C01B15/00 , C11D11/00 , C25B1/00
CPC分类号： G01N30/606 , B23K20/023 , B23K20/233 , B23K20/24 , B23K2101/14 , B23K2103/14 , G01N30/20 , G01N30/6095 , G01N2030/201 , G01N2030/202
摘要： A rotary-shear-seal valve, comprising a stator assembly (1700) comprising an external-plumbing interface portion (1710) comprising a metal, and defining at least two tubing ports, a gasket (1721) comprising said metal and diffusion bonded to said external-plumbing interface portion (1710), wherein the gasket defines a fluid circuit for each of the tubing ports, an outer end of each fluid circuit being in fluid communication with a corresponding one of the tubing ports, and a rotor-interface portion (1720) having a surface configured to mate with a rotor of the rotary-shear valve.

2. 发明公开

EP3234587A1 ROTARY VALVE AND SYSTEMS 有权转让
标题翻译：旋转阀和系统
公开(公告)号：EP3234587A1
公开(公告)日：2017-10-25
申请号：EP15808155.4
申请日：2015-12-10
申请人： GE Healthcare Bio-Sciences AB
发明人： OLOVSSON, Bjorn, Markus , ERIKSSON, Christer Olof
IPC分类号： G01N30/20 , F16K11/074 , B01D15/18
CPC分类号： F16K11/0836 , F16K11/0743 , F16K31/041 , G01N30/20 , G01N2030/201 , G01N2030/202
摘要： A rotary valve 1 comprising a stator 3 and a rotor 5, wherein the stator comprises a plurality of connection ports (17a-17l) and orifices (19a-19l) and the rotor comprises a plurality of pairs of rotor valve orifices (23a-23h) joined by transfer channels (25a-25d). The rotor is able to be placed in different working positions whereby fluids can be fed to, for example, chromatography columns and/or can be bypassed through or around the valve. The invention also relates to a system comprising two components such as chromatography columns and a rotary valve.
摘要翻译：包括定子3和转子5的旋转阀1，其中定子包括多个连接端口（17a-17l）和孔口（19a-19l），并且转子包括多对转子阀孔（23a-23h ）由传送通道（25a-25d）连接。转子能够被放置在不同的工作位置，由此流体可以被供给到例如色谱柱和/或可以绕过阀或绕过阀。本发明还涉及包括两个组件的系统，例如色谱柱和旋转阀。

3. 发明授权

EP2121188B1 Rotary injection valve for a chromatography system 有权
标题翻译：用于色谱系统的旋转注射阀
公开(公告)号：EP2121188B1
公开(公告)日：2017-05-24
申请号：EP08724750.8
申请日：2008-01-24
申请人： Teledyne Instruments, Inc.
发明人： DAVISON, Dale, A.
IPC分类号： G01N30/20 , B01L3/02 , F16K11/074 , G01N35/10
CPC分类号： G01N30/20 , G01N35/1097 , G01N2030/201 , G01N2030/202 , Y10T137/86541

4. 发明公开

EP2990791A4 SWITCHING VALVE FOR FLOW-TYPE ANALYSIS DEVICE 有权
标题翻译： SCHALTVENTILFÜREINESTRÖMUNGSANALYSEVORRICHTUNG
公开(公告)号：EP2990791A4
公开(公告)日：2017-01-04
申请号：EP14788272
申请日：2014-04-22
申请人： SEKISUI MEDICAL CO LTD
发明人： YOTANI TAKUYA , TAIRA HIROAKI , OKA TAKAYUKI , MURAKI HIDEKI
IPC分类号： G01N30/26 , G01N1/00 , G01N30/20 , G01N35/10
CPC分类号： G01N30/20 , G01N33/491 , G01N35/1097 , G01N2030/201 , G01N2030/202 , G01N2030/207
摘要： Provided is a switching valve including the following (A) to (C): (A) a rotor including the following (1) to (3): (1) a center pipe connection port, (2) a first in-valve flow path in communication with the center pipe connection port, and (3) an arc-like second in-valve flow path; (B) a stator including the following (4) and (5): (4) a first pipe connection port group which is brought into communication independently with the center pipe connection port via the first in-valve flow path when the rotor is turned, and (5) a second pipe connection port group which is brought into mutual communication via the second in-valve flow path when the rotor is turned; and (C) an arrangement of the rotor and the stator which satisfies the following relationship: the state of communication or non-communication among the second pipe connection port group via the second in-valve flow path is switched in accordance with the state of communication between the first pipe connection port group and the center pipe connection port.
摘要翻译：本发明提供一种包括以下（A）至（C）的切换阀：（A）包括以下（1）至（3）的转子：（1）中心管连接口，（2）与中心管连接口连通的路径，（3）弧形第二阀内流路; （B）包括以下（4）和（5）的定子：（4）第一管连接口组，当转子转动时，第一管连接口组通过第一通阀流路与中心管连接口独立连通和（5）第二管连接口组，当转子转动时，第二管连接口组通过第二通阀流路相互连通; 和（C）转子和定子的结构，其满足以下关系：根据通信状态来切换第二管连接端口组之间经由第二进气门流路的通信状态或非通信状态在第一管连接端口组和中心管连接端口之间。

5. 发明授权

EP2257356B1 CHROMATOGRAPHY-BASED MONITORING AND CONTROL OF MULTIPLE PROCESS STREAMS 有权
标题翻译： AUF CHROMATOGRAPHIE BERUHENDEÜBERWACHUNGUND STEERER MEHRERERPROZESSSTRÖME
公开(公告)号：EP2257356B1
公开(公告)日：2016-12-14
申请号：EP09717552.5
申请日：2009-02-25
申请人： Waters Technologies Corporation
发明人： CORMIER, Sylvain
IPC分类号： B01D15/08 , G01N30/16 , G01N1/00 , G01N35/10
CPC分类号： G01N30/20 , G01N30/16 , G01N30/38 , G01N35/10 , G01N35/1097 , G01N2001/2893 , G01N2030/042 , G01N2030/201 , G01N2030/202 , G01N2030/207 , G01N2030/385 , Y10T436/10 , Y10T436/2575

6. 发明授权

EP1338894B1 Mobile phase gradient generation microfluidic device 有权
标题翻译：流动相梯度生成微流体装置
公开(公告)号：EP1338894B1
公开(公告)日：2016-07-20
申请号：EP03251113.1
申请日：2003-02-25
申请人： Agilent Technologies, Inc.
发明人： Yin, Hongfeng , Killeen, Kevin , Sobek, Daniel
IPC分类号： G01N30/34
CPC分类号： G01N30/34 , G01N30/6095 , G01N2030/201 , G01N2030/202 , G01N2030/285

7. 发明公开

EP2702303A2 VALVES HAVING PROTECTIVE COATINGS 审中-公开
标题翻译：通气麻省理工学院
公开(公告)号：EP2702303A2
公开(公告)日：2014-03-05
申请号：EP12776051.0
申请日：2012-04-20
申请人： Waters Technologies Corporation
发明人： CHEN, Carl, Gang , JENCKS, Robert, A. , LU, Wen , MOELLER, Mark, W.
IPC分类号： F16K25/04
CPC分类号： F16K25/005 , C23C14/0605 , F16K11/0655 , F16K11/0743 , G01N30/16 , G01N30/20 , G01N2030/201 , G01N2030/202 , G01N2030/207 , Y10T137/86638 , Y10T137/86863
摘要： A shear valve for use in a high performance liquid chromatography system. The shear valve includes a first valve member having a plurality of first fluid-conveying features, and a second valve member having one or more second fluid-conveying features. The second valve member is movable, relative to the first valve member, between a plurality of discrete positions such that, in each of the discrete positions, at least one of the one or more second fluid- conveying features overlaps with multiple ones of the first fluid conveying features to provide for fluid communication therebetween. At least one of the first and second valve members is at least partially coated with a protective coating that includes an adhesion interlayer and a diamond-like carbon (DLC) layer. The DLC layer is deposited on the adhesion interlayer via filtered cathodic vacuum arc (FCVA) deposition.
摘要翻译：用于高效液相色谱系统的剪切阀。剪切阀包括具有多个第一流体输送特征的第一阀构件和具有一个或多个第二流体输送特征的第二阀构件。第二阀构件可相对于第一阀构件在多个离散位置之间移动，使得在每个离散位置中，一个或多个第二流体输送特征中的至少一个与第一流体输送特征中的多个位置重叠流体输送特征以提供其间的流体连通。第一和第二阀构件中的至少一个至少部分地涂覆有包括粘合中间层和类金刚石碳（DLC）层的保护涂层。通过过滤阴极真空电弧（FCVA）沉积将DLC层沉积在粘附中间层上。

8. 发明公开

EP2681547A1 VENTIL MIT VERFORMBAREM TEIL UND VERWENDUNG DES VENTILS 无效转让
公开(公告)号：EP2681547A1
公开(公告)日：2014-01-08
申请号：EP12718557.7
申请日：2012-03-01
申请人： Artner, Christoph
发明人： SCHUBERT, Michael , BUSCH, Reinhard , NADER, Michael
IPC分类号： G01N30/20 , F16K11/074 , F16K11/076 , F16K15/14 , G01N35/10
CPC分类号： F16K11/00 , F16K11/0743 , G01N30/20 , G01N30/26 , G01N35/1097 , G01N2030/201 , G01N2030/202 , Y10T137/86493
摘要： The invention relates to a valve, in particular a sample injection valve, for a device (1) for synthesizing, analyzing, and/or separating, comprising at least three liquid connections (3', 4', 5', 6', 7', 7"), a housing (8) as a valve part, and a valve body (9) as another valve part for selectively connecting the liquid connections (3', 4', 5', 6', 7', 7") by means of at least one flow channel (10, 11, 12) bounded at least partially by sealing surfaces (10', 11', 12') between the housing (8) and the valve body (9), wherein the housing (8) and/or the valve body (9) are supported in such a way as to be movable relative to each other. In order to a create a one-way valve, at least one valve part (8 or 9) adjacent to the sealing surface (10', 11', 12') and made of a plastic material can be plastically deformed according to a relative position (9'), in particular of the valve body (9), in order to be able to withstand the elevated pressure loads in the flow channel (10, 11, 12) in a liquid-tight manner in said relative position (9'), in particular of the valve body (9).
摘要翻译：本发明涉及用于合成，分析和/或分离的装置（1）的阀，特别是样品注射阀，其包括至少三个液体连接（3'，4'，5'，6'，7 '，7“），作为阀部的壳体（8）和作为用于选择性地连接液体连接（3'，4'，5'，6'，7'，7'）的另一个阀部分的阀体 “）通过至少部分地由壳体（8）和阀体（9）之间的密封表面（10'，11'，12'）限定的至少一个流动通道（10,11,12）壳体（8）和/或阀体（9）以相对于彼此可移动的方式被支撑。为了形成单向阀，与密封表面（10'，11'，12'）相邻并且由塑料材料制成的至少一个阀部件（8或9）可以根据相对位置塑性变形（9'），特别是阀体（9），以便能够以相对位置（9'）以液密方式承受流道（10,11,12）中的升高的压力负荷，特别是阀体（9）），特别是阀体（9）。

9. 发明公开

EP2577287A1 METHOD AND INSTRUMENTATION FOR COMPREHENSIVE MULTIDIMENSIONAL CHROMATOGRAPHY SEPARATIONS USING A MICRO FLOW MODULATOR 有权转让
标题翻译：方法和手段综合多维色谱分离用微流调节器
公开(公告)号：EP2577287A1
公开(公告)日：2013-04-10
申请号：EP11722783.5
申请日：2011-05-24
申请人： Mondello, Luigi
发明人： Mondello, Luigi
IPC分类号： G01N30/46 , G01N30/32
CPC分类号： B01D53/02 , G01N30/32 , G01N30/463 , G01N30/465 , G01N30/6034 , G01N30/6039 , G01N30/7206 , G01N2030/201 , G01N2030/3084 , G01N2030/324
摘要： The present invention refers to a modulator, to be used for comprehensive multidimensional chromatography separations, to entrap and release sample solute fractions (entrapped in a capillary loop of fixed or variable volume), deriving from a capillary column with an internal diameter ranging from 0.01 mm to 0.53 mm, onto another capillary column with an internal diameter ranging from 0.01 mm to 0.53 mm. The micro-device has been integrated in a gas chromatographic system, composed of two ovens for the independent temperature control of the two columns; the micro-device is characterized, internally, by a system of channels that enable the controlled splitting of gas flow, entering the second capillary, to generate an optimum gas linear velocity and to release the pressure in excess, with the objective of attaining the maximum separation efficiency in the second column. Furthermore, the system is equipped with a second device, to divide the flow exiting the second column in two different detectors that operate at the same or at different pressures.

10. 发明公开

EP2374008A1 AUTOMATED SAMPLE INJECTION APPARATUS, MULTIPORT VALVE, AND METHODS OF MAKING AND USING THE SAME 审中-公开
标题翻译：为生产和使用自动进样设备的详细阀和方法
公开(公告)号：EP2374008A1
公开(公告)日：2011-10-12
申请号：EP09832239.9
申请日：2009-12-10
申请人： Alltech Associates Inc.
发明人： ANDERSON, James, M., Jr. , BYSTRON, Josef, P. , MENDOZA, Washington, J. , SAARI-NORDHAUS, Raaidah , PICHA, Neil , BLACK, Bruce
IPC分类号： G01N35/10
CPC分类号： G01N30/24 , G01N30/20 , G01N35/00732 , G01N2030/201 , G01N2035/0493 , Y10T29/49826 , Y10T137/86493
摘要： Automated sample injection apparatus, multiport valves, and chromatography systems containing an automated sample injection apparatus and/or a multiport valve are disclosed. Methods of making and using automated sample injection apparatus and multiport valves within chromatography systems are also disclosed.

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