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1. 发明授权

EP2924122B1 1,4-BUTANEDIOL MANUFACTURING METHOD AND MICROORGANISM 有权
标题翻译： 1,4-丁二醇制造方法和微生物
公开(公告)号：EP2924122B1
公开(公告)日：2017-08-23
申请号：EP13856298.8
申请日：2013-09-13
申请人： Showa Denko K.K.
发明人： AOKI, Hirobumi , KOKIDO, Yuzuru , HASHIMOTO, Yoko , YONEDA, Tadashi
IPC分类号： C12P7/18 , C12N1/19 , C12N1/21 , C12N15/09 , C12N9/04 , C12N9/02 , C12N9/88 , C12N9/90 , C12N15/52
CPC分类号： C12P7/18 , C12N9/0006 , C12N9/0008 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y101/01035 , C12Y101/01036 , C12Y101/01157 , C12Y102/0101 , C12Y402/01017 , C12Y402/01055 , C12Y402/01119 , C12Y402/0112 , C12Y503/03003

2. 发明公开

EP2924122A4 1,4-BUTANEDIOL MANUFACTURING METHOD AND MICROORGANISM 有权
标题翻译： 1,4-BANDANDIOL-HERSTELLUNGSVERFAHREN UND MIKORORGANISMUS
公开(公告)号：EP2924122A4
公开(公告)日：2016-05-11
申请号：EP13856298
申请日：2013-09-13
申请人： SHOWA DENKO KK
发明人： AOKI HIROBUMI , KOKIDO YUZURU , HASHIMOTO YOKO , YONEDA TADASHI
IPC分类号： C12P7/18 , C12N1/19 , C12N1/21 , C12N9/02 , C12N9/04 , C12N9/88 , C12N9/90 , C12N15/09 , C12N15/52
CPC分类号： C12P7/18 , C12N9/0006 , C12N9/0008 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y101/01035 , C12Y101/01036 , C12Y101/01157 , C12Y102/0101 , C12Y402/01017 , C12Y402/01055 , C12Y402/01119 , C12Y402/0112 , C12Y503/03003

3. 发明公开

EP2930239A1 1,4-BUTANEDIOL PRODUCTION METHOD, MICROORGANISM, AND GENE 审中-公开
标题翻译：法生产1,4-丁二醇，微生物及GEN
公开(公告)号：EP2930239A1
公开(公告)日：2015-10-14
申请号：EP13859911.3
申请日：2013-11-28
申请人： Showa Denko K.K.
发明人： AOKI, Hirobumi , KOKIDO, Yuzuru , HASHIMOTO, Yoko , YONEDA, Tadashi
IPC分类号： C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P7/18
CPC分类号： C12P7/18 , C12N9/0006 , C12N9/1029 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y101/01035 , C12Y101/01036 , C12Y101/01157 , C12Y203/01009 , C12Y402/01017 , C12Y402/01055 , C12Y402/01119 , C12Y402/0112 , C12Y503/03003
摘要： A method of manufacturing 1,4-butanediol through acetyl-CoA, acetoacetyl-CoA, 3-hydroxybutyryl-CoA, crotonyl-CoA, and 4-hydroxybutyryl-CoA by using a microbe and/or a culture thereof, wherein the microbe in the manufacturing method for 1,4-butanediol includes any one of genes among (a) a gene that has a base sequence of sequence number 1, (b) a gene that has a base sequence such that one or more bases are deleted, substituted, or added in a base sequence of sequence number 1, wherein the gene has a base sequence with an identity greater than or equal to 90% with respect to the base sequence of sequence number 1, and (c) a gene that hybridizes with a gene that has a base sequence complementary with a gene that has a base sequence described in sequence number 1 on a stringent condition, and includes any one or more genes among (d) genes that have base sequences of sequence numbers 2 to 9, (e) genes that have base sequences such that one or more bases are deleted, substituted, or added in base sequences of sequence numbers 2 to 9, wherein the genes have base sequences with an identity greater than or equal to 90% with respect to original base sequences thereof, and (f) genes that hybridize with genes that have base sequences complementary with genes that have base sequences of sequence numbers 2 to 9 on a stringent condition.

4. 发明公开

EP2930239A4 1,4-BUTANEDIOL PRODUCTION METHOD, MICROORGANISM, AND GENE 审中-公开
标题翻译： FUR HERSTELLUNGSVERFAHREN 1,4-丁二醇，Mikroorganismus UND JAN
公开(公告)号：EP2930239A4
公开(公告)日：2016-06-29
申请号：EP13859911
申请日：2013-11-28
申请人： SHOWA DENKO KK
发明人： AOKI HIROBUMI , KOKIDO YUZURU , HASHIMOTO YOKO , YONEDA TADASHI
IPC分类号： C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P7/18
CPC分类号： C12P7/18 , C12N9/0006 , C12N9/1029 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y101/01035 , C12Y101/01036 , C12Y101/01157 , C12Y203/01009 , C12Y402/01017 , C12Y402/01055 , C12Y402/01119 , C12Y402/0112 , C12Y503/03003
摘要： A method of manufacturing 1,4-butanediol through acetyl-CoA, acetoacetyl-CoA, 3-hydroxybutyryl-CoA, crotonyl-CoA, and 4-hydroxybutyryl-CoA by using a microbe and/or a culture thereof, wherein the microbe in the manufacturing method for 1,4-butanediol includes any one of genes among (a) a gene that has a base sequence of sequence number 1, (b) a gene that has a base sequence such that one or more bases are deleted, substituted, or added in a base sequence of sequence number 1, wherein the gene has a base sequence with an identity greater than or equal to 90% with respect to the base sequence of sequence number 1, and (c) a gene that hybridizes with a gene that has a base sequence complementary with a gene that has a base sequence described in sequence number 1 on a stringent condition, and includes any one or more genes among (d) genes that have base sequences of sequence numbers 2 to 9, (e) genes that have base sequences such that one or more bases are deleted, substituted, or added in base sequences of sequence numbers 2 to 9, wherein the genes have base sequences with an identity greater than or equal to 90% with respect to original base sequences thereof, and (f) genes that hybridize with genes that have base sequences complementary with genes that have base sequences of sequence numbers 2 to 9 on a stringent condition.
摘要翻译：通过使用微生物和/或其培养物，通过乙酰辅酶A，乙酰乙酰辅酶A，3-羟基丁酰基-CoA，巴豆酰基-CoA，和4-羟基丁酰-CoA的制造1,4-丁二醇的方法，其中，在所述微生物对于1,4-丁二醇的制造方法包括：间基因之一年（a）该基因具有序列号1的碱基序列，（b）将所述基因具有的碱基序列，例如阙一个或多个碱基缺失，取代，或在序列号1的碱基序列，其中所述基因具有大于或等于90％，相对于序列号1的碱基序列的同一性的碱基序列，和（c）的基因阙与基因杂交加入具有与阙对严格条件在序列号1中记载的碱基序列的基因互补的碱基序列，并且包括其中（d）中的基因的任何一种或多种基因阙具有2至9的序列号的碱基序列，（e）中该基因具有的碱基序列，例如阙一个或多个碱基缺失，取代，或添加在序列编号2〜9，其中，所述基因具有的碱基序列具有标识大于或等于90％，相对于它的原始碱基序列，和（f）的基因阙与基因杂交阙具有基因阙互补的碱基序列的碱基序列有序列号在严格条件2〜9的碱基序列。

5. 发明公开

EP3030668A1 METHODS FOR BIOSYNTHESIS OF ISOBUTENE 审中-公开
标题翻译：方法生物合成异丁烯
公开(公告)号：EP3030668A1
公开(公告)日：2016-06-15
申请号：EP14761439.0
申请日：2014-08-05
申请人： Invista Technologies S.A R.L.
发明人： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck
IPC分类号： C12P5/02 , C12N15/66
CPC分类号： C12P5/026 , C12N9/13 , C12N9/16 , C12N9/88 , C12Y208/02 , C12Y301/02 , C12Y301/02004 , C12Y401/01033 , C12Y402/01017 , C12Y402/01119
摘要： The document provides methods for biosynthesizing isobutene using one or more isolated enzymes such as one or more of a hydratase such as an enzyme classified under EC 4.2.1.- and a decarboxylating thioesterase, or using recombinant host cells expressing one or more such enzymes.

6. 发明公开

EP3218505A1 METHODS AND MATERIALS FOR PRODUCING 6-CARBON MONOMERS 审中-公开
标题翻译：生产6-碳单体的方法和材料
公开(公告)号：EP3218505A1
公开(公告)日：2017-09-20
申请号：EP15804257.2
申请日：2015-11-13
申请人： Invista Technologies S.à r.l.
发明人： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck , KADI, Nadia
IPC分类号： C12P7/42 , C12P13/00 , C12P7/18 , C12P7/44 , C12P17/10 , C12N9/10
CPC分类号： C12P19/32 , C07C47/12 , C07C47/19 , C07C225/06 , C07C229/08 , C07C233/31 , C07F9/65616 , C12N9/0006 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/1096 , C12N9/88 , C12N15/52 , C12P7/18 , C12P7/42 , C12P7/44 , C12P13/001 , C12P13/005 , C12P17/10 , C12Y101/01035 , C12Y101/01036 , C12Y101/011 , C12Y101/01157 , C12Y102/99006 , C12Y103/01008 , C12Y103/01038 , C12Y103/01044 , C12Y203/01016 , C12Y203/01174 , C12Y206/01 , C12Y402/01017 , C12Y402/01119
摘要： This document describes biochemical pathways for producing 6-hydroxyhexanoic acid using a polypeptide having
ß-ketothiolase activity to form a 3-oxo-6-hydroxyhexanoyl-CoA intermediate. 6-hydroxyhexanoic acid can be enzymatically converted to adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol. This document also describes recombinant hosts producing 6-hydroxyhexanoic acid as well as adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine and 1,6-hexanediol.
摘要翻译：该文献描述了使用具有β-酮硫解酶活性的多肽生成6-羟基己酸以形成3-氧代-6-羟基己酰基-CoA中间体的生物化学途径。 6-羟基己酸可以酶促转化为己二酸，己内酰胺，6-氨基己酸，六亚甲基二胺或1,6-己二醇。该文件还描述了生产6-羟基己酸以及己二酸，己内酰胺，6-氨基己酸，六亚甲基二胺和1,6-己二醇的重组宿主。

7. 发明公开

EP2924122A1 1,4-BUTANEDIOL MANUFACTURING METHOD AND MICROORGANISM 有权
标题翻译： 1,4-丁二醇方法和微生物
公开(公告)号：EP2924122A1
公开(公告)日：2015-09-30
申请号：EP13856298.8
申请日：2013-09-13
申请人： Showa Denko K.K.
发明人： AOKI, Hirobumi , KOKIDO, Yuzuru , HASHIMOTO, Yoko , YONEDA, Tadashi
IPC分类号： C12P7/18 , C12N1/19 , C12N1/21 , C12N15/09
CPC分类号： C12P7/18 , C12N9/0006 , C12N9/0008 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y101/01035 , C12Y101/01036 , C12Y101/01157 , C12Y102/0101 , C12Y402/01017 , C12Y402/01055 , C12Y402/01119 , C12Y402/0112 , C12Y503/03003
摘要： A method of manufacturing 1,4-butanediol, using a microbe and/or a culture thereof, by an enzyme reaction system that uses acetoacetyl-CoA reductase and enoyl-CoA hydratase, via acetoacetyl-CoA, 3-hydroxybutyryl-CoA and crotonyl-CoA in this order, wherein each of the acetoacetyl-CoA reductase and the enoyl-CoA hydratase is specific to a stereoisomer of 3-hydroxybutyryl-CoA.

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