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1. 发明授权

EP2861731B1 VERFAHREN ZUR AKTIVIERUNG EINER OBERFLÄCHE DURCH ERHÖHUNG DER HYDROPHILIE UND/ODER FÜR DIE ANBINDUNG VON ZIELSTRUKTUREN 有权
标题翻译： VERFAHREN ZUR AKTIVIERUNG EINEROBERFLÄCHEDURCHERHÖHUNGDER HYDROPHILIE UND / ODER FERR DIE ANBINDUNG VON ZIELSTRUKTUREN
公开(公告)号：EP2861731B1
公开(公告)日：2017-08-09
申请号：EP13730524.9
申请日：2013-06-14
申请人： FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V.
发明人： SZARDENINGS, Michael , RISCHKA, Klaus , GRUNWALD, Ingo , EISENSCHMIDT, Annika
IPC分类号： C12N11/00
CPC分类号： C12N11/08 , C08F12/08 , C12N9/0055 , C12N9/0061 , C12N11/00 , C12N2533/00 , C12N2533/50 , C12Y110/03002

2. 发明公开

EP2861731A1 VERFAHREN ZUR AKTIVIERUNG EINER OBERFLÄCHE DURCH ERHÖHUNG DER HYDROPHILIE UND/ODER FÜR DIE ANBINDUNG VON ZIELSTRUKTUREN 有权
标题翻译：方法用于激活的表面通过增加亲水性和/或目标结构的连接
公开(公告)号：EP2861731A1
公开(公告)日：2015-04-22
申请号：EP13730524.9
申请日：2013-06-14
申请人： FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V.
发明人： SZARDENINGS, Michael , RISCHKA, Klaus , GRUNWALD, Ingo , EISENSCHMIDT, Annika
IPC分类号： C12N11/00
CPC分类号： C12N11/08 , C08F12/08 , C12N9/0055 , C12N9/0061 , C12N11/00 , C12N2533/00 , C12N2533/50 , C12Y110/03002
摘要： The invention relates to a method for activating a surface by increasing the hydrophilicity and/or for the bonding of target structures, in particular selected from the group comprising proteins, cell proteins, proteins, cells, carbohydrates, peptides, and amino acids. The invention further relates to the use of an oxidoreductase for activating a surface for said bonds and corresponding activated surfaces.
摘要翻译：本发明涉及用于通过增加亲水性和/或用于结合靶结构，选自蛋白质，细胞蛋白，蛋白质，细胞，碳水化合物，肽和氨基酸的特别选择活化表面的方法。因此，它涉及使用氧化还原酶的活化表面对于所提到的键和对应的活化的表面。

3. 发明公开

EP2049666A2 COMPOSITION AND METHOD FOR TREATMENT OF TUMORS 审中-公开
标题翻译：成分和方法治疗肿瘤
公开(公告)号：EP2049666A2
公开(公告)日：2009-04-22
申请号：EP07813317.0
申请日：2007-07-25
申请人： Sanofi-Aventis
发明人： AUGUST, Paul , HUANG, Waan Jeng , NATESAN, Sridaran , LIEBERMAN, Soyan
IPC分类号： C12N15/11 , A61K39/00 , A61K31/7105 , A61P35/00
CPC分类号： A61K31/7105 , A61K9/0019 , A61K48/00 , C12N9/0055 , C12N15/1136 , C12N15/1137 , C12N2310/14 , C12N2799/027 , C12Y110/02002
摘要： The present invention relates to a composition which is useful in the treatment of a tumor, a method for making such a composition, and a method for using such a composition. The invention relates also to a method for assaying for inhibitors of the activity of Core 1 protein and/or other proteins of the respiratory complex III of mitochondria.

4. 发明授权

EP2375481B1 Biopile à glucose 有权转让
标题翻译：葡萄糖生物堆
公开(公告)号：EP2375481B1
公开(公告)日：2012-08-22
申请号：EP11160991.3
申请日：2011-04-04
申请人： Université Joseph Fourier
发明人： Cinquin, Philippe , Gondran, Chantal , Giroud, Fabien , Cosnier, Serge
IPC分类号： H01M4/90 , H01M8/16 , C12N9/00 , C12N9/02 , C12N9/04
CPC分类号： H01M8/16 , C12N9/0006 , C12N9/001 , C12N9/0055 , C12N9/0071 , H01M4/90 , Y02E60/527

5. 发明公开

EP1846552A2 NOVEL GENE RCS 06 审中-公开
公开(公告)号：EP1846552A2
公开(公告)日：2007-10-24
申请号：EP06706848.6
申请日：2006-02-10
申请人： DSM IP Assets B.V.
发明人： CHEVREUX, Bastien , MAYER, Anne, Françoise , MEURY,Anja , MOUNCEY, Nigel, John , SHINJOH, Masako
IPC分类号： C12N9/02
CPC分类号： C12N9/0055 , C12P7/60
摘要： The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. The present invention also relates to the use of said polynucleotides and polypeptides as biotechnological tools in the production of Vitamin C from microorganisms, whereby a modification of said polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of the fermentation product in said microorganism. Also included are methods/processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms. The invention also relates to genetically engineered microorganisms and their use for the direct production of Vitamin C.
摘要翻译：本发明涉及编码参与L-抗坏血酸合成的蛋白质（以下也称为维生素C）的新鉴定的基因。本发明的特征还在于包含新基因及其片段的全长多核苷酸序列的多核苷酸，由该多核苷酸及其片段编码的新多肽以及它们的功能等价物。本发明还涉及所述多核苷酸和多肽作为生物技术工具在由微生物生产维生素C中的用途，由此修饰所述多核苷酸和/或编码的多肽对产量，产量和/或所述微生物中发酵产物的生产效率。还包括使用多核苷酸和修饰的多核苷酸序列转化宿主微生物的方法/过程。本发明还涉及基因工程微生物及其用于直接生产维生素C的用途。

6. 发明公开

EP2375481A1 Biopile à glucose 有权转让
标题翻译：葡萄糖生物堆
公开(公告)号：EP2375481A1
公开(公告)日：2011-10-12
申请号：EP11160991.3
申请日：2011-04-04
申请人： Université Joseph Fourier
发明人： Cinquin, Philippe , Gondran, Chantal , Giroud, Fabien , Cosnier, Serge
IPC分类号： H01M4/90 , H01M8/16 , C12N9/00
CPC分类号： H01M8/16 , C12N9/0006 , C12N9/001 , C12N9/0055 , C12N9/0071 , H01M4/90 , Y02E60/527
摘要： L'invention concerne une biopile destinée à être immergée dans un milieu liquide contenant un sucre et de l'oxygène, dans laquelle l'anode comprend une enzyme apte à catalyser l'oxydation du sucre et un médiateur redox et la cathode comprend une enzyme apte à catalyser la réduction de l'oxygène et un médiateur redox. Chacune des électrodes d'anode et de cathode est constituée d'un agglomérat solide d'un matériau conducteur mélangé à l'enzyme et au médiateur redox appropriés, est solidaire d'un fil d'électrode et est entourée d'une membrane semi-perméable laissant passer l'oxygène et le glucose et ne laissant pas passer l'enzyme et le médiateur redox.
L'ensemble des deux électrodes est également entouré d'une membrane semi-perméable.
摘要翻译：本发明涉及一种意在被浸渍在含有糖和氧的液体培养基中的生物燃料电池，其中所述阳极包括能够催化糖的氧化和氧化还原介体的酶和所述阴极包括合适的酶以催化氧和氧化还原介体的还原。阳极和阴极电极中的每一个与所述酶和合适的氧化还原介体混合的导电材料的固体团块的形成，被固定到电极线，并且由膜包围半渗透性渗透氧和葡萄糖，不通过酶和氧化还原介体。两组电极也被半透膜包围。

7. 发明公开

EP1181391A2 METHOD OF DETECTION OF CYTOCHROME B MUTATIONS IN FUNGHI LEADING TO RESISTANCE AGAINST ANTI-FUNGAL AGENTS 审中-公开
标题翻译：检测方法的细胞色素b的突变对电阻防菌糠LEAD
公开(公告)号：EP1181391A2
公开(公告)日：2002-02-27
申请号：EP00925493.9
申请日：2000-04-26
申请人： Syngenta Limited
发明人： WINDASS, John, David , HEANEY, Stephen, Paul , RENWICK, Annabel , WHITCOMBE, David, Mark , LITTLE, Stephen , GIBSON, Neil, James , THEAKER, Jane , STANGER, Carole, Patricia
IPC分类号： C12Q1/68 , C07K14/37 , C12N15/53 , G06F19/00 , G06F17/30
CPC分类号： C12N9/0055 , C07K14/80 , C12Q1/6895 , C12Q2600/156 , C12Q2600/16
摘要： The invention discloses methods which are particularly sensitive for detecting low frequencies of mutations in mitochondrially encoded genes, such as the cytochrome b gene, making these an especially useful and commercially important way of screening plant pathogenic fungi for the onset of fungicidal resistance wherein the resistance is due to a mutation in a mitochondrially encoded gene. The methods disclosed include single nucleotide polymorphism detection techniques especially PCR detection methods. Also disclosed are DNA sequences encoding part of the wild type and mutant cytochrome b sequences of a range of plant pathogenic fungi and the use of the sequence information to detect mutations giving rise to fungicidal resistance. Allele specific oligonucleotides and oligonucleotide probes, diagnostic primers and diagnostic kits are also disclosed.

8. 发明公开

EP4421178A2 TRANSGENIC PLANTS WITH INCREASED PHOTOSYNTHESIS EFFICIENCY AND GROWTH 审中-实审
公开(公告)号：EP4421178A2
公开(公告)日：2024-08-28
申请号：EP24184579.1
申请日：2017-05-26
申请人： The Board of Trustees of the University of Illinois , The Regents of the University of California
发明人： LONG, Stephen , KROMDIJK, Johannes , GLOWACKA, Katarzyna , NIYOGI, Krishna, K , LEONELLI, Laurie , GABILLY, Stephane, T.
IPC分类号： C12N15/82
CPC分类号： C12N15/8269 , C12N9/0055 , C12N9/0073 , C12Y110/99003 , C12Y114/1309 , Y02P60/20 , Y02A40/146
摘要： The present disclosure provides a transgenic plant comprising one or more nucleotide sequences encoding polypeptides selected from photosystem II subunit S (PsbS), zeaxanthin epoxidase (ZEP), and violaxanthin de-epoxidase (VDE), operably linked to at least one expression control sequence. Expression vectors for making transgenic plants, and methods for increasing biomass production and/or carbon fixation and/or growth in a plant comprising increasing expression of at least one of PsbS, ZEP and VDE polypeptides are also provided.

9. 发明授权

EP3464601B1 TRANSGENIC PLANTS WITH INCREASED PHOTOSYNTHESIS EFFICIENCY AND GROWTH 有权转让
公开(公告)号：EP3464601B1
公开(公告)日：2024-07-03
申请号：EP17729973.2
申请日：2017-05-26
IPC分类号： C12N15/82
CPC分类号： C12N15/8269 , C12N9/0055 , C12N9/0073 , C12Y110/99003 , C12Y114/1309 , Y02P60/20 , Y02A40/146

10. 发明公开

EP1195433A3 Respiratory chain enzyme genes of coryneform bacteria 审中-公开
标题翻译：从棒状杆菌型呼吸链的酶的基因
公开(公告)号：EP1195433A3
公开(公告)日：2002-06-12
申请号：EP01121110.9
申请日：2001-09-03
申请人： Ajinomoto Co., Inc.
发明人： Sone, Nobuhito
IPC分类号： C12N9/02 , C12N15/53
CPC分类号： C12N9/0053 , C12N9/0055
摘要： A gene coding for aa3 subunit I is obtained from a Corynebacterium glutamicum chromosomal DNA library by hybridization utilizing a probe produced based on a sequence common to a wide range of heme-copper enzymes. A gene coding for subunit II and a gene coding for subunit III are obtained by hybridization using a probe produced by using primers prepared based on the N-terminus amino acid sequence of subunit II, which is determined by using purified cytochrome aa3, and an operon coding for cytochrome bcl complex existing downstream from the foregoing genes is further obtained.

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