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1. 发明公开

EP4441252A1 PSILOCYBE ASSAY 审中-实审
公开(公告)号：EP4441252A1
公开(公告)日：2024-10-09
申请号：EP22843582.2
申请日：2022-12-01
申请人： Medicinal Genomics Corporation
发明人： MCKERNAN, Kevin
IPC分类号： C12Q1/6895 , C12Q1/689 , C12Q1/686
CPC分类号： C12Q1/6895 , C12Q1/689 , C12Q1/686

2. 发明授权

EP3976835B1 A METHOD FOR DETERMINING A YEAST HAVING EXTRACELLULAR GLUCOAMYLASE STA1P ACTIVITY IN A SAMPLE AND TOOLS AND USES RELATED THERETO 有权
公开(公告)号：EP3976835B1
公开(公告)日：2024-07-17
申请号：EP20731522.7
申请日：2020-05-29
IPC分类号： C12Q1/6895
CPC分类号： C12Q1/6895 , C12Q2600/15620130101

3. 发明公开

EP4391796A1 CROWN ROT RESISTANCE 审中-实审
公开(公告)号：EP4391796A1
公开(公告)日：2024-07-03
申请号：EP22859608.6
申请日：2022-08-22
申请人： Commonwealth Scientific and Industrial Research Organisation
发明人： JIANG, Yunfeng , ZHENG, Zhi , AYLIFFE, Michael , GARDINER, Donald , LIU, Chunji , GLASSOP, Donna
IPC分类号： A01H1/00 , A01H1/04 , A01H6/46 , C12N15/82 , C12N9/04 , C12Q1/6895
CPC分类号： C12Q1/6895 , C12N9/0008 , C12Y102/01044 , C12N15/8282 , A01H6/4624 , A01H5/10 , A01H1/1255 , C12Q2600/1320130101

4. 发明授权

EP2515630B1 GENETIC MARKERS ASSOCIATED WITH DROUGHT TOLERANCE IN MAIZE 有权转让
公开(公告)号：EP2515630B1
公开(公告)日：2024-06-05
申请号：EP10840172.0
申请日：2010-12-23
IPC分类号： A01H5/10 , C12Q1/6895 , A01H1/00 , A01H1/04 , A01H6/46
CPC分类号： C12Q2600/1320130101 , C12Q2600/15620130101 , C12Q2600/17220130101 , Y02A40/132 , A01H5/10 , C12Q1/6895 , A01H1/00 , A01H6/4684 , A01H1/045

5. 发明授权

EP3850106B1 METHODS OF IDENTIFYING DHA CANOLA NS-B50027-4 有权转让
公开(公告)号：EP3850106B1
公开(公告)日：2024-05-29
申请号：EP19858886.5
申请日：2019-09-09
IPC分类号： C12Q1/68 , C12Q1/6806 , C12Q1/6844 , C12Q1/6848 , C12Q1/6851 , C12Q1/6853
CPC分类号： C12Q1/6851 , C12Q1/6853 , C12Q1/6848 , C12Q1/6895 , C12Q2600/1320130101 , C12Q2600/1620130101 , C12Q1/686 , C12Q2600/15820130101

6. 发明公开

EP4366513A1 NOVEL MARKERS COMBINATION IN SWEET BASIL FOR DISEASE RESISTANCES 审中-实审
公开(公告)号：EP4366513A1
公开(公告)日：2024-05-15
申请号：EP23828678.5
申请日：2023-01-19
申请人： Bar Ilan University
发明人： COHEN, Yigal , BEN NAIM, Yariv
IPC分类号： A01H5/10 , A01H6/50 , C12Q1/6895
CPC分类号： C12Q1/6895 , A01H5/12 , A01H6/506 , A01H1/1255 , C12Q2600/15620130101

7. 发明授权

EP3063294B1 PREDICTION OF HYBRID TRAITS 有权
公开(公告)号：EP3063294B1
公开(公告)日：2018-12-05
申请号：EP14793824.5
申请日：2014-10-27
申请人： Hi Fidelity Genetics LLC
发明人： SCHOLTEN, Stefan , THIEMANN, Alexander , SEIFERT, Felix , FRISCH, Matthias , MELCHINGER, Albrecht
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6895 , C12Q2600/13 , C12Q2600/158 , C12Q2600/178
摘要： A method for the prediction of hybrid traits in plants and animals, wherein sRNA molecules which are associated with a hybrid trait are identified and parent lines which are suitable for the production of hybrids are analyzed for the level of an expression of the identified sRNA molecules. The invention allows the selection of suitable organisms for the production of plant and animal hybrids having an increased hybrid vigor respectively heterosis for one or more hybrid traits, such as yield, fertility, stress resistance, etc.

8. 发明授权

EP2660335B1 Highly conserved genes and their use to generate species-specific, genus-specific, family-specific, group-specific and universal nucleic acid probes and amplification primers to rapidly detect and identify algal, archaeal, bacterial, fungal and parasitical microorgamisms from clinical specimens for diagnosis 有权
公开(公告)号：EP2660335B1
公开(公告)日：2018-11-21
申请号：EP13167883.1
申请日：2000-09-28
申请人： Geneohm Sciences Canada, Inc.
发明人： Bergeron, Michel G. , Boissinot, Maurice , Huletsky, Ann , Ménard, Christian , Ouellette, Marc , Picard, François J. , Roy, Paul H.
IPC分类号： C12Q1/68 , C07K14/00 , C12N15/63 , C12N5/10
CPC分类号： C12Q1/6895 , C12Q1/689 , C12Q1/6893 , C12Q2600/156 , C12Q2600/16 , Y02A50/55
摘要： The highly conserved gene encoding the catalytic subunit of proton-translocating ATPase is used to generate a sequence repertory or bank and species-specific, genus-specific, family-specific, group-specific and universal nucleic acid probes and amplification primers to rapidly detect and identify algal, archaeal, bacterial, fungal and parasitical microorganisms from specimens for diagnosis. The detection of associated antimicrobial agents resistance and toxin genes are also under the scope of the present invention.

9. 发明授权

EP2938727B1 GENES/GENETIC ELEMENTS ASSOCIATED WITH MATING IMPAIRMENT IN TRICHODERMA REESEI QM6A AND ITS DERIVATIVES AND PROCESS FOR THEIR IDENTIFICATION 有权
公开(公告)号：EP2938727B1
公开(公告)日：2018-11-14
申请号：EP13814970.3
申请日：2013-12-23
申请人： AB Enzymes GmbH
发明人： KUBICEK, Christian, P. , LINKE, Rita , SEIBOTH, Bernhard , HAARMANN, Thomas , LORENZ, Patrick
IPC分类号： C12N15/80 , C07K14/37 , C12R1/885 , C12N1/14
CPC分类号： C12Q1/6895 , C07K14/37 , C12N1/14 , C12N15/80 , C12Q2600/156 , C12R1/885
摘要： The invention relates to a process for identifying gene(s)/genetic element(s) associated with mating impairment in strains of Trichoderma reesei QM6a or strains derived thereof comprising the steps of a) providing a first strain being a Trichoderma reesei QM6a strain having a MAT1-2 locus or a strain derived thereof, b) sexually crossing said strain with a second strain being a mating competent strain of a Trichoderma reesei (Hypocrea jecorina) strain having a complementary locus, i.e. the MAT1-1 locus, c) repeatedly back-crossing the MAT1-1 progenies from the crossing of b) or the back-crossing thereof with the first strain of a), until a strain is obtained that is substantially identical to the first Trichoderma reesei QM6a strain or a strain derived thereof, but carries the MAT1-1 locus and is mating competent for crossing with Trichoderma reesei QM6a or any of its MAT1-2 progeny, d) selecting the progeny from step c) that is mating competent for crossing with a Trichoderma reesei (Hypocrea jecorina) having a MAT1-2 locus, and e) identifying the gene(s)/genetic element(s) associated with mating impairment by comparing the genome of the progenies selected in step d) with the genome sequences of the first strain of a) whereby said gene(s)/genetic element(s) may be fully or partially missing or existing in a mutated form or in a form having deletions or insertions in the first strain thus being a gene or a genetic element directly or indirectly associated with mating impairment in strains of Trichoderma reesei QM6a or a strain derived thereof as well as to a process for correcting the mating impairment of a Trichoderma reesei QM6a strain or a strain derived thereof having a MAT1-1 locus and that is not competent to mate with a Trichoderma reesei QM6a strain having a MAT1-2 locus or a strain derived thereof, wherein one or more mutated or fully or partially missing gene(s) and/or genetic element(s) identified as above is/are replaced by or complemented with the corresponding functional gene(s) and/or genetic element(s). Moreover, the invention relates to the use of a thus obtained fungal strain of the genus Trichoderma in industrial breeding and production of a product of interest. Moreover, the invention relates to the genes associated with mating impairment of Trichoderma reesei QM6a and strains derived therefrom and to genes essential for mating of Trichoderma reesei QM6a and strains derived therefrom.

10. 发明公开

EP3395948A1 THREONINE SYNTHASE FROM NICOTIANA TABACUM AND METHODS AND USES THEREOF 审中-公开
公开(公告)号：EP3395948A1
公开(公告)日：2018-10-31
申请号：EP18177740.0
申请日：2012-08-31
申请人： Philip Morris Products S.A.
发明人： BOVET, Lucien , SIERRO, Nicolas
IPC分类号： C12N15/82 , C12N9/88 , A01H5/00
CPC分类号： C12N9/88 , A24B13/00 , C07C381/00 , C12N15/8253 , C12Q1/6895 , C12Q2600/13 , C12Q2600/16 , C12Y402/03001
摘要： A method for increasing the concentration of free methionine in at least a part of a tobacco plant, comprising the steps of:
(a) reducing the expression or activity of threonine synthase in the tobacco plant, wherein the threonine synthase comprises
(i) a polynucleotide comprising or consisting of a sequence encoding a threonine synthase and having at least 90% sequence identity to SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, or SEQ ID NO:5;
(ii) a polypeptide encoded by any one of said polynucleotides set forth in (i); or
(iii) a polypeptide having at least 95% sequence identity to SEQ ID NO:6, SEQ ID NO:7 or SEQ ID NO:8;

(b) measuring the concentration of free methionine in at least a part of the mutant or non-naturally occurring plant obtained in step (i); and
(c) identifying a mutant or non-naturally occurring tobacco plant in which the concentration of free methionine therein has increased by at least 50% in comparison to a control tobacco plant in which the expression or activity of threonine synthase has not been reduced and wherein the visual appearance of said mutant or non-naturally occurring tobacco plant is substantially the same as the control tobacco plant three months after field transplant or 36 days after topping.

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