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1. 发明公开

EP1911751A1 AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND 审中-公开
标题翻译： AMIDDERIVAT UND PESTIZID，DAS EINE SOLCHE VERBINDUNGENTHÄLT
公开(公告)号：EP1911751A1
公开(公告)日：2008-04-16
申请号：EP06766942.4
申请日：2006-06-20
申请人： Mitsui Chemicals, Inc.
发明人： KAI, Akiyoshi , WAKITA, Takeo , KATSUTA, Hiroyuki , YOSHIDA, Kei , TSUKADA, Hidetaka , TAKAHASHI, Yusuke , KAWAHARA, Nobuyuki Mitsui Chemicals Crop Life, Inc , NOMURA, Michikazu , DAIDO, Hidenori
IPC分类号： C07D277/62
CPC分类号： C07C237/42 , A01N37/46 , A01N41/04 , A01N41/10 , A01N43/10 , A01N43/32 , A01N43/36 , A01N43/40 , A01N43/42 , A01N43/56 , A01N43/76 , A01N43/78 , C07C255/57 , C07C309/65 , C07C309/73 , C07C311/08 , C07C311/09 , C07C311/11 , C07C311/21 , C07C317/40 , C07C323/42 , C07C2602/08 , C07C2602/42 , C07C2603/18 , C07C2603/74 , C07D213/75 , C07D213/82 , C07D215/38 , C07D277/62
摘要： The present invention is to provide a compound represented by the general formula (1) exhibiting a high insecticidal effect and an insecticide comprising the compound as an active ingredient. The compound represented by the general formula (1) and an insecticide comprising the compound as an active ingredient,

wherein, in the formula, A 1 , A 2 , A 3 and A 4 each represent a carbon atom or the like; R 1 and R 2 each represent a hydrogen atom or the like; G 1 and G 2 represent an oxygen atom or the like; Xs each represent a hydrogen atom, a halogen atom or the like; n represents an integer of 0 to 4; Q 1 represents a substituted phenyl group, a substituted heterocyclic group or the like; Q 2 represents a substituted phenyl group, a substituted heterocyclic group or the like.
摘要翻译：本发明提供由具有高杀虫作用的通式（1）表示的化合物和包含该化合物作为活性成分的杀虫剂。由通式（1）表示的化合物和包含该化合物作为活性成分的杀虫剂，其中，在式中，A 1，A 2，A 3和A 4各自表示碳原子等; R 1和R 2各自表示氢原子等; G 1和G 2表示氧原子等; X各自表示氢原子，卤素原子等; n表示0〜4的整数， Q 1表示取代的苯基，取代的杂环基等; Q 2表示取代的苯基，取代的杂环基等。

2. 发明公开

EP0608847A1 Carbocyclic sulfonamides as agonists or antagonists of PGEZ 失效
标题翻译： Carbocyclische磺酰胺als Agoniste oder Antagoniste von PGEZ。
公开(公告)号：EP0608847A1
公开(公告)日：1994-08-03
申请号：EP94101085.2
申请日：1994-01-25
申请人： ONO PHARMACEUTICAL CO., LTD.
发明人： Hamanaka, Nobuyuki, c/o Minase Res. Inst. , Miyamoto, Tsumoru
IPC分类号： C07C311/13 , C07C311/20 , C07C311/07 , C07C311/12 , C07C311/27 , C07C311/29 , C07C311/10 , C07C311/11 , A61K31/18
CPC分类号： C07C311/19 , C07C311/07 , C07C311/10 , C07C311/11 , C07C311/13 , C07C311/14 , C07C311/20 , C07C311/27 , C07C311/29
摘要： (1) Prostaglandin (PG) E₂ antagonist or agonist containing carbocyclic sulfonamides represented by the compound of the formula (I):

cyclodextrin clathrates thereof, non-toxic salts thereof as active ingredient,
(2) carbocyclic sulfonamides represented by the compound of the formula (II):

cyclodextrin clathrates thereof, non-toxic salts thereof,
(3) process for the preparation of the compound represented by the compound of the formula (II) described hereinbefore,
(4) PGE₂ antagonist or agonist containing the compound represented by the compound of the formula (II) as active ingredient.
The compounds represented by the compounds of the formula (I) and (II) can be adapted to medicines which possess an inhibitory effect of uterine contraction, an analgetic action, an inhibitory effect of digestive peristalsis, a sleep-inducing effect as PGE₂ antagonists, and an uterine contractile activity, a promaoting effect of digestive peristalsis, a suppressive effect of gastric acid secretion, a hypotensive activity as PGE₂ agonists, because they bind onto PGE₂ receptor and have an activity of antagonist or agonist against the action thereof.
摘要翻译：（1）由式（I）化合物表示的前列腺素（PG）E2拮抗剂或含有碳环磺酰胺的激动剂：其作为活性成分的无毒性盐，（2）化合物所表示的碳环磺酰胺式（II）的化合物：其环糊精包合物，其无毒盐，（3）由上述式（II）化合物表示的化合物的制备方法，（4）PGE2拮抗剂或激动剂含有由式（II）化合物表示的化合物作为活性成分。由式（I）和（II）化合物表示的化合物可以适用于具有子宫收缩抑制作用，止痛作用，消化性蠕动抑制作用，睡眠诱导作用PGE2拮抗剂的药物，因为它们结合PGE2受体并且具有针对其作用的拮抗剂或激动剂的活性，因此其作为PGE2激动剂的降血压活性，以及子宫收缩活动，消化道蠕动的促进作用，胃酸分泌的抑制作用。

3. 发明授权

EP0357953B1 Mischungen von organischen Ammonium-Salzen und deren Verwendung als Strömungsbeschleuniger 失效
标题翻译：有机铵盐的混合物及其作为还原剂的用途
公开(公告)号：EP0357953B1
公开(公告)日：1993-04-07
申请号：EP89114244.0
申请日：1989-08-02
申请人： HOECHST AKTIENGESELLSCHAFT
发明人： Ohlendorf, Dieter, Dr. , Hofinger, Manfred, Dr. , Wehle, Detlef, Dr.
IPC分类号： C07C211/63 , F15D1/00
CPC分类号： C07C311/03 , C07C39/14 , C07C211/63 , C07C215/90 , C07C311/11 , C09K3/00 , Y10S516/05 , Y10S516/06 , Y10S516/07

4. 发明授权

EP0947500B1 SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT 失效
标题翻译：磺酰胺衍生物并将此作为有效成分含药物
公开(公告)号：EP0947500B1
公开(公告)日：2011-02-23
申请号：EP97947925.0
申请日：1997-12-12
申请人： ONO PHARMACEUTICAL CO., LTD.
发明人： OHUCHIDA, Shuichi, Minase Res Ins ONO Pharm Co ltd , NAGAO, Yuuki, Minase Res. Inst. ONO Pharm. Co. Ltd
IPC分类号： C07C233/25 , C07C233/75 , C07C237/42 , C07C311/13 , C07C311/21 , C07C311/17 , C07C311/29 , C07D213/76 , C07D213/80 , C07D307/42 , C07D307/64 , C07D307/68 , C07D333/34 , C07D333/40 , A61K31/195 , A61K31/24 , A61K31/245 , A61K31/34 , A61K31/38
CPC分类号： C07D213/80 , C07C233/18 , C07C233/75 , C07C311/08 , C07C311/10 , C07C311/11 , C07C311/13 , C07C311/14 , C07C311/17 , C07C311/21 , C07C311/29 , C07C313/06 , C07C323/67 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07D307/64 , C07D307/68 , C07D333/34 , C07D333/38
摘要： Sulfonamide and carboxamide derivatives represented by general formula (I) wherein the rings A and B represent each a carbocycle or a heterocycle; Z1 represents -COR1, -CH=CH-COR1, etc.; Z2 represents H, alkyl, etc.; Z3 represents a single bond or alkylene; Z4 represents SO¿2? or CO; Z?5¿ represents alkyl, phenyl, a heterocycle, etc., R2 represents CONR8, O, S, NZ6, Z7-alkylene, alkylene, etc.; R3 represents H, alkyl, halogeno, CF¿3?, etc.; R?4¿ represents H, optionally substituted alkyl, etc., and n and t are each from 1 to 4. The compounds of general formula (I) bind to PGE¿2? receptors and exert an antagonism or agonism thereto. Thus, they are applicable to drugs having the effects of inhibiting uterine muscle contraction, analgesia, inhibiting digestive tract movement, hypnosis, enlarging vesical capacity, contracting the uterine, promoting the digestive tract movement, suppressing the secretion of gastric hydrochloric acid, lowering blood pressure, or diuresis.

5. 发明公开

EP1379493A2 NON-IMIDAZOLE ARYL ALKYLAMINES COMPOUNDS AS HISTAMINE H3 RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES 审中-公开
标题翻译：非咪唑阿魏酸亚苄基维生素ALS组胺素H3抗抑郁药，HERSTELLUNG UND PHARMAZEUTISCHE VERWENDUNGEN
公开(公告)号：EP1379493A2
公开(公告)日：2004-01-14
申请号：EP02723329.5
申请日：2002-03-21
申请人： Eli Lilly and Company
发明人： BEAVERS, Lisa, Selsam , GADSKI, Robert, Alan , HIPSKIND, Philip, Arthur , LINDSLEY, Craig, William , LOBB, Karen, Lynn , NIXON, James, Arthur , PICKARD, Richard, Todd , SCHAUS, John, Mehnert , TAKAKUWA, Takako , WATSON, Brian, Morgan
IPC分类号： C07C217/58 , A61K31/395 , A61K31/131 , A61P3/00 , A61P25/00 , C07D295/08 , C07D295/12 , C07C217/20 , C07C311/05 , C07C311/13 , C07C311/18 , C07C237/08 , C07D295/14 , C07C217/74 , C07C271/34 , C07C323/62 , C07C271/24 , C07C233/73 , C07C237/32 , C07C311/17 , C07C409/12
CPC分类号： C07D207/27 , C07B2200/07 , C07C217/20 , C07C217/58 , C07C217/74 , C07C233/73 , C07C237/08 , C07C237/32 , C07C271/24 , C07C271/34 , C07C311/05 , C07C311/09 , C07C311/11 , C07C311/18 , C07C2601/02 , C07C2601/14 , C07C2602/10 , C07D207/09 , C07D207/14 , C07D207/16 , C07D211/22 , C07D211/26 , C07D213/38 , C07D215/20 , C07D217/06 , C07D217/08 , C07D217/24 , C07D231/04 , C07D231/12 , C07D233/36 , C07D233/56 , C07D235/14 , C07D241/44 , C07D243/08 , C07D249/08 , C07D295/088 , C07D295/096 , C07D295/13 , C07D295/15 , C07D307/12 , C07D307/14 , C07D307/46 , C07D333/34 , C07D401/06 , C07D409/06 , C07D409/12 , C07D413/06 , C07D417/06 , C07D487/04
摘要： The present invention discloses novel substituted aryl alkylamine compounds of Formula (I) or pharmaceutically acceptable salts thereofwhich have selective histamine-H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such cyclic amines as well as methods of using them to treat obesity and other histamine H3 receptor -related diseases.
摘要翻译：本发明公开了具有选择性组胺-H 3受体拮抗剂活性的式（I）的新型取代芳基烷基胺化合物或其药学上可接受的盐以及其制备方法。在另一个实施方案中，本发明公开了包含这种环胺的药物组合物以及使用它们治疗肥胖症和其他组胺H3受体相关疾病的方法。

6. 发明公开

EP0947500A1 SULFONAMIDE AND CARBOXAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT 失效
标题翻译： SULFONAMID-DERIVATE UND DIESE ALS AKTIVE BESTANDTEILE ENTHALTENDE MEDIKAMENTE
公开(公告)号：EP0947500A1
公开(公告)日：1999-10-06
申请号：EP97947925.0
申请日：1997-12-12
申请人： ONO PHARMACEUTICAL CO., LTD.
发明人： OHUCHIDA, Shuichi, Minase Res Ins ONO Pharm Co ltd , NAGAO, Yuuki, Minase Res. Inst. ONO Pharm. Co. Ltd
IPC分类号： C07C233/25 , C07C233/75 , C07C237/42 , C07C311/13 , C07C311/21 , C07C311/17 , C07C311/29 , C07D213/76 , C07D213/80 , C07D307/42 , C07D307/64 , C07D307/68 , C07D333/34 , C07D333/40 , A61K31/195 , A61K31/24 , A61K31/245 , A61K31/34 , A61K31/38
CPC分类号： C07D213/80 , C07C233/18 , C07C233/75 , C07C311/08 , C07C311/10 , C07C311/11 , C07C311/13 , C07C311/14 , C07C311/17 , C07C311/21 , C07C311/29 , C07C313/06 , C07C323/67 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07D307/64 , C07D307/68 , C07D333/34 , C07D333/38
摘要： The sulfonamide or carboamide derivatives of the formula (I) and a pharmaceutical composition which comprise them as an active ingredient:
(wherein A ring, B ring is carbocyclic ring, heterocyclic ring; Z 1 is -COR 1 , -CH=CH-COR 1 etc.; Z 2 is H, alkyl etc.; Z 3 is single bond, alkylene; Z 4 is SO 2 , CO; Z 5 is alkyl, phenyl, heterocyclic ring etc.; R 2 is CONR 8 , O, S, NZ 6 , Z 7 -alkylene, alkylene etc.; R 3 is H, alkyl, halogen, CF 3 etc.; R 4 is H, (substituted) alkyl etc.; n, t is 1-4).
The compounds of the formula (I) can bind to receptors of PGE 2 and show antagonistic activity against the action thereof or agonistic activity. Therefore, they are considered to be useful as medicine for inhibition of uterine contraction, analgesics, antidiarrheals, sleep inducers, medicine for increase of vesical capacity or medicine for uterine contraction, cathartic, suppression of gastric acid secretion, antihypertensive or diuretic agents.
摘要翻译：式（I）的磺酰胺或氨基酰胺衍生物和包含它们作为活性成分的药物组合物：其中A环，B环为碳环，杂环; Z 1为-COR 1 ，-CH = CH-COR 1等; Z 2是H，烷基等; Z 3是单键，亚烷基; Z 4是SO 2，CO; Z 5是烷基，苯基，杂环等; R 2是CONR 8，O，S，NZ 6，Z 7 - 亚烷基，亚烷基等; R 3是H，烷基，卤素，CF 3等 R 4是H，（取代的）烷基等; n，t是1-4）。式（I）的化合物可以与PGE2的受体结合，并且显示出对其作用或激动活性的拮抗活性。因此，它们被认为可用作抑制子宫收缩，止痛剂，止泻药，睡眠诱导剂，用于增加膀胱容量的药物或药物用于子宫收缩，通气，抑制胃酸分泌，抗高血压或利尿剂的药物。

7. 发明公开

EP0810209A3 Alpha - and beta-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors 有权转让
标题翻译：羟乙基氨基磺酰胺verwendbar als Inhibitoren逆转录病毒蛋白酶
公开(公告)号：EP0810209A3
公开(公告)日：1998-12-02
申请号：EP97113434
申请日：1993-08-24
申请人： SEARLE & CO , MONSANTO CO
发明人： VAZQUEZ MICHAEL L , MUELLER RICHARD A , TALLEY JOHN J , GETMAN DANIEL , DECRESCENZO GARY A , FRESKOS JOHN N
IPC分类号： C07D295/12 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4418 , A61K31/4433 , A61K31/505 , A61K31/535 , A61K31/5375 , A61K38/00 , A61P31/12 , C07C311/05 , C07C311/11 , C07C311/13 , C07C311/14 , C07C311/18 , C07C311/20 , C07C311/24 , C07C311/29 , C07C311/32 , C07C311/41 , C07C311/46 , C07C313/06 , C07C317/04 , C07C317/10 , C07C317/14 , C07C317/28 , C07C317/44 , C07C323/49 , C07C323/57 , C07C323/67 , C07C327/38 , C07D209/08 , C07D211/78 , C07D213/30 , C07D213/53 , C07D213/56 , C07D213/64 , C07D213/73 , C07D213/81 , C07D213/82 , C07D213/89 , C07D215/48 , C07D233/54 , C07D239/02 , C07D239/26 , C07D277/24 , C07D277/30 , C07D277/82 , C07D307/20 , C07D307/42 , C07D307/79 , C07D317/62 , C07D333/34 , C07D405/12 , C07D409/12 , C07D417/12 , C07K5/06 , C07K5/078
CPC分类号： C07C311/05 , A61K38/00 , C07C311/11 , C07C311/13 , C07C311/14 , C07C311/18 , C07C311/20 , C07C311/24 , C07C311/29 , C07C311/32 , C07C311/41 , C07C311/46 , C07C317/04 , C07C317/10 , C07C317/14 , C07C317/28 , C07C317/44 , C07C323/49 , C07C323/67 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/10 , C07D209/08 , C07D213/30 , C07D213/64 , C07D213/73 , C07D213/81 , C07D213/82 , C07D213/89 , C07D215/48 , C07D233/64 , C07D239/26 , C07D277/24 , C07D277/82 , C07D307/20 , C07D307/42 , C07D307/79 , C07D317/62 , C07D333/34 , C07D405/12 , C07D417/12 , C07K5/06026 , C07K5/06139
摘要： The present invention provides retroviral protease inhibitor compounds represented by the Formula I:
Such compounds are urseful for preparing medicaments for inhibiting proteases, especially for inhibiting HIV protease and for treating a retroviral infection such as HIV infection and for treating AIDS.
摘要翻译：本发明提供由式I表示的逆转录病毒蛋白酶抑制剂化合物：此类化合物适用于制备用于抑制蛋白酶的药物，特别是用于抑制HIV蛋白酶和用于治疗逆转录病毒感染如HIV感染和用于治疗AIDS。

8. 发明公开

EP0357953A1 Mischungen von organischen Ammonium-Salzen und deren Verwendung als Strömungsbeschleuniger 失效
标题翻译：的有机铵盐的混合物以及它们作为流动加速剂的用途。
公开(公告)号：EP0357953A1
公开(公告)日：1990-03-14
申请号：EP89114244.0
申请日：1989-08-02
申请人： HOECHST AKTIENGESELLSCHAFT
发明人： Ohlendorf, Dieter, Dr. , Hofinger, Manfred, Dr. , Wehle, Detlef, Dr.
IPC分类号： C07C211/63 , F15D1/00
CPC分类号： C07C311/03 , C07C39/14 , C07C211/63 , C07C215/90 , C07C311/11 , C09K3/00 , Y10S516/05 , Y10S516/06 , Y10S516/07
摘要： Mischungen von organischen Ammoniumsalzen bestehend aus 20 bis 80 Gew.-% eines quaternären Ammoniumsalzes der Formel
ß-Hydroxynaphthoat (-)
und
80 bis 20 Gew.-% eines Aminsalzes der Formel
ß-Hydroxynaphthoat (-)
wobei in beiden Formel R¹ C₁₂-C₂₆-Alkyl, C₁₂-C₂₆-Alkenyl, C₁₂-C₂₆-Fluoralkyl, C₁₂-C₂₆-Fluoralkenyl oder eine Gruppe der Formeln
oder R f -(CH₂) y B(CH₂) x -
R² und R³ C₁-C₃-Alkyl, vorzugsweise Methyl,
R⁴ C₁-C₄-Alkyl und für den Fall R¹ = Alkyl oder Alkenyl auch eine Gruppe der Formel -(C₂H₄O) z H
R f C₈-C₂₀-Fluoralkyl oder C₈-C₂₀-Fluoralkenyl,
R⁵ Wasserstoff, Methyl oder Ethyl,
B Sauerstoff oder Schwefel,
x eine ganze Zahl von 2 bis 6,
y 0, 1 oder 2
und z Zahlen von 1 bis 4 bedeuten und zusätzlich 30 - 70 Mol-%,
vorzugsweise 40 - 60 Mol-%, besonders bevorzugt 50 Mol-% Alkali-Salicylat berechnet auf die Gesamtmenge an ß-Hydroxynaphthoesäure.
摘要翻译： 20组成的有机铵盐的混合物至80重量式β-羟基萘<（ - ）>的季铵盐的％和80至20重量的式β-羟基萘<的胺盐的％（ - ）>其中，在通式两个R C12-C26烷基，C12-C26链烯基，C12-C26氟烷基，C12-C26-氟代或下式基团的或R f - （CH 2）Y B（CH 2）x R 2和R 3的C1-C3烷基，优选甲基，R <4> C1-C4烷基，和=的情况下R'是烷基或烯基，也一式的基团 - （C2H4O）z的RF C8-C20-氟烷基或C8-C20 氟代，R <5>是氢，甲基或乙基，B是氧或硫，x是从2至6的整数，y是0，1或2，z是从1至4个，另外30个号码 - 70摩尔％，优选40 - 60％（摩尔），特别优选为50摩尔％对β羟基萘甲酸的总量计算碱金属水杨酸盐。

9. 发明公开

EP2010482A1 COUPLING COMPOUNDS AND HAIR DYEING COMPOSITIONS CONTAINING THEM 审中-公开
标题翻译：偶联化合物和包含它们的头发染色组合物
公开(公告)号：EP2010482A1
公开(公告)日：2009-01-07
申请号：EP07727938.8
申请日：2007-04-10
申请人： DyStar Textilfarben GmbH & Co. Deutschland KG , Kao Corporation
发明人： KÜHLWEIN, Jürgen , RUSS, Werner , PRATT, Dominic , MÖHRING, Hartmut
IPC分类号： C07C311/08 , C07C311/11 , C07C307/10 , C07C311/32 , C07F9/24 , A61K8/46 , A61K8/55
CPC分类号： A61K8/418 , A61K8/411 , A61K8/466 , A61K8/55 , A61Q5/10 , C07C307/10 , C07C311/08 , C07C311/11 , C07C311/32 , C07F9/247
摘要： The present invention refers to compounds of the formula (I) wherein R1, R2, R3 and R4 are defined as given in claim 1, as well as hair dye compositions containing them.
摘要翻译：本发明涉及其中R 1，R 2，R 3和R 4如权利要求1中所定义的式（I）化合物，以及含有它们的染发剂组合物。

10. 发明公开

EP1847528A1 Coupling compounds and hair dyeing compositions containing them 审中-公开
标题翻译： Kuppelnde Verbindungen und diese enthaltendeHaarfärbemittel
公开(公告)号：EP1847528A1
公开(公告)日：2007-10-24
申请号：EP06009090.9
申请日：2006-04-18
申请人： DyStar Textilfarben GmbH & Co. Deutschland KG , Kao Corporation
发明人： Kühlwein, Jürgen , Russ, Werner , Pratt, Dominic , Möhring, Hartmut
IPC分类号： C07C311/08 , C07C311/11 , C07C307/10 , C07C311/32 , C07F9/24 , A61K8/46 , A61K8/55
CPC分类号： A61K8/418 , A61K8/411 , A61K8/466 , A61K8/55 , A61Q5/10 , C07C307/10 , C07C311/08 , C07C311/11 , C07C311/32 , C07F9/247
摘要： The present invention refers to compounds of the formula (I)

wherein
R 1
is (C 1 -C 4 )-alkyl, (C 1 -C 4 )-alkyl which is substituted by hydroxy, (C 1 -C 4 )-alkoxy, hydroxy-(C 1 -C 4 )-alkoxy, CN, -COOR 5 , -CON(R 5 ) 2 or -N(R 5 ) 2 or is phenyl;
R 2
is hydrogen, methyl or ethyl;
R 3
is (C 1 -C 4 )-alkylsulfonyl, (C 1 -C 4 )-alkylsulfonyl which is substituted by hydroxy, halogen, cyano, (C 1 -C 4 )-alkoxy or -N(R 5 ) 2 or is -SO 2 -CH=CH 2 , -SO 2 N(R 5 ) 2 or -PO(OR 5 ) 2 ;
R 4
is hydrogen, (C 2 -C 4 )-alkyl which is substituted by hydroxy, (C 1 -C 4 )-alkoxy or hydroxy-(C 1 -C 4 )-alkoxy;
each of R 5 , independently is hydrogen, (C 1 -C 4 )-alkyl or hydroxy-(C 2 -C 4 )-alkyl; whereas R 3 is not -NHSO 2 CH 3 if R 2 and R 4 are both hydrogen and R 1 is methyl, as well as hair dye compostions containing them.
摘要翻译：本发明涉及式（I）的化合物，其中R 1是（C 1 -C 4） - 烷基，被羟基取代的（C 1 -C 4） - 烷基，（C 1 -C 4） - 烷氧基，羟基 - （C 1 -C 4） - 烷氧基，CN，-COOR 5，-CON（R 5）2或-N（R 5）2或是苯基; R 2是氢，甲基或乙基; R 3是被羟基，卤素，氰基，（C 1 -C 4） - 烷氧基或-N（R 5）2取代的（C 1 -C 4） - 烷基磺酰基，（C 1 -C 4） - 烷基磺酰基或是-SO 2 -CH = CH 2，-SO 2 N（R 5）2或-PO（OR 5）2; R 4是氢，被羟基，（C 1 -C 4） - 烷氧基或羟基 - （C 1 -C 4） - 烷氧基取代的（C 2 -C 4） - 烷基; 每个R 5独立地是氢，（C 1 -C 4） - 烷基或羟基 - （C 2 -C 4） - 烷基; 而如果R 2和R 4均为氢且R 1为甲基，则R 3不为-NHSO 2 CH 3，以及含有它们的染发剂组合物。

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