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1. 发明授权

EP2852433B1 SELF-TEST FOR ANALGESIC PRODUCT 有权
标题翻译：自我测试的镇痛产品
公开(公告)号：EP2852433B1
公开(公告)日：2018-02-21
申请号：EP13794754.5
申请日：2013-03-05
申请人： Incline Therapeutics, Inc. , Alza Corporation
发明人： WHITE, Bradley, E. , LEMKE, John , HAYTER, Paul , CHEN, Corinna, X. , READ, Brian, W. , DOUGHERTY, Jason, E.
IPC分类号： A61N1/30 , A61M37/00 , A61N1/32 , A61N1/04 , G01R19/145 , G01R19/165 , G08B21/18
CPC分类号： G01R19/145 , A61N1/025 , A61N1/0416 , A61N1/0432 , A61N1/08 , A61N1/18 , A61N1/303 , A61N1/325 , A61N1/327 , G01R19/165 , G08B21/182
摘要： Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur.

2. 发明公开

EP3272391A1 IMPLANTABLE MEDICAL DEVICE SYSTEM 审中-实审
标题翻译：可植入医疗设备系统
公开(公告)号：EP3272391A1
公开(公告)日：2018-01-24
申请号：EP17181652.3
申请日：2017-07-17
申请人： BIOTRONIK SE & Co. KG
发明人： Hess, James W.
IPC分类号： A61N1/08 , A61N1/372 , A61N1/37 , A61N1/05
CPC分类号： A61B5/0031 , A61B5/02 , A61N1/056 , A61N1/086 , A61N1/18 , A61N1/37 , A61N1/3718 , A61N1/37229
摘要： The invention relates to an implantable medical device system comprising an active medical device having or connected to at least one electrode and circuitry connected to the electrode. The active medical device comprises a telemetry unit. The circuitry connected to the electrode comprises at least one single conductor that provides a radio frequency antenna for the telemetry unit. The implantable medical device system further comprises at least one electronic filter that is arranged between the single conductor of circuitry connected to the electrode and the telemetry unit. The least one electronic filter comprises at least one inductor having a core that comprises a ferromagnetic material with saturating behavior when exposed to an external magnetic field.
摘要翻译：本发明涉及一种可植入医疗设备系统，其包括具有或连接到至少一个电极的活性医疗设备以及连接到电极的电路。有源医疗设备包括遥测单元。连接到电极的电路包括至少一个为遥测单元提供射频天线的单导体。植入式医疗设备系统还包括至少一个电子滤波器，其布置在连接到电极的电路的单导体和遥测单元之间。至少一个电子滤波器包括至少一个电感器，该电感器具有包含铁磁材料的芯，当暴露于外部磁场时具有饱和行为。

3. 发明授权

EP2561904B1 Apparatus for renal neuromodulation 失效
标题翻译：一种用于肾欧元调制装置
公开(公告)号：EP2561904B1
公开(公告)日：2016-02-10
申请号：EP12180430.6
申请日：2005-10-05
申请人： Medtronic Ardian Luxembourg S.à.r.l.
发明人： Deem, Mark , Gifford, Hanson , Zarins, Denise , Sutton, Douglas , Thai, Erik , Gelfand, Mark , Levin, Howard R.
IPC分类号： A61N1/08 , A61N1/05 , A61N1/32 , A61B18/14 , A61B18/00 , A61N1/36
CPC分类号： A61N1/36007 , A61B8/0891 , A61B8/12 , A61B18/1206 , A61B18/1233 , A61B18/1492 , A61B18/18 , A61B2018/00071 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00904 , A61B2018/126 , A61B2018/1467 , A61M5/14 , A61M25/0023 , A61N1/0412 , A61N1/05 , A61N1/0551 , A61N1/18 , A61N1/205 , A61N1/326 , A61N1/327 , A61N1/36017 , A61N1/36057 , A61N1/3606 , A61N1/36103 , A61N1/36114 , A61N1/36117 , A61N1/36139 , A61N5/00 , A61N7/00 , A61N2007/0021 , A61N2007/003
摘要： Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.

4. 发明公开

EP2814562A4 DUAL-SIDED CURRENT CONTROLLING ELECTRODE 审中-公开
标题翻译：双面与受控电极电流
公开(公告)号：EP2814562A4
公开(公告)日：2015-10-28
申请号：EP13748855
申请日：2013-02-06
申请人： AXELGAARD MFG CO LTD , AXELGAARD JENS
发明人： AXELGAARD JENS
IPC分类号： A61N1/04 , A61N1/18
CPC分类号： A61N1/0452 , A61N1/0456 , A61N1/0492 , A61N1/18
摘要： A field controlling electrode for providing transcutaneous nerve and/or muscle stimulation to a user's body includes a conductive flexible member having a top side and a bottom side. An electrically driven master electrode, in combination with the conductive flexible member, is provided for generating a current distribution in the conductive flexible member; and an electrically undriven slave electrode disposed in a spaced apart relationship with the master electrode is provided, for focusing or controlling the generated current distribution over an area of a user's body.

5. 发明公开

EP2561905A8 Apparatus for renal neuromodulation 有权转让
标题翻译：肾神经调节装置
公开(公告)号：EP2561905A8
公开(公告)日：2013-04-03
申请号：EP12180431.4
申请日：2005-10-05
申请人： Medtronic Ardian Luxembourg S.à.r.l.
发明人： Deem, Mark , Gifford, Hanson , Zarins, Denise , Sutton, Douglas , Thai, Erik , Gelfand, Mark , Levin, Howard R.
IPC分类号： A61N1/08 , A61N1/05 , A61N1/32 , A61B18/14
CPC分类号： A61N1/36007 , A61B8/0891 , A61B8/12 , A61B18/1206 , A61B18/1233 , A61B18/1492 , A61B18/18 , A61B2018/00071 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00904 , A61B2018/126 , A61B2018/1467 , A61M5/14 , A61M25/0023 , A61N1/0412 , A61N1/05 , A61N1/0551 , A61N1/18 , A61N1/205 , A61N1/326 , A61N1/327 , A61N1/36017 , A61N1/36057 , A61N1/3606 , A61N1/36103 , A61N1/36114 , A61N1/36117 , A61N1/36139 , A61N5/00 , A61N7/00 , A61N2007/0021 , A61N2007/003
摘要： Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
摘要翻译：提供了使用脉冲电场进行肾神经调节的方法和装置以实现电穿孔或电融合。预计肾神经调节（例如去神经支配）可以减少急性心肌梗塞的扩大，减少或阻止与充血性心力衰竭有关的形态学变化的发作，和/或在治疗中有效晚期肾脏疾病。本发明的实施例被配置用于脉冲电场的经皮血管内递送以实现这种神经调节。

6. 发明公开

EP2561902A1 Methods and apparatus for renal neuromodulation 失效
标题翻译： Vorrichtung zur Nierenneumodulation
公开(公告)号：EP2561902A1
公开(公告)日：2013-02-27
申请号：EP12180426.4
申请日：2005-10-05
申请人： Medtronic Ardian Luxembourg S.à.r.l.
发明人： Deem, Mark , Gifford, Hanson , Zarins, Denise , Sutton, Douglas , Thai, Erik , Gelfand, Mark , Levin, Howard R.
IPC分类号： A61N1/08 , A61N1/05 , A61N1/32 , A61B18/14
CPC分类号： A61N1/36007 , A61B8/0891 , A61B8/12 , A61B18/1206 , A61B18/1233 , A61B18/1492 , A61B18/18 , A61B2018/00071 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00904 , A61B2018/126 , A61B2018/1467 , A61M5/14 , A61M25/0023 , A61N1/0412 , A61N1/05 , A61N1/0551 , A61N1/18 , A61N1/205 , A61N1/326 , A61N1/327 , A61N1/36017 , A61N1/36057 , A61N1/3606 , A61N1/36103 , A61N1/36114 , A61N1/36117 , A61N1/36139 , A61N5/00 , A61N7/00 , A61N2007/0021 , A61N2007/003
摘要： Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
摘要翻译：提供使用脉冲电场进行肾脏神经调节以实现电穿孔或电融合的方法和装置。预期肾神经调节（例如去神经支配）可以减少急性心肌梗死的扩张，减少或预防与充血性心力衰竭有关的形态学变化的发生，和/或有效治疗晚期肾脏疾病。本发明的实施例被配置用于经皮血管内递送脉冲电场以实现这种神经调节。

7. 发明授权

EP2272454B1 Electrosurgical jaws with offset knife 有权转让
标题翻译：电端子与偏移叶片
公开(公告)号：EP2272454B1
公开(公告)日：2012-02-08
申请号：EP10168705.1
申请日：2010-07-07
申请人： Tyco Healthcare Group, LP
发明人： Bucciaglia, Joseph D. , Chojin, Edward M. , Horner, Glenn A.
IPC分类号： A61B18/14 , A61B17/29
CPC分类号： A61B17/32 , A61B17/2909 , A61B17/295 , A61B18/1445 , A61B2017/2911 , A61B2017/2919 , A61B2017/2922 , A61B2017/2945 , A61B2017/320052 , A61B2018/00404 , A61B2018/00601 , A61B2018/0063 , A61B2018/1412 , A61B2018/1432 , A61B2018/1455 , A61B2090/034 , A61N1/18
摘要： A forceps, comprising: a housing having a shaft attached thereto, the shaft having a longitudinal axis defined therethrough and an end effector assembly disposed at a distal end thereof, wherein the end effector assembly includes: first and second jaw members disposed in opposing relation relative to one another and moveable from a first position to a second position for grasping tissue therebetween, each of the jaw members including a proximal flange adapted to communicate with a drive assembly for moving the jaw members between the first and second positions and at least one of the jaw members including a knife channel defined therein, a proximal end of the knife channel offset from the longitudinal axis defined through the shaft; and a knife guide assembled adjacent an outer surface of one of the proximal flanges of the jaw members on the same side as the proximal end of the knife channel, the knife guide defining a knife path therein configured to guide a knife into the knife channel for translation therethrough.

8. 发明公开

EP2329859A1 Apparatus for renal neuromodulation 审中-公开
标题翻译： VernrichtungfürNeuromodulation der Nieren
公开(公告)号：EP2329859A1
公开(公告)日：2011-06-08
申请号：EP10190952.1
申请日：2005-10-05
申请人： Ardian, Inc.
发明人： Deem, Mark , Gifford, Hanson , Demarais, Denise , Sutton, Douglas , Thai, Erik , Gelfand, Mark , Levin, Howard R.
IPC分类号： A61N1/08
CPC分类号： A61N1/36007 , A61B8/0891 , A61B8/12 , A61B18/1206 , A61B18/1233 , A61B18/1492 , A61B18/18 , A61B2018/00071 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00904 , A61B2018/126 , A61B2018/1467 , A61M5/14 , A61M25/0023 , A61N1/0412 , A61N1/05 , A61N1/0551 , A61N1/18 , A61N1/205 , A61N1/326 , A61N1/327 , A61N1/36017 , A61N1/36057 , A61N1/3606 , A61N1/36103 , A61N1/36114 , A61N1/36117 , A61N1/36139 , A61N5/00 , A61N7/00 , A61N2007/0021 , A61N2007/003
摘要： Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
摘要翻译：提供使用脉冲电场进行肾脏神经调节以实现电穿孔或电融合的方法和装置。预期肾神经调节（例如去神经支配）可以减少急性心肌梗死的扩张，减少或预防与充血性心力衰竭有关的形态学变化的发生，和/或有效治疗晚期肾脏疾病。本发明的实施例被配置用于经皮血管内递送脉冲电场以实现这种神经调节。

9. 发明公开

EP2104462A4 NON-INVASIVE ULTRASOUND-GUIDED BODY CONTOURING USING SKIN CONTACT COOLING 审中-公开
标题翻译：皮肤接触冷却无创超声基于身体轮廓
公开(公告)号：EP2104462A4
公开(公告)日：2009-11-04
申请号：EP07827423
申请日：2007-11-25
申请人： PERL PAUL K , MUNOZ FRANCISCO ARRIAZA
发明人： PERL PAUL K , MUNOZ FRANCISCO ARRIAZA
IPC分类号： A61N7/00
CPC分类号： A61H23/0245 , A61B8/546 , A61B2017/00026 , A61B2017/00106 , A61H2201/0207 , A61H2201/0214 , A61H2201/0242 , A61H2201/025 , A61H2201/0285 , A61H2201/10 , A61N1/18 , A61N7/00 , A61N2007/0008 , A61N2007/0073

10. 发明公开

EP1802370A4 METHODS AND APPARATUS FOR RENAL NEUROMODULATION 有权
标题翻译：方法和设备肾神经调节
公开(公告)号：EP1802370A4
公开(公告)日：2009-10-21
申请号：EP05806045
申请日：2005-10-05
申请人： ARDIAN INC
发明人： DEEM MARK , GIFFORD HANSON III , DEMARAIS DENISE , SUTTON DOUGLAS , THAI ERIK , GELFAND MARK , LEVIN HOWARD R
IPC分类号： A61N1/08 , A61F2/958 , A61N1/05 , A61N1/32 , A61N1/36
CPC分类号： A61N1/36007 , A61B8/0891 , A61B8/12 , A61B18/1206 , A61B18/1233 , A61B18/1492 , A61B18/18 , A61B2018/00071 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00904 , A61B2018/126 , A61B2018/1467 , A61M5/14 , A61M25/0023 , A61N1/0412 , A61N1/05 , A61N1/0551 , A61N1/18 , A61N1/205 , A61N1/326 , A61N1/327 , A61N1/36017 , A61N1/36057 , A61N1/3606 , A61N1/36103 , A61N1/36114 , A61N1/36117 , A61N1/36139 , A61N5/00 , A61N7/00 , A61N2007/0021 , A61N2007/003
摘要： Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.

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