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1. 发明授权

EP3171933B1 PRECISION CHEMICAL ABLATION AND TREATMENT OF TISSUES 有权
公开(公告)号：EP3171933B1
公开(公告)日：2024-08-14
申请号：EP15825209.8
申请日：2015-07-23
IPC分类号： A61N1/30
CPC分类号： A61B5/6853 , A61B5/7282 , A61B5/0538 , A61B5/055 , A61B5/4035 , A61B5/4839 , A61B5/4848 , A61N1/36025 , A61N1/37247 , A61N1/0456 , A61K31/045 , A61B5/287

2. 发明授权

EP3906091B1 ULTRASOUND-BASED PROTOCOL FOR OPERATING AN IMPLANTABLE DEVICE 有权
公开(公告)号：EP3906091B1
公开(公告)日：2024-06-26
申请号：EP20736013.2
申请日：2020-01-03
IPC分类号： A61N1/37 , A61N1/372 , A61N1/378
CPC分类号： A61N1/3605 , A61B5/01 , A61B5/021 , A61B5/024 , A61B5/14539 , A61N1/37217 , A61N1/365 , A61B5/14532 , A61N1/36053 , A61N1/3702 , A61B5/002 , A61B5/0028 , A61B2560/021920130101 , A61B5/686 , A61B5/4035 , A61B5/4047 , A61B5/4052 , A61B5/4848 , A61B5/14556 , A61B5/24

3. 发明公开

EP3405107A1 CONTROL OF VAGAL STIMULATION 有权
公开(公告)号：EP3405107A1
公开(公告)日：2018-11-28
申请号：EP17742066.8
申请日：2017-01-20
申请人： Setpoint Medical Corporation
发明人： LEVINE, Jacob, A. , FALTYS, Michael, A. , SIMON, Jesse, M.
IPC分类号： A61B5/0408 , A61N1/04 , A61N1/18 , A61N1/365 , A61N1/372
CPC分类号： A61N1/36135 , A61B5/02405 , A61B5/0456 , A61B5/4035 , A61B5/4836 , A61B5/7257 , A61N1/0556 , A61N1/36053 , A61N1/3606 , A61N1/37205 , A61N1/37247 , A61N1/3756 , A61N1/3787
摘要： Methods and apparatuses for stimulation of the vagus nerve to treat inflammation including adjusting the stimulation based on one or more metric sensitive to patient response. The one or more metrics may include heart rate variability, level of T regulatory cells, particularly memory T regulatory cells, temperature, etc. Stimulation may be provided through an implantable microstimulator.

4. 发明授权

EP2489307B1 BIOLOGICAL STATE ESTIMATION DEVICE AND COMPUTER PROGRAM 有权
公开(公告)号：EP2489307B1
公开(公告)日：2018-10-03
申请号：EP10823446.9
申请日：2010-10-14
申请人： Delta Tooling Co., Ltd.
发明人： FUJITA, Etsunori , OGURA, Yumi , MAEDA, Shinichiro , OCHIAI, Naoki
IPC分类号： A61B5/18 , A61B5/00 , B60K28/06 , B60W40/08
CPC分类号： A61B5/18 , A61B5/4035 , A61B5/4809 , A61B5/6893 , A61B5/7239 , A61B5/7242 , A61B5/742 , A61B5/744 , B60W2040/0872
摘要： A biological body state estimation device which can capture not only activities of autonomous nerves but also an activated state of a brain function is provided. The biological body state estimation device is configured such that a homeostatic function level is sorted and acquired in a plurality of stages by using a biological signal obtained from the upper body of a person and each stage of the homeostatic function level is plotted in a time series in accordance with a time axis indicated on the lateral axis and displayed as a graph by display means. It is preferable that the highest part on the vertical axis of the graph is displayed as a highly active state and the lowest part as a function decline state. As a result, a state of fluctuation due to the autonomous nerves as an attempt to maintain homeostasis, progress of a feeling of fatigue, and a state stimulated by activation of the brain can be captured as a periodic function. Moreover, a sleep prediction phenomenon can be also captured.

5. 发明公开

EP3302244A2 INJECTING AND MONITORING NERVOUS TISSUE 审中-公开
标题翻译：注射和监测神经组织
公开(公告)号：EP3302244A2
公开(公告)日：2018-04-11
申请号：EP16802672.2
申请日：2016-06-02
申请人： Navix International Limited
发明人： LICHTENSTEIN, Yoav , SCHWARTZ, Yitzhack , BEN-HAIM, Shlomo
IPC分类号： A61B5/00
CPC分类号： A61B5/4848 , A61B5/04001 , A61B5/4035 , A61B5/4893 , A61B5/6857 , A61B5/6882 , A61B18/1492 , A61B34/10 , A61B2018/00351 , A61B2018/00434 , A61B2018/00577 , A61B2018/00839 , A61B2018/1425 , A61B2018/1435 , A61B2018/1475 , A61B2218/007 , A61B2562/0209 , A61M5/007 , A61M5/178 , A61M2202/0484 , A61N1/0502 , A61N1/0551 , A61N1/36017
摘要： Sensing and/or treating GPs or other components of the ANS. Optionally, sensing is from within the GP, for example, using a helical needle with at least one electrode. Optionally, treatment is by injection of a neuromodulator chemical into the GP. In some embodiments, means are provided to reduce the migration of the neuromodulator away from the GP.

6. 发明公开

EP3173027A4 HEART FAILURE EVALUATION METHOD AND DIAGNOSIS DEVICE 有权转让
公开(公告)号：EP3173027A4
公开(公告)日：2018-04-11
申请号：EP15824273
申请日：2015-07-22
申请人： TEIJIN PHARMA LTD
发明人： MATSUMOTO SADAYOSHI
IPC分类号： A61B10/00 , A61B5/00 , A61B5/02 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/029 , A61B5/08 , A61B5/091 , A61B5/145 , G16H50/30
CPC分类号： A61B5/02 , A61B5/02007 , A61B5/02028 , A61B5/0205 , A61B5/021 , A61B5/02405 , A61B5/029 , A61B5/08 , A61B5/0816 , A61B5/091 , A61B5/14542 , A61B5/4035 , A61B5/7264 , A61B5/7275 , A61B10/00 , A61B2505/07 , G16H50/30
摘要： Provided are a means to detect a plurality of dynamics, a processing unit that calculates a temporal change in the detected dynamics, and an evaluation device that determines exacerbation of clinical conditions in heart failure of a patient based on the calculated change in the patient's dynamics over time. The present invention makes it possible to detect, early and with high accuracy, that the onset of acute heart failure is imminent.

7. 发明公开

EP3171933A4 PRECISION CHEMICAL ABLATION AND TREATMENT OF TISSUES 审中-实审
公开(公告)号：EP3171933A4
公开(公告)日：2018-03-21
申请号：EP15825209
申请日：2015-07-23
申请人： TOTH LANDY , SCHWARTZ ROBERT
发明人： TOTH LANDY , SCHWARTZ ROBERT
IPC分类号： A61N1/30
CPC分类号： A61K31/045 , A61B5/0422 , A61B5/0538 , A61B5/055 , A61B5/4035 , A61B5/4839 , A61B5/4848 , A61B5/6853 , A61B5/7282 , A61B18/06 , A61B2018/0022 , A61B2018/068 , A61K47/38 , A61K49/0043 , A61N1/0456 , A61N1/36025 , A61N1/37247
摘要： Compositions, systems, devices, and methods for performing precise chemical treatment of tissues are disclosed. Systems, devices, and methods for administering a chemical agent to one or more a precise regions within a tissue mass are disclosed. Compositions, systems, devices, and methods for treating targeted regions within a tissue mass are disclosed.

8. 发明授权

EP2853937B1 Goggle-like mobile apparatus and method for recording images of a pupil of a person 有权转让
标题翻译：用于记录人的瞳孔图像的护目镜状移动装置和方法
公开(公告)号：EP2853937B1
公开(公告)日：2017-11-01
申请号：EP13186191.6
申请日：2013-09-26
申请人： Stickel, Manfred
发明人： Stickel, Manfred
IPC分类号： G02C5/00 , G02C11/00 , A61F9/02 , A61B3/11 , A61B5/00
CPC分类号： A61B3/112 , A61B5/4035 , A61F9/029

9. 发明公开

EP3212075A1 SYSTEM FOR THE ANALYSIS OF THE DAILY HEART RHYTHM AUTONOMIC NERVOUS SYSTEM BALANCE 有权
标题翻译：系统的分析每日心脏节律自主神经系统平衡
公开(公告)号：EP3212075A1
公开(公告)日：2017-09-06
申请号：EP15724766.9
申请日：2015-04-13
申请人： UAB Metapro Holding
发明人： STANKUS, Albinas
IPC分类号： A61B5/0452 , A61B5/00 , A61B5/024 , G06F19/00
CPC分类号： A61B5/4035 , A61B5/02405 , A61B5/0452 , A61B5/0456 , A61B5/4857 , A61B5/7203 , A61B5/743 , G16H10/60 , G16H15/00 , G16H50/20
摘要： The present invention collects data on circadian intervals between two cardiac contractions (RR intervals) and, on the basis of the collected data on circadian RR intervals, provides a system for analysis of the human circadian heart rhythm autonomic nervous system balance, and analysis of heart rate (HR). The invention focuses on HR fluctuations that are divided into three groups: slow fluctuations of the circadian period, higher frequencies compared with circadian, and chaotic. The division into parts is executed by applying adequate empiric and mathematical methods to determine a series of envelope curves, closely and individually related to the principal circadian series, followed by their separation from the input HR series, and then applying HR variability (HRV) methods to increase accuracy of the analysis of HRV results and add new HR regulation criteria to the analysis outcomes.
摘要翻译：一种用于分析昼夜节律心脏自律神经系统平衡的分析系统，该分析系统具有用于在从RR间隔序列去除伪像和心律失常后执行以下步骤的工具：RR间期序列的混沌部分的识别和混沌部分分析; 从RR间隔序列中分离混沌部分并获得干净的昼夜节律RR系列; 采用 - 插值，重采样和归一化采集归一化的RR间期序列; 分析归一化RR间期序列的心率双峰分布和模式; 在归一化RR数据序列中识别心率昼夜节律周期; 分析归一化RR数据序列中的心律变量部分SNS和PNS调节指标; 以图形和表格形式生成获得结果的报告。

10. 发明公开

EP3007619A4 METHOD AND APPARATUS FOR AUTONOMIC NERVOUS SYSTEM SENSITIVITY-POINT TESTING 审中-公开
标题翻译： VERFAHREN UND VORRICHTUNGFÜRAUTONOME NERVENSYSTEMEMPFINDLICHKEITSPUNKTTESTS
公开(公告)号：EP3007619A4
公开(公告)日：2017-07-05
申请号：EP13886872
申请日：2013-06-13
申请人： DYANSYS INC
发明人： NAGESHWAR SRINI
IPC分类号： A61B5/053 , A61B5/00
CPC分类号： A61B5/4035 , A61B5/0002 , A61B5/0048 , A61B5/0533 , A61B5/4827 , A61B5/6815

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