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1. 发明公开

EP2366675A4 SINTERED COLORED ALUMINA OF HIGH TOUGHNESS AND HIGH TRANSLUCENCY, AND MANUFACTURING METHOD AND USES THEREFOR 有权
标题翻译：高韧性和高透光性，方法和烧结氧化铝有色及其用途
公开(公告)号：EP2366675A4
公开(公告)日：2013-04-24
申请号：EP09827526
申请日：2009-11-13
申请人： TOSOH CORP
发明人： YAMASHITA ISAO , TSUKUMA KOJI
IPC分类号： C04B35/115 , A61C7/14 , A61C7/28 , A61L27/10 , C04B35/645
CPC分类号： A61L27/105 , C04B35/115 , C04B35/6455 , C04B2235/3201 , C04B2235/3203 , C04B2235/3205 , C04B2235/3206 , C04B2235/3208 , C04B2235/3213 , C04B2235/3215 , C04B2235/3232 , C04B2235/3239 , C04B2235/3262 , C04B2235/3272 , C04B2235/3279 , C04B2235/3281 , C04B2235/3287 , C04B2235/34 , C04B2235/3409 , C04B2235/3418 , C04B2235/5409 , C04B2235/5445 , C04B2235/72 , C04B2235/77 , C04B2235/786 , C04B2235/788 , C04B2235/96 , C04B2235/9661

2. 发明公开

EP2139531A4 CARRIERS FOR DRUG DELIVERY 审中-公开
标题翻译： TRÄGERFÜRARZNEIABGABE
公开(公告)号：EP2139531A4
公开(公告)日：2013-01-09
申请号：EP08724310
申请日：2008-03-28
申请人： DOXA AB
发明人： HERMANSSON LEIF , ENGQVIST HAAKAN
IPC分类号： A61L27/10 , A61K6/06 , A61K9/22 , A61K47/02 , C04B7/32
CPC分类号： A61K9/1611 , A61K9/0024 , A61L27/10 , A61L27/105 , A61L27/12 , A61L27/54 , A61L27/56 , A61L2300/602 , C04B18/021 , C04B28/06 , C04B28/18 , C04B2111/00215 , C04B2111/00836 , C04B2111/23 , C04B2111/27 , C04B14/303 , C04B14/322 , C04B14/325 , C04B18/027 , C04B20/10 , C04B14/324 , C04B14/366 , C04B16/08 , C04B38/0074 , C04B14/22 , C04B14/328 , C04B14/365
摘要： The present invention relates to chemically bonded ceramic precursor material of aluminates and silicates exhibiting a controlled release rate and properties that make the material suitable as a carrier material used in drug delivery. According to the invention, this is accomplished by selecting a microstructure based on pre-reacted phases and/or reacting phases, which contains the drugs. The present invention also relates to a cured ceramic material and a method of manufacturing said cured material. The precursor and the cured ceramic material according to the present invention can suitably be used for different types of drug intake and delivery.
摘要翻译：本发明涉及化学键合的铝酸盐和硅酸盐的陶瓷前体材料，其表现出控制释放速率和性质，使材料适合作为药物递送中使用的载体材料。根据本发明，这是通过选择基于预反应相的微观结构和/或反应含有药物的相来完成的。本发明还涉及固化的陶瓷材料和制造所述固化材料的方法。根据本发明的前体和固化陶瓷材料可适用于不同类型的药物摄取和输送。

3. 发明公开

EP1778163A4 CHEMICALLY BONDED CERAMIC MATERIAL 有权
标题翻译：化学粘合陶瓷材料
公开(公告)号：EP1778163A4
公开(公告)日：2010-02-24
申请号：EP05774832
申请日：2005-08-17
申请人： DOXA AB
发明人： ENGQVIST HAAKAN , HERMANSSON LEIF , LOEOEF JESPER , SPENGLER HAAKAN
IPC分类号： A61K6/06 , A61L20060101 , A61L27/10 , A61L27/42 , C04B28/02 , C04B28/06 , C04B28/34 , C04B35/80 , C04B35/82
CPC分类号： A61L27/42 , A61K6/0008 , A61K6/0085 , A61K6/0091 , A61K6/0612 , A61K6/0643 , A61K6/0668 , A61K6/0675 , A61L27/105 , C04B28/02 , C04B28/06 , C04B28/34 , C04B2111/00836 , C04B20/0048 , C04B24/2641 , C04B14/42 , A61K6/083 , C08L33/08

4. 发明公开

EP1270533A3 Ceramic materials, method for their production and use thereof 审中-公开
标题翻译：陶瓷材料，其制备方法及其应用
公开(公告)号：EP1270533A3
公开(公告)日：2003-06-04
申请号：EP01129367.7
申请日：2001-12-17
申请人： Zellwerk GmbH
发明人： Hoffmeister, Hans, H.W.
IPC分类号： C04B38/06 , C12N5/00 , A61L27/10
CPC分类号： C12N5/0068 , A61F2310/00203 , A61F2310/00215 , A61F2310/00227 , A61F2310/00239 , A61F2310/00251 , A61L27/025 , A61L27/10 , A61L27/105 , A61L27/427 , A61L2400/18 , C04B35/14 , C04B35/46 , C04B35/486 , C04B35/50 , C04B38/06 , C04B2111/00836 , C04B2235/3208 , C04B2235/3229 , C04B2235/3244 , C04B2235/3246 , C04B2235/3256 , C04B2235/3258 , C04B2235/326 , C04B2235/3268 , C04B2235/3418 , C04B2235/425 , C04B2235/5427 , C04B2235/5436 , C04B2235/5445 , C04B2235/5472 , C04B2235/77 , C04B2235/80 , C04B2235/85 , C12N2533/14 , C04B35/00
摘要： The present invention relates to ceramic materials comprising a crystalline core oxide ceramic dispersed with an amorphous polyanionic intergranular phase as well as methods and materials for the production of said ceramic materials, articles comprising said ceramic materials and uses thereof.

5. 发明授权

EP1080737B1 Carrier for a soft tissue augmentation material 失效
标题翻译：一种用于软组织填充材料支撑
公开(公告)号：EP1080737B1
公开(公告)日：2003-04-09
申请号：EP00121050.9
申请日：1993-02-05
申请人： Bioform Inc.
发明人： Hubbard, William G.
IPC分类号： A61L27/52 , A61F2/00 , A61L27/10 , A61L27/44 , A61L27/46
CPC分类号： A61L27/46 , A61F2/0036 , A61L27/10 , A61L27/105 , A61L27/12 , A61L27/20 , A61L27/222 , A61L27/446 , A61L27/52 , A61L2400/06 , C04B35/447 , C04B35/6365 , C08L1/26
摘要： A permanent, biocompatible material for soft tissue augmentation. The biocompatible material comprises a matrix of smooth, round, finely divided, substantially spherical particles of a biocompatible ceramic material, close to or in contact with each other, which provide a scaffold or lattice for autogenous, three dimensional, randomly oriented, non-scar soft tissue growth at the augmentation site. The augmentation material can be homogeneously suspended in a biocompatible, resorbable lubricious gel carrier comprising a polysaccharide. This serves to improve the delivery of the augmentation material by injection to the tissue site where augmentation is desired. The augmentation material is especially suitable for urethral sphincter augmentation, for treatment of incontinence, for filling soft tissue voids, for creating soft tissue blebs, for the treatment of unilateral vocal cord paralysis, and for mammary implants. It can be injected intradermally, subcutaneously or can be implanted.

6. 发明授权

EP1035878B1 KÜNSTLICHES GELENK EINER PROTHESE 无效
标题翻译：人工关节假体
公开(公告)号：EP1035878B1
公开(公告)日：2001-10-10
申请号：EP98964460.4
申请日：1998-11-30
申请人： Ceramtec AG Innovative Ceramic Engineering
发明人： DEPPISCH, Werner , PFAFF, Hans-Georg , WILLMANN, Gerd
IPC分类号： A61L27/00 , A61F2/32
CPC分类号： A61L27/10 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3662 , A61F2002/30332 , A61F2002/30968 , A61F2002/3611 , A61F2002/3625 , A61F2002/365 , A61F2220/0033 , A61F2310/00011 , A61F2310/00029 , A61F2310/00203 , A61F2310/00239 , A61L27/105 , C04B35/4885
摘要： Prostheses with artificial joints have only a few metallic and ceramic materials whose compatibility with human or animal tissue has been established. These materials, however, cannot be combined with one another in any manner if a friction pairing occurs as a result, for example, in the case of artificial joints. With artificial joints, joint partners are required to have good mechanical properties as well as tribological properties. According to the invention, a sintered material is thus provided which is comprised of zircon oxide with an addition of 0.1 to 40 wt. % aluminum oxide. This sintered material enables an artificial joint of a prosthesis whose other ceramic materials are comprised of aluminum oxide or zircon oxide with the given proportions of aluminum oxide to be assembled with joint partners.

7. 发明公开

EP0918498A4 IMPROVED TISSUE INJECTABLE COMPOSITION AND METHOD OF USE 失效
标题翻译：注射组合物在人体组织及使用方法
公开(公告)号：EP0918498A4
公开(公告)日：2001-04-11
申请号：EP97931215
申请日：1997-06-17
申请人： ADVANCED UROSCIENCE
发明人： LAWIN TIMOTHY P , KLEIN DEAN
IPC分类号： A61F2/00 , A61F2/04 , A61K9/50 , A61K47/26 , A61K47/38 , A61L27/00 , A61L27/30 , A61F2/08 , A61F2/12
CPC分类号： A61K9/501 , A61F2/0004 , A61F2/0059 , A61F2310/00574 , A61L27/08 , A61L27/105 , A61L27/303 , A61L27/50
摘要： An improved biocompatible composition consisting of physiologically stable beads or particles carried in a lubricative suspension, solution, other fluid or gel. The composition is intended to be delivered into the body through a small-bored needle, cannula, or other catheter into a tissue site for the purpose of augmenting the tissue. In particular, the composition is useful for augmenting tissue in the area of the cardiac orifice of the stomach to reduce gastric reflux, in the area of the internal or external sphincter of the anal canal to reduce fecal incontinence or in the area of urethral tissue for the purpose of treating urinary incontinence.

8. 发明公开

EP1080737A1 Carrier for a soft tissue augmentation material 失效
标题翻译：一种用于软组织填充材料支撑
公开(公告)号：EP1080737A1
公开(公告)日：2001-03-07
申请号：EP00121050.9
申请日：1993-02-05
申请人： Bioform Inc.
发明人： Hubbard, William G.
IPC分类号： A61L27/52 , A61F2/00 , A61L27/10 , A61L27/44 , A61L27/46
CPC分类号： A61L27/46 , A61F2/0036 , A61L27/10 , A61L27/105 , A61L27/12 , A61L27/20 , A61L27/222 , A61L27/446 , A61L27/52 , A61L2400/06 , C04B35/447 , C04B35/6365 , C08L1/26
摘要： A permanent, biocompatible material for soft tissue augmentation. The biocompatible material comprises a matrix of smooth, round, finely divided, substantially spherical particles of a biocompatible ceramic material, close to or in contact with each other, which provide a scaffold or lattice for autogenous, three dimensional, randomly oriented, non-scar soft tissue growth at the augmentation site. The augmentation material can be homogeneously suspended in a biocompatible, resorbable lubricious gel carrier comprising a polysaccharide. This serves to improve the delivery of the augmentation material by injection to the tissue site where augmentation is desired. The augmentation material is especially suitable for urethral sphincter augmentation, for treatment of incontinence, for filling soft tissue voids, for creating soft tissue blebs, for the treatment of unilateral vocal cord paralysis, and for mammary implants. It can be injected intradermally, subcutaneously or can be implanted.

9. 发明公开

EP0976697A1 Alumina sintered body and process for producing the same 有权
标题翻译： Aluminiumoxidsinterkörper和Verfahren zu seiner Herstellung
公开(公告)号：EP0976697A1
公开(公告)日：2000-02-02
申请号：EP99114634.1
申请日：1999-07-26
申请人： Sumitomo Chemical Company, Limited
发明人： Watanabe, Hisashi , Uchida, Yoshio
IPC分类号： C04B35/111 , A61L27/00 , H01L21/68
CPC分类号： A61L27/105 , C04B35/111 , H01L21/6838
摘要： A process for producing a polycrystalline alumina sintered body which comprises the steps of:

subjecting alumina powder to ultrasonic irradiation, mechanical stirring not using a grinding medium, or ultrasonic irradiation and mechanical stirring not using a grinding medium, resulting in slurry dispersed in a solvent;
drying and forming said slurry to produce a green body; and then
sintering said green body in an air atmosphere at a temperature in the range of 1400 °C to 1800 °C;
wherein said alumina powder having a purity of 99.99 wt% or more comprises a polyhedral particle having substantially no fractured surface, and comprises α alumina particles having polyhedral shape; a D/H ratio of from 0.5 or more to 3.0 or less; the number-average particle size of from 0.1 µ m or more to 1.0 µm or less; a D90/D10 ratio of 7 or less.
摘要翻译：一种多晶氧化铝烧结体的制造方法，其特征在于，包括以下步骤：使氧化铝粉末进行超声波照射，不使用研磨介质的机械搅拌，或者不使用研磨介质的超声波照射和机械搅拌，使浆料分散在溶剂中; 干燥和形成所述浆料以产生生坯; 然后在空气气氛中在1400〜1800℃的温度范围内烧结生坯; 其中纯度为99.99重量％以上的所述氧化铝粉末包含基本上没有断裂表面的多面体颗粒，并且包含具有多面体形状的α氧化铝颗粒; 0.5以上3.0以下的D / H比; 数均粒径为0.1μm以上至1.0μm以下; D90 / D10的比例为7以下。

10. 发明公开

EP0918498A1 IMPROVED TISSUE INJECTABLE COMPOSITION AND METHOD OF USE 失效
标题翻译：注射组合物在人体组织
公开(公告)号：EP0918498A1
公开(公告)日：1999-06-02
申请号：EP97931215.0
申请日：1997-06-17
申请人： Advanced Uroscience
发明人： LAWIN, Timothy, P. , KLEIN, Dean
IPC分类号： A61F2 , A61K9 , A61K47 , A61L27
CPC分类号： A61K9/501 , A61F2/0004 , A61F2/0059 , A61F2310/00574 , A61L27/08 , A61L27/105 , A61L27/303 , A61L27/50
摘要： An improved biocompatible composition consisting of physiologically stable beads or particles carried in a lubricative suspension, solution, other fluid or gel. The composition is intended to be delivered into the body through a small-bored needle, cannula, or other catheter into a tissue site for the purpose of augmenting the tissue. In particular, the composition is useful for augmenting tissue in the area of the cardiac orifice of the stomach to reduce gastric reflux, in the area of the internal or external sphincter of the anal canal to reduce fecal incontinence or in the area of urethral tissue for the purpose of treating urinary incontinence.

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