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1. 发明授权

EP2688499B1 TISSUE REPAIR WITH SPACE-SEEKING SPIRALS OF FILAMENT 失效
标题翻译：组织修复与空间寻找螺旋丝
公开(公告)号：EP2688499B1
公开(公告)日：2017-09-27
申请号：EP12723539.8
申请日：2012-03-23
申请人： Yeung, Jeffrey E. , Yeung, Teresa T.
发明人： Yeung, Jeffrey E. , Yeung, Teresa T.
IPC分类号： A61F2/00 , A61B17/04 , A61B17/00 , A61F2/30 , A61F2/44 , A61F2/46 , A61B17/70 , A61B17/88 , A61B17/34
CPC分类号： A61F2/442 , A61B17/0483 , A61B17/3468 , A61B17/7061 , A61B17/7094 , A61B17/8852 , A61B2017/00805 , A61B2017/00867 , A61F2/0036 , A61F2/4611 , A61F2002/30289 , A61F2002/30294 , A61F2002/30677 , A61F2002/444 , A61F2002/4495 , A61F2002/4635 , A61F2210/0061 , A61F2230/0091 , A61F2250/0067 , A61F2310/00598 , A61F2310/0061 , A61F2310/0097 , A61F2310/00976 , A61F2310/00982
摘要： A distal portion of a filament is extended beyond the distal end of a needle with a gripper. The needle with the extended filament is inserted into a cannula with snagging points at the distal opening of the cannula in tissue. The snagging points of the cannula hook and retain the distal portion of the filament. During partial withdrawal of the needle, a section of filament is deposited in the lumen of the cannula between the distal ends of the needle and cannula. When the needle is re-advanced, the section of filament is expelled or pushed out of the cannula into tissue. The needle is then rotated; the gripper engages and spirals the expelled filament, burrowing into tissue. The needle can further advanced to push and pack the spiral of filament deep into the tissue. The knot-like filament spiral is individually formed by rotation of the needle and friction between the extended filament and tissue. The process of needle partial withdrawal, re-advancement, rotation and pushing is repeated to pack and fill the tissue with interconnecting spirals of filament to prevent migration from tissue. Spiraling of the filament driven by the rotating needle is space seeking, filling, fitting or conforming to fortify, bulk, fill, cushion or repair the tissue. Bulking with filament spirals can repair degenerated disc, urinary incontinence, fecal incontinence or other defective tissue. The filament spirals can also be used as a suture anchor deep within tissue.
摘要翻译：用夹子将细丝的远端部分延伸到针的远端之外。将具有延长细丝的针插入套管中，在套管的远侧开口处的组织中具有阻断点。套管的钩挂点钩住并保持细丝的远端部分。在针的部分撤回期间，一部分细丝在针和套管的远端之间沉积在套管的内腔中。当针头再次前进时，细丝部分被排出或推出套管进入组织。针然后旋转; 抓爪啮合并螺旋排出的细丝，钻入组织。针可以进一步推进以将丝的螺旋深深地推入组织中。结状细丝螺旋通过针的旋转和延伸细丝与组织之间的摩擦而单独形成。重复针部分撤回，重新推进，旋转和推动的过程以用相互连接的细丝螺旋来填充和填充组织以防止从组织移动。由旋转针驱动的细丝的螺旋化是空间寻找，填充，配合或符合强化，填充，填充，缓冲或修复组织。用丝状螺旋进行膨胀可修复退化椎间盘，尿失禁，大便失禁或其他有缺陷的组织。丝状螺旋也可以用作组织深处的缝合锚钉。

2. 发明授权

EP1981558B1 SUTURABLE DURAL AND MENINGEAL REPAIR PRODUCT COMPRISING COLLAGEN MATRIX 有权
标题翻译：胶原蛋白基质DURA和脑膜上缝合修补产品
公开(公告)号：EP1981558B1
公开(公告)日：2012-12-12
申请号：EP07717864.8
申请日：2007-01-12
申请人： Integra Lifesciences Corporation
发明人： ARCHIBALD, Simon, J. , SPILKER, Mark , INGRAM, Ronald, T. , BRITTAN, Jeffrey, M.
IPC分类号： A61F2/00 , A61L27/24 , A61L27/56 , A61K35/30 , A61L27/50
CPC分类号： A61L27/24 , A61B17/06166 , A61F2/0077 , A61F2240/001 , A61F2240/004 , A61F2250/0015 , A61F2250/0023 , A61F2310/00365 , A61F2310/00982 , A61L27/50 , A61L27/56 , A61L2430/32

3. 发明授权

EP1296612B1 DENTAL IMPLANT HAVING A DUAL BIO-AFFINITY COLLAR 有权转让
标题翻译：牙种植体双BIOAFFINITÄTSKRAGEN
公开(公告)号：EP1296612B1
公开(公告)日：2011-09-28
申请号：EP01983914.1
申请日：2001-06-19
申请人： BIOLOK International, Inc.
发明人： RICCI, John , ALEXANDER, Harold , NAIMAN, Charles (dec.), by Naiman, Harriet, Exec. , HOLLANDER, Bruce, L. , KOZAK, Ingo
IPC分类号： A61C8/00
CPC分类号： A61B17/68 , A61C8/0006 , A61C8/0012 , A61C8/0013 , A61C8/0018 , A61C2008/0046 , A61F2/30767 , A61F2/30771 , A61F2/3094 , A61F2/36 , A61F2/367 , A61F2/3672 , A61F2/3676 , A61F2/38 , A61F2/3804 , A61F2/40 , A61F2/4202 , A61F2/4241 , A61F2/468 , A61F2002/0086 , A61F2002/009 , A61F2002/30028 , A61F2002/30029 , A61F2002/30112 , A61F2002/30136 , A61F2002/30153 , A61F2002/30158 , A61F2002/30322 , A61F2002/30808 , A61F2002/30818 , A61F2002/3082 , A61F2002/30823 , A61F2002/30828 , A61F2002/30836 , A61F2002/30838 , A61F2002/30879 , A61F2002/30883 , A61F2002/30892 , A61F2002/30906 , A61F2002/30925 , A61F2002/3093 , A61F2002/30932 , A61F2002/30952 , A61F2002/3097 , A61F2002/3611 , A61F2002/3625 , A61F2230/0004 , A61F2230/0019 , A61F2230/0026 , A61F2250/0026 , A61F2250/0051 , A61F2310/00017 , A61F2310/00023 , A61F2310/00179 , A61F2310/00329 , A61F2310/00407 , A61F2310/00616 , A61F2310/00796 , A61F2310/00928 , A61F2310/00976 , A61F2310/00982 , A61L27/38 , A61L27/50 , A61L2400/18 , A61L2430/12 , B23K26/06 , B23K26/066 , B23K2203/04 , B23K2203/14
摘要： A dental implant (100) comprises a solid elongated body including a longitudinal axis having distal and proximal ends in which the proximal end includes a collar (120) having an axial length in a range of about 1 to about 3 millimeters. The collar exhibits a proximal (26) and a distal segment (28) in which the proximal segment includes a surface texture adapted for the promotion of osseo-integration of surrounding preferably cortical bone (14). Either one or the other of the sub-segments is provided with an ordered microgeometric repetitive surface pattern in the form of alternating ridges and grooves, each having a fixed or established width in a range of about 2.0 to about 25 microns and a fixed or established depth in a range of about 2.0 to about 25 microns, in which the microgeometric repetitive patterns define a guide for preferential promotion of the rate, orientation and direction of growth colonies of cells of the maxillofacial bone or tissue which is in contact with the surface pattern.

4. 发明公开

EP2234559A1 IMPLANT PELLETS AND METHODS FOR PERFORMING BONE AUGMENTATION AND PRESERVATION 审中-公开
标题翻译：加拿大维多利亚州FÜRKNOCHENAUFBAU UNDERHALTUNG的IMPLANTATKUGELN
公开(公告)号：EP2234559A1
公开(公告)日：2010-10-06
申请号：EP09700423.8
申请日：2009-01-08
申请人： Innovative Health Technologies, Llc
发明人： KAIGLER, Darnell, Sr.
IPC分类号： A61C8/00
CPC分类号： A61C8/0006 , A61C8/0013 , A61C8/0016 , A61C2008/0084 , A61F2/2803 , A61F2002/2817 , A61F2002/3092 , A61F2002/30957 , A61F2310/00203 , A61F2310/00239 , A61F2310/00293 , A61F2310/00329 , A61F2310/00365 , A61F2310/00982 , B33Y80/00
摘要： Embodiments described herein are related to pellets that are placed within an extraction site that is in need of bone augmentation and preservation. The pellets are typically cylindrical in shape and comprise a material and a polymer coating. The goal of the pellets are to encourage sufficient new bone growth that jaw bone deterioration is prevented. The pellets create, arrange, and assemble an ideal growth environment for new bone growth to rapidly grow and preserve the original contours of an individual's jaw bone.
摘要翻译：本文描述的实施方案涉及放置在需要骨增强和保存的提取部位内的丸粒。颗粒通常是圆柱形的并且包括材料和聚合物涂层。丸的目的是鼓励足够的新骨生长，阻止颚骨恶化。颗粒创造，安排和组装一个理想的生长环境，用于新骨生长，以快速生长和保留个体颚骨的原始轮廓。

5. 发明公开

EP2211782A1 BESCHICHTETES GRANULAT ZUR NEUBILDUNG VON KNOCHENMATERIAL 审中-公开
标题翻译：包衣颗粒对新骨材料
公开(公告)号：EP2211782A1
公开(公告)日：2010-08-04
申请号：EP08715436.5
申请日：2008-01-22
申请人： Alexakis, Antonis
发明人： Alexakis, Antonis
IPC分类号： A61F2/28 , A61L24/02 , A61L27/58
CPC分类号： A61L27/58 , A61C8/0006 , A61F2/0077 , A61F2/2803 , A61F2/30767 , A61F2002/2835 , A61F2002/30062 , A61F2002/30064 , A61F2210/0004 , A61F2310/00347 , A61F2310/00982 , A61L27/24 , A61L27/3604 , A61L2430/02
摘要： The invention relates to coated granules (3) for promoting new bone formation, particularly in the jaw. It comprises a material resorbable by the human or animal body, wherein the granules (3) have a cavity-filling granule shape on a human or animal bone substrate (1).

6. 发明公开

EP2112934A2 POROUS SUBSTRATES FOR IMPLANTATION 审中-公开
标题翻译：多孔基材植入
公开(公告)号：EP2112934A2
公开(公告)日：2009-11-04
申请号：EP08716954.6
申请日：2008-02-19
申请人： National University of Ireland, Galway
发明人： APATSIDIS, Dimitrios , RYAN, Garrett , PANDIT, Abhay
IPC分类号： A61L27/56 , A61F2/44
CPC分类号： A61L27/56 , A61B17/70 , A61B17/80 , A61B17/866 , A61C8/0012 , A61F2/28 , A61F2/30724 , A61F2/30767 , A61F2/3094 , A61F2/367 , A61F2/3676 , A61F2/4425 , A61F2/4455 , A61F2/468 , A61F2002/2817 , A61F2002/30004 , A61F2002/30011 , A61F2002/30065 , A61F2002/30131 , A61F2002/30224 , A61F2002/30616 , A61F2002/30909 , A61F2002/3092 , A61F2002/30952 , A61F2002/30958 , A61F2002/30968 , A61F2002/30985 , A61F2210/0071 , A61F2230/0013 , A61F2230/0069 , A61F2250/0014 , A61F2250/0023 , A61F2310/00011 , A61F2310/00017 , A61F2310/00023 , A61F2310/00365 , A61F2310/00377 , A61F2310/00796 , A61F2310/00976 , A61F2310/00982 , A61F2310/00988
摘要： A porous substrate or implant for implantation into a human or animal body constructed from a structural material and having one or more regions which when implanted are subjected to a relatively lower mechanical loading. The region(s) are constructed with lesser mechanical strength by having a lesser amount of structural material in said region(s) relative to other regions. This is achieved by controlling pore volume fraction in the regions. A spacer is adapted to define an open-cell pore network by taking a model of the required porous structure, and creating the spacer to represent the required porous structure using three-dimensional modelling. Material to form the substrate about the spacer in infiltrated the scaffold structure formed.

7. 发明公开

EP1656959A2 System attaching soft tissue to an implant 有权
标题翻译： Anordnung zur Befestigung von Weichgewebe an einem Implantat
公开(公告)号：EP1656959A2
公开(公告)日：2006-05-17
申请号：EP05256900.1
申请日：2005-11-08
申请人： DePuy Products, Inc. , Purdue Research Foundation
发明人： Perla, Venu , Malaviya, Prasanna , Webster, Thomas J
IPC分类号： A61L27/56 , A61L27/32 , A61L27/50
CPC分类号： A61F2/30771 , A61B17/08 , A61F2/30 , A61F2002/30011 , A61F2002/30062 , A61F2002/30064 , A61F2002/3084 , A61F2002/3092 , A61F2002/30929 , A61F2002/3093 , A61F2002/30968 , A61F2310/00023 , A61F2310/0097 , A61F2310/00982 , A61K9/0024 , A61K9/0092 , A61L27/04 , A61L27/32 , A61L27/34 , A61L27/50 , A61L27/54 , A61L27/56 , A61L31/022 , A61L31/16 , A61L2300/414 , A61L2300/604 , A61L2300/624 , A61L2400/12 , A61L2400/18 , A61L2430/02 , C25D5/34 , C25D11/02 , Y10T428/24355
摘要： A construct for enhancing attachment of a soft tissue to a metal implant comprises a metal implant having a porous region. The porous region exhibits a nano-textured surface and a calcified material layer coating the nano-textured surface. A kit for repairing a diarthrodial joint comprises the construct together with a calcified material layer coating the nano-textured surface, and an extender graft comprising a naturally occurring extracellular matrix, and a mesh member coupled to the naturally occurring extracellular matrix.
摘要翻译：用于增强软组织附着到金属植入物的构造物包括具有多孔区域的金属植入物。多孔区域表现出纳米纹理表面和涂覆纳米纹理表面的钙化材料层。用于修复关节内关节的试剂盒包括与包被纳米纹理表面的钙化材料层以及包含天然存在的细胞外基质的增量剂移植物和与天然存在的细胞外基质偶联的网状构件。

8. 发明公开

EP1365711A1 ORTHOPEDIC IMPLANTS HAVING ORDERED MICROGEOMETRIC SURFACE PATTERNS 有权
标题翻译：与从微整形植入物表面几何格局
公开(公告)号：EP1365711A1
公开(公告)日：2003-12-03
申请号：EP02748352.8
申请日：2002-02-11
申请人： BIOLOK International, Inc.
发明人： RICCI, John , ALEXANDER, Harold , NAIMAN, Charles DI , HOLLANDER, Bruce, L. , KOZAK, Ingo , Naiman, Harriet
IPC分类号： A61F2/28
CPC分类号： A61F2/30771 , A61B17/68 , A61C8/0012 , A61C8/0013 , A61C2008/0046 , A61F2/30 , A61F2/30767 , A61F2/3094 , A61F2/32 , A61F2/36 , A61F2/367 , A61F2/3672 , A61F2/3676 , A61F2/38 , A61F2/3804 , A61F2/40 , A61F2/4202 , A61F2/4241 , A61F2/468 , A61F2002/0086 , A61F2002/009 , A61F2002/30028 , A61F2002/30029 , A61F2002/30112 , A61F2002/30136 , A61F2002/30153 , A61F2002/30158 , A61F2002/30322 , A61F2002/30808 , A61F2002/30818 , A61F2002/3082 , A61F2002/30823 , A61F2002/30828 , A61F2002/30836 , A61F2002/30838 , A61F2002/30879 , A61F2002/30883 , A61F2002/30892 , A61F2002/30906 , A61F2002/30925 , A61F2002/3093 , A61F2002/30932 , A61F2002/30952 , A61F2002/3097 , A61F2002/3611 , A61F2002/3625 , A61F2230/0004 , A61F2230/0019 , A61F2230/0026 , A61F2250/0026 , A61F2250/0051 , A61F2310/00017 , A61F2310/00023 , A61F2310/00179 , A61F2310/00329 , A61F2310/00407 , A61F2310/00616 , A61F2310/00796 , A61F2310/00928 , A61F2310/00976 , A61F2310/00982 , A61L27/38 , A61L27/50 , A61L2400/18 , A61L2430/02 , A61L2430/12 , B23K26/06 , B23K26/066 , B23K2203/05 , B23K2203/14
摘要： An orthopedic implant includes an implant element for surgical insertion into a bone of a patient, the implant element having a microgeometric repetitive surface pattern in the form of alternating ridges and grooves, each having a fixed or established width in a range of about 2.0 to about 25 microns (micrometers) and a fixed or established depth in a range of about 2 to about 25 microns, in which the microgeometric repetitive patterns define a guide for preferential promotion of the rate, orientation and direction of growth colonies of cells of the bone which are in contact with the surface pattern.

9. 发明公开

EP1296612A2 DENTAL IMPLANT HAVING A DUAL BIO-AFFINITY COLLAR 有权转让
标题翻译：牙种植体双BIOAFFINITÄTSKRAGEN
公开(公告)号：EP1296612A2
公开(公告)日：2003-04-02
申请号：EP01983914.1
申请日：2001-06-19
申请人： BIOLOK International, Inc.
发明人： RICCI, John , ALEXANDER, Harold , NAIMAN, Charles (dec.),by Naiman, Harriet, Exec. , HOLLANDER, Bruce, L. , KOZAK, Ingo
IPC分类号： A61C8/00
CPC分类号： A61B17/68 , A61C8/0006 , A61C8/0012 , A61C8/0013 , A61C8/0018 , A61C2008/0046 , A61F2/30767 , A61F2/30771 , A61F2/3094 , A61F2/36 , A61F2/367 , A61F2/3672 , A61F2/3676 , A61F2/38 , A61F2/3804 , A61F2/40 , A61F2/4202 , A61F2/4241 , A61F2/468 , A61F2002/0086 , A61F2002/009 , A61F2002/30028 , A61F2002/30029 , A61F2002/30112 , A61F2002/30136 , A61F2002/30153 , A61F2002/30158 , A61F2002/30322 , A61F2002/30808 , A61F2002/30818 , A61F2002/3082 , A61F2002/30823 , A61F2002/30828 , A61F2002/30836 , A61F2002/30838 , A61F2002/30879 , A61F2002/30883 , A61F2002/30892 , A61F2002/30906 , A61F2002/30925 , A61F2002/3093 , A61F2002/30932 , A61F2002/30952 , A61F2002/3097 , A61F2002/3611 , A61F2002/3625 , A61F2230/0004 , A61F2230/0019 , A61F2230/0026 , A61F2250/0026 , A61F2250/0051 , A61F2310/00017 , A61F2310/00023 , A61F2310/00179 , A61F2310/00329 , A61F2310/00407 , A61F2310/00616 , A61F2310/00796 , A61F2310/00928 , A61F2310/00976 , A61F2310/00982 , A61L27/38 , A61L27/50 , A61L2400/18 , A61L2430/12 , B23K26/06 , B23K26/066 , B23K2203/04 , B23K2203/14
摘要： A dental implant (100) comprises a solid elongated body including a longitudinal axis having distal and proximal ends in which the proximal end includes a collar (120) having an axial length in a range of about 1 to about 3 millimeters. The collar exhibits a proximal (26) and a distal segment (28) in which the proximal segment includes a surface texture adapted for the promotion of osseo-integration of surrounding preferably cortical bone (14). Either one or the other of the sub-segments is provided with an ordered microgeometric repetitive surface pattern in the form of alternating ridges and grooves, each having a fixed or established width in a range of about 2.0 to about 25 microns and a fixed or established depth in a range of about 2.0 to about 25 microns, in which the microgeometric repetitive patterns define a guide for preferential promotion of the rate, orientation and direction of growth colonies of cells of the maxillofacial bone or tissue which is in contact with the surface pattern.

10. 发明公开

EP1006938A4 MULTIPLE INTERCONNECTED STENTS AND METHOD OF COATING STENTS 失效
标题翻译：多个相关的支架及方法涂层支架
公开(公告)号：EP1006938A4
公开(公告)日：2000-07-05
申请号：EP97921162
申请日：1997-04-04
申请人： IOWA INDIA INVESTMENTS COMPANY
发明人： JAYARAMAN SWAMINATHAN
IPC分类号： A61F2/00 , A61F2/07 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2/958 , B29C31/00 , B29C41/14 , B29C41/20 , A61F2/06
CPC分类号： B29C31/002 , A61F2/0077 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2/958 , A61F2002/072 , A61F2002/828 , A61F2002/91558 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2310/00982 , A61F2310/00994 , B29C41/14 , B29C41/20
摘要： Interconnected stents, coated microporous stents and method of coating are disclosed. The inventive stent (10) consists of a tubular member (11) interconnected to another tubular member (11) with a flexible member (25), each stent made from a flat sheet assembled together through a technique such as surface fusing. Preferably, the stent is made up of a plurality of spaced rows of slots with spaces between adjacent slots within a row staggered with respect to corresponding spaces on adjacent rows. In a first embodiment of a coated stent, a coating is attached to the stent only at a single area of line contact (130) on the outer surface of the stent with the remainder of the coating being larger than the unexpanded stent, but being made of dimensions designed to snugly receive the outer surfaces of the stent when it is expanded within a blood vessel.

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