发明公开
EP2173272A1 DOUBLE-STRUCTURED TISSUE IMPLANT AND A METHOD FOR PREPARATION AND USE THEREOF
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基本信息:
- 专利标题: DOUBLE-STRUCTURED TISSUE IMPLANT AND A METHOD FOR PREPARATION AND USE THEREOF
- 专利标题(中):双层结构的组织植入物及其制备方法和用途
- 申请号:EP08768602.8 申请日:2008-06-18
- 公开(公告)号:EP2173272A1 公开(公告)日:2010-04-14
- 发明人: CLAESSON, Hans, Peter , TARRANT, Laurence, J. B. , SMITH, Robert, Lane , SHORTKROFF, Sonya
- 申请人: Histogenics Corporation , Claesson, Hans Peter
- 申请人地址: 830 Winter Street, 3rd Floor Waltham, MA 02451 US
- 专利权人: Histogenics Corporation,Claesson, Hans Peter
- 当前专利权人: OCUGEN, INC.; US
- 当前专利权人地址: OCUGEN, INC.; US
- 代理机构: Sexton, Jane Helen
- 优先权: US958401P 20070703; US894124 20070820
- 国际公布: WO2009005596 20090108
- 主分类号: A61F2/00
- IPC分类号: A61F2/00
摘要:
A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit. A process for preparation of the double-structured implant or the stand alone secondary scaffold comprising lyophilization and dehydrothermal treatment.
摘要(中):
双重构造的组织植入物及其制备方法和用途用于植入到组织中的缺陷。 双重结构的组织植入物,其包括初级支架和次级支架由......组成结合有非离子型表面活性剂的可溶性胶原溶液和生成的主支架内定位。 一个独立的辅助支架植入物或单元。 一种用于制备双重结构的植入物的或独立的次级支架,其包含冻干和脱水热处理工艺。