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1. 发明授权

EP1653269B1 Microscope and method of preventing dew condensation on objective lens 有权
标题翻译：显微镜和方法，用于防止透镜上的冷凝
公开(公告)号：EP1653269B1
公开(公告)日：2009-09-09
申请号：EP05023507.6
申请日：2005-10-27
申请人： Olympus Corporation
发明人： Tsuchiya, Atsuhiro , Yamaguchi, Katsuyoshi , Kagayama, Akitsugu , Hasegawa, Kazuhiro , Endo, Hideaki , Koyama, Kenichi
IPC分类号： G02B27/00 , G02B21/30 , G02B7/00
CPC分类号： G02B27/0006 , C12M41/12 , C12M41/36 , G02B7/008 , G02B21/30
摘要： A microscope includes a high humidity space (21; 37) which is maintained at a predetermined gas temperature and a predetermined relative humidity for culture of a living sample (12); an objective lens (1) having a tip portion with a top lens (1a) which is disposed in the high humidity space (21; 37) and serving to allow for an observation of the living cell (12) incubated inside the high humidity space (21; 37); a heater (22; 33; 59) which heats the objective lens (1); and a temperature controller (25) which controls the heater so that a surface temperature and an internal temperature of the objective lens (1) are higher than a dew-point temperature and lower than a thermal death point of the living sample (12).

2. 发明授权

EP1762878B1 Observation apparatus and observation method 有权
标题翻译：观察装置和监控方法
公开(公告)号：EP1762878B1
公开(公告)日：2008-11-05
申请号：EP06018708.5
申请日：2006-09-06
申请人： Olympus Corporation
发明人： Endo, Hideaki , Kagayama, Akitsugu , Tsuchiya, Atsuhiro , Hasegawa, Kazuhiro
IPC分类号： G02B21/36
CPC分类号： G02B21/367

3. 发明授权

EP2078974B1 Microscope 有权
公开(公告)号：EP2078974B1
公开(公告)日：2013-10-09
申请号：EP09000049.8
申请日：2009-01-05
申请人： Olympus Corporation
发明人： Tsuchiya, Atsuhiro
IPC分类号： G02B21/00 , G02B21/08 , G02B21/14
CPC分类号： G02B21/14 , G02B21/0088 , G02B21/0092 , G02B21/086

4. 发明公开

EP1764640A2 Microscope for multipoint time-lapse imaging 审中-公开
标题翻译： MikroskopfürMehrpunkt - Zeitrafferaufnahmen
公开(公告)号：EP1764640A2
公开(公告)日：2007-03-21
申请号：EP06019198.8
申请日：2006-09-13
申请人： Olympus Corporation
发明人： Kagayama, Akitsugu , Tsuchiya, Atsuhiro , Endo, Hideaki , Hasegawa, Kazuhiro
IPC分类号： G02B21/36
CPC分类号： G02B21/367 , G01N21/6458
摘要： An observation apparatus includes an illumination unit (13, 15, 22 to 24, 31 to 34) that illuminates a specimen (S); an imaging unit (18) that captures an image of the specimen (S) to generate an observation image; and an imaging and display controller (51) that controls the imaging unit (18) so that an image of the specimen (S) is preliminary captured to generate a preliminary observation image, and controls a display unit (55) so that the preliminary observation image is,displayed. The apparatus also includes a storage controller (52) that stores, in a storage unit (58), a position selected based on the preliminary observation image and employed as a main observation position for a main observation of a partial region inside the specimen (S); and an illumination controller (52) that controls the illumination unit (13, 15, 22 to 24, 31 to 34) so that the specimen (S) is illuminated only in a time period during which the imaging unit (18) captures an image of the specimen (S), at least when the imaging unit (18) generates the preliminary observation image.
摘要翻译：观察装置包括：照射试样（S）的照明单元（13,15,22〜24,31〜34）。捕获所述检体（S）的图像以生成观察图像的成像单元（18）; 以及成像和显示控制器（51），其控制所述成像单元（18），使得初步捕获所述样本（S）的图像以产生初步观察图像，并且控制显示单元（55），使得所述初步观察显示图像。该装置还包括存储控制器（52），其存储在存储单元（58）中的基于初步观察图像所选择的位置，并作为主要观察位置用于主要观察样本内的部分区域（S ）; 以及照明控制器（52），其控制所述照明单元（13,15,22〜24,31〜34），使得所述检体（S）仅在所述摄像单元（18）拍摄图像的时间段内被照明至少当成像单元（18）产生初步观察图像时，该样本（S）。

5. 发明授权

EP1582904B1 System microscope 有权
标题翻译：显微镜系统
公开(公告)号：EP1582904B1
公开(公告)日：2008-06-25
申请号：EP05005645.6
申请日：2005-03-15
申请人： Olympus Corporation
发明人： Aono, Yasushi , Nakata, Tatsuo , Tsuchiya, Atsuhiro
IPC分类号： G02B21/00 , G02B21/24 , G02B21/18 , G03F7/20
CPC分类号： G02B21/0088 , G02B21/06 , G02B21/248

6. 发明公开

EP1764640A3 Microscope for multipoint time-lapse imaging 审中-公开
标题翻译：镜下为多 - 间隔摄影
公开(公告)号：EP1764640A3
公开(公告)日：2007-04-18
申请号：EP06019198.8
申请日：2006-09-13
申请人： Olympus Corporation
发明人： Kagayama, Akitsugu , Tsuchiya, Atsuhiro , Endo, Hideaki , Hasegawa, Kazuhiro
IPC分类号： G02B21/36
CPC分类号： G02B21/367 , G01N21/6458
摘要： An observation apparatus includes an illumination unit (13, 15, 22 to 24, 31 to 34) that illuminates a specimen (S); an imaging unit (18) that captures an image of the specimen (S) to generate an observation image; and an imaging and display controller (51) that controls the imaging unit (18) so that an image of the specimen (S) is preliminary captured to generate a preliminary observation image, and controls a display unit (55) so that the preliminary observation image is,displayed. The apparatus also includes a storage controller (52) that stores, in a storage unit (58), a position selected based on the preliminary observation image and employed as a main observation position for a main observation of a partial region inside the specimen (S); and an illumination controller (52) that controls the illumination unit (13, 15, 22 to 24, 31 to 34) so that the specimen (S) is illuminated only in a time period during which the imaging unit (18) captures an image of the specimen (S), at least when the imaging unit (18) generates the preliminary observation image.

7. 发明公开

EP1653269A1 Microscope and method of preventing dew condensation on objective lens 有权
标题翻译： Mikroskop und Verfahren zur Verhinderung von Kondensation am Objektiv
公开(公告)号：EP1653269A1
公开(公告)日：2006-05-03
申请号：EP05023507.6
申请日：2005-10-27
申请人： Olympus Corporation
发明人： Tsuchiya, Atsuhiro , Yamaguchi, Katsuyoshi , Kagayama, Akitsugu , Hasegawa, Kazuhiro , Endo, Hideaki , Koyama, Kenichi
IPC分类号： G02B27/00 , G02B21/30 , G02B7/00
CPC分类号： G02B27/0006 , C12M41/12 , C12M41/36 , G02B7/008 , G02B21/30
摘要： A microscope includes a high humidity space (21; 37) which is maintained at a predetermined gas temperature and a predetermined relative humidity for culture of a living sample (12); an objective lens (1) having a tip portion with a top lens (1a) which is disposed in the high humidity space (21; 37) and serving to allow for an observation of the living cell (12) incubated inside the high humidity space (21; 37); a heater (22; 33; 59) which heats the objective lens (1); and a temperature controller (25) which controls the heater so that a surface temperature and an internal temperature of the objective lens (1) are higher than a dew-point temperature and lower than a thermal death point of the living sample (12).
摘要翻译：显微镜包括保持在预定气体温度和预定相对湿度以用于培养活体样品（12）的高湿度空间（21; 37）; 物镜（1），其具有顶部，所述顶部具有顶部透镜（1a），所述顶部透镜（1a）设置在所述高湿度空间（21; 37）中，并且用于允许观察在高湿度空间内孵育的活细胞（12）（21; 37）; 加热物镜（1）的加热器（22; 33; 59）。以及温度控制器（25），其控制所述加热器，使得所述物镜（1）的表面温度和内部温度高于露点温度并且低于所述活体样品（12）的热死亡点。

8. 发明公开

EP1602960A1 Microscope 审中-公开
标题翻译：显微镜
公开(公告)号：EP1602960A1
公开(公告)日：2005-12-07
申请号：EP05011694.6
申请日：2005-05-31
申请人： Olympus Corporation
发明人： Tsuchiya, Atsuhiro , Hasegawa, Kazuhiro
IPC分类号： G02B21/06 , G01N21/64
CPC分类号： G02B21/16 , G01N21/6458 , G01N2021/6484 , G02B21/0096 , G02B21/361
摘要： A fluorescence microscope (101) includes an objective lens (103), light projecting unit (105), and CCD camera (122). The light projecting unit (105) is provided with a rear converter (109), wavelength multiplexing device (110), first light source unit (111), and second light source unit (115). Both a first light-emitting diode (112) of the first light source unit (111) and a second light-emitting diode (116) of the second light source unit (115) are in a positional relationship conjugate to the rear focus of the objective lens (103). A photometric device is placed on the opposite side of the objective lens (103) to a specimen (121). The photometric device includes a pinhole (126) and photodiode (127). A power supply device (119) controls driving currents for the first light-emitting diode (112) and second light-emitting diode (116) on the basis of the photometric value obtained from the photodiode (127).
摘要翻译：荧光显微镜（101）包括物镜（103），投光部（105）和CCD照相机（122）。光投射单元105设置有后转换器109，波长多路复用装置110，第一光源单元111和第二光源单元115。第一光源单元（111）的第一发光二极管（112）和第二光源单元（115）的第二发光二极管（116）两者的位置关系与物镜（103）。将测光装置放置在物镜（103）的与样品（121）相对的一侧上。测光装置包括针孔（126）和光电二极管（127）。基于从光电二极管（127）获得的光度值，电源装置（119）控制第一发光二极管（112）和第二发光二极管（116）的驱动电流。

9. 发明授权

EP1602960B1 Microscope 有权
公开(公告)号：EP1602960B1
公开(公告)日：2018-10-24
申请号：EP05011694.6
申请日：2005-05-31
申请人： Olympus Corporation
发明人： Tsuchiya, Atsuhiro , Hasegawa, Kazuhiro
IPC分类号： G02B21/06 , G01N21/64
CPC分类号： G02B21/16 , G01N21/6458 , G01N2021/6484 , G02B21/0096 , G02B21/361
摘要： A fluorescence microscope (101) includes an objective lens (103), light projecting unit (105), and CCD camera (122). The light projecting unit (105) is provided with a rear converter (109), wavelength multiplexing device (110), first light source unit (111), and second light source unit (115). Both a first light-emitting diode (112) of the first light source unit (111) and a second light-emitting diode (116) of the second light source unit (115) are in a positional relationship conjugate to the rear focus of the objective lens (103). A photometric device is placed on the opposite side of the objective lens (103) to a specimen (121). The photometric device includes a pinhole (126) and photodiode (127). A power supply device (119) controls driving currents for the first light-emitting diode (112) and second light-emitting diode (116) on the basis of the photometric value obtained from the photodiode (127).

10. 发明授权

EP1677136B1 Culture observation apparatus 有权
标题翻译：细胞培养监控设备
公开(公告)号：EP1677136B1
公开(公告)日：2008-02-13
申请号：EP05028519.6
申请日：2005-12-27
申请人： Olympus Corporation
发明人： Tsuchiya, Atsuhiro , Hirano, Ryuichi , Endo, Hideaki , Koyama, Kenichi , Hasegawa, Kazuhiro , Kagayama, Akitsugu , Yamaguchi, Katsuyoshi
IPC分类号： G02B27/00 , G02B21/00 , G02B21/24 , G02B21/02 , C12M1/00
CPC分类号： C12M41/36 , C12M41/14 , G02B7/22 , G02B21/0088 , G02B21/02

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