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1. 发明公开

EP1764640A2 Microscope for multipoint time-lapse imaging 审中-公开
标题翻译： MikroskopfürMehrpunkt - Zeitrafferaufnahmen
公开(公告)号：EP1764640A2
公开(公告)日：2007-03-21
申请号：EP06019198.8
申请日：2006-09-13
申请人： Olympus Corporation
发明人： Kagayama, Akitsugu , Tsuchiya, Atsuhiro , Endo, Hideaki , Hasegawa, Kazuhiro
IPC分类号： G02B21/36
CPC分类号： G02B21/367 , G01N21/6458
摘要： An observation apparatus includes an illumination unit (13, 15, 22 to 24, 31 to 34) that illuminates a specimen (S); an imaging unit (18) that captures an image of the specimen (S) to generate an observation image; and an imaging and display controller (51) that controls the imaging unit (18) so that an image of the specimen (S) is preliminary captured to generate a preliminary observation image, and controls a display unit (55) so that the preliminary observation image is,displayed. The apparatus also includes a storage controller (52) that stores, in a storage unit (58), a position selected based on the preliminary observation image and employed as a main observation position for a main observation of a partial region inside the specimen (S); and an illumination controller (52) that controls the illumination unit (13, 15, 22 to 24, 31 to 34) so that the specimen (S) is illuminated only in a time period during which the imaging unit (18) captures an image of the specimen (S), at least when the imaging unit (18) generates the preliminary observation image.
摘要翻译：观察装置包括：照射试样（S）的照明单元（13,15,22〜24,31〜34）。捕获所述检体（S）的图像以生成观察图像的成像单元（18）; 以及成像和显示控制器（51），其控制所述成像单元（18），使得初步捕获所述样本（S）的图像以产生初步观察图像，并且控制显示单元（55），使得所述初步观察显示图像。该装置还包括存储控制器（52），其存储在存储单元（58）中的基于初步观察图像所选择的位置，并作为主要观察位置用于主要观察样本内的部分区域（S ）; 以及照明控制器（52），其控制所述照明单元（13,15,22〜24,31〜34），使得所述检体（S）仅在所述摄像单元（18）拍摄图像的时间段内被照明至少当成像单元（18）产生初步观察图像时，该样本（S）。

2. 发明公开

EP1553436A1 Fluorescence microscope with LED light source and controller unit for synchronizing imaging and switching the light source on and off 有权
标题翻译：荧光显微镜与LED光源和控制单元，用于同步所述图像与和关闭光源的切换记录
公开(公告)号：EP1553436A1
公开(公告)日：2005-07-13
申请号：EP04030679.7
申请日：2004-12-23
申请人： Olympus Corporation
发明人： Endo, Hideaki
IPC分类号： G02B21/16
CPC分类号： G02B21/16
摘要： A fluorescence microscope is characterized by comprising a light source (4) having a light emitting diode as light source, an illumination optical system (4,5,6,7) which leads light from the light source (4) onto a specimen, an observation optical system (3,7,8,9,10) to which fluorescence emitted from the specimen is led, an imager (11) which images the fluorescence led to the observation optical system, and a controller (16) which controls lighting/light out of the light emitting diode (4) synchronously with imaging timing of the imager.
摘要翻译：的荧光显微镜是通过包括（4），其具有发光二极管作为光源，以照明光学系统（4,5,6,7）从所述光源（4）到试样导致光的光源为特征的观察光学系统（3,7,8,9,10），以从所述样品发出的荧光哪个被引导，在成像器（11），该图像中的荧光引导到观察光学系统，和一个控制器（16），其控制照明/ 光出光的发光二极管（4）同步地与成像器的成像定时的。

3. 发明授权

EP1677136B1 Culture observation apparatus 有权
标题翻译：细胞培养监控设备
公开(公告)号：EP1677136B1
公开(公告)日：2008-02-13
申请号：EP05028519.6
申请日：2005-12-27
申请人： Olympus Corporation
发明人： Tsuchiya, Atsuhiro , Hirano, Ryuichi , Endo, Hideaki , Koyama, Kenichi , Hasegawa, Kazuhiro , Kagayama, Akitsugu , Yamaguchi, Katsuyoshi
IPC分类号： G02B27/00 , G02B21/00 , G02B21/24 , G02B21/02 , C12M1/00
CPC分类号： C12M41/36 , C12M41/14 , G02B7/22 , G02B21/0088 , G02B21/02

4. 发明公开

EP1768065A1 Multipoint time-lapse imaging with irradiation dose control 审中-公开
标题翻译：多部门Mehrpunkt-Bildaufnahme mit Kontrolle der Beleuchtungsdosis
公开(公告)号：EP1768065A1
公开(公告)日：2007-03-28
申请号：EP06019681.3
申请日：2006-09-20
申请人： Olympus Corporation
发明人： Hasegawa, Kazuhiro , Tsuchiya, Atsuhiro , Endo, Hideaki , Kagayama, Akitsugu
IPC分类号： G06T7/00 , G02B21/36
CPC分类号： G02B21/367 , G06T7/0012 , G06T2207/30024
摘要： An observation apparatus includes an illuminating unit (13, 15, 22 to 24, 31 to 34) that illuminates a sample (S); an imaging unit (18) that captures an image of the sample (S) to generate an observation image; a storage unit (58) that stores the observation image in association with an illumination condition of the illuminating unit (13, 15, 22 to 24, 31 to 34) at generation of the observation image by the imaging unit (18); an imaging controller (51) that controls the imaging unit (18) to capture the image of the sample (S) to generate the observation image and stores the observation image in the storage unit (58); and an illumination controller (52) that controls the illuminating unit (13, 15, 22 to 24, 31 to 34) to illuminate the sample (S), and stores the illumination condition in the storage unit (58) every time the imaging unit (18) captures the image of the sample (S).
摘要翻译：观察装置包括照射样品（S）的照明单元（13,15,22〜24,31〜34）。捕获所述样本（S）的图像以生成观察图像的成像单元（18）; 存储单元（58），其在通过所述摄像单元（18）生成观察图像时，与所述照明单元（13,15,22〜24,31〜34）的照明条件相关联地存储所述观察图像。成像控制器（51），其控制所述成像单元（18）捕获所述样本（S）的图像以生成所述观察图像，并将所述观察图像存储在所述存储单元（58）中; 以及照明控制器（52），其控制所述照明单元（13,15,22〜24,31〜34）照射所述样本（S），并且每当所述摄像单元（S）成像时，将所述照明条件存储在所述存储单元（18）捕获样品（S）的图像。

5. 发明公开

EP1762878A1 Observation apparatus and observation method 有权
标题翻译： Beobachtungsvorrichtung und Beobachtungsverfahren
公开(公告)号：EP1762878A1
公开(公告)日：2007-03-14
申请号：EP06018708.5
申请日：2006-09-06
申请人： Olympus Corporation
发明人： Endo, Hideaki , Kagayama, Akitsugu , Tsuchiya, Atsuhiro , Hasegawa, Kazuhiro
IPC分类号： G02B21/36
CPC分类号： G02B21/367
摘要： An observation apparatus includes an incident-light illumination optical system, a transmitting illumination optical system, an imaging unit (18), an input device (56), a storage unit (58), an imaging controller (51), a microscope controller (52), and an imaging information management unit (54). The imaging information management unit (54) compares an area position, of an imaging area of the imaging unit (18), indicated by position information input from the input device (56) with an area position stored in the storage unit (58) to determine whether the area position indicated by the position information is stored in the storage unit (58). When the area position is not stored in the storage unit (58), the imaging controller (51) controls the imaging unit (18) to image the specimen (S) and to generate an observation image, and stores the observation image in the storage unit (58). The microscope controller (52) controls one of the optical systems to illuminate the specimen (S) only during an imaging period, when the imaging unit (18) images the specimen (S).
摘要翻译：观察装置包括入射光照明光学系统，透射照明光学系统，成像单元（18），输入装置（56），存储单元（58），成像控制器（51），显微镜控制器 52）和成像信息管理单元（54）。成像信息管理单元（54）将从输入装置（56）输入的位置信息所指示的摄像单元（18）的摄像区域的区域位置与存储在存储单元（58）中的区域位置确定由位置信息指示的区域位置是否存储在存储单元（58）中。当区域位置未存储在存储单元（58）中时，成像控制器（51）控制成像单元（18）对样本（S）成像并产生观察图像，并将观察图像存储在存储单元单位（58）。显微镜控制器（52）仅在成像单元（18）对样本（S）进行成像时，在成像期间控制光学系统之一照射样本（S）。

6. 发明授权

EP1691230B1 Photo-micrographing device and its control method 有权转让
标题翻译：照相显微照相装置及其控制方法
公开(公告)号：EP1691230B1
公开(公告)日：2017-03-01
申请号：EP06000622.8
申请日：2006-01-12
申请人： Olympus Corporation
发明人： Endo, Hideaki , Kagayama, Akitsugu , Yamaguchi, Katsuyoshi
IPC分类号： G02B21/36 , G02B21/26
CPC分类号： G02B21/367 , G02B21/26
摘要： By comprising a microscope, means for obtaining an inspection object image, means for setting the view field of the microscope, and storing the position information of a stage corresponding to the view field, means for storing setting information of the microscope and camera unit in the view field, means for storing shooting conditions in the case where time-lapse shooting is applied to the view field, means for obtaining a time-lapse shooting image for each view field, based on the stored position information, setting information stored and shooting conditions and means for collectively displaying the latest taken time-lapse shooting images for each view field, a Photo-micrographing device and its control method capable of shooting each inspection obj ect without being restricted by a shooting waiting time and the like when applying multi-point time-lapse shooting to a plurality of shooting ranges can be provided.
摘要翻译：通过包括显微镜，用于获得检查对象图像的装置，用于设置显微镜的视场的装置以及存储与视场对应的台的位置信息的装置，用于将显微镜和照相机单元的设置信息存储在用于存储在对视场进行延时拍摄的情况下的拍摄条件的装置，用于基于存储的位置信息，所存储的设置信息和拍摄条件来获得每个视场的延时拍摄图像的装置以及用于集中显示每个视场的最新拍摄的时间推移拍摄图像的装置，当应用多点时，能够拍摄每个检查对象而不受拍摄等待时间等的限制的拍照显微装置及其控制方法可以提供到多个拍摄范围的延时拍摄。

7. 发明授权

EP1653269B1 Microscope and method of preventing dew condensation on objective lens 有权
标题翻译：显微镜和方法，用于防止透镜上的冷凝
公开(公告)号：EP1653269B1
公开(公告)日：2009-09-09
申请号：EP05023507.6
申请日：2005-10-27
申请人： Olympus Corporation
发明人： Tsuchiya, Atsuhiro , Yamaguchi, Katsuyoshi , Kagayama, Akitsugu , Hasegawa, Kazuhiro , Endo, Hideaki , Koyama, Kenichi
IPC分类号： G02B27/00 , G02B21/30 , G02B7/00
CPC分类号： G02B27/0006 , C12M41/12 , C12M41/36 , G02B7/008 , G02B21/30
摘要： A microscope includes a high humidity space (21; 37) which is maintained at a predetermined gas temperature and a predetermined relative humidity for culture of a living sample (12); an objective lens (1) having a tip portion with a top lens (1a) which is disposed in the high humidity space (21; 37) and serving to allow for an observation of the living cell (12) incubated inside the high humidity space (21; 37); a heater (22; 33; 59) which heats the objective lens (1); and a temperature controller (25) which controls the heater so that a surface temperature and an internal temperature of the objective lens (1) are higher than a dew-point temperature and lower than a thermal death point of the living sample (12).

8. 发明授权

EP1762878B1 Observation apparatus and observation method 有权
标题翻译：观察装置和监控方法
公开(公告)号：EP1762878B1
公开(公告)日：2008-11-05
申请号：EP06018708.5
申请日：2006-09-06
申请人： Olympus Corporation
发明人： Endo, Hideaki , Kagayama, Akitsugu , Tsuchiya, Atsuhiro , Hasegawa, Kazuhiro
IPC分类号： G02B21/36
CPC分类号： G02B21/367

9. 发明公开

EP1764640A3 Microscope for multipoint time-lapse imaging 审中-公开
标题翻译：镜下为多 - 间隔摄影
公开(公告)号：EP1764640A3
公开(公告)日：2007-04-18
申请号：EP06019198.8
申请日：2006-09-13
申请人： Olympus Corporation
发明人： Kagayama, Akitsugu , Tsuchiya, Atsuhiro , Endo, Hideaki , Hasegawa, Kazuhiro
IPC分类号： G02B21/36
CPC分类号： G02B21/367 , G01N21/6458
摘要： An observation apparatus includes an illumination unit (13, 15, 22 to 24, 31 to 34) that illuminates a specimen (S); an imaging unit (18) that captures an image of the specimen (S) to generate an observation image; and an imaging and display controller (51) that controls the imaging unit (18) so that an image of the specimen (S) is preliminary captured to generate a preliminary observation image, and controls a display unit (55) so that the preliminary observation image is,displayed. The apparatus also includes a storage controller (52) that stores, in a storage unit (58), a position selected based on the preliminary observation image and employed as a main observation position for a main observation of a partial region inside the specimen (S); and an illumination controller (52) that controls the illumination unit (13, 15, 22 to 24, 31 to 34) so that the specimen (S) is illuminated only in a time period during which the imaging unit (18) captures an image of the specimen (S), at least when the imaging unit (18) generates the preliminary observation image.

10. 发明授权

EP1553436B1 Fluorescence microscope with LED light source and controller unit for synchronizing imaging and switching the light source on and off 有权
标题翻译：荧光显微镜与LED光源和控制单元，用于同步所述图像与和关闭光源的切换记录
公开(公告)号：EP1553436B1
公开(公告)日：2006-12-06
申请号：EP04030679.7
申请日：2004-12-23
申请人： Olympus Corporation
发明人： Endo, Hideaki
IPC分类号： G02B21/16
CPC分类号： G02B21/16

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