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1. 发明公开

EP0098392A3 Filtration membrane and process for producing the membrane 有权转让
标题翻译：过滤膜和生产膜的方法
公开(公告)号：EP0098392A3
公开(公告)日：1984-03-07
申请号：EP83105534
申请日：1983-06-06
申请人： GAMBRO DIALYSATOREN K.G. , Gambro Lundia AB
发明人： Göhl, Hermann Joseph , Geiling, Günther Friedrich , Mayer, Georg Bernhard , Gullberg, Claes-Ake
IPC分类号： B01D13/04 , A61M01/03
CPC分类号： D01D5/24 , B01D69/02 , B01D69/08 , B01D71/56
摘要： Filtration membrane, especially adapted for use in hemofiltration as well as filtration of infusion solutions. The membrane, preferably in the form of a hollow fiber, is made of a polymer which is soluble in a polar, non-protonic organic solvent. The most preferred polymer for the membrane material is polyamide. Characterizing for the membrane is high ultrafiltration rates (permeabilities to water) of up to 500 x 10- 4 ml/sec. x cm2 x atm., and impermeability to albumin (M w 68,000). The membrane is prepared by extruding a polymer solution with a center liquid under conditions such that the volume of polymer solution to volume of center liquid ratio is within the range of from 2 : 1 to 4 : 1. Simultaneously, the inner diameter to wall thickness ratio of the hollow fiber is preferably correlated to the polymer concentration and is set to 150:75 to 280:75 at a polymer concentration of 5-20%. The most preferred such correlation is 220 : 75 at a polymer concentration of 11 %.

2. 发明授权

EP0098392B1 Filtration membrane and process for producing the membrane 有权转让
标题翻译：过滤膜和生产膜的方法
公开(公告)号：EP0098392B1
公开(公告)日：1987-12-09
申请号：EP83105534.8
申请日：1983-06-06
申请人： Gambro Dialysatoren GmbH & Co. KG , Gambro Lundia AB
发明人： Göhl, Hermann Joseph , Geiling, Günther Friedrich , Mayer, Georg Bernhard , Gullberg, Claes-Ake
IPC分类号： B01D13/04 , A61M1/34
CPC分类号： D01D5/24 , B01D69/02 , B01D69/08 , B01D71/56

3. 发明公开

EP0098392A2 Filtration membrane and process for producing the membrane 有权转让
标题翻译： Membran und Verfahren zu ihrer Herstellung。
公开(公告)号：EP0098392A2
公开(公告)日：1984-01-18
申请号：EP83105534.8
申请日：1983-06-06
申请人： Gambro Dialysatoren GmbH & Co. KG , Gambro Lundia AB
发明人： Göhl, Hermann Joseph , Geiling, Günther Friedrich , Mayer, Georg Bernhard , Gullberg, Claes-Ake
IPC分类号： B01D13/04 , A61M1/34
CPC分类号： D01D5/24 , B01D69/02 , B01D69/08 , B01D71/56
摘要： Filtration membrane, especially adapted for use in hemofiltration as well as filtration of infusion solutions.
The membrane, preferably in the form of a hollow fiber, is made of a polymer which is soluble in a polar, non-protonic organic solvent. The most preferred polymer for the membrane material is polyamide. Characterizing for the membrane is high ultrafiltration rates (permeabilities to water) of up to 500 x 10- 4 ml/sec. x cm2 x atm., and impermeability to albumin (M w 68,000).
The membrane is prepared by extruding a polymer solution with a center liquid under conditions such that the volume of polymer solution to volume of center liquid ratio is within the range of from 2 : 1 to 4 : 1. Simultaneously, the inner diameter to wall thickness ratio of the hollow fiber is preferably correlated to the polymer concentration and is set to 150:75 to 280:75 at a polymer concentration of 5-20%. The most preferred such correlation is 220 : 75 at a polymer concentration of 11 %.
摘要翻译：过滤膜，特别适用于血液滤过以及过滤输液。优选为中空纤维形式的膜由可溶于极性非质子有机溶剂的聚合物制成。用于膜材料的最优选的聚合物是聚酰胺。膜的特征在于高达500×10 -4毫升/秒的超滤速率（渗透水）。 x cm 2 x大气压和对白蛋白的不渗透性（Mw 68,000）。 ...通过在聚合物溶液体积与中心液体积比为2:1至4:1的条件下将中心液挤出聚合物溶液制备膜。同时，中空纤维的内径与壁厚比优选与聚合物浓度相关，并且在聚合物浓度为5-20％时设定为150:75至280:75。在聚合物浓度为11％时，最优选的相关性为220:75。

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