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1. 发明授权

EP2542282B1 INJECTION DEVICE 有权转让
公开(公告)号：EP2542282B1
公开(公告)日：2017-11-15
申请号：EP11750109.8
申请日：2011-02-28
申请人： Duoject Medical Systems Inc.
发明人： REYNOLDS, David, L. , MACDONALD, Daniel , TREMBLAY, Yan , TREPANIER, Julie
IPC分类号： A61M5/32 , A61M5/31 , A61M5/24
CPC分类号： A61M5/3202 , A61M5/2466 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M5/3293 , A61M2005/2414 , A61M2005/247 , A61M2005/3267 , A61M2005/3289

2. 发明公开

EP2717946A1 INJECTION DEVICE 失效
标题翻译：注射装置
公开(公告)号：EP2717946A1
公开(公告)日：2014-04-16
申请号：EP12796675.2
申请日：2012-06-01
申请人： Duoject Medical Systems Inc.
发明人： REYNOLDS, David L. , MACDONALD, Daniel , TREMBLAY, Yan , TREPANIER, Julie
IPC分类号： A61M5/24 , A61M5/32
CPC分类号： A61M5/3294 , A61M5/1782 , A61M5/19 , A61M5/2448 , A61M5/2466 , A61M5/31511 , A61M5/3202 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M5/3293 , A61M5/3298 , A61M2005/2407 , A61M2005/2414 , A61M2005/247 , A61M2005/3267 , A61M2005/3289
摘要： An injection device which includes a housing (12), a needle hub (38) slidable within the housing (12), a needle (40) having a distal end piercing tip (42) and a proximal end piercing tip (44), the needle hub (40) being moveable from a first position wherein the distal piercing tip (42) is within the housing to a second position wherein the distal end piercing tip (42) extends outwardly of housing (12), a first spring (23) biasing the needle hub (38) towards the first position, and a cartridge receiving member (48) mounted within the housing, and a plunger rod assembly (166), the plunger rod assembly (166) having a distal interior chamber (102) and a proximal interior chamber (103), the distal interior chamber (102) being designed to receive a cartridge (85) containing a liquid (89), the cartridge having a septum (87) and a plunger (88) to prevent exit of the liquid, and a second needle hub (91) located in the proximal chamber, a second hollow needle (92) mounted in the second needle hub, the second hollow needle having a distal piercing tip (94) and a proximal piercing tip (93), the second hollow needle being moveable from a first non piercing position to a second position whereby said distal piercing tip (94) will pierce the septum (87).
摘要翻译：本发明公开了一种注射装置，该注射装置包括壳体（12），可在壳体（12）内滑动的针座（38），具有远端穿刺尖端（42）和近端穿刺尖端（44）的针（40）所述针座（40）可从所述远端刺穿尖端（42）在所述壳体内的第一位置移动到所述远端刺穿尖端（42）向所述壳体（12）外部延伸的第二位置，第一弹簧（23）（38）朝向第一位置偏置，以及安装在壳体内的药筒接收构件（48）和柱塞杆组件（166），柱塞杆组件（166）具有远端内腔室（102）和（103），所述远端内部腔室（102）被设计成接收包含液体（89）的药筒（85），所述药筒具有隔膜（87）和柱塞（88）以防止液体以及位于近端腔室中的第二针座（91），第二针状体（92）安装在第二针状体中 b，第二中空针具有远侧刺穿末端94和近侧刺穿末端93，第二中空针可从第一非刺穿位置移动到第二位置，由此所述远侧刺穿末端94将刺穿隔膜（87）。

3. 发明公开

EP2542282A1 INJECTION DEVICE 有权转让
标题翻译：注射装置
公开(公告)号：EP2542282A1
公开(公告)日：2013-01-09
申请号：EP11750109.8
申请日：2011-02-28
申请人： DUOJECT MEDICAL SYSTEMS INC
发明人： REYNOLDS, David, L. , MACDONALD, Daniel , TREMBLAY, Yan , TREPANIER, Julie
IPC分类号： A61M5/32 , A61M5/31
CPC分类号： A61M5/3202 , A61M5/2466 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M5/3293 , A61M2005/2414 , A61M2005/247 , A61M2005/3267 , A61M2005/3289
摘要： An injection device (10) comprising a housing (12), a needle hub (38) slidable within the housing (12), a needle (40) having a distal end piercing tip (42) and a proximal end piercing tip (44), the needle hub being moveable from a first position wherein the distal end piercing tip (42) is within the housing to a second position wherein the distal end piercing tip (42) extends outwardly of the housing (12), a spring (23) biasing the needle hub (38) towards the first position, and a cartridge receiving member (48) mounted within the housing (12), and a plunger rod assembly (66) for exerting pressure on the cartridge receiving member (48) to move the cartridge (26) and the needle hub (38) from the first position to the second position, the plunger rod assembly (66) and the cartridge receiving member (48) being arranged such that when the cartridge rod assembly is pushed, a rotational movement is imparted to the cartridge receiving member (48) to thereby prevent access to the cartridge after injection.
摘要翻译：一种包括壳体（12），可在壳体（12）内滑动的针座（38），具有远端穿刺尖端（42）和近端穿刺尖端（44）的针（40）的注射装置（10）所述针座能够从所述远端刺穿末端（42）在所述外壳内的第一位置移动到所述远端刺穿末端（42）向所述外壳（12）的外部延伸的第二位置，弹簧（23）（38）朝向第一位置偏置，以及安装在壳体（12）内的药筒接收构件（48），以及柱塞杆组件（66），用于在药筒接收构件（48）上施加压力以移动（26）和针座（38）从第一位置移动到第二位置时，柱塞杆组件（66）和药筒接收构件（48）被布置成使得当药筒杆组件被推动时，旋转运动传给盒容纳部件（48），从而防止进入盒后部呃注射。

4. 发明授权

EP2475454B1 EASY-LINK DEVICE FOR FLUID TRANSFER 有权
标题翻译：轻松地为流体输送设备连接
公开(公告)号：EP2475454B1
公开(公告)日：2015-11-11
申请号：EP10814841.2
申请日：2010-09-08
申请人： DUOJECT MEDICAL SYSTEMS INC
发明人： MACDONALD, Daniel , RAYMOND, Steven , REYNOLDS, David, L.
IPC分类号： B01F5/04 , A61J1/20 , B01L3/00
CPC分类号： A61J1/2096 , A61J1/1425 , A61J1/201 , A61J1/2051 , B01F13/002 , B01F13/0022 , B01F15/0212 , B01F15/0223

5. 发明授权

EP2296797B1 RACK AND PINION DRIVE FOR BY-PASS CARTRIDGE 有权
标题翻译：齿条旁路盒
公开(公告)号：EP2296797B1
公开(公告)日：2014-09-17
申请号：EP09761205.5
申请日：2009-06-10
申请人： DUOJECT MEDICAL SYSTEMS INC
发明人： REYNOLDS, David L. , MACDONALD, Daniel , McCARTHY, Roger
IPC分类号： B01F15/02 , B01F15/00 , B01F13/00 , A61M5/24
CPC分类号： B01F15/0201 , A61M5/2448 , A61M2005/3152 , B01F13/002 , B01F13/0023 , B01F15/0087 , B01F15/0237

6. 发明授权

EP2109435B1 AIRLESS MIXING WITH A BY-PASS SYRINGE 有权
标题翻译：带有旁通将注射器空气LOOSE合剂
公开(公告)号：EP2109435B1
公开(公告)日：2014-05-07
申请号：EP08706270.9
申请日：2008-01-21
申请人： Duoject Medical Systems, Inc.
发明人： REYNOLDS, David, L. , MACDONALD, Daniel , McCARTHY, Roger
IPC分类号： A61M5/31 , A61J1/20 , A61M5/38
CPC分类号： A61M5/385 , A61J1/201 , A61J1/2055 , A61J1/2096

7. 发明公开

EP2475454A1 EASY-LINK DEVICE FOR FLUID TRANSFER 有权
标题翻译：轻松地为流体输送设备连接
公开(公告)号：EP2475454A1
公开(公告)日：2012-07-18
申请号：EP10814841.2
申请日：2010-09-08
申请人： DUOJECT MEDICAL SYSTEMS INC
发明人： MACDONALD, Daniel , RAYMOND, Steven , REYNOLDS, David, L.
IPC分类号： B01F5/04 , A61J1/20 , B01L3/00
CPC分类号： A61J1/2096 , A61J1/1425 , A61J1/201 , A61J1/2051 , B01F13/002 , B01F13/0022 , B01F15/0212 , B01F15/0223
摘要： A transfer device (10) which comprises an outer housing (24), an inner body (26) formed within the housing (24), the inner body (26) having a conduit (66) extending therethrough to provide fluid communication between upper and lower chambers, the conduit (66) having a piercing tip (68) at a lower end, a cap (54)having a top wall and a downwardly extending wall (58), the cap being retained in position such that access cannot be had to the inner body (26), and a pushing member (44) which has at least one leg (48) extending upwardly, the pushing member having an activated position where the leg (48) will extend upwardly to the upper chamber and move the cap (54) such that access may be had to the inner body (26).

8. 发明公开

EP2493546A1 DEVICE AND METHOD FOR TOPICAL APPLICATION OF THERAPEUTICS OR COSMETIC COMPOSITIONS 审中-公开
标题翻译：设备和方法治疗或美容组合物的局部应用
公开(公告)号：EP2493546A1
公开(公告)日：2012-09-05
申请号：EP10827369.9
申请日：2010-10-25
申请人： Revance Therapeutics, Inc. , Duoject Medical Systems, Inc.
发明人： RUEGG, Curtis L. , REYNOLDS, David L. , MACDONALD, Daniel , TREMBLAY, Yan
IPC分类号： A61M35/00
CPC分类号： A45D34/04 , A45D2200/058 , A61J1/201 , A61J1/2013 , A61J1/2065 , A61J1/2089 , A61J1/2096 , A61K8/64 , A61K8/90 , A61K8/99 , A61Q19/00 , A61Q19/08
摘要： This invention relates to devices and methods for safely reconstituting and administering topical therapeutic or cosmetic compositions. The topical applicator according to the invention is particularly well suited for storing, reconstituting, and administering or applying highly toxic substances.

9. 发明公开

EP2296797A1 RACK AND PINION DRIVE FOR BY-PASS CARTRIDGE 有权
标题翻译：齿条旁路盒
公开(公告)号：EP2296797A1
公开(公告)日：2011-03-23
申请号：EP09761205.5
申请日：2009-06-10
申请人： DUOJECT MEDICAL SYSTEMS INC
发明人： REYNOLDS, David L. , MACDONALD, Daniel , McCARTHY, Roger
IPC分类号： B01F15/02 , A61J1/20 , B01F3/12
CPC分类号： B01F15/0201 , A61M5/2448 , A61M2005/3152 , B01F13/002 , B01F13/0023 , B01F15/0087 , B01F15/0237
摘要： A device for mixing a substance comprised of two constituents contained in a cartridge (12) and having a cartridge holder (32) thereabout, the device comprising a plunger rod (46) for pushing a closure member (20) to permit the transfer of a diluent in a second chamber (28) through a by-pass channel (24) to mix with a constituent in a first chamber (26), the plunger rod (48) being driven by means of a rack (48) and a pinion gear (50) arrangement to prevent overly rapid movement of the plunger rod (46).

10. 发明公开

EP2109435A1 AIRLESS MIXING WITH A BY-PASS SYRINGE 有权
标题翻译：带有旁通将注射器空气LOOSE合剂
公开(公告)号：EP2109435A1
公开(公告)日：2009-10-21
申请号：EP08706270.9
申请日：2008-01-21
申请人： DUOJECT MEDICAL SYSTEMS INC
发明人： REYNOLDS, David, L. , MACDONALD, Daniel , McCARTHY, Roger
IPC分类号： A61J1/14 , A61M5/31
CPC分类号： A61M5/385 , A61J1/201 , A61J1/2055 , A61J1/2096
摘要： A transfer and mixing device which utilizes a by-pass cartridge (12) and a syringe (20). After mixing the dry component and the diluent in the by-pass cartridge (12), the mixture can be passed to a syringe (20) which includes a syringe plunger (72) having a fluid passageway (74) therein with a hydrophobic membrane (76) covering the passageway (74). The mixture can be transferred back and forth between the by-pass cartridge (12) and the syringe (20) through a small bore (60) to achieve mixing, particularly in the case of microspheres held in suspension.

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