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1. 发明公开

EP3370804A1 CARTRIDGE CARRIER ASSEMBLY 有权
公开(公告)号：EP3370804A1
公开(公告)日：2018-09-12
申请号：EP16791374.8
申请日：2016-11-02
申请人： Sanofi-Aventis Deutschland GmbH
发明人： HELMER, Michael
IPC分类号： A61M5/20 , A61M5/24 , A61M5/32
CPC分类号： A61M5/2466 , A61M5/2033 , A61M5/24 , A61M5/32 , A61M5/3202 , A61M5/343 , A61M2005/2073 , A61M2005/247
摘要： A cartridge carrier assembly for a medicament delivery device comprises a cartridge carrier adapted to receive a cartridge defining a cavity containing a dose of a medicament, a needle hub being part of the cartridge carrier or coupled to the cartridge carrier such that the needle hub is fixed relative to the cartridge carrier, the needle hub adapted to receive a distal end or part of the cartridge, an injection needle having a tipped proximal needle section adapted to pierce a sealing element distally arranged on the cartridge, and a removable needle cap attachable to a distal end of the cartridge carrier. The needle hub comprises a cartridge retention feature adapted to abut the cartridge or a part thereof to limit axial movement of the cartridge in the distal direction such that the proximal needle section is spaced from the sealing element.

2. 发明公开

EP3335747A1 INJECTOR AND METHOD OF ASSEMBLY 有权
公开(公告)号：EP3335747A1
公开(公告)日：2018-06-20
申请号：EP18155148.2
申请日：2012-10-11
申请人： Amgen Inc.
发明人： TAN-MALECKI, Francisca , FORSTER, Ron , NUNN, Scott , HOLT, Mark D. , TRAN, Son , MOBERG, Sheldon
IPC分类号： A61M5/24
CPC分类号： A61M5/31 , A61M5/14244 , A61M5/1452 , A61M5/148 , A61M5/158 , A61M5/162 , A61M5/1626 , A61M5/172 , A61M5/2455 , A61M5/2466 , A61M2005/247 , A61M2005/2474 , A61M2005/3114 , A61M2207/00 , B65B3/003 , B65B7/2821 , B65B55/08 , B65B55/10
摘要： An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

3. 发明公开

EP3322462A1 MEDICAMENT PACKAGING 审中-实审
公开(公告)号：EP3322462A1
公开(公告)日：2018-05-23
申请号：EP16753683.8
申请日：2016-07-13
申请人： Owen Mumford Limited
发明人： COWE, Toby , EVANS, Timothy , WEBB, Colin , MALLON, Jake
IPC分类号： A61M5/24
CPC分类号： A61M5/2455 , A61M5/24 , A61M2005/2403 , A61M2005/2407 , A61M2005/247
摘要： A cartridge (100) for packaging a medicament and being suitable for use with multiple different types of dosing device is described, together with dosing devices and adaptors for dosing devices. The cartridge includes a generally tubular body (102) having an interior cavity (104), a closure member (106) disposed at a distal end of the body and comprising a sealing element (128), a piston member (108) disposed in the cavity to contain the medicament between the piston member and the sealing element (128), a coupling element (114) disposed at the distal end of the body for coupling the cartridge to a dosing device (200) or to an adaptor for a dosing device, and a seal arrangement (126, 129) for receiving a sealing element release member (214) of the dosing device or adaptor. The coupling element (114) is arranged for engagement with an engagement part (220) of the dosing device or adaptor to clip the cartridge (100) to the dosing device or adaptor (200) upon insertion of the cartridge to the dosing device or adaptor, and the seal arrangement (126, 129) is disposed distally with respect to the sealing element (128) and is arranged to form a seal around the release member (214; 254) when the cartridge is coupled to the dosing device or adaptor.

4. 发明授权

EP3045189B1 INJECTOR AND METHOD OF ASSEMBLY 有权转让
公开(公告)号：EP3045189B1
公开(公告)日：2018-04-25
申请号：EP16156580.9
申请日：2012-10-11
申请人： Amgen Inc.
发明人： TAN-MALECKI, Francisca , FORSTER, Ron , NUNN, Scott , HOLT, Mark D. , TRAN, Son , MOBERG, Sheldon
IPC分类号： A61M5/24
CPC分类号： A61M5/31 , A61M5/14244 , A61M5/1452 , A61M5/148 , A61M5/158 , A61M5/162 , A61M5/1626 , A61M5/172 , A61M5/2455 , A61M5/2466 , A61M2005/247 , A61M2005/2474 , A61M2005/3114 , A61M2207/00 , B65B3/003 , B65B7/2821 , B65B55/08 , B65B55/10
摘要： An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

5. 发明公开

EP3307355A1 CHILD-RESISTANT DISCHARGER 审中-公开
标题翻译：抗儿童放电器
公开(公告)号：EP3307355A1
公开(公告)日：2018-04-18
申请号：EP16753284.5
申请日：2016-07-29
申请人： Sulzer Mixpac AG
发明人： ZÜND, Marco
IPC分类号： A61M5/24 , A61M5/28 , B65D81/00 , A61M5/315 , A61M5/31
CPC分类号： A61M5/348 , A61C5/62 , A61C5/66 , A61J7/0053 , A61M5/24 , A61M5/2429 , A61M5/2466 , A61M5/28 , A61M5/288 , A61M5/3137 , A61M5/31571 , A61M15/0068 , A61M35/003 , A61M2005/2073 , A61M2005/247
摘要： The present disclosure relates to a discharger for discharging a predetermined amount of fluid and to a discharge system comprising the discharger. The discharger comprises a housing defining a longitudinal axis and having a proximal end and a distal end, a discharge section having a discharge passage for the fluid extending between an inlet opening and an outlet opening of the discharge section, a carriage cooperating with the proximal end region of the housing such that the carriage is moveable relative to the housing along the longitudinal axis, and securing means being engageable with each other such that they define a locking position in which the carriage is prevented from being moved along the longitudinal axis, the securing means being disengageable to define a starting position for the carriage by simultaneously applying a first actuating force to the housing and a second actuating force to the carriage.

6. 发明授权

EP3151886B1 ACTIVATING MECHANISM FOR A MEDICAMENT DELIVERY DEVICE AND MEDICAMENT DELIVERY DEVICE 有权
标题翻译：一种药物输送装置和药物输送装置的激活机构
公开(公告)号：EP3151886B1
公开(公告)日：2018-04-18
申请号：EP15726611.5
申请日：2015-06-03
申请人： SANOFI
发明人： HELMER, Michael
IPC分类号： A61M5/24
CPC分类号： A61M5/2466 , A61M5/3204 , A61M5/326 , A61M2005/247 , A61M2005/2474 , A61M2005/3267
摘要： The invention relates to an activating mechanism for a medicament delivery device (1), comprising: —an outer body (8), —a cartridge (2) containing a dosage of a medicament and sealed with a sealing element (2.1) that is arranged across an open distal end of the cartridge (2), —a cartridge carrier (4) adapted to hold the cartridge (2), —a needle safety mechanism adapted to hold a double-ended hollow needle (6) and to relatively move along a longitudinal axis (L) with respect to the cartridge (2) and to the outer body (8) to cover or to expose the needle (6), —wherein in an initial position (P1) of the medicament delivery device (1), the double-ended hollow needle (6) is spaced from the cartridge (2) in a distal direction (D), and —wherein when the needle safety mechanism is pressed into the outer body (8), a proximal end of the needle (6) pierces the sealing element (2.1). The invention further relates to a medicament delivery device (1) comprising such an activating mechanism.

7. 发明公开

EP3174580A4 INJECTION SYSTEM 有权
公开(公告)号：EP3174580A4
公开(公告)日：2018-04-04
申请号：EP15827601
申请日：2015-07-31
申请人： HOSPIRA INC
发明人： SUNDQUIST JOHN , RUSH BEN , BROWKA EDWARD PAUL , FOSHEE DAVID L , WILLARD GRETCHEN E , MYERS STEPHEN , RODRIGUEZ HECTOR , HORTON JOHN COLEMAN
IPC分类号： A61M5/315 , A61M5/24 , A61M5/50
CPC分类号： A61M5/31515 , A61M5/31501 , A61M5/31505 , A61M5/31513 , A61M5/347 , A61M5/50 , A61M5/502 , A61M5/508 , A61M5/5086 , A61M2005/206 , A61M2005/2073 , A61M2005/2407 , A61M2005/247 , A61M2005/312 , A61M2005/3238 , A61M2005/5073
摘要： Methods and systems for an injection system are provided. An example injection system includes a container for a pharmaceutical that is sealed at a proximal end with a plunger having a pushing surface for engaging an inner surface of the hollow body. A plunger rod extends axially from the proximal end of the container and is covered with a plunger rod cover. Removal of the cover activates the system and allows for delivery of the pharmaceutical product from the container by advancing the plunger within the container towards the seal.

8. 发明公开

EP3173113A1 AN INJECTION NEEDLE ASSEMBLY 审中-公开
标题翻译：注射针头组件
公开(公告)号：EP3173113A1
公开(公告)日：2017-05-31
申请号：EP16179487.0
申请日：2016-07-14
申请人： Sanofi-Aventis Deutschland GmbH
发明人： The designation of the inventor has not yet been filed
IPC分类号： A61M5/24 , A61M5/50 , A61M5/32 , A61B5/15 , A61M5/158 , A61M5/162 , A61M39/10
CPC分类号： A61M5/3243 , A61M5/14 , A61M5/158 , A61M5/162 , A61M5/1626 , A61M5/2466 , A61M5/3202 , A61M5/3213 , A61M5/50 , A61M5/5086 , A61M2005/247 , A61M2039/1066
摘要： The present invention relates to an injection needle assembly (16, 116, 216, 316, 416) for use in a medicament delivery device (10). The injection needle assembly comprises an injection needle holder (27), an injection needle (17) fixed to said injection needle holder (27), the injection needle (17) having a proximal end (18) and a distal end (19), and a sealing assembly (25) for sealing the distal end (19) of the injection needle (17). The sealing assembly (25) comprises a spacer element (31) surrounding the distal end (19) of the injection needle (17) and a sealing membrane (32) for sealing the distal end (19) of the injection needle (17).
摘要翻译：本发明涉及用于药物输送装置（10）的注射针组件（16,116,216,316,416）。注射针组件包括注射针保持器27，固定到所述注射针保持器27的注射针17，注射针17具有近端18和远端19，和用于密封注射针（17）的远端（19）的密封组件（25）。密封组件（25）包括围绕注射针（17）的远端（19）的隔离元件（31）和用于密封注射针（17）的远端（19）的密封膜（32）。

9. 发明公开

EP3130368A1 CHILD-RESISTANT DISCHARGER 审中-公开
标题翻译： KINDERSICHERE ENTLADER
公开(公告)号：EP3130368A1
公开(公告)日：2017-02-15
申请号：EP15179326.2
申请日：2015-07-31
申请人： Sulzer Mixpac AG
发明人： ZÜND, Marco
IPC分类号： A61M5/24 , A61C5/00 , A61M5/28 , B65D81/00 , A61M5/315 , A61M5/31
CPC分类号： A61M5/2429 , A61C5/62 , A61C5/66 , A61M5/24 , A61M5/2466 , A61M5/288 , A61M5/3137 , A61M5/31571 , A61M2005/247
摘要： The present disclosure relates to a discharger for discharging a predetermined amount of fluid and to a discharge system comprising the discharger. The discharger comprises a housing defining a longitudinal axis and having a proximal end and a distal end, a discharge section having a discharge passage for the fluid extending between an inlet opening and an outlet opening of the discharge section, a carriage cooperating with the proximal end region of the housing such that the carriage is moveable relative to the housing along the longitudinal axis, and securing means being engageable with each other such that they define a locking position in which the carriage is prevented from being moved along the longitudinal axis, the securing means being disengageable to define a starting position for the carriage by simultaneously applying a first actuating force to the housing and a second actuating force to the carriage.
摘要翻译：本公开涉及一种用于排出预定量的流体的放电器和包括放电器的放电系统。排放器包括限定纵向轴线并具有近端和远端的壳体，排出部分，其具有用于在排出部分的入口和出口之间延伸的流体的排出通道，与近端协作的托架区域，使得滑架能够相对于壳体沿着纵向轴线移动，并且固定装置可彼此接合，使得它们限定了锁定位置，在该位置中，防止滑架沿着纵向轴线移动，固定意味着通过同时向壳体施加第一致动力和向托架施加第二致动力来解除啮合以限定滑架的起始位置。

10. 发明授权

EP2699286B1 WEARABLE AUTOMATIC INJECTION DEVICE 有权
标题翻译：便携式自动注射设备
公开(公告)号：EP2699286B1
公开(公告)日：2016-08-31
申请号：EP12719852.1
申请日：2012-04-23
申请人： AbbVie Inc.
发明人： ANDERSON, Philip, D. , JULIAN, Joseph, F. , LAURUSONIS, Linas, P. , CORRIGAN, Sean , STRAHM, Chris , FIENUP, William , MATUSAITIS, Tomas
IPC分类号： A61M5/142
CPC分类号： A61M5/2053 , A61M5/002 , A61M5/14248 , A61M5/1452 , A61M5/20 , A61M5/2466 , A61M5/3202 , A61M5/3232 , A61M5/3234 , A61M35/00 , A61M2005/14252 , A61M2005/247 , Y10T29/49826
摘要： Exemplary embodiments provide wearable automatic injection devices for administering a therapeutic agent to a patient's body at fast, controlled rates, for example, in a single fast bolus. Exemplary embodiments also provide methods for assembling wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates. Exemplary embodiments also provide methods for using wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates.

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