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1. 发明公开

EP0892919A1 METHOD AND APPARATUS FOR TREATMENT OF HUMAN OR ANIMAL CELL SAMPLES 失效
标题翻译：方法和一种用于治疗人体或动物细胞样本
公开(公告)号：EP0892919A1
公开(公告)日：1999-01-27
申请号：EP97915202.0
申请日：1997-04-11
申请人： AUSTRALIAN BIOMEDICAL CORPORATION LIMITED
发明人： PALANDER, Jari
IPC分类号： G01N33 , G01N1 , G02B21
CPC分类号： G02B21/34 , G01N1/312 , Y10T436/112499
摘要： A method for treating a human or animal cell sample (4) arranged on a slide (2) comprises dispensing treatment liquid onto the slide between the sample and the leading edge (5) of a cover tile (1) having a recess or cavity (6). The leading edge is bevelled and has an opening (13) into the cavity. Once dispensing is completed the method involves moving the tile over the slide to trap the liquid in the cavity. A small volume of sealing liquid in the form of evaporation inhibitor liquid, preferably mineral oil, is then applied to the slide preferably at the leading and trailing edges of the tile in a manner causing the evaporation inhibitor liquid to wick around the entire perimeter of the tile to form an airtight seal between the tile and slide around the cavity.

2. 发明公开

EP0801732A1 METHOD AND APPARATUS FOR TREATMENT OF HUMAN OR ANIMAL CELL SAMPLES 失效
标题翻译：方法和一种用于治疗人体或动物细胞样本
公开(公告)号：EP0801732A1
公开(公告)日：1997-10-22
申请号：EP96900204.0
申请日：1996-01-04
申请人： AUSTRALIAN BIOMEDICAL CORPORATION LIMITED
发明人： PALANDER, Jari
IPC分类号： G01N33 , B01F11 , C12M3 , G01N1 , G02B21
CPC分类号： G01N1/312 , B01F11/0042 , G01N1/2813 , G02B21/34 , Y10T436/112499 , Y10T436/119163 , Y10T436/25 , Y10T436/2575
摘要： Apparatus for treatment of human or animal cell samples (4) on a microscopic slide (2) includes an element (1) having a recessed face (6) defined by rails (7) which are adapted to slide on surface (3) of the slide (2). An opening (13) at the leading edge of the element (1) has a bevelled edge (5) and provides access to a cavity (6) formed between the face and the surface (3) of the slide (2) when the rails (7) bear on the slide (2). The slide (2) is tilted slightly and a vacuum nozzle (8) is arranged at the lower edge of the slide (2). An end stop (9) may be clamped to the end of the slide (2) opposite to the end where the nozzle (8) is located and has a bevelled edge complimentary to the bevelled edge (5) of the element (1) for closing the opening (13). A method of spreading liquid over the surface (3) and the sample (4) involves placing the rails (7) on the surface (3) with the cavity (6) displaced laterally from the sample (4) and the face (6) and surface (3) parallel, dispensing the liquid onto the surface (3) and moving the element (1) relative to the surface (3) whereby the liquid becomes trapped in the cavity (6), and is spread evenly over the sample (4). The method also involves removing excess liquid after incubation by exposing the cavity (6) to the vacuum nozzle by sliding the element (1) over the lower edge of the slide (2) and allowing the nozzle to suck the excess liquid away. Further treatment liquid may be added adjacent to the opening during the suction process to provide a second treatment without exposing the sample (4) to air between treatments.

3. 发明公开

EP0539379A4 AUTOMATIC TISSUE STAINING FOR IMMUNOHISTOCHEMISTRY 失效
标题翻译：自动组织化学免疫组织化学
公开(公告)号：EP0539379A4
公开(公告)日：1993-06-02
申请号：EP91908695
申请日：1991-04-29
申请人： AUSTRALIAN BIOMEDICAL CORPORATION LIMITED
发明人： HEALEY, KEVIN , BAXTER, GRAHAM, LESLIE
IPC分类号： B05B1/34 , G01N1/30 , G01N1/31 , G01N33/53 , G01N33/533 , G01N35/04 , G01N1/28 , G01N35/00
CPC分类号： B05B1/3436 , G01N1/312 , G01N2001/317
摘要： Apparatus (10) for the automatic staining of tissue includes a body (12) on which a carousel (16) rotates. The carousel (16) is able to carry a number of slides (24) bearing tissue samples. A delivery head assembly (18) is mounted on the body (12) for movement across the diameter of the carousel (16). The head assembly contains a clear nozzle (20) and a spray nozzle (22). A version (50) of the spray nozzle (22) for spraying a fluid biochemical agent onto a slide (24) has a main body (52) a plug (56) in the main body (52) and a cap (54) on the main body (52) between which there is a swirl chamber (68) into which fluid passes from the body (52). The fluid enters the swirl chamber (68) such that flow in the chamber (68) is concentric to the chamber axis and thereafter flows from the body (52) through an exit (66), thus minimising damage to the biochemical agent.

4. 发明公开

EP0539379A1 AUTOMATIC TISSUE STAINING FOR IMMUNOHISTOCHEMISTRY 失效
标题翻译：织物自动染料免疫组化。
公开(公告)号：EP0539379A1
公开(公告)日：1993-05-05
申请号：EP91908695.0
申请日：1991-04-29
申请人： AUSTRALIAN BIOMEDICAL CORPORATION LIMITED
发明人： HEALEY, Kevin , BAXTER, Graham, Leslie
IPC分类号： B05B1 , G01N1 , G01N33 , G01N35
CPC分类号： B05B1/3436 , G01N1/312 , G01N2001/317
摘要： Appareil (10) effectuant la coloration automatique des tissus, comprenant un corps (12) sur lequel tourne un plateau circulaire (16). Le plateau circulaire (16) peut porter une pluralité de lamelles (24) portant des échantillons de tissus. Un ensemble de tête d'alimentation (18) est monté sur le corps (12) de manière à se déplacer sur tout le diamètre du plateau circulaire (16). L'ensemble de tête comprend un ajutage nettoyeur (20) et un ajutage pulvérisateur (22). Une version (50) de l'ajutage pulvérisateur (22) permettant de pulvériser un agent biochimique liquide sur une lamelle (24) comprend un corps principal (52), un élément d'obturation (56) dans le corps principal (52) et un chapeau (54) situé sur ledit corps principal (52), entre lesquels se trouve une chambre de tourbillonnement (68) dans laquelle passe le liquide provenant du corps (52). Le liquide pénètre dans la chambre de tourbillonnement (68) de telle sorte que l'écoulement dans la chambre (68) est concentrique à l'axe de la chambre et qu'il s'écoule ensuite du corps (52) par un orifice de sortie (66), ceci minimisant par conséquent la détérioration de l'agent biochimique.

5. 发明公开

EP0195035A1 HAND SURGERY TABLE 失效
标题翻译：表手外科。
公开(公告)号：EP0195035A1
公开(公告)日：1986-09-24
申请号：EP85904587.0
申请日：1985-09-17
申请人： AUSTRALIAN BIOMEDICAL CORPORATION LIMITED
发明人： YOUNG, David, Alexander
IPC分类号： A61B19 , A61G13
CPC分类号： A61G13/12 , A61G13/0045 , Y10T403/11 , Y10T403/32803 , Y10T403/7015
摘要： Une table pour chirurgie de la main comprend une plateforme (3) et un joint universel (6) qui connecte cette plateforme (3) à une base (5), la position de la plateforme (3) par rapport à la base (5) pouvant ainsi être modifiée selon les besoins. Un dispositif de blocage (13) bloque la plateforme (3) dans une position sélectionnée. La plateforme (3) peut être connectée de façon libérable à la structure de soutien (2) de la table de sorte qu'elle puisse être détachée pour nettoyage ou décharge, et un ergot frangible (26) peut être prévu pour indiquer que la plateforme (3) a déjà été utilisée. Plusieurs colonnes de soutien (41) peuvent être attachées à la plateforme (3) dans une pluralité de positions diverses sur toute la surface supérieure de la plateforme (3). Au moins certains de ces supports (41) ont une extrémité supérieure profilée. Les colonnes de soutien (41) coopèrent avec des orifices (31) dans la plateforme (3) qui servent également d'orifices de drainage.

6. 发明公开

EP0888554A1 SPECIMEN PREPARATION 失效
标题翻译：样品制备
公开(公告)号：EP0888554A1
公开(公告)日：1999-01-07
申请号：EP97900160.0
申请日：1997-01-17
申请人： AUSTRALIAN BIOMEDICAL CORPORATION LIMITED
发明人： MEIKLE, Peter, John
IPC分类号： B65H3 , G01N1 , G01N35
CPC分类号： G01N35/1079 , G01N1/2813 , G01N1/312 , G01N35/1004
摘要： A closed tube sampling apparatus (14) for drawing a specimen sample tube (16) having a pierceable cap comprises a tube loading carousel (15) in which sample tubes are radially disposed and indexed in turn to an aspirate position. A needle carrier (42) is moveable linearly to move an aspirate needle (17) from a park position where the needle is in a wash station (47) to an aspirate position where the needle extends through said wash station and pierces said cap for the purpose of aspirating a sample from the tube. The needle wash station is also moveable relative to the needle carrier and is spring (49) biased to bear on said cap and prevent withdrawal of the cap as said needle is withdrawn. A dispensing pipette (20) is in fluid communication with said needle and subsequently dispenses said sample onto a slide. A slide transfer apparatus for sequentially transferring single slides (40) from a stack of slides onto a slide conveyor (12) includes a pickup head (11) having a bellows type suction cup (39) for lifting and holding slides. A fixed optical sensor (34) detects a home position of the pickup head and the travelling optical sensor (36) on the head detects when a slide is held and released from the head. The degree of movement of the head in releasing a slide is detectable by the travelling sensor (36) and thereby a microprocessor is able to determine whether one or two slides have been transferred by the head from the stack to the conveyor. The amount of movement of the head from the home position to the top of the stack and from the home position to the top of the conveyor is also determined by the microprocessor which in determining all movements counts the revolutions of a stepper motor which is responsible for such movement.

7. 发明公开

EP0834096A1 COVERSLIP PICK-UP AND LAYDOWN APPARATUS 失效
标题翻译： COVERERSLIP捡拾和铺设设备
公开(公告)号：EP0834096A1
公开(公告)日：1998-04-08
申请号：EP96917280.0
申请日：1996-06-14
申请人： AUSTRALIAN BIOMEDICAL CORPORATION LIMITED
发明人： ELLIOTT, Stuart, Stanley
IPC分类号： G01N1 , B65H3 , B65H37 , G02B21
CPC分类号： G01N1/312 , B65H3/0816 , B65H37/00 , B65H2301/5121 , G02B21/32 , G02B21/34 , Y10T156/1132 , Y10T156/1744 , Y10T156/1944
摘要： A coverslip pick-up and transfer head (10) comprises a pair of spaced suction cups (26) which are angled downwardly and outwardly. A spring loaded plunger (13) in an extended condition extends below the suction cups such that when a cover slip (16) is held by the suction cups it is flexed in a concave shape. A solenoid (15), when energised, retracts the plunger against the spring force. In use a coverslip magazine (17) containing a stack of coverslips is raised under the head causing the plunger to retract until the suction cups contact the coverslips. Vacuum is applied to the suction cups and the magazine lowered whereby the coverslip is held by the suction cups and flexed into a concave shape. The solenoid is energised momentarily causing the plunger to retract and extend thereby delivering a gentle flexural pulse to the coverslip causing any further coverslip adhered to the underside of the top coverslip to be released and returned to the magazine. A coverslip laydown head (19) includes a pivotal lever (23) which is spring biased to provide a progressive force along the coverslip as it is layed on a slide at an ever decreasing angle to thereby cause mountant on the slide to spread evenly over the slide with a uniform wavefront.
摘要翻译：盖玻片拾取和转移头（10）包括一对向下和向外倾斜的隔开的吸盘（26）。处于伸展状态的弹簧加载柱塞（13）在吸盘下方延伸，使得当吸盘保持盖片（16）时，其被弯曲成凹形。螺线管（15）通电后，克服弹簧力将柱塞收回。在使用中，包含一叠盖玻片的盖玻片盒（17）在头部下方升起，导致柱塞缩回，直到吸杯接触盖玻片。真空被施加到吸盘上并且盒子降低，由此盖玻片被吸盘保持并弯曲成凹形。螺线管瞬时被激励，导致柱塞缩回并延伸，从而向盖玻片提供温和的弯曲脉冲，从而使附着于顶盖玻片下侧的任何其他盖玻片释放并返回到弹匣。盖玻片放置头（19）包括枢转杠杆（23），该枢转杠杆（23）被弹簧偏置以沿着盖玻片提供渐进的力，因为它以不断减小的角度铺设在载玻片上，从而导致在载玻片上的安装剂均匀地分布在盖玻片以均匀的波前滑动。

8. 发明授权

EP0195035B1 HAND SURGERY TABLE 失效
标题翻译：手术台
公开(公告)号：EP0195035B1
公开(公告)日：1990-04-25
申请号：EP85904587.4
申请日：1985-09-17
申请人： AUSTRALIAN BIOMEDICAL CORPORATION LIMITED
发明人： YOUNG, David, Alexander
IPC分类号： A61G13/00
CPC分类号： A61G13/12 , A61G13/0045 , Y10T403/11 , Y10T403/32803 , Y10T403/7015
摘要： A hand surgery table having a platform (3) and a universal-type joint (6) connecting that platform (3) to a base (5) whereby the disposition of the platform (3) relative to the base (5) can be varied to suit requirements. Locking means (13) is provided to releasably secure the platform (3) in a selected disposition. The platform (3) is releasably connectable to the support structure (2) of the table so that it can be separated for cleaning or disposal, and a frangible detent (26) may be provided to show that the platform (3) has been previously used. A plurality of column supports (41) are attachable to the platform (3) at any of a plurality of positions across the upper surface of the platform (3) and at least some of those supports (41) have a contoured upper end. The column supports (41) cooperate with holes (31) in the platform (3) which also serve as drainage holes.

9. 发明公开

EP0640209A1 AUTOMATIC STAINING APPARATUS FOR SLIDE SPECIMENS 失效
标题翻译：设备对于一般样品的自动颜色。
公开(公告)号：EP0640209A1
公开(公告)日：1995-03-01
申请号：EP93909668.0
申请日：1993-05-13
申请人： AUSTRALIAN BIOMEDICAL CORPORATION LIMITED
发明人： KEEFE, Raymond
IPC分类号： G01N33 , G01N1 , G01N35
CPC分类号： G01N1/312 , G01N35/0092 , G01N2035/0093 , G01N2035/041 , G01N2035/0498 , Y10T436/114165
摘要： Apparatus for the automatic staining of tissue slide specimens has a casing (12) enclosing a plurality of baths (20) arranged in an array and a carriage (24), which includes a hoist (25), guide rail (26), cross member (23) and hooks (22). Carriage (24) moves cross member (23) in any XYZ direction and with hook (22) is selectively able to engage and move a rack (21) containing tissue slide specimens between baths (20). The apparatus further includes a microprocessor for controlling the movement of the carriage such that one or more racks (21) may be processed through the apparatus. The microprocessor contains logic whereby multiple schedules can operate simultaneously and additional schedules can be commenced without disruption to schedules currently operating.

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