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1. 发明公开

EP4404999A1 NEEDLE WITH VENTING GROOVES 审中-实审
公开(公告)号：EP4404999A1
公开(公告)日：2024-07-31
申请号：EP22797302.1
申请日：2022-09-25
申请人： Accroma Labtec AG
发明人： SALADIN, Sven , GAFNER, Stefan
IPC分类号： A61M5/168 , G01N1/14 , G01N35/00 , G01N35/10 , B01L3/02
CPC分类号： A61M5/168 , B01L2200/14120130101 , B01L2200/02620130101 , B01L2200/068420130101 , G01N35/1079 , B01L3/0289

3. 发明授权

EP2430456B1 SYSTEM AND METHOD FOR AUTOMATICALLY VENTING AND SAMPLING A CULTURE SPECIMEN CONTAINER 有权
公开(公告)号：EP2430456B1
公开(公告)日：2018-12-12
申请号：EP10769101.6
申请日：2010-05-14
申请人： Biomerieux, Inc
发明人： RONSICK, Christopher, S. , WILSON, Mark, S. , ROBINSON, Ronnie, J. , WALSH, John, D. , HYMAN, Jones
IPC分类号： G01N35/00
CPC分类号： C12Q1/24 , G01N35/0099 , G01N35/1079 , Y10S901/30
摘要： Apparatus for automated venting and/or sampling of a specimen container having a closure sealing the interior of the specimen container from the environment is disclosed. The apparatus includes a rack holding the specimen container; a venting and/or sampling device having a needle, a chamber in fluid communication with the needle and a port in fluid communication with the chamber; a robotic transfer mechanism movable relative to the rack; a sample removal apparatus attached to the robotic transfer mechanism having gripping features for gripping the venting device. The sample removal apparatus and robotic transfer mechanism are movable relative to the specimen container so as to automatically insert the needle of the venting device through the closure of the specimen container to thereby vent the interior of the specimen container and obtain equilibrium between the interior of the specimen container and the atmosphere and withdraw a portion of the sample from the specimen container into the venting and/or sampling device.

4. 发明授权

EP3080615B1 REAGENT VESSEL HOLDER FOR AN ANALYTICAL INSTRUMENT, REAGENT SUPPLY SYSTEM FOR AN ANALYTICAL INSTRUMENT AND AN ANALYTICAL INSTRUMENT 有权转让
公开(公告)号：EP3080615B1
公开(公告)日：2018-07-25
申请号：EP14812212.0
申请日：2014-12-11
申请人： Roche Diagnostics GmbH , F. Hoffmann-La Roche AG , Hitachi High-Technologies Corporation
发明人： SATTLER, Stephan , KRAEMER, Reinhold , KOMATSU, Hidenobu , SUZUKI, Toshio
IPC分类号： G01N35/10 , B01L3/00 , B01L9/00
CPC分类号： B01L3/523 , B01L3/527 , B01L9/00 , B01L2200/023 , B01L2200/025 , B01L2200/16 , B01L2300/044 , B01L2300/045 , B01L2300/0672 , G01N35/00663 , G01N35/1002 , G01N35/1079 , G01N2035/00673
摘要： A reagent vessel holder for an analytical instrument is disclosed. The reagent vessel holder comprises at least one reagent vessel compartment for receiving a reagent vessel, wherein the reagent vessel compartment comprises a base and at least two lateral guiding elements, and at least one hollow needle for piercing the reagent vessel. The hollow needle is disposed on a front end of the reagent vessel compartment near the base and extends in a direction substantially parallel to the base. The lateral guiding elements are disposed so as to be adapted to slidably guide the reagent vessel in a direction substantially parallel to the direction, in which the hollow needle extends. The lateral guiding elements are adapted to receive the reagent vessel therebetween and are biased towards one another. Further, a reagent supply system for an analytical instrument and an analytical instrument comprising such a reagent vessel holder are disclosed.

5. 发明公开

EP3101431A4 AUTOMATIC ANALYTICAL APPARATUS 有权转让
公开(公告)号：EP3101431A4
公开(公告)日：2017-10-25
申请号：EP15740185
申请日：2015-01-09
申请人： HITACHI HIGH-TECHNOLOGIES CORP
发明人： MURAMATSU YOSHIKI , MORI TAKAMICHI , NAKAMURA KAZUHIRO
IPC分类号： G01N35/10 , G01N33/49
CPC分类号： G01N35/1016 , G01N33/49 , G01N35/1011 , G01N35/1079 , G01N2035/1018

6. 发明授权

EP2983824B1 CAP FOR RECEPTACLE FOR USE IN AUTOMATED REAGENT-BASED ASSAYS 有权
标题翻译：用于在自动化试剂测定中使用的吸附盖
公开(公告)号：EP2983824B1
公开(公告)日：2017-09-27
申请号：EP14720813.6
申请日：2014-03-13
申请人： Gen-Probe Incorporated
发明人： KNIGHT, Byron, J. , BUSE, David , GROELI, Julian
IPC分类号： B01L3/00
CPC分类号： G01N35/1002 , B01L3/502 , B01L3/5082 , B01L3/50825 , B01L3/5085 , B01L3/50853 , B01L3/50855 , B01L3/523 , B01L3/527 , B01L2200/02 , B01L2200/025 , B01L2200/026 , B01L2200/0668 , B01L2200/0689 , B01L2200/141 , B01L2200/142 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/047 , B01L2300/048 , B01L2300/0609 , B01L2300/0829 , B01L2300/0832 , B01L2300/0838 , B01L2300/0851 , B01L2300/0858 , B01L2300/12 , B01L2400/0406 , B65B69/00 , B65D1/0207 , B65D1/34 , B65D1/36 , B65D17/50 , B65D39/0017 , B65D39/0029 , B65D2539/003 , C12Q1/686 , G01N30/6091 , G01N35/0099 , G01N35/026 , G01N35/10 , G01N35/1079 , G01N2035/00287 , Y10T436/11
摘要： There is disclosed a multi-well tray for use in an automated instrument and comprising: a base having a first end and a second end, said base comprising a top surface and opposed side walls extending from the top surface to a bottom surface and an arm extending from the first end of the base and configured to be engaged by a transport mechanism for transporting the tray within the instrument; a plurality of wells depending from the top surface and disposed between the opposed side walls, each having an opening at the top surface; and snap fingers disposed at the second end of the base and configured to grasp an element of the instrument for securing the tray to the element.
摘要翻译：用于进行反应的物品包括具有侧壁，底壁和开放的上端的试剂井。冻干的试剂通过非整体式保留特征被保留在孔内，所述保留特征插入孔的开放上端并固定到试剂上方的侧壁。保留特征中的开口小于试剂的直径，但其大小允许移液管尖端插入井中。保持部件可以是固定到侧壁的轴环并且可以包括轴向延伸到井中的指状物。凹槽和保持特征可以相应地变细。用于重构冻干试剂的方法包括以下步骤：将附着于自动移液器的移液管吸头吸入一定量的稀释剂，并将稀释剂分配到试剂孔中，从而重新构成冻干试剂。

7. 发明公开

EP3155421A1 CONTAINER FOR DETERMINING OF ANALYTES AND/OR CHEMICO-PHYSICAL PARAMETERS, AS WELL AS DETERMINING OF URINARY SEDIMENT, IN URINE; AND METHOD OF FULL URINE ANALYSIS USING THIS CONTAINER 有权
标题翻译：容器分析物和/或CHEMIKOPHYSIKALISCHEN参数的测定及Harnsediment作者完整尿液分析尿液和法测定使用此容器
公开(公告)号：EP3155421A1
公开(公告)日：2017-04-19
申请号：EP15736631.1
申请日：2015-06-11
申请人： Sikeliup S.r.l.
发明人： SPEZIALE, Danila Giuseppa Maria
IPC分类号： G01N33/493 , G01N31/22 , B01L3/00
CPC分类号： G01N33/493 , B01L3/502 , B01L2200/0689 , B01L2300/021 , B01L2300/044 , B01L2300/0825 , B01L2300/0832 , G01N21/80 , G01N31/221 , G01N31/227 , G01N35/1016 , G01N35/1079
摘要： The present invention relates to a container (1) apt to contain urine, for the determination of analytes and/or chemico-physical parameters, and of urinary sediment, via an automated analyzer, the container comprising a) a containment region (9) having an opening (3) with a tightenable and pierceable closure element (4); b) a reading region (5) with one or more colorimetric reaction pads (6) made integral with an inner wall of the container; c) an impermeable and pierceable separation septum (10) positioned between the containment region (9) and the reading region (5). The present invention also relates to a method of running a full test of urine on an automated analyzer, including physical-chemical examination and urine sediment, which comprises the steps of a) filling the above-mentioned container (1) from a primary collection container by suction regulated from pre-calibrated vacuum; b) loading the container (1) on the automatic analyzer; c) piercing the closure element (4) with a sampler and mixer needle (20); d) mixing the sample in the containment region (9) and withdrawing some urine to be transferred to the analyzer for the automatic reading of the urinary sediment e) piercing the septum (10) and retracting the sampler needle (20) such that urine flows into the reading region (5) f) waiting for a specified time for the generation of color reactions; g) performing an automatic reading of the colorimetric reactions using a sensor integrated in the analyzer.
摘要翻译：本发明涉及一种容器（1）易于在自动分析装置包含尿，用于分析物和/或物理化学参数的测定，和尿沉渣的，通过，该容器包括：a）容纳区域（9），其具有具有紧缩和能够刺穿闭合元件开口（3）（4）; b）中的读取区域（5）与一个或多个比色反应垫（6）制成一体在容器的内壁上; C）（以和不可渗透的可刺穿隔膜分离（10）的容纳区域（9）和所述读取区域5）之间的位置。因此，本发明涉及上运行的尿全测试的方法（在自动化分析仪，包括物理 - 化学检查和尿沉淀物，其包括以下步骤：a）从一个第一采集容器填充上述容器1）通过抽吸从预校准的真空调节; B）加载在自动分析仪的容器（1）; c）中刺穿与采样混频器和针（20）的封闭元件（4）; d）将在所述容纳区域（9样品）和回抽一些尿液转移到分析仪上用于尿沉渣e的自动读数）刺穿所述隔膜（10）和缩回取样针（20）检测并尿流动到读取区域（5）F）等待对显色反应的产生在规定的时间; 使用集成到分析仪中的传感器测色反应的自动读取克）表演。

8. 发明公开

EP3093668A1 AUTOMATED ANALYZER 有权转让
标题翻译：自动分析仪
公开(公告)号：EP3093668A1
公开(公告)日：2016-11-16
申请号：EP15734929.1
申请日：2015-01-05
申请人： Hitachi High-Technologies Corporation
发明人： YASUI Akihiro , SUZUKI Yoshihiro , NAKAMURA Kazuhiro , TOKIEDA Hitoshi
IPC分类号： G01N35/10 , G01N35/04
CPC分类号： G01N35/1011 , G01N35/1079 , G01N2035/0412 , G01N2035/0453 , G01N2035/1025
摘要： There is provided an automatic analysis device which can properly control an operation of a dispensing nozzle by identifying a target with which the dispensing nozzle comes into contact, and which can avoid damage to the dispensing nozzle. In a case where a sample container 15 has a rubber-made lid 35, if a sample nozzle 12a descends and comes into contact with the lid 35, the sample nozzle 12a is relatively moved inside an arm 42 as far as a lid detection distance 48, and a detector 44 detects a detection plate 43. A fact that the sample nozzle 12a comes into contact with the lid 35 is stored together with position information of the sample nozzle 12a, into an operation commanding unit. The sample nozzle 12a further continues to descend, and a suction operation of a sample 34 is performed at a predetermined position. In a case where the sample nozzle 12a collides with a frame portion 36 of the lid 35 and external force is applied thereto, the detector 44 detects that the detection plate 43 is relatively moved as far as the detection distance 48. Thereafter, the sample nozzle 12a stops descending, when excessive external force is applied due to the sample nozzle 12a trying to descend and the detection plate 43 is relatively moved as far as an obstacle detection distance 49.
摘要翻译：提供了一种自动分析装置，其可以通过识别分配喷嘴接触的目标来适当地控制分配喷嘴的操作，并且可以避免对分配喷嘴的损坏。在样本容器15具有橡胶制成的盖子35的情况下，如果样品喷嘴12a下降并与盖子35接触，则样本喷嘴12a在臂42内相对移动到盖检测距离48 检测器44检测出检测板43.试样喷嘴12a与盖35接触的事实与采样喷嘴12a的位置信息一起存储到操作指令单元中。样本喷嘴12a进一步下降，并且在预定位置执行样品34的抽吸操作。在样本喷嘴12a与盖35的框架部36碰撞并施加外力的情况下，检测器44检测到检测板43相对移动到检测距离48之前。此后，样本喷嘴当试样喷嘴12a试图下降并且检测板43被相对移动到障碍物检测距离49时，施加过大的外力时，12a停止下降。

9. 发明公开

EP2672273A4 INSPECTION CHIP, AND INSPECTION CHIP SET PROVIDED WITH THE INSPECTION CHIP 失效转让
标题翻译：检查CHIP性质和检查芯片EQUIPPED检查芯片组
公开(公告)号：EP2672273A4
公开(公告)日：2016-07-06
申请号：EP12742431
申请日：2012-01-18
申请人： KONICA MINOLTA INC
发明人： WADA SHIGERU
IPC分类号： G01N35/02 , G01N37/00
CPC分类号： B01L3/021 , B01L3/0275 , B01L3/502715 , B01L2200/027 , B01L2200/0689 , B01L2300/044 , B01L2300/0636 , B01L2300/0877 , B01L2400/0487 , G01N21/05 , G01N21/648 , G01N33/48707 , G01N35/1079 , G01N2021/058 , G01N2035/00158
摘要： The present invention discloses an arrangement provided with a chip body having a fluid channel and configured such that an end portion of the fluid channel is opened in a surface of the chip body, and a sheet-like seal member which covers at least the opening in the surface of the chip body for bringing the inside of the fluid channel to a sealed state. The seal member is constituted of laminated sheet members including a first sheet member having a ductility and an elasticity capable of forming a hole therein with use of a nozzle member, and a second sheet member having a lower ductility than the first sheet member. The sheet members adjoining each other are adhered to each other by an adhesive or a tackifier. The second sheet member is disposed on the chip body side than the first sheet member.

10. 发明公开

EP2983824A2 SYSTEMS, METHODS, AND APPARATUSES FOR PERFORMING AUTOMATED REAGENT-BASED ASSAYS 有权
标题翻译：用于进行自动化的基于试剂的测定的系统，方法和装置
公开(公告)号：EP2983824A2
公开(公告)日：2016-02-17
申请号：EP14720813.6
申请日：2014-03-13
申请人： Gen-Probe Incorporated
发明人： KNIGHT, Byron, J. , BUSE, David , GROELI, Julian
IPC分类号： B01L3/00
CPC分类号： G01N35/1002 , B01L3/502 , B01L3/5082 , B01L3/50825 , B01L3/5085 , B01L3/50853 , B01L3/50855 , B01L3/523 , B01L3/527 , B01L2200/02 , B01L2200/025 , B01L2200/026 , B01L2200/0668 , B01L2200/0689 , B01L2200/141 , B01L2200/142 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/047 , B01L2300/048 , B01L2300/0609 , B01L2300/0829 , B01L2300/0832 , B01L2300/0838 , B01L2300/0851 , B01L2300/0858 , B01L2300/12 , B01L2400/0406 , B65B69/00 , B65D1/0207 , B65D1/34 , B65D1/36 , B65D17/50 , B65D39/0017 , B65D39/0029 , B65D2539/003 , C12Q1/686 , G01N30/6091 , G01N35/0099 , G01N35/026 , G01N35/10 , G01N35/1079 , G01N2035/00287 , Y10T436/11
摘要： There is disclosed a multi-well tray for use in an automated instrument and comprising: a base having a first end and a second end, said base comprising a top surface and opposed side walls extending from the top surface to a bottom surface and an arm extending from the first end of the base and configured to be engaged by a transport mechanism for transporting the tray within the instrument; a plurality of wells depending from the top surface and disposed between the opposed side walls, each having an opening at the top surface; and snap fingers disposed at the second end of the base and configured to grasp an element of the instrument for securing the tray to the element.
摘要翻译：提供了用于执行自动化的基于试剂的分析的系统，装置和方法。还提供了用于将盖子自动附接到反应容器的方法，以及从盖帽的反应容器自动移除盖子的方法。

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