专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明公开

EP3355038A1 IMAGING APPARATUS AND OPERATING METHOD 有权
公开(公告)号：EP3355038A1
公开(公告)日：2018-08-01
申请号：EP17152984.5
申请日：2017-01-25
申请人： Specim, Spectral Imaging Oy Ltd
发明人： Puusaari, Jarkko
IPC分类号： G01J3/28 , G01J3/02 , G02B21/00 , G02B21/24 , G02B21/36
CPC分类号： G02B7/04 , G01J3/2803 , G01J3/2823 , G01J2003/2813 , G02B21/006 , G02B21/245 , G02B27/10 , H04N5/2253
摘要： An imaging apparatus comprises a first detector (100) configured to capture a two-dimensional image; a second detector (102) configured to perform single-line imaging and spatially displaced with respect to the first detector (100); an objective (104) common to the first detector (100) and the second detector (102) being located at the same optical distance from the first detector (100) and the second detector (102); a directing arrangement (106) configured to direct optical radiation (112) from the common objective (104) to the first detector (100) and the second detector (102) simultaneously or in turns; and a focus device (110) common to the first detector (100) and the second detector (102) being configured to perform a focusing operation for finding a focusing state, where the two-dimensional image captured by the first detector (100) is in focus, and the second detector (102) being configured to capture a single-line image on the basis of the optical radiation directed thereto with said focusing state.

32. 发明公开

EP3326019A1 LICHTBLATTMIKROSKOP ZUM GLEICHZEITIGEN ABBILDEN MEHRERER OBJEKTEBENEN 审中-实审
公开(公告)号：EP3326019A1
公开(公告)日：2018-05-30
申请号：EP16739180.4
申请日：2016-07-18
申请人： Leica Microsystems CMS GmbH
发明人： KNEBEL, Werner , FAHRBACH, Florian
IPC分类号： G02B21/16 , G02B21/36 , G02B21/00
CPC分类号： G02B21/006 , G02B21/0032 , G02B21/16 , G02B21/361 , G02B21/367
摘要： The invention relates to a light sheet microscope comprising a means (60) for simultaneously imaging a plurality of object planes illuminated by means of a light sheet (10) having a detection optics (30) and a camera (50), wherein the object planes are arranged around the focus plane of the detection optics. For simultaneously imaging a plurality of object planes illuminated by means of a light sheet, the microscope preferably comprises a micro lens array (60) in the beam path between the detection optics (30) and the camera (50), which preferably is integrated in the camera (50).

33. 发明公开

EP3255475A3 LASER SCANNING MICROSCOPE, AND LASER SCANNING MICROSCOPE CONTROL METHOD 无效
公开(公告)号：EP3255475A3
公开(公告)日：2018-03-14
申请号：EP17173192.0
申请日：2017-05-29
申请人： Olympus Corporation
发明人： TAMANO, Shingo , HOSONO, Kazuhiko
IPC分类号： G02B19/00 , G02B21/00 , G02B5/00 , G02B5/02
CPC分类号： G02B21/0048 , G01N21/64 , G01N21/6458 , G01N2201/06 , G01N2201/06113 , G02B5/02 , G02B19/0085 , G02B21/0032 , G02B21/006 , G02B21/0064 , G02B21/0076 , G02B21/008 , G02B21/0088 , G02B21/086 , G02B21/16 , G02B21/367
摘要： A laser scanning microscope (100; 200; 300; 400; 500; 600; 700) includes: an objective (5; 5a; 5b) that irradiates a specimen with a laser beam; a detection lens (7) that condenses the laser beam that passes through the specimen, the detection lens (7) being arranged so as to face the objective (5; 5a; 5b); an optical element (8; 26; 27; 28) that is removably arranged between an image plane on which the detection lens (7) forms an image of the specimen and a first surface that is a lens surface closest to the specimen of the detection lens (7), the optical element (8; 26; 27; 28) converting the laser beam made incident on the optical element (8; 26; 27; 28) into diffused light or deflecting a portion of the laser beam made incident on the optical element (8; 26; 27; 28); and a photodetector (12) that detects detection light emitted from the optical element (8; 26; 27; 28) arranged between the image plane and the first surface to the image plane.

34. 发明公开

EP3276388A1 LIGHT SHEET MICROSCOPE AND CONTROL METHOD OF LIGHT SHEET MICROSCOPE 审中-公开
标题翻译：薄片显微镜及薄片显微镜控制方法
公开(公告)号：EP3276388A1
公开(公告)日：2018-01-31
申请号：EP17181645.7
申请日：2017-07-17
申请人： Olympus Corporation
发明人： SHIMADA, Yoshihiro
IPC分类号： G02B21/00 , G02B21/24 , G02B21/36 , G02B27/00
CPC分类号： G02B21/006 , G02B5/005 , G02B15/14 , G02B21/0004 , G02B21/0032 , G02B21/241 , G02B21/245 , G02B21/365 , G02B21/367 , G02B27/0025
摘要： A light sheet microscope (100; 200) includes an objective (7), an illumination optical system (4), a correction device (18, 31), an image pickup device (12), first adjustment means (8), second adjustment means (6) and a controller (20; 40). The controller (20; 40) performs a first focus process and a spherical aberration correction process. The first focus process is a process in which the first adjustment means (8) is controlled on the basis of light that is from the light sheet plane and that is detected via the objective so that the light sheet plane and a focal plane of the objective become closer when a relative position between the light sheet plane and a sample has been changed. The spherical aberration correction process is process in which the correction device is controlled so that an evaluation value of the image of the sample obtained by the image pickup device becomes greater when the first adjustment means (8) has changed the relative position between the light sheet plane and the objective.
摘要翻译：一种光学片显微镜（100; 200），包括物镜（7），照明光学系统（4），校正装置（18,31），图像拾取装置（12），第一调整装置（8），第二调整装置装置（6）和控制器（20; 40）。控制器（20; 40）执行第一聚焦处理和球面像差校正处理。第一聚焦过程是这样的过程，其中基于来自光片平面并且经由物镜检测到的光来控制第一调节装置（8），使得光片平面和物镜的焦平面当光片平面和样品之间的相对位置已经改变时，它们变得更近。球面像差校正处理是这样的处理，其中控制校正装置，使得当第一调整装置（8）已经改变光片之间的相对位置时，由图像拾取装置获得的样本的图像的评估值变得更大飞机和目标。

35. 发明公开

EP3259579A2 SCANNING INFRARED MEASUREMENT SYSTEM 无效转让
标题翻译：扫描红外测量系统
公开(公告)号：EP3259579A2
公开(公告)日：2017-12-27
申请号：EP16723498.8
申请日：2016-02-19
申请人： Premium Genetics (UK) Limited
发明人： MATTHIAS, Wagner
IPC分类号： G01N21/3577 , G01N21/39 , G01N21/53
CPC分类号： G01N15/1436 , G01N15/00 , G01N15/06 , G01N15/1434 , G01N15/147 , G01N15/1475 , G01N21/35 , G01N21/3577 , G01N21/3581 , G01N21/39 , G01N21/53 , G01N21/552 , G01N2015/0065 , G01N2015/0687 , G01N2015/0693 , G01N2015/1006 , G01N2015/1443 , G01N2015/1447 , G01N2015/1488 , G01N2015/1497 , G01N2021/399 , G01N2201/068 , G01N2201/105 , G02B21/0032 , G02B21/0036 , G02B21/006 , G02B21/0064 , G02B21/008
摘要： An analyzer of a component in a sample fluid includes an optical source and an optical detector defining a beam path of a beam, wherein the optical source emits the beam and the optical detector measures the beam after partial absorption by the sample fluid, a fluid flow cell disposed on the beam path defining an interrogation region in the a fluid flow cell in which the optical beam interacts with the sample fluid and a reference fluid; and wherein the sample fluid and the reference fluid are in laminar flow, and a scanning system that scans the beam relative to the laminar flow within the fluid flow cell, wherein the scanning system scans the beam relative to both the sample fluid and the reference fluid.

36. 发明公开

EP3244249A2 LICHTBLATTMIKROSKOP SOWIE VERFAHREN ZUM BETREIBEN EINES LICHTBLATTMIKROSKOPS 有权
公开(公告)号：EP3244249A2
公开(公告)日：2017-11-15
申请号：EP17161551.1
申请日：2017-03-17
申请人： Carl Zeiss Microscopy GmbH
发明人： SIEBENMORGEN, Jörg , LIPPERT, Helmut , KALKBRENNER, Thomas
IPC分类号： G02B21/00 , G02B21/02 , G02B21/06 , G02B21/36
CPC分类号： G02B21/14 , G02B5/0221 , G02B21/0032 , G02B21/0036 , G02B21/006 , G02B21/008 , G02B21/0092 , G02B21/02 , G02B21/06 , G02B21/10 , G02B21/367
摘要： Die Erfindung betrifft ein Mikroskop (1) umfassend ein zur Erzeugung eines Lichtblatts (6) ausgebildetes Beleuchtungsobjektiv (2) mit einer ersten optischen Achse (A1) und ein zur Detektion von aus der Probenebene (4) kommenden Lichts ausgebildetes Detektionsobjektiv (3) mit einer zweiten optischen Achse (A2). Das Beleuchtungsobjektiv (2) und das Detektionsobjektiv (3) sind derart zueinander und zur Probenebene (4) ausgerichtet, dass sich die erste optische Achse (A1) und die zweite optische Achse (A2) in der Probenebene (4) schneiden und miteinander einen im Wesentlichen rechten Winkel einschließen. Die optischen Achsen (A1, A2) schließen mit einer orthogonal zur Probenebene (4) gerichteten Bezugsachse (B) jeweils einen von Null verschiedenen Winkel ein. Ferner ist eine zur Weitfeld-Beleuchtung der Probenebene (4) ausgebildete Übersichtsbeleuchtungsvorrichtung aufweisend eine Beleuchtungsoptik (9) mit einer dritten optischen Achse (A3) vorhanden. Kennzeichnend ist, dass das Detektionsobjektiv (3) zur Detektion sowohl von Licht des Lichtblatts (6) als auch von Licht der Beleuchtungsoptik (9) vorgesehen und ausgebildet ist.
Die Erfindung betrifft weiterhin ein Verfahren zum Betreiben eines Lichtblattmikroskops.

37. 发明公开

EP3234680A1 RASTERMIKROSKOP 审中-公开
公开(公告)号：EP3234680A1
公开(公告)日：2017-10-25
申请号：EP15817826.9
申请日：2015-12-21
申请人： Leica Microsystems CMS GmbH
发明人： FÖLLING, Jonas
IPC分类号： G02B21/00
CPC分类号： G02B21/006 , G02B21/0044 , G02B21/0064 , G02B21/0076 , G02B21/0084 , G02B21/361 , G02B21/367
摘要： The invention relates to a scanning microscope (100), comprising an objective (112) which focuses an illumination beam (102) at a specimen (115), a scanning element (104), which is arranged upstream of the objective (112) and which can be adjusted in order to deflect the illumination beam (102) in a time-varying manner in order to guide the focused illumination beam (102) across the specimen (115) in a scanning motion, and an image sensor (122), onto which the objective (112) focuses a detection beam (114) originating at the specimen (115) illuminated with the focused illumination beam (102). The image sensor (122) has a plurality of sensor elements (124) which can be individually read out by a controller (126) and across which the detection beam (114) is guided in a motion corresponding to the scanning motion of the focused illumination beam (102). A dispersive element (120) of predetermined dispersion effect is provided, which spatially separates different spectral components of the detection beam (114) from each other on the image sensor (122). The controller (126) senses the time-varying adjustment of the scanning element (104), assigns the spectral components of the detection beam (114) to the sensor elements (124) of the image sensor (122) in accordance with said adjustment while taking into account the predetermined dispersion effect of the dispersive element (120), and reads out the sensor elements (124) assigned to the respective spectral components.
摘要翻译：本发明涉及一种扫描显微镜（100），其包括将照明光束（102）聚焦在样本（115）处的物镜（112），布置在物镜（112）上游的扫描元件（104）和为了在扫描运动中引导聚焦的照明光束（102）越过样本（115），可以调整所述照明光束（102）以便以时变方式偏转照明光束（102），以及图像传感器（122）物镜（112）在其上聚焦检测光束（114），该检测光束源于用聚焦照明光束（102）照射的样本（115）。图像传感器（122）具有多个传感器元件（124），所述多个传感器元件能够由控制器（126）单独地读出并且以与聚焦照明的扫描运动对应的运动引导检测束（114）梁（102）。提供预定分散效应的色散元件（120），其在图像传感器（122）上在空间上将检测光束（114）的不同光谱分量彼此分开。控制器（126）感测扫描元件（104）的时变调节，根据所述调节将检测光束（114）的光谱分量分配给图像传感器（122）的传感器元件（124），同时考虑色散元件（120）的预定分散效应，并且读出分配给各个光谱分量的传感器元件（124）。

38. 发明授权

EP1744194B1 Laser scanning microscope and image acquiring method of laser scanning microscope 有权
标题翻译：激光扫描显微镜和激光扫描显微镜图像获取方法
公开(公告)号：EP1744194B1
公开(公告)日：2017-05-10
申请号：EP06014362.5
申请日：2006-07-11
申请人： Olympus Corporation
发明人： RI, Sei
IPC分类号： G02B21/00
CPC分类号： G02B21/006 , G02B21/0064

39. 发明公开

EP3087423A1 MULTI-FOCI MULTIPHOTON IMAGING SYSTEMS AND METHODS 审中-实审
标题翻译：多功能多功能多功能一体机
公开(公告)号：EP3087423A1
公开(公告)日：2016-11-02
申请号：EP14833432.9
申请日：2014-12-24
申请人： Tissuevision, Inc.
发明人： RAGAN, Timothy , YEW, Elijah
IPC分类号： G02B21/00 , G01N21/64
CPC分类号： G01N21/6458 , G01J1/44 , G01J2001/442 , G01J2001/4453 , G01N1/06 , G01N21/6486 , G02B21/0032 , G02B21/004 , G02B21/0048 , G02B21/006 , G02B21/0076 , G02B21/0096 , G02B21/361 , G02B2207/114
摘要： Multi-foci multiphoton imaging systems and methods are provided herein which advantageously implement an excitation system that avoids aberrations and a restricted field of view while utilizing a non-descanned detection system with interlaced scanning that reduces crosstalk and provides for improved imaging of tissue. The non-descanned detection system can employ a high-efficiency fiber coupled detection.
摘要翻译：本文提供多焦点多光子成像系统和方法，其有利地实现避免像差和受限视场的激励系统，同时利用具有减少串扰并提供组织改进成像的隔行扫描的非下行检测系统。非下行检测系统可以采用高效光纤耦合检测。

40. 发明授权

EP2618197B1 3-DIMENSIONAL CONFOCAL MICROSCOPY APPARATUS AND FOCAL PLANE SCANNING AND ABERRATION CORRECTION UNIT 有权
标题翻译： FOR焦点转变级别和像差校正3维共聚焦显微镜和设备
公开(公告)号：EP2618197B1
公开(公告)日：2016-06-08
申请号：EP11824911.9
申请日：2011-07-27
申请人： Japan Science and Technology Agency
发明人： IKUTA, Koji , IKEUCHI, Masashi
IPC分类号： G02B21/00 , G02B21/32 , G02B21/36
CPC分类号： G02B21/367 , B33Y80/00 , G02B21/006 , G02B21/0076 , G02B21/32 , G02B21/365
摘要： Provided is a 3-dimensional confocal microscopy apparatus which is manufactured by combining a confocal microscope and an optical tweezers technique, wherein a pair of lenses for focal plane displacement where one lens is movable in the optical axis direction is arranged between a fixed objective lens and a fluorescent light imaging camera, and the 3-dimensional confocal microscopy apparatus also includes a mean which corrects the aberration of a fluorescent confocal image obtained by the fluorescent imaging camera. Accordingly, it is possible to provide a 3-dimensional confocal microscopy apparatus which can acquire a 3-dimensional image of a specimen during a manipulation of the specimen using optical tweezers without affecting an optical trap.
摘要翻译：本发明提供一种三维共聚焦显微镜装置的所有其通过结合共焦显微镜和光学镊子技术制造，worin一对透镜焦平面位移，其中一个透镜是在光轴方向上移动是一个固定物镜和之间布置因此荧光灯成像相机和所述三维共聚焦显微镜装置包括：平均校正因荧光成像相机获得的荧光的共焦图像的像差。因此，有可能提供一种三维共聚焦显微镜装置使用光学镊子试样的操作，在此期间能够获得的试样的3维图像，而不会影响到光阱。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式