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11. 发明公开

EP1925937A1 Method for assaying antigen related to disorders caused by mental stress 失效
标题翻译：引起的精神压力与疾病相关的抗原的检测方法
公开(公告)号：EP1925937A1
公开(公告)日：2008-05-28
申请号：EP08000214.0
申请日：1996-09-25
申请人： Suntory Limited
发明人： Inui, Takako , Nakagawa, Masashi , Terano, Yoshitake , Ozaki, Mamiko
IPC分类号： G01N33/53 , G01N33/68 , C07K14/47
CPC分类号： G01N33/6893 , C07K14/47 , Y10S436/811
摘要： The invention relates to the development of a method for assaying an antigen which is associated with disorders caused by mental stress in a human body fluid by way of an immunoassay technique which utilizes an antibody against a mental stress related protein having the following properties or a fragment thereof:
(1) having a molecular weight of about 14 kDa (measured by SDS-PAGE); and
(2) having the N-terminal partial sequence represented by SEQ ID NO: 1; and a kit for diagnosing disorders caused by mental stress which contains the above-mentioned antibody or a fragment thereof. Thus, the accumulation of mental stress can be easily estimated and judged and the results can be applied to the diagnosis of disorders caused by mental stress.
摘要翻译：本发明涉及的方法的发展，为的化验抗原所有其通过免疫测定技术，其利用抗体对具有下列性能或片段的精神压力相关蛋白的方式与在人体液由精神压力引起的疾病相关的物：（1）具有约14千道尔顿（通过SDS-PAGE测得）的分子量; 和（2）具有由SEQ ID NO所代表的N-末端部分序列：1; 和用于诊断由其中含有上述的抗体或其片段的精神压力引起的病症的试剂盒。因此，精神压力的累积可以被估计，并且容易地判断，其结果可应用于精神压力引起的病症的诊断。

12. 发明公开

EP1919936A2 GLYCEROL CHANNEL GENE AND USE THEREOF 审中-公开
标题翻译：甘草通道基因及其用途
公开(公告)号：EP1919936A2
公开(公告)日：2008-05-14
申请号：EP06797578.9
申请日：2006-08-31
申请人： SUNTORY LIMITED
发明人： NAKAO, Yoshihiro , KODAMA, Yukiko , SHIMONAGA, Tomoko
IPC分类号： C07K14/395
CPC分类号： C07K14/395 , C12C12/004 , C12C12/006 , C12G1/0203 , C12G3/02
摘要： The present invention relates to a glycerol channel gene and its uses, specifically, a brewery yeast producing alcoholic beverages with excellent body and mellowness, alcoholic beverages produced using the yeast, a process for producing the alcoholic beverages. More particularly, the present invention relates to a yeast whose capability of producing glycerol, which contribute to body and mellowness of products, was controlled by controlling expression level of FPS1 gene encoding brewery yeast glycerol channel Fps1p, particularly non-ScFPS1 gene specific to lager brewing yeast, and to a method for producing alcoholic beverages with the yeast.
摘要翻译：本发明涉及甘油通道基因及其用途，具体而言，涉及生产具有优异的身体和醇味的酒精饮料的啤酒酵母，使用该酵母生产的酒精饮料，以及用于生产酒精饮料的方法。更具体地说，本发明涉及通过控制编码啤酒酵母甘油通道Fps1p，特别是啤酒酵母特异性非ScFPS1基因的FPS1基因的表达水平来控制产生有助于产品的身体和醇味的甘油的能力的酵母酵母，以及用该酵母生产酒精饮料的方法。

13. 发明公开

EP1913022A1 DIHYDROXY-ACID DEHYDRATASE GENE AND USE THEREOF 审中-公开
标题翻译：二羟酸及其用途DEHYDRATASEGEN
公开(公告)号：EP1913022A1
公开(公告)日：2008-04-23
申请号：EP06796517.8
申请日：2006-08-11
申请人： SUNTORY LIMITED
发明人： NAKAO, Yoshihiro c/o SUNTORY LIMITED, Research Center , KODAMA, Yukiko c/o SUNTORY LIMITED, Research Center , SHIMONAGA, Tomoko c/o SUNTORY LIMITED, Research Center
IPC分类号： C07K14/435
CPC分类号： C12N9/88
摘要： The present invention relates to an dihydroxy-acid dehydratase gene and use thereof, in particular, a brewery yeast for producing alcoholic beverages having superior flavor, alcoholic beverages produced with said yeast, and a method for producing said beverages. More particularly, the present invention relates to a yeast whose level of producing total vicinal diketones, especially level of producing diacetyl, that are responsible off-flavor of the product, is reduced by amplifying the expression level of ILV3 gene encoding brewery yeast dihydroxy-acid dehydratase ILV3p, particularly non-ScILV3 gene specific to lager brewing yeast, and to a method for producing alcoholic beverages with said yeast.

14. 发明公开

EP1905729A1 Filling method, filling device and container 有权
标题翻译： FüllverfahrenundFüllvorrichtungfürFässer
公开(公告)号：EP1905729A1
公开(公告)日：2008-04-02
申请号：EP07253779.8
申请日：2007-09-24
申请人： SUNTORY LIMITED
发明人： Horikoshi, Takayoshi
IPC分类号： B67C3/30
CPC分类号： B67C3/30
摘要： A filling device (10) includes: a liquid filling means (21) for filling a predetermined filling weight of a liquid into a container (40); and a temperature measurement means (24) for measuring a temperature of the liquid filled by the liquid filling means. In the filling device, in a case where a measured temperature of the liquid measured by the temperature measurement means is higher than a predetermined value, a filling speed of filling the liquid from the liquid filling means is reduced according to the measured temperature. Due to this, foaming action of beer can be suppressed without requiring a large volume of inert gas. It is preferable to reduce the filling speed of filling the liquid by a liquid control valve (26), which is arranged in a supply pipe line, and/or a pre-stress gas control valve (57).
摘要翻译：一种填充装置（10）包括：用于将预定填充重量的液体填充到容器（40）中的液体填充装置（21）; 以及用于测量由液体填充装置填充的液体的温度的温度测量装置（24）。在填充装置中，在由温度测量装置测量的液体的测量温度高于预定值的情况下，根据测量的温度减少从液体填充装置填充液体的填充速度。由此，可以抑制啤酒的发泡作用，而不需要大量的惰性气体。优选的是，通过布置在供给管线中的液体控制阀（26）和/或预应力气体控制阀（57）来降低填充液体的填充速度。

15. 发明公开

EP1896844A1 METHOD FOR PROCYANIDIN ANALYSIS 有权
标题翻译：原花青素分析程序
公开(公告)号：EP1896844A1
公开(公告)日：2008-03-12
申请号：EP06780775.0
申请日：2006-06-28
申请人： SUNTORY LIMITED
发明人： FUKUI, Yuko
IPC分类号： G01N33/14
CPC分类号： G01N33/14 , G01N2030/8813 , Y10T436/142222
摘要： The present invention relates to a novel method for quantifying procyanidin and flavan-3-ols contained in natural products, foods and drinks, pharmaceuticals and/or cosmetics. The present invention provides a method for quantifying procyanidin (a generic name for a mixture of catechin n-mer; n ≥ 1) contained in test samples such as natural products, foods and drinks, pharmaceuticals and/or cosmetics, which comprises a) pretreating a test sample using a column to remove contaminants which affect the analysis of procyanidin and flavan-3-ol; and b) effecting high performance liquid chromatography (HPLC) to separate and quantify procyanidin and flavan-3-ols in the solution treated to remove contaminants during the above pretreatment step a).

16. 发明授权

EP1670905B1 A GENE ENCODING AN ENZYME FOR CATALYZING BIOSYNTHESIS OF LIGNAN, AND USE THEREOF 有权
标题翻译： FOR A用于催化LIGNANBIOSYNTHESE编码基因及其用途酶
公开(公告)号：EP1670905B1
公开(公告)日：2008-03-12
申请号：EP04773621.0
申请日：2004-09-29
申请人： SUNTORY LIMITED
发明人： ONO, Eiichiro , TANAKA, Yoshikazu
IPC分类号： C12N9/04 , C12N15/82 , C12P7/22 , A01H5/00
CPC分类号： C12P17/181 , C12N9/0071 , C12N15/8243

17. 发明授权

EP1406091B1 METHOD OF ANALYZING PROTEIN OCCURRING IN CELL OR SUBSTANCE INTERACTING WITH THE PROTEIN 有权
标题翻译：程序对蛋白质在细胞中的分析发生的或与蛋白质互动物质
公开(公告)号：EP1406091B1
公开(公告)日：2008-02-20
申请号：EP02738766.1
申请日：2002-06-19
申请人： SUNTORY LIMITED
发明人： NAKAJIMA, Terumi , NAOKI, Hideo , YASUDA, Akikazu , IWASA, Keiko
IPC分类号： G01N33/566 , G01N33/483 , G01N30/72 , G01N27/62 , G01N33/68 , G01N33/50
CPC分类号： C40B30/04 , G01N33/5008 , G01N33/502 , G01N33/5082 , G01N33/566 , G01N33/6803 , G01N33/6845 , G01N2500/00 , G01N2500/20
摘要： A method which comprises: bringing cells having a protein into contact with a substance interacting with the protein to thereby make them to interact; purifying the cells as being under the interaction with the substance; irradiating the purified cells with laser to thereby directly ionize the substance; and analyzing the thus ionized substance by mass spectrometry. Using this method, the molecular weight, molecular chemical species and molecular structure of a protein occurring in cell surface layer or in cells or a substance interacting with the protein can be easily identified or analyzed within a short time. The above method is a novel method of screening a substance interacting with a protein occurring in cells without resort to the conventional bioassay methods. Also, it is a novel method of judging the presence of a specific protein in cells with the use of a substance interacting with the protein. Moreover, these methods can be conveniently performed and enable accurate and quick judgment.

18. 发明公开

EP1879915A1 GENE ENCODING GLYCOGEN SYNTHESIS INITIATOR AND USE THEREOF 有权
标题翻译： GEN CODING发起者糖原合成及其用途
公开(公告)号：EP1879915A1
公开(公告)日：2008-01-23
申请号：EP07715033.2
申请日：2007-02-21
申请人： SUNTORY LIMITED
发明人： NAKAO, Yoshihiro , KODAMA, Yukiko , SHIMONAGA, Tomoko
IPC分类号： C07K14/395
CPC分类号： C07K14/395
摘要： The present invention relates to a gene encoding glycogen synthesis initiator and use thereof, in particular, a yeast for practical use with superior resistance property to dryness and/or low-temperature storage, alcoholic beverages produced with said yeast, and a method for producing said beverages. More particularly, the present invention relates to a yeast, whose resistance property to dryness and/or resistance property to low-temperature storage is enhanced by amplifying expression level of GLG1 or GLG2 gene encoding a Glg1p or Glg2p which is a glycogen synthesis initiator in brewer's yeast, especially non-ScGLG1 gene or non-ScGLG2 gene specific to a lager brewing yeast and to a method for producing alcoholic beverages with said yeast, etc.

19. 发明公开

EP1877552A2 O-ACETYLHOMOSERINESULFHYDORELACE GENE AND USE THEREOF 有权
标题翻译： O-乙酰高丝氨酸 - 丝氨酸基因及其用途
公开(公告)号：EP1877552A2
公开(公告)日：2008-01-16
申请号：EP06796825.5
申请日：2006-08-21
申请人： SUNTORY LIMITED
发明人： NAKAO, Yoshihiro , KODAMA, Yukiko , SHIMONAGA, Tomoko
IPC分类号： C12N9/88 , C12N15/09 , C12N15/81 , C12C11/00 , C12C11/02
CPC分类号： C12C12/006 , C12C12/004 , C12G1/0203 , C12N9/1085
摘要： The present invention relates to a brewery yeast having controlled hydrogen sulfide-producing capability, a process for producing alcoholic beverages with controlled hydrogen sulfide amount. More particularly, the present invention relates to a yeast whose hydrogen sulfide-producing capability that increases the product flavor is controlled by enhancing the expression level of MET17 gene encoding brewery yeast O-acetylhomoserinesulfhydorelace Met17p, particularly non-ScMET17 gene specific to lager brewing yeast, and to a method for producing alcoholic beverages with said yeast.
摘要翻译：本发明涉及具有受控制的硫化氢生产能力的啤酒酵母，生产具有受控硫化氢量的酒精饮料的方法。更具体地，本发明涉及通过增强编码啤酒酵母O-乙酰高丝氨酸巯基乙酸酯Met17p，特别是啤酒酵母特异性非ScMET17基因的MET17基因的表达水平来控制增加产品风味的产生硫化氢能力的酵母，并涉及用所述酵母生产酒精饮料的方法。

20. 发明公开

EP1869072A1 GENE ENCODING PROTEIN RESPONSIBLE FOR FLOCCULATION PROPERTY OF YEAST AND USE THEREOF 有权
标题翻译： GEN WHAT FOR所编码的蛋白质，对于FLOCKULIERUNGSEIGENSCHAFTEN酵母负责及其用途
公开(公告)号：EP1869072A1
公开(公告)日：2007-12-26
申请号：EP06843768.0
申请日：2006-12-27
申请人： SUNTORY LIMITED
发明人： NAKAO, Yoshihiro , KODAMA, Yukiko , SHIMONAGA, Tomoko
IPC分类号： C07K14/395
CPC分类号： C07K14/395
摘要： The present invention relates to a gene encoding a protein responsible for flocculation property of yeast and use thereof, in particular, a brewery yeast with appropriate flocculation property for producing desired alcoholic beverages, alcoholic beverages produced with said yeast, and a method for producing said beverages. More particularly, the present invention relates to a yeast to which suitable flocculation property for brewing desired alcoholic beverages was imparted by controlling expression level of MHP1 gene encoding a protein responsible for flocculation property of brewery yeast, especially non-ScMHP1 gene specific to a lager brewing yeast, to alcoholic beverages produced with said yeast and to a method for producing said beverages.

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