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    • 1. 发明公开
    • Method for assaying antigen related to disorders caused by mental stress
    • 引起的精神压力与疾病相关的抗原的检测方法
    • EP1925937A1
    • 2008-05-28
    • EP08000214.0
    • 1996-09-25
    • Suntory Limited
    • Inui, TakakoNakagawa, MasashiTerano, YoshitakeOzaki, Mamiko
    • G01N33/53G01N33/68C07K14/47
    • G01N33/6893C07K14/47Y10S436/811
    • The invention relates to the development of a method for assaying an antigen which is associated with disorders caused by mental stress in a human body fluid by way of an immunoassay technique which utilizes an antibody against a mental stress related protein having the following properties or a fragment thereof:
      (1) having a molecular weight of about 14 kDa (measured by SDS-PAGE); and
      (2) having the N-terminal partial sequence represented by SEQ ID NO: 1; and a kit for diagnosing disorders caused by mental stress which contains the above-mentioned antibody or a fragment thereof. Thus, the accumulation of mental stress can be easily estimated and judged and the results can be applied to the diagnosis of disorders caused by mental stress.
    • 本发明涉及的方法的发展,为的化验抗原所有其通过免疫测定技术,其利用抗体对具有下列性能或片段的精神压力相关蛋白的方式与在人体液由精神压力引起的疾病相关的 物:(1)具有约14千道尔顿(通过SDS-PAGE测得)的分子量; 和(2)具有由SEQ ID NO所代表的N-末端部分序列:1; 和用于诊断由其中含有上述的抗体或其片段的精神压力引起的病症的试剂盒。 因此,精神压力的累积可以被估计,并且容易地判断,其结果可应用于精神压力引起的病症的诊断。