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1. 发明申请

US20070167486A1 Novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same 失效
标题翻译：新的2-氧杂环化合物和包含它们的药物组合物
公开(公告)号：US20070167486A1
公开(公告)日：2007-07-19
申请号：US10557085
申请日：2004-05-17
申请人： Yung Kho , Gyoon Han , Ho Lee , Bum Park , Hyo Chun , Hwan Kim , Song Park , Sang Han , Dong Ryu , Tae Chun , Jin Lee , Chang Lee , Ki Lee , Hee Lee
发明人： Yung Kho , Gyoon Han , Ho Lee , Bum Park , Hyo Chun , Hwan Kim , Song Park , Sang Han , Dong Ryu , Tae Chun , Jin Lee , Chang Lee , Ki Lee , Hee Lee
IPC分类号： A61K31/4545 , A61K31/445 , A61K31/454 , C07D401/02
CPC分类号： C07D207/26 , C07D207/38 , C07D211/86 , C07D409/06
摘要： The present invention is related to new 2-oxo-cyclic compound the process for preparing them and a pharmaceutical composition comprising the same. The present invention provides a pharmaceutical composition for preventing and treating the inflammatory disease comprising the pain or inflammation caused by rheumatic disease, for example, rheumatoid arthritis, spondyloarthopathies, gout, osteoarthritis, systemic lupus erythematosus and juvenile arthritis, and inflammatory syndrome for example, from myositis, gingivitis, synovitis, ankylosing spondylitis, burstitis, burns and scar, inflammatory Crohn's disease, Types I diabetes. therefore, it can be used as the therapeutics for treating and preventing inflammatory diseases.
摘要翻译：本发明涉及新的2-氧代环状化合物及其制备方法和包含其的药物组合物。本发明提供了用于预防和治疗炎性疾病的药物组合物，其包括由风湿性疾病引起的疼痛或炎症，例如类风湿性关节炎，脊椎动物病变，痛风，骨关节炎，系统性红斑狼疮和幼年关节炎以及炎性综合征，例如，肌炎，牙龈炎，滑膜炎，强直性脊柱炎，爆发性炎症，烧伤和瘢痕，炎性克罗恩病，I型糖尿病。因此，它可以用作治疗和预防炎性疾病的治疗剂。

2. 发明申请

US20060173043A1 Use of novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same 失效
标题翻译：新型2-氧杂环化合物的用途及其组合物
公开(公告)号：US20060173043A1
公开(公告)日：2006-08-03
申请号：US10564653
申请日：2004-07-15
申请人： Gyoon Han , Hwan Kim , Song Park , Chang-Woo Lee , Sang Han , Ki Lee , Yung Kho , Jin Yang , Bum Park , Hyang Lee , Jeung Han , Dong Ryu , Jin Lee , Tae Chun , Yong Kim , Hee Lee , Bong Lee , Jeom Kim , Ji Kim , Kyunga Yu , Sun Kim
发明人： Gyoon Han , Hwan Kim , Song Park , Chang-Woo Lee , Sang Han , Ki Lee , Yung Kho , Jin Yang , Bum Park , Hyang Lee , Jeung Han , Dong Ryu , Jin Lee , Tae Chun , Yong Kim , Hee Lee , Bong Lee , Jeom Kim , Ji Kim , Kyunga Yu , Sun Kim
IPC分类号： A61K31/4545 , A61K31/454
CPC分类号： A61K31/454 , A61K31/4015 , A61K31/4545 , C07D207/38 , C07D211/86 , C07D223/10 , C07D417/06
摘要： The present invention is related to novel use of 2-oxo-heterocyclic compounds having anticancer activity and the process for preparing them and a pharmaceutical composition comprising the same. The present invention provides a pharmaceutical composition for preventing and treating the cancer disease comprising lung cancer, bone cancer, pancreatic cancer, skin cancer, cancer of the head and neck, cutaneous or intraocular melanoma, uterine cancer, ovarian cancer, rectal cancer or cancer of the anal region, stomach cancer, colon cancer, breast cancer, gynecologic tumors, Hodgkin's disease, cancer of the esophagus, cancer of the small intestine, cancer of the endocrine system, sarcomas of soft tissues, cancer of the urethra, cancer of the penis, prostate cancer, chronic or acute leukemia, solid tumors of childhood, lymphocytic lymphonas, cancer of the bladder, cancer of the kidney or ureter, or neoplasms of the central nervous system, therefore, it can be used as the therapeutics for treating and preventing cancer diseases.
摘要翻译：本发明涉及具有抗癌活性的2-氧代杂环化合物及其制备方法的新用途以及包含其的药物组合物。本发明提供了用于预防和治疗包括肺癌，骨癌，胰腺癌，皮肤癌，头颈癌，皮肤或眼内黑素瘤，子宫癌，卵巢癌，直肠癌或癌症的癌症疾病的药物组合物肛门区域，胃癌，结肠癌，乳腺癌，妇科肿瘤，霍奇金病，食道癌，小肠癌，内分泌系统癌，软组织肉瘤，尿道癌，阴茎癌，前列腺癌，慢性或急性白血病，儿童实体瘤，淋巴细胞淋巴管，膀胱癌，肾或输尿管癌，或中枢神经系统肿瘤，因此可用作治疗和预防的治疗剂癌症疾病

3. 发明申请

US20070181667A1 Automated teller machine having a cassette apparatus 有权
标题翻译：具有盒装置的自动柜员机
公开(公告)号：US20070181667A1
公开(公告)日：2007-08-09
申请号：US11475133
申请日：2006-06-27
申请人： Jae Kwak , Woo Lee , Hee Lee , Joon Yoon
发明人： Jae Kwak , Woo Lee , Hee Lee , Joon Yoon
IPC分类号： G07F19/00
CPC分类号： G07F19/201 , B65H29/46 , B65H31/22 , B65H2701/1912 , G07D7/04 , G07D11/0012 , G07F19/20
摘要： An automatic teller machine (ATM) has a cassette apparatus, detachably accommodated in a cassette accommodating space of the ATM, for storing the cheques endorsed by a printing unit therein. The cassette apparatus includes a storage cassette for stacking the cheques in a cheque storage position thereof, a transfer unit for transferring the cheques provided thereto, a cassette driving unit for driving the transfer unit when the storage cassette is accommodated into the cassette accommodating space, and a stacking unit installed in the cassette accommodating space for taking out the cheques transferred to a designated position and stacking the cheques on the cheque storage position.
摘要翻译：自动取款机（ATM）具有盒式装置，可拆卸地容纳在ATM的盒容纳空间中，用于存储由印刷单元支持的支票。盒式磁带设备包括用于将检查堆放在其检查存储位置的存储盒，用于传送提供的检查的传送单元，当存储盒被容纳在盒容纳空间中时用于驱动传送单元的盒驱动单元，以及安装在盒容纳空间中用于取出转移到指定位置的支票并将支票堆积在支票存储位置的堆垛单元。

4. 发明申请

US20060126586A1 Wireless LAN device and method of monitoring status of wireless LAN 审中-公开
标题翻译：无线局域网设备及无线局域网状态监控方法
公开(公告)号：US20060126586A1
公开(公告)日：2006-06-15
申请号：US11281367
申请日：2005-11-18
申请人： Soung Um , Dong Kwak , Hyeon Cho , Dong Hahn , Hee Lee , Min Hwang
发明人： Soung Um , Dong Kwak , Hyeon Cho , Dong Hahn , Hee Lee , Min Hwang
IPC分类号： H04Q7/24
CPC分类号： H04W24/00 , H04L1/0014 , H04L1/0015 , H04L1/0026 , H04L1/20 , H04W84/12
摘要： A wireless LAN device and a method of monitoring the status of a wireless LAN are disclosed. The wireless LAN device according to the present invention can determine the status of a wireless LAN using a variety of information obtained by performing media access control (MAC) without additional packet transmission/reception with a correspondent wireless LAN device. Accordingly, if the wireless LAN device of the present invention is various kinds of wireless A/V (Audio/Video) devices that provide the A/V streaming, the data transmission can be optimally made in accordance with the status of the monitored wireless LAN. Further, since there is no additional communication needed to monitor the status of a wireless LAN, the present invention has advantages in that the processing speed of the wireless LAN device is improved and the traffic of the wireless LAN is not increased.
摘要翻译：公开了一种无线LAN设备和监视无线LAN的状态的方法。根据本发明的无线LAN设备可以使用通过执行媒体访问控制（MAC）获得的各种信息来确定无线LAN的状态，而无需对通信无线LAN设备的附加分组发送/接收。因此，如果本发明的无线LAN设备是提供A / V流传输的各种无线A / V（音频/视频）设备，则可以根据所监视的无线LAN的状态来最佳地进行数据传输。此外，由于不需要额外的通信来监视无线LAN的状态，因此本发明的优点在于，提高了无线LAN设备的处理速度，并且无法增加无线LAN的流量。

5. 发明申请

US20060098492A1 Erase-verifying method of NAND type flash memory device and NAND type flash memory device thereof 审中-公开
标题翻译： NAND型闪存器件及其NAND型闪存器件的擦除验证方法
公开(公告)号：US20060098492A1
公开(公告)日：2006-05-11
申请号：US11126321
申请日：2005-05-11
申请人： Hee Lee
发明人： Hee Lee
IPC分类号： G11C16/04
CPC分类号： G11C16/3445 , G11C16/0483 , G11C16/16 , G11C16/344
摘要： An erase-verifying method of a NAND type flash memory device and NAND type flash memory device thereof, wherein an erase-verifying operation is performed by applying a positive voltage as a source voltage. Considering a variation width of a threshold voltage of an erase cell, which shifts due to various factors, a negative threshold voltage of an erase cell can be stably verified. Through this, even when the threshold voltage of the erase cell shifts due to disturbance upon subsequent program operation, the number of cells failed can be reduced.
摘要翻译： NAND型闪存器件及其NAND型闪存器件的擦除验证方法，其中通过施加正电压作为源极电压来执行擦除验证操作。考虑到由于各种因素而移位的擦除单元的阈值电压的变化幅度，可以稳定地验证擦除单元的负阈值电压。由此，即使由于擦除单元的阈值电压由于随后的编程动作引起的干扰而发生移位，也可以减少单元的数量。

6. 发明申请

US20050221449A1 Nucleotide sequence of threonine operon irrepressible by isoleucine and method for producing l-threonine using transformed host cell containing the same 有权
标题翻译：通过异亮氨酸不可抑制的苏氨酸操纵子的核苷酸序列和使用含有该苏氨酸的转化宿主细胞产生1-苏氨酸的方法
公开(公告)号：US20050221449A1
公开(公告)日：2005-10-06
申请号：US10514348
申请日：2003-05-15
申请人： Hee Lee , Seong Kim , Jin Sung , Seok Song , Young Park
发明人： Hee Lee , Seong Kim , Jin Sung , Seok Song , Young Park
IPC分类号： C12N15/70 , C12N15/52 , C12P13/04 , C12N1/21 , C12N9/10 , C12N15/74
CPC分类号： C12N15/52
摘要： A nucleotide sequence of the threonine operon of E. coli with a deletion of all or part of a nucleotide fragment of −56 to −18, a recombinant vector containing the above nucleotide sequence, and a transformed host cell containing the recombinant vector are provided. A method for producing L-threonine comprising culturing the transformed host cell is also provided.
摘要翻译：提供大肠杆菌的苏氨酸操纵子的核苷酸序列，其全部或部分缺失-56至-18的核苷酸片段，含有上述核苷酸序列的重组载体和含有重组载体的转化宿主细胞。还提供了生产L-苏氨酸的方法，包括培养转化的宿主细胞。

7. 发明申请

US20080008839A1 YAG barrier coatings and methods of fabrication 有权
标题翻译： YAG阻挡涂层和制造方法
公开(公告)号：US20080008839A1
公开(公告)日：2008-01-10
申请号：US11253352
申请日：2005-10-19
申请人： Hee Lee , Tai-Il Mah
发明人： Hee Lee , Tai-Il Mah
IPC分类号： B05D1/36 , B05D7/00
CPC分类号： C23C28/321 , C23C28/3215 , C23C28/345 , C23C28/3455 , C23C28/42
摘要： Coated alloys and methods of making coated alloy are provided. The coated alloy comprises a superalloy substrate, a bond coat comprising a metallic alloy disposed on the superalloy substrate, an oxidation barrier coating comprising yttrium aluminum garnet (YAG) disposed on the bond coat, and a top coat defining the outermost layer disposed on the oxidation barrier coating.
摘要翻译：提供涂覆合金和制造涂层合金的方法。涂覆合金包括超合金基底，包含设置在超合金基底上的金属合金的粘合涂层，包含设置在粘合涂层上的钇铝石榴石（YAG）的氧化阻隔涂层和限定设置在氧化物上的最外层的顶涂层阻隔涂层。

8. 发明申请

US20070059363A1 Method of preparing mixed formulation of sustained release microspheres by continuous one-step process 有权
标题翻译：通过连续一步法制备缓释微球混合制剂的方法
公开(公告)号：US20070059363A1
公开(公告)日：2007-03-15
申请号：US10562379
申请日：2004-06-25
申请人： Hee Lee , Sung Kim , Jung Kim , Ji Lee , Young Jung , Jun Kim , Yun Seo , Ho-Il Choi , Seung Chang , Kee Park
发明人： Hee Lee , Sung Kim , Jung Kim , Ji Lee , Young Jung , Jun Kim , Yun Seo , Ho-Il Choi , Seung Chang , Kee Park
IPC分类号： A61K38/17 , A61K9/22
CPC分类号： A61K9/1694 , A61K9/1647 , A61K9/5084 , A61K38/24
摘要： Disclosed is a method for preparing a mixed formulation of sustained release microspheres with various compositions by a continuous one-step process. The present method is characterized by preparing the mixed formulation of sustained release microspheres with different compositions by a continuous one-step process by continuously introducing the mixed fluids into a dryer from the two or more different fluids for preparation of sustained release microspheres containing a biodegradable polymer, a drug, an additive and a solvent with different types of contents or both of the components, by controlling the mixing ratios of the fluids according to the time, unlike a conventional method including spray-drying a mixture of microspheres containing a biodegradable polymer, a drug, an additive and a solvent with a single composition. The present method can achieve a desired drug release, which is difficult to be obtained by conventional microspheres with a single composition, by preparing microspheres by a continuous one-step process, and can simplify the conventional complex process of separately preparing several microsphere formulations and then mixing the formulations at a proper ratio to achieve a desired drug release.
摘要翻译：公开了通过连续一步法制备具有各种组成的缓释微球混合制剂的方法。本发明的方法的特征在于通过连续一步法制备具有不同组成的缓释微球的混合制剂，通过从两种或更多种不同的流体连续引入混合流体到干燥器中，用于制备含有可生物降解聚合物的缓释微球，药物，添加剂和具有不同类型含量的溶剂或两种组分的溶剂通过控制流体的混合比而不同于常规方法，包括喷雾干燥含有可生物降解的聚合物的微球体的混合物，药物，添加剂和具有单一组成的溶剂。本发明方法可以通过连续一步法制备微球，实现通过具有单一组成的常规微球难以获得的所需药物释放，并且可以简化分别制备几种微球制剂的常规复合方法，然后以适当的比例混合制剂以实现期望的药物释放。

9. 发明申请

US20060088122A1 Direct-conversion frequency mixer 有权
标题翻译：直接转换混频器
公开(公告)号：US20060088122A1
公开(公告)日：2006-04-27
申请号：US11226045
申请日：2005-09-14
申请人： Byoung Choi , Seok Hyun , Geum Tak , Hee Lee , Seong-Su Park , Chul Park
发明人： Byoung Choi , Seok Hyun , Geum Tak , Hee Lee , Seong-Su Park , Chul Park
IPC分类号： H04L27/18
CPC分类号： H03D7/1441 , H03D7/1491 , H03D7/165 , H03D2200/0084
摘要： Provided is a direct-conversion frequency mixer for down converting a radio frequency (RF) signal into a baseband signal, in which a single phase RF signal and a quadrature location oscillation (quadrature LO) signal are used to generate the baseband signal, the frequency mixer comprising a first frequency mixing unit that uses quadrature LO signals having respective phases of 0 degrees and 180 degrees to directly down-convert the single phase RF signal into the in-phase baseband signal, and a second frequency mixing unit that uses quadrature LO signals having respective phases of 90 degrees and 270 degrees to directly down-convert the single phase RF signal into the quadrature-phase baseband signal, whereby drains and sources of the transistor for receiving the quadrature LO signaland the transistor for receiving the RF signal are connected in common, thus enabling low power source voltage driving.
摘要翻译：提供了一种用于将射频（RF）信号下变频为基带信号的直接转换混频器，其中使用单相RF信号和正交位置振荡（正交LO）信号来产生基带信号，频率混频器，其包括使用具有0度和180度的相位的正交LO信号的第一频率混合单元，以将单相RF信号直接下变频为同相基带信号;以及第二混频单元，其使用正交LO信号具有90度和270度的各个相位以将单相RF信号直接下变频为正交相位基带信号，由此用于接收正交LO信号的晶体管的漏极和源极以及用于接收RF信号的晶体管被连接在通用，从而实现低电源电压驱动。

10. 发明申请

US20060066526A1 Driving apparatus for organic electro-luminescence display device 失效
公开(公告)号：US20060066526A1
公开(公告)日：2006-03-30
申请号：US11042065
申请日：2005-01-26
申请人： Ji Kim , Hak Kim , Hee Lee
发明人： Ji Kim , Hak Kim , Hee Lee
IPC分类号： G09G3/30
CPC分类号： G09G3/3216 , G09G3/3266 , G09G2320/043 , G09G2330/04
摘要： A driving apparatus for an organic electro-luminescence display device for reducing a deterioration of organic light-emitting diode device in the organic electro-luminescence display device is disclosed. In the driving apparatus, a data supplier supplies a data signal to an anode of an organic light-emitting diode device. A first voltage source generates a first voltage. A second voltage source generates a second voltage higher than said first voltage. A voltage stabilizer stabilizes said second voltage to be supplied to the cathode of the organic light-emitting diode device. First and second switching devices selectively apply said first and second voltages to a cathode of the organic light-emitting diode device.

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