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    • 3. 发明授权
    • Pesticidal compositions
    • 杀虫剂组合物
    • US4694009A
    • 1987-09-15
    • US746432
    • 1985-06-19
    • Adolf HubeleHelmut ZondlerPeter RiebliWolfgang Eckhardt
    • Adolf HubeleHelmut ZondlerPeter RiebliWolfgang Eckhardt
    • A01N43/54C07D239/42C07D239/46C07D239/47C07D239/52A61K31/505
    • C07D239/42A01N43/54C07D239/47
    • The invention discloses novel N-(2-nitrophenyl)-2-aminopyrimidine derivatives of the general formula I ##STR1## wherein R.sub.1 and R.sub.2 are hydrogen, NO.sub.2 or CF.sub.3, with the proviso that only R.sub.1 or R.sub.2 can be NO.sub.2 ;R.sub.4 is hydrogen or the --C(O)R' group, in which R' is C.sub.1 -C.sub.4 alkyl which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkylthio;R.sub.5, R.sub.6 and R.sub.7 are each independently halogen, nitro, cyano, thiocyano, C.sub.1 -C.sub.12 alkyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.1 -C.sub.8 alkylthio, C.sub.1 -C.sub.6 alkylsulfonyl, C.sub.1 -C.sub.6 alkylsulfoxyl, C.sub.3 -C.sub.6 alkenyl, C.sub.3 -C.sub.6 haloalkenyl, C.sub.3 -C.sub.6 alkynyl, C.sub.3 -C.sub.6 haloalkynyl, C.sub.3 -C.sub.6 alkenyloxy, C.sub.3 -C.sub.6 haloalkenyloxy, C.sub.3 -C.sub.6 alkenylthio, C.sub.3 -C.sub.6 alkynyloxy, C.sub.3 -C.sub.6 haloalkynyloxy, C.sub.1 -C.sub.8 alkyl which is substituted by halogen, cyano and/or C.sub.1 -C.sub.4 alkoxy, or are unsubstituted C.sub.1 -C.sub.8 alkoxy or halogen-substituted C.sub.1 -C.sub.8 alkoxy, the alkyl moiety of which may be interrupted by one or more single oxygen atoms, or are the Q--(E).sub.n --(X).sub.m group, in which n is 0 or 1, m is 0 or 1, Q is phenyl which is unsubstituted or substituted by halogen, nitro, C.sub.1 -C.sub.3 alkyl, CF.sub.3 and/or C.sub.1 -C.sub.3 alkoxy, or is a saturated or unsaturated heterocyclic radical containing one or more hetero atoms, E is a C.sub.1 -C.sub.3 alkylene bridge, and X is oxygen or sulfur, and R.sub.6 and/or one of the radicals R.sub.5 or R.sub.7 can also be hydrogen.Also disclosed are methods of preparing these compounds, and agrochemical compositions which contain one such compound as active ingredient. The invention further relates to the use of the novel compounds, or compositions containing them, in agriculture and related fields.
    • 本发明公开了通式I(I)的新型N-(2-硝基苯基)-2-氨基嘧啶衍生物,其中R 1和R 2是氢,NO 2或CF 3,条件是只有R 1或R 2可以是NO 2; R 4是氢或-C(O)R'基团,其中R'是未被取代或被卤素,C 1 -C 3烷氧基或C 1 -C 3烷硫基取代的C 1 -C 4烷基; R5,R6和R7各自独立地为卤素,硝基,氰基,氰基,C1-C12烷基,C3-C8环烷基,C1-C8烷硫基,C1-C6烷基磺酰基,C1-C6烷基亚磺酰基,C3-C6链烯基,C3-C6卤代烯基,C3-C6炔基, C 6卤代炔基,C 3 -C 6烯氧基,C 3 -C 6卤代烯氧基,C 3 -C 6烯基硫基,C 3 -C 6炔氧基,C 3 -C 6卤代炔氧基,被卤素,氰基和/或C 1 -C 4烷氧基取代的C 1 -C 8烷基,或未取代的C 1 -C 8烷氧基或卤素取代的C 1 C 1-8烷氧基,其烷基部分可被一个或多个单个氧原子间隔,或是Q-(E)n-(X)m基团,其中n为0或1,m为0或1,Q 是未取代的或被卤素,硝基,C 1 -C 3烷基,CF 3和/或C 1 -C 3烷氧基取代的苯基,或是含有一个或多个杂原子的饱和或不饱和杂环基,E是C 1 -C 3亚烷基桥,X是 氧或硫,R6和/或基团R5或R7之一也可以是氢。 还公开了制备这些化合物的方法和含有一种这样的化合物作为活性成分的农药组合物。 本发明还涉及在农业和相关领域中使用含有它们的新化合物或组合物。
    • 4. 发明授权
    • N-(2-nitrophenyl)-2-aminopyrimidine derivatives, the preparation and use
thereof
    • N-(2-硝基苯基)-2-氨基嘧啶衍生物,的制备及应用
    • US4659363A
    • 1987-04-21
    • US632161
    • 1984-07-18
    • Adolf HubeleHelmut ZondlerPeter RiebliWolfgang Eckhardt
    • Adolf HubeleHelmut ZondlerPeter RiebliWolfgang Eckhardt
    • A01N43/54C07D239/42C07D239/46C07D239/47C07D239/52C07D239/56C07D401/12
    • C07D239/42A01N43/54C07D239/47C07D239/52C07D239/56C07D401/12
    • The invention discloses novel N-(2-nitrophenyl)-2-aminopyrimidine derivatives of the general formula I ##STR1## wherein R.sub.1 and R.sub.2 are each independently NO.sub.2 or CF.sub.3, with the proviso that only R.sub.1 or R.sub.2 can be NO.sub.2R.sub.3 is halogen,R.sub.4 is hydrogen or the --C(O)R' group, in which R' is C.sub.1 -C.sub.4 alkyl which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkylthio,R.sub.5, R.sub.6 and R.sub.7 are each independently hydrogen, halogen, nitro, cyano, thiocyano, C.sub.1 -C.sub.12 alkyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.1 -C.sub.8 alkylthio, C.sub.1 -C.sub.6 alkylsulfonyl, C.sub.1 -C.sub.6 alkylsulfoxyl, C.sub.3 -C.sub.6 alkenyl, C.sub.3 -C.sub.6 haloalkenyl, C.sub.3 -C.sub.6 alkynyl, C.sub.3 -C.sub.6 haloalkynyl, C.sub.3 -C.sub.6 alkenyloxy, C.sub.3 -C.sub.6 -haloalkenyloxy, C.sub.3 -C.sub.6 alkenylthio, C.sub.3 -C.sub.6 alkynyloxy, C.sub.3 -C.sub.6 haloalkynyloxy, C.sub.1 -C.sub.8 alkyl which is substituted by halogen, cyano and/or C.sub.1 -C.sub.4 alkoxy, unsubstituted C.sub.1 -C.sub.8 alkoxy or halogen-substituted C.sub.1 -C.sub.8 alkoxy, the alkyl moiety of which may be interrupted by one or more single oxygen atoms; or are the Q--(E).sub.n --(X).sub.m -group, in which n is 0 or 1, m is 0 or 1, Q is phenyl which is unsubstituted or substituted by halogen, nitro, C.sub.1 -C.sub.3 alkyl, CF.sub.3 and/or C.sub.1 -C.sub.3 alkoxy, or is a saturated or unsaturated heterocyclic radical containing one or more hetero atoms, E is a C.sub.1 -C.sub.3 alkylene bridge, and X is oxygen or sulfur.Also disclosed are methods of preparing these compounds, and also agrochemical compositions which contain one such compound as active ingredient. The invention further relates to the use of the novel compounds, or, compositions containing them, in agriculture and related fields.
    • 本发明公开了通式I(I)的新型N-(2-硝基苯基)-2-氨基嘧啶衍生物,其中R 1和R 2各自独立地为NO 2或CF 3,条件是仅R 1或R 2可为NO 2 R 3 C 1 -C 3烷氧基或C 1 -C 3烷硫基,R 5,R 6和R 7各自独立地为氢,R 4为氢或-C(O)R'基团,其中R'为未被取代或被卤素取代的C 1 -C 4烷基, 卤素,硝基,氰基,硫氰基,C 1 -C 12烷基,C 3 -C 8环烷基,C 1 -C 8烷硫基,C 1 -C 6烷基磺酰基,C 1 -C 6烷基亚磺酰基,C 3 -C 6烯基,C 3 -C 6卤代烯基,C 3 -C 6炔基,C 3 -C 6卤代炔基,C 3 -C 6烯氧基, C 6-卤代链烯氧基,C 3 -C 6烯基硫基,C 3 -C 6炔氧基,C 3 -C 6卤代炔氧基,被卤素,氰基和/或C 1 -C 4烷氧基取代的C 1 -C 8烷基,未取代的C 1 -C 8烷氧基或卤素取代的C 1 -C 8烷氧基, 其可被一个或多个单个氧原子中断; 或者是Q-(E)n-(X)m-基,其中n为0或1,m为0或1,Q为未被取代或被卤素,硝基,C 1 -C 3烷基,CF 3和 或C1-C3烷氧基,或是含有一个或多个杂原子的饱和或不饱和杂环基,E是C1-C3亚烷基桥,X是氧或硫。 还公开了制备这些化合物的方法,以及含有一种这样的化合物作为活性成分的农药组合物。 本发明还涉及在农业和相关领域中新颖化合物或含有它们的组合物的用途。
    • 8. 发明授权
    • Fungicidal 3-[N-(pyrazol-1-yl-acetyl)-N-(substituted
phenyl)]-amino-tetrahydro-2-furanones
    • 杀真菌剂3- [N-(吡唑-1-基 - 乙酰基)-N-(取代的苯基)] - 氨基 - 四氢-2-呋喃酮
    • US4296118A
    • 1981-10-20
    • US180266
    • 1980-08-22
    • Walter KunzWolfgang EckhardtAdolf Hubele
    • Walter KunzWolfgang EckhardtAdolf Hubele
    • A01N43/08A01N43/16A01N43/56A01N43/653C07D307/33C07D307/68C07D405/12C07D521/00
    • C07D307/33A01N43/08A01N43/56A01N43/653C07D231/12C07D233/56C07D249/08C07D307/68
    • N-Acylated N-phenyl-aminotetrahydro-2-furanones of tthe formula ##STR1## wherein R represents C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,R.sub.1 represents C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,R.sub.2 represents hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,R.sub.3 represents hydrogen or methyl, with the total number of C atoms of the substituents R, R.sub.1, R.sub.2 and R.sub.3 in the phenyl ring not exceeding the number 8,R.sub.4 represents hydrogen or methyl, whileR.sub.5 represents one of the following groups: an alkylthioalkyl or alkoxyalkyl group having 2 to 5 carbon atoms or an alkoxyalkoxymethyl group having a maximum of 6 carbon atoms, a 2-furanyl or 2-tetrahydrofuranyl group optionally substituted by halogen, a 1,2,4-triazolymethyl group, a 1,2-pyrazolylmethyl group, or a group -CH.sub.2 -OR.sub.6 in which R.sub.6 represents a 5- or 6-membered heterocycle having oxygen as the hetero atom are valuable fungicidal active substances. They can be used as fungicidal compositions, particularly for combating phytopathogenic fungi, e.g. against downy mildew on potatoes, tomatoes, grape vines and sugar beet and other plants. The novel compounds have a systemic action.
    • 其中R代表C1-C4烷基,C1-C4-烷氧基或卤素,R1代表C1-C3-烷基,C1-C4-烷氧基或卤素的N-酰基化N-苯基 - 氨基四氢-2-呋喃酮 ,R 2表示氢,C 1 -C 3 - 烷基,C 1 -C 4 - 烷氧基或卤素,R 3表示氢或甲基,苯基环中取代基R,R 1,R 2和R 3的C原子总数不超过 8,R 4表示氢或甲基,而R 5表示以下基团之一:烷基硫代烷基或碳原子数2〜5的烷氧基烷基或最多6个碳原子的烷氧基烷氧基甲基,2-呋喃基或2-四氢呋喃基 被卤素取代,1,2,4-三唑甲基,1,2-吡唑基甲基或基团-CH2-OR6,其中R6表示具有氧作为杂原子的5-或6-元杂环是有价值的杀真菌剂 活性物质。 它们可以用作杀真菌组合物,特别是用于防治植物病原真菌,例如, 反对马铃薯,西红柿,葡萄藤和甜菜等植物的霜霉病。 新化合物具有全身作用。