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1. 发明申请

WO2013066724A1 APPARATUS AND METHOD PERTAINING TO MOVEMENT COMPENSATION DURING RADIATION TREATMENT 审中-公开
标题翻译：放射治疗期间运动补偿的装置和方法
公开(公告)号：WO2013066724A1
公开(公告)日：2013-05-10
申请号：PCT/US2012/061930
申请日：2012-10-25
申请人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG , VARIAN MEDICAL SYSTEMS, INC.
发明人： SILJAMAKI, Sami , NORD, Janne , SVATOS, Michelle Marie , ZANKOWSKI, Corey E. , MANSFIELD, Stanley
IPC分类号： A61N5/00 , A61N5/10 , A61B6/08
CPC分类号： A61N5/1045 , A61N5/1037 , A61N5/1067 , A61N5/107 , A61N2005/105
摘要： A control circuit controls real-time administration of a radiation-treatment plan that administers a therapeutic radiation dose to a patient. This includes compensating for a first movement as regards the application setting using a first treatment-administration modality and responding to detection of a second movement by using a second treatment-administration modality that is different from the first treatment-administration modality.
摘要翻译：控制电路控制对患者施加治疗辐射剂量的放射治疗计划的实时管理。这包括通过使用与第一治疗管理模式不同的第二治疗施用模式来补偿关于使用第一治疗管理模式的应用设置的第一动作并且响应于第二运动的检测。

2. 发明申请

WO2018153962A1 RADIATION TREATMENT PLANNING AND DELIVERY USING COLLISION FREE REGIONS 审中-公开
公开(公告)号：WO2018153962A1
公开(公告)日：2018-08-30
申请号：PCT/EP2018/054350
申请日：2018-02-22
申请人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG , VARIAN MEDICAL SYSTEMS INC
发明人： NORD, Janne , PYYRY, Joakim , HARRINGTON, Adam , HERRIES, Sean , SCHUMM, Joseph , FILIBERTI, Reto , JYRKKALA, Kari , SPIESSENS, Sylvie , MEIER, Roland , GASSER, Dominique
IPC分类号： A61N5/10
摘要： Collision free regions (610, 620, and 630) are predetermined for one or more class solutions. Each class solution has defined limits for allowed field geometry variations. Collision free regions in planning can be defined as a set of allowed isocenter positions relative to a fixation device. The collision free regions may be visualized by a user to plan for field geometry and isocenter position tradeoffs. Collision free regions in delivery can be defined as a set of allowed couch support coordinates. The treatment fields in a radiation treatment plan can be checked against the collision free regions in delivery to determine whether they will pose any collision risks.

3. 发明申请

WO2017044562A1 KNOWLEDGE-BASED SPATIAL DOSE METRICS AND METHODS TO GENERATE BEAM ORIENTATIONS IN RADIOTHERAPY 审中-公开
标题翻译：基于知识的空间剂量度量和放射治疗中生成光束方位的方法
公开(公告)号：WO2017044562A1
公开(公告)日：2017-03-16
申请号：PCT/US2016/050674
申请日：2016-09-08
申请人： VARIAN MEDICAL SYSTEMS, INC. , VARIAN MEDICAL SYSTEMS INTERNATIONAL AG.
发明人： ZANKOWSKI, Corey , NORD, Janne , MARCOS, Maria Isabel, Cordero , HARTMAN, Joona , PELTOLA, Jarkko , KUUSELA, Esa
IPC分类号： A61N5/10
CPC分类号： A61N5/1031
摘要： A system for estimating a dose from a radiation therapy plan includes a memory that stores machine- readable instructions and a processor communicatively coupled to the memory, the processor operable to execute the instructions to subdivide a representation of a volume of interest into voxels. The processor also determines distances between a planned radiation field origin and each respective voxel. The processor further computes geometry-based expected (GED) metrics based on the distances, a plan parameter, and a field strength parameter. The processor sums the metrics to yield an estimated dose received by the volume of interest from the planned radiation field.
摘要翻译：用于从放射治疗计划估计剂量的系统包括存储机器可读指令的存储器和通信地耦合到存储器的处理器，所述处理器可操作以执行指令以将兴趣体积的表示细分为体素。处理器还确定计划辐射场原点与每个相应体素之间的距离。处理器还基于距离，计划参数和场强参数来计算基于几何的预期（GED）度量。处理器对指标进行总和，以产生由计划辐射场感兴趣的体积所接收的估计剂量。

4. 发明申请

WO2013180969A1 APPARATUS AND METHOD PERTAINING TO OPTIMIZING A RADIATION-TREATMENT PLAN USING HISTORICAL INFORMATION 审中-公开
标题翻译：使用历史信息优化放射治疗计划的装置和方法
公开(公告)号：WO2013180969A1
公开(公告)日：2013-12-05
申请号：PCT/US2013/041400
申请日：2013-05-16
申请人： VARIAN MEDICAL SYSTEMS, INC. , VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
发明人： ZANKOWSKI, Corey E. , NORD, Janne , PELTOLA, Jarkko , KUUSELA, Esa
IPC分类号： G06Q50/22 , A61N5/00
CPC分类号： A61N5/1031 , A61N5/1038 , A61N2005/1041 , G06F19/00
摘要： A control circuit operably couples to a memory having historical information stored therein. This historical information comprises information regarding delivered radiation doses to non-targeted patient volumes for a plurality of different volume presentations. The control circuit iteratively optimizes a radiation-treatment plan for a specific plan using that historical information. The aforementioned historical information can comprise delivered-dose metrics as correspond to different relative distances within given patients. The control circuit can employ such information to determine, for example, an estimated dosage (including, if desired, a corresponding range of estimated dosages) for at least one volume within the specific patient at a specific distance from a specific point of reference. The control circuit can compare such historical information against radiation-treatment plan optimization results to qualitatively assess the radiation-treatment plan optimization results.
摘要翻译：控制电路可操作地耦合到存储有历史信息的存储器。该历史信息包括关于针对多个不同体积呈现的非目标患者体积的递送辐射剂量的信息。控制电路使用该历史信息对特定计划的辐射处理计划进行迭代优化。上述历史信息可以包括对应于给定患者内的不同相对距离的递送剂量度量。控制电路可以使用这样的信息来确定特定患者中距离特定参考点特定距离的至少一个体积的估计剂量（包括如果需要，相应的估计剂量范围）。控制电路可以将这些历史信息与放射治疗计划优化结果进行比较，对辐射治疗计划优化结果进行定性评估。

5. 发明授权

EP3434328B1 APPARATUS TO FACILITATE THE ADMINISTRATION OF A KNOWLEDGE-BASED RADIATION TREATMENT PLAN 有权转让
公开(公告)号：EP3434328B1
公开(公告)日：2020-06-03
申请号：EP18184632.0
申请日：2018-07-20
申请人： Varian Medical Systems International AG , Varian Medical Systems Inc
发明人： NORD, Janne , HARTMAN, Joona , KUUSELA, Esa , ZANKOWSKI, Corey
IPC分类号： A61N5/10

6. 发明授权

EP2773425B1 APPARATUS PERTAINING TO MOVEMENT COMPENSATION DURING RADIATION TREATMENT 有权
公开(公告)号：EP2773425B1
公开(公告)日：2018-12-05
申请号：EP12844830.5
申请日：2012-10-25
申请人： Varian Medical Systems International AG , Varian Medical Systems, Inc.
发明人： SILJAMAKI, Sami , NORD, Janne , SVATOS, Michelle Marie , ZANKOWSKI, Corey E. , MANSFIELD, Stanley
IPC分类号： A61N5/00 , A61N5/10 , A61B6/08
CPC分类号： A61N5/1045 , A61N5/1037 , A61N5/1067 , A61N5/107 , A61N2005/105
摘要： A control circuit controls real-time administration of a radiation-treatment plan that administers a therapeutic radiation dose to a patient. This includes compensating for a first movement as regards the application setting using a first treatment-administration modality and responding to detection of a second movement by using a second treatment-administration modality that is different from the first treatment-administration modality.

7. 发明公开

EP2773425A1 APPARATUS AND METHOD PERTAINING TO MOVEMENT COMPENSATION DURING RADIATION TREATMENT 审中-公开
标题翻译：设备技术运动补偿过程中放射治疗
公开(公告)号：EP2773425A1
公开(公告)日：2014-09-10
申请号：EP12844830.5
申请日：2012-10-25
申请人： Varian Medical Systems, International AG , Varian Medical Systems Inc.
发明人： SILJAMAKI, Sami , NORD, Janne , SVATOS, Michelle Marie , ZANKOWSKI, Corey E. , MANSFIELD, Stanley
IPC分类号： A61N5/00 , A61N5/10 , A61B6/08
CPC分类号： A61N5/1045 , A61N5/1037 , A61N5/1067 , A61N5/107 , A61N2005/105
摘要： A control circuit controls real-time administration of a radiation-treatment plan that administers a therapeutic radiation dose to a patient. This includes compensating for a first movement as regards the application setting using a first treatment-administration modality and responding to detection of a second movement by using a second treatment-administration modality that is different from the first treatment-administration modality.

8. 发明公开

EP3585482A1 RADIATION TREATMENT PLANNING AND DELIVERY USING COLLISION FREE REGIONS 有权转让
公开(公告)号：EP3585482A1
公开(公告)日：2020-01-01
申请号：EP18714697.2
申请日：2018-02-22
申请人： Varian Medical Systems International AG , Varian Medical Systems Inc
发明人： NORD, Janne , PYYRY, Joakim , HARRINGTON, Adam , HERRIES, Sean , SCHUMM, Joseph , FILIBERTI, Reto , JYRKKALA, Kari , SPIESSENS, Sylvie , MEIER, Roland , GASSER, Dominique
IPC分类号： A61N5/10

9. 发明公开

EP3434328A1 APPARATUS TO FACILITATE THE ADMINISTRATION OF A KNOWLEDGE-BASED RADIATION TREATMENT PLAN 有权转让
公开(公告)号：EP3434328A1
公开(公告)日：2019-01-30
申请号：EP18184632.0
申请日：2018-07-20
申请人： Varian Medical Systems International AG , Varian Medical Systems Inc
发明人： NORD, Janne , HARTMAN, Joona , KUUSELA, Esa , ZANKOWSKI, Corey
IPC分类号： A61N5/10
摘要： A control circuit accesses information regarding a plurality of pre-existing vetted radiation treatment plans 202 for a variety of patients and uses that information to train at least one model 201 (such as a dose volume histogram estimation model). The control circuit then uses that model to develop estimates for a radiation treatment plan for a particular patient 209. The control circuit can then use those estimates to develop a candidate radiation treatment plan 210.

10. 发明公开

EP3347093A1 KNOWLEDGE-BASED SPATIAL DOSE METRICS AND METHODS TO GENERATE BEAM ORIENTATIONS IN RADIOTHERAPY 审中-公开
公开(公告)号：EP3347093A1
公开(公告)日：2018-07-18
申请号：EP16766783.1
申请日：2016-09-08
申请人： Varian Medical Systems, Inc. , Varian Medical Systems International AG
发明人： ZANKOWSKI, Corey , NORD, Janne , MARCOS, Maria Isabel Cordero , HARTMAN, Joona , PELTOLA, Jarkko , KUUSELA, Esa
IPC分类号： A61N5/10
CPC分类号： A61N5/1031
摘要： A system for estimating a dose from a radiation therapy plan includes a memory that stores machine-readable instructions and a processor communicatively coupled to the memory, the processor operable to execute the instructions to subdivide a representation of a volume of interest into voxels. The processor also determines distances between a planned radiation field origin and each respective voxel. The processor further computes geometry-based expected (GED) metrics based on the distances, a plan parameter, and a field strength parameter. The processor sums the metrics to yield an estimated dose received by the volume of interest from the planned radiation field.

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