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    • 4. 发明申请
    • Optical interface for disposable bioreactors
    • 一次性生物反应器的光学接口
    • US20080171383A1
    • 2008-07-17
    • US11725255
    • 2007-03-17
    • Mark SelkerBenjamin BlizardTimothy JohnstonBarbara Paldus
    • Mark SelkerBenjamin BlizardTimothy JohnstonBarbara Paldus
    • C12M1/34
    • C12M23/14C12M29/00C12M41/26C12M41/32C12M41/34
    • A port assembly for use with a polymeric bioreactor bag said assembly comprising: i) a hollow port member comprised at least in part of a material suitable to be fusibly affixed to the wall surface of said bioreactor bag; ii) at least one fluorophore spot positioned on said port member; iii) conduit means for conveying excitation light from an optical source to said fluorophore, said conduit means being an assembly comprising at least one of a lens, an optic fiber, a curved parabolic collimator, a shaped reflector or a wave guide; iv) conduit means for conveying fluorescent emission light from said fluorophore to a photo-detector, said conduit means being an assembly comprising at least one of a lens, an optic fiber, a curved parabolic collimator, a shaped reflector or a wave guide.
    • 一种与聚合物生物反应器袋一起使用的端口组件,所述组件包括:i)中空端口构件,其至少部分地包括适于被柔性地固定到所述生物反应器袋的壁表面的材料; ii)位于所述端口构件上的至少一个荧光团斑点; iii)用于将来自光源的激发光传送到所述荧光团的导管装置,所述导管装置是包括透镜,光纤,弯曲抛物线准直器,成形反射器或波导中的至少一个的组件; iv)用于将来自所述荧光团的荧光发射光传送到光检测器的导管装置,所述导管装置是包括透镜,光纤,弯曲抛物线准直仪,成形反射器或波导中的至少一个的组件。
    • 8. 发明申请
    • Optical collection geometries for phase fluorimetry
    • 用于相位荧光测定的光学收集几何
    • US20080170224A1
    • 2008-07-17
    • US11724818
    • 2007-03-16
    • Mark SelkerBenjamin BlizardTimothy Johnston
    • Mark SelkerBenjamin BlizardTimothy Johnston
    • G01J3/30
    • G01N21/6428G01N2021/6441
    • Apparatus and method for the stimulation and collection of fluorescent signals, said apparatus comprising: i) a frequency modulated optical source which emits excitation light of a wavelength which will stimulate a target fluorophore to emit a fluorescent signal when illuminated by said excitation light: ii) a first optical filter interposed between said optical source and said target fluorophore, iii) a second optical filter interposed between said fluorophore and a photo-detector positioned to receive said emitted fluorescent signal, and iv) a data processor which calculates and records the phase delay between said excitation light and said fluorescent signal wherein the beam path of at least one of the excitation light and the fluorescent signal is transmitted substantially through free space.
    • 用于刺激和收集荧光信号的装置和方法,所述装置包括:i)调频光源,其发射波长的激发光,其将在被所述激发光照射时刺激目标荧光团发射荧光信号:ii) 插入在所述光源和所述目标荧光团之间的第一滤光器,iii)置于所述荧光团和位于接收所述发射的荧光信号的光检测器之间的第二滤光器,以及iv)数据处理器,其计算并记录相位延迟 在所述激发光和所述荧光信号之间,其中激发光和荧光信号中的至少一个的光束路径基本上透过自由空间传播。
    • 9. 发明申请
    • Ear Coupling Status Sensor
    • 耳耦合状态传感器
    • US20130121494A1
    • 2013-05-16
    • US13296415
    • 2011-11-15
    • Timothy Johnston
    • Timothy Johnston
    • H04R29/00
    • H04R1/1041H04R1/1008H04R3/005H04R3/007H04R29/001H04R2460/09
    • A system and method configured to determine if a user is appropriately wearing an audio device, such as a headset, is described that enables a more accurate calculation of the audio device's acoustical characteristics. Headsets, such as headphones and earbuds, include a plurality of engagement sensors configured to determine if the audio device is engaged with the user's body. Engagement sensors may comprise capacitive sensors configured to communicate their state to an engagement sensor processing circuit, which may be located in a digital signal processor. If the engagement sensor processing circuit determines that the audio device is properly engaged with the user's body, then the circuit sends a signal that engages the calculation of various audio device acoustical quality calculations that among other things may satisfy various regulatory requirements and may also lead to an improved user experience.
    • 描述了一种被配置为确定用户是否适当佩戴诸如头戴式耳机之类的音频设备的系统和方法,其能够更准确地计算音频设备的声学特性。 诸如耳机和耳塞之类的耳机包括配置成确定音频设备是否与用户身体接合的多个接合传感器。 接合传感器可以包括被配置为将其状态传送到可以位于数字信号处理器中的接合传感器处理电路的电容式传感器。 如果接合传感器处理电路确定音频设备与用户身体正确接合,则电路发送一个信号,该信号涉及各种音频设备声学质量计算的计算,其中可以满足各种规范要求,并且还可以导致 改善用户体验。