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    • 2. 发明申请
    • Ear Coupling Status Sensor
    • 耳耦合状态传感器
    • US20130121494A1
    • 2013-05-16
    • US13296415
    • 2011-11-15
    • Timothy Johnston
    • Timothy Johnston
    • H04R29/00
    • H04R1/1041H04R1/1008H04R3/005H04R3/007H04R29/001H04R2460/09
    • A system and method configured to determine if a user is appropriately wearing an audio device, such as a headset, is described that enables a more accurate calculation of the audio device's acoustical characteristics. Headsets, such as headphones and earbuds, include a plurality of engagement sensors configured to determine if the audio device is engaged with the user's body. Engagement sensors may comprise capacitive sensors configured to communicate their state to an engagement sensor processing circuit, which may be located in a digital signal processor. If the engagement sensor processing circuit determines that the audio device is properly engaged with the user's body, then the circuit sends a signal that engages the calculation of various audio device acoustical quality calculations that among other things may satisfy various regulatory requirements and may also lead to an improved user experience.
    • 描述了一种被配置为确定用户是否适当佩戴诸如头戴式耳机之类的音频设备的系统和方法,其能够更准确地计算音频设备的声学特性。 诸如耳机和耳塞之类的耳机包括配置成确定音频设备是否与用户身体接合的多个接合传感器。 接合传感器可以包括被配置为将其状态传送到可以位于数字信号处理器中的接合传感器处理电路的电容式传感器。 如果接合传感器处理电路确定音频设备与用户身体正确接合,则电路发送一个信号,该信号涉及各种音频设备声学质量计算的计算,其中可以满足各种规范要求,并且还可以导致 改善用户体验。
    • 6. 发明申请
    • Gas control in a reactor
    • 反应堆中的气体控制
    • US20050271560A1
    • 2005-12-08
    • US11147415
    • 2005-06-07
    • Seth RodgersA. RussoTimothy JohnstonSean LeBlanc
    • Seth RodgersA. RussoTimothy JohnstonSean LeBlanc
    • B01J19/00B01L3/00C12M20060101
    • B01J19/0093B01J2219/00837B01J2219/00862B01J2219/00869B01J2219/00907B01J2219/00952B01J2219/00963B01J2219/0097B01L3/5025B01L3/502715B01L3/502746B01L2200/027B01L2200/0668B01L2200/0684B01L2300/0816B01L2300/0825B01L2300/0877B01L2300/0887B01L2300/10B01L2400/0457B01L2400/0688B01L2400/086
    • Chemical, biological, and/or biochemical reaction systems, including chips or reactors, may be configured so as to restrain immiscible materials such as gas bubbles from interfering with the determination of environmental factors associated with the chip according to one aspect of the invention. In another aspect, a chip or other reaction system may be configured to maintain a gas headspace in the chip or other reaction system. In certain embodiments, impediments such as physical barriers may be used to contain gas bubbles within a gas containing region, or otherwise away from a detection region. In other embodiments, surface tension properties may be used to control the location of gas bubbles. The chip or other reaction systems may include reaction site containers that can be very small, for example, having a volume of less than about 2 ml. In certain embodiments, chips or other reaction systems of the invention include one or more reaction sites, which, in some cases, may be defined by reaction site containers. According to another aspect of the invention, a reaction site container may be shaped to limit the formation of gas bubbles during the filling of the reaction site container with liquid by providing reaction site container shapes that do not include sharp angles or abrupt changes in reaction site container width.
    • 包括芯片或反应器的化学,生物和/或生物化学反应系统可以被配置为根据本发明的一个方面来抑制诸如气泡的不混溶材料干扰与芯片相关的环境因素的确定。 在另一方面,芯片或其它反应系统可以被配置为在芯片或其他反应系统中保持气体顶部空间。 在某些实施方案中,阻挡物例如物理屏障可以用于在含气体区域内或以其他方式远离检测区域容纳气泡。 在其它实施例中,可以使用表面张力特性来控制气泡的位置。 芯片或其他反应系统可以包括可以非常小的反应位点容器,例如具有小于约2ml的体积。 在某些实施方案中,本发明的芯片或其它反应体系包括一个或多个反应位点,其在一些情况下可由反应位点容器限定。 根据本发明的另一方面,反应部位容器可以成形为通过提供不包括尖锐角度的反应部位容器形状或反应部位的突然变化来限制在用液体填充反应部位容器期间产生气泡的形成 容器宽度。
    • 8. 发明申请
    • Optical interface for disposable bioreactors
    • 一次性生物反应器的光学接口
    • US20080171383A1
    • 2008-07-17
    • US11725255
    • 2007-03-17
    • Mark SelkerBenjamin BlizardTimothy JohnstonBarbara Paldus
    • Mark SelkerBenjamin BlizardTimothy JohnstonBarbara Paldus
    • C12M1/34
    • C12M23/14C12M29/00C12M41/26C12M41/32C12M41/34
    • A port assembly for use with a polymeric bioreactor bag said assembly comprising: i) a hollow port member comprised at least in part of a material suitable to be fusibly affixed to the wall surface of said bioreactor bag; ii) at least one fluorophore spot positioned on said port member; iii) conduit means for conveying excitation light from an optical source to said fluorophore, said conduit means being an assembly comprising at least one of a lens, an optic fiber, a curved parabolic collimator, a shaped reflector or a wave guide; iv) conduit means for conveying fluorescent emission light from said fluorophore to a photo-detector, said conduit means being an assembly comprising at least one of a lens, an optic fiber, a curved parabolic collimator, a shaped reflector or a wave guide.
    • 一种与聚合物生物反应器袋一起使用的端口组件,所述组件包括:i)中空端口构件,其至少部分地包括适于被柔性地固定到所述生物反应器袋的壁表面的材料; ii)位于所述端口构件上的至少一个荧光团斑点; iii)用于将来自光源的激发光传送到所述荧光团的导管装置,所述导管装置是包括透镜,光纤,弯曲抛物线准直器,成形反射器或波导中的至少一个的组件; iv)用于将来自所述荧光团的荧光发射光传送到光检测器的导管装置,所述导管装置是包括透镜,光纤,弯曲抛物线准直仪,成形反射器或波导中的至少一个的组件。