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1. 外观设计

USD656851S1 Pressure sensor 有权
公开(公告)号：USD656851S1
公开(公告)日：2012-04-03
申请号：US29372503
申请日：2010-11-30
申请人： Nicholas Selchow , M{dot over (a)}rk Selker , Timothy Johnston
设计人： Nicholas Selchow , M{dot over (a)}rk Selker , Timothy Johnston

2. 发明授权

US09267100B2 Composite sensor assemblies for single use bioreactors 有权
标题翻译：用于单次生物反应器的复合传感器组件
公开(公告)号：US09267100B2
公开(公告)日：2016-02-23
申请号：US13385100
申请日：2012-02-02
申请人： Mark Selker , Timothy Johnston , Barbara Paldus
发明人： Mark Selker , Timothy Johnston , Barbara Paldus
IPC分类号： C12M1/00 , G01N21/359 , G01N21/552 , G01N21/65 , G01N21/85
CPC分类号： C12M27/14 , C12M23/00 , C12M29/00 , C12M29/06 , G01N21/359 , G01N21/552 , G01N21/65 , G01N21/8507
摘要： A composite sensor assembly for monitoring bio-processes which is suitable for use with a polymeric bioprocess vessel or with downstream equipment, and comprises: i) a port comprising a high surface tension thermoplastic having a hollow tubular portion and a base plate portion, the base plate portion being fusibly sealable to the bioreactor vessel at a hole in the wall thereof; ii) a generally opaque polymeric monitoring sensor assembly including electrical, and/or optical measurement components. The sensor assembly fits inside the bore of the hollow tubular portion of the port, and is adhesively retained therein.
摘要翻译：一种用于监测适用于聚合物生物过程容器或与下游设备的生物过程的复合传感器组件，包括：i）包含具有中空管状部分和底板部分的高表面张力热塑性塑料的端口，板部分在其壁的孔处易于密封到生物反应器容器; ii）包括电和/或光学测量部件的通常不透明的聚合物监测传感器组件。传感器组件装配在端口的中空管状部分的孔内，并且粘合地保持在其中。

3. 发明申请

US20080171383A1 Optical interface for disposable bioreactors 有权
标题翻译：一次性生物反应器的光学接口
公开(公告)号：US20080171383A1
公开(公告)日：2008-07-17
申请号：US11725255
申请日：2007-03-17
申请人： Mark Selker , Benjamin Blizard , Timothy Johnston , Barbara Paldus
发明人： Mark Selker , Benjamin Blizard , Timothy Johnston , Barbara Paldus
IPC分类号： C12M1/34
CPC分类号： C12M23/14 , C12M29/00 , C12M41/26 , C12M41/32 , C12M41/34
摘要： A port assembly for use with a polymeric bioreactor bag said assembly comprising: i) a hollow port member comprised at least in part of a material suitable to be fusibly affixed to the wall surface of said bioreactor bag; ii) at least one fluorophore spot positioned on said port member; iii) conduit means for conveying excitation light from an optical source to said fluorophore, said conduit means being an assembly comprising at least one of a lens, an optic fiber, a curved parabolic collimator, a shaped reflector or a wave guide; iv) conduit means for conveying fluorescent emission light from said fluorophore to a photo-detector, said conduit means being an assembly comprising at least one of a lens, an optic fiber, a curved parabolic collimator, a shaped reflector or a wave guide.
摘要翻译：一种与聚合物生物反应器袋一起使用的端口组件，所述组件包括：i）中空端口构件，其至少部分地包括适于被柔性地固定到所述生物反应器袋的壁表面的材料; ii）位于所述端口构件上的至少一个荧光团斑点; iii）用于将来自光源的激发光传送到所述荧光团的导管装置，所述导管装置是包括透镜，光纤，弯曲抛物线准直器，成形反射器或波导中的至少一个的组件; iv）用于将来自所述荧光团的荧光发射光传送到光检测器的导管装置，所述导管装置是包括透镜，光纤，弯曲抛物线准直仪，成形反射器或波导中的至少一个的组件。

4. 发明授权

US10227555B2 Composite sensor assemblies for single use bioreactors 有权
公开(公告)号：US10227555B2
公开(公告)日：2019-03-12
申请号：US13134157
申请日：2011-05-31
申请人： Mark Selker , Barbara Paldus , Timothy Johnston
发明人： Mark Selker , Barbara Paldus , Timothy Johnston
IPC分类号： C12M1/34 , C12M1/00 , C12M3/06 , G01N21/359 , G01N21/552 , G01N21/65 , G01N21/78 , G01N21/80 , G01N21/77
摘要： A composite sensor assembly for monitoring bio-processes which is suitable for use with a polymeric bioprocess vessel or with downstream equipment, and comprises: i) a port comprising a high surface tension thermoplastic having a hollow tubular portion and a base plate portion, the base plate being fusibly sealable to the bioreactor vessel at a hole in the wall thereof; ii) a generally opaque polymeric monitoring sensor assembly including electrical, and/or optical measurement components. The sensor assembly fits inside the bore of the hollow tubular portion of the port, and is adhesively retained therein.

5. 发明申请

US20120244608A1 Composite sensor assemblies for single use bioreactors 审中-公开
标题翻译：用于单次生物反应器的复合传感器组件
公开(公告)号：US20120244608A1
公开(公告)日：2012-09-27
申请号：US13134157
申请日：2011-05-31
申请人： Mark Selker , Barbara Paldus , Timothy Johnston
发明人： Mark Selker , Barbara Paldus , Timothy Johnston
IPC分类号： C12M1/34 , B32B38/16 , C12M1/00
CPC分类号： C12M41/00 , C12M23/14 , C12M23/28 , C12M27/16 , G01N21/359 , G01N21/552 , G01N21/65 , G01N21/783 , G01N21/80 , G01N2021/7786
摘要： A composite sensor assembly for monitoring bio-processes which is suitable for use with a polymeric bioprocess vessel or with downstream equipment, and comprises: i) a port comprising a high surface tension thermoplastic having a hollow tubular portion and a base plate portion, the base plate being fusibly sealable to the bioreactor vessel at a hole in the wall thereof; ii) a generally opaque polymeric monitoring sensor assembly including electrical, and/or optical measurement components. The sensor assembly fits inside the bore of the hollow tubular portion of the port, and is adhesively retained therein.
摘要翻译：一种用于监测适用于聚合物生物过程容器或与下游设备的生物过程的复合传感器组件，包括：i）包含具有中空管状部分和底板部分的高表面张力热塑性塑料的端口，板在其壁的孔处易于密封到生物反应器容器; ii）包括电和/或光学测量部件的通常不透明的聚合物监测传感器组件。传感器组件装配在端口的中空管状部分的孔内，并且粘合地保持在其中。

6. 发明申请

US20080170224A1 Optical collection geometries for phase fluorimetry 有权
标题翻译：用于相位荧光测定的光学收集几何
公开(公告)号：US20080170224A1
公开(公告)日：2008-07-17
申请号：US11724818
申请日：2007-03-16
申请人： Mark Selker , Benjamin Blizard , Timothy Johnston
发明人： Mark Selker , Benjamin Blizard , Timothy Johnston
IPC分类号： G01J3/30
CPC分类号： G01N21/6428 , G01N2021/6441
摘要： Apparatus and method for the stimulation and collection of fluorescent signals, said apparatus comprising: i) a frequency modulated optical source which emits excitation light of a wavelength which will stimulate a target fluorophore to emit a fluorescent signal when illuminated by said excitation light: ii) a first optical filter interposed between said optical source and said target fluorophore, iii) a second optical filter interposed between said fluorophore and a photo-detector positioned to receive said emitted fluorescent signal, and iv) a data processor which calculates and records the phase delay between said excitation light and said fluorescent signal wherein the beam path of at least one of the excitation light and the fluorescent signal is transmitted substantially through free space.
摘要翻译：用于刺激和收集荧光信号的装置和方法，所述装置包括：i）调频光源，其发射波长的激发光，其将在被所述激发光照射时刺激目标荧光团发射荧光信号：ii）插入在所述光源和所述目标荧光团之间的第一滤光器，iii）置于所述荧光团和位于接收所述发射的荧光信号的光检测器之间的第二滤光器，以及iv）数据处理器，其计算并记录相位延迟在所述激发光和所述荧光信号之间，其中激发光和荧光信号中的至少一个的光束路径基本上透过自由空间传播。

7. 发明授权

US08499886B2 Expander ear tip 有权
标题翻译：扩口耳
公开(公告)号：US08499886B2
公开(公告)日：2013-08-06
申请号：US13273553
申请日：2011-10-14
申请人： Timothy Johnston , Jacob Meyberg , Eric Bradford
发明人： Timothy Johnston , Jacob Meyberg , Eric Bradford
IPC分类号： H04R25/02 , H04R25/00
CPC分类号： H04R1/105 , H04R1/1016 , H04R5/0335
摘要： Methods and apparatuses for wearing audio products are disclosed. In one example, an apparatus for delivering sound to an ear includes a flexible material shaped to fit within an outer ear. The apparatus includes a movable member in contact with an inner surface of the flexible material, the flexible material configured to expand or retract responsive to movement of the member.
摘要翻译：公开了用于佩戴音频产品的方法和装置。在一个示例中，用于将声音传送到耳朵的装置包括成形为适合于外耳内的柔性材料。该装置包括与柔性材料的内表面接触的可移动部件，柔性材料构造成响应于构件的移动而伸展或缩回。

8. 发明申请

US20130121494A1 Ear Coupling Status Sensor 审中-公开
标题翻译：耳耦合状态传感器
公开(公告)号：US20130121494A1
公开(公告)日：2013-05-16
申请号：US13296415
申请日：2011-11-15
申请人： Timothy Johnston
发明人： Timothy Johnston
IPC分类号： H04R29/00
CPC分类号： H04R1/1041 , H04R1/1008 , H04R3/005 , H04R3/007 , H04R29/001 , H04R2460/09
摘要： A system and method configured to determine if a user is appropriately wearing an audio device, such as a headset, is described that enables a more accurate calculation of the audio device's acoustical characteristics. Headsets, such as headphones and earbuds, include a plurality of engagement sensors configured to determine if the audio device is engaged with the user's body. Engagement sensors may comprise capacitive sensors configured to communicate their state to an engagement sensor processing circuit, which may be located in a digital signal processor. If the engagement sensor processing circuit determines that the audio device is properly engaged with the user's body, then the circuit sends a signal that engages the calculation of various audio device acoustical quality calculations that among other things may satisfy various regulatory requirements and may also lead to an improved user experience.
摘要翻译：描述了一种被配置为确定用户是否适当佩戴诸如头戴式耳机之类的音频设备的系统和方法，其能够更准确地计算音频设备的声学特性。诸如耳机和耳塞之类的耳机包括配置成确定音频设备是否与用户身体接合的多个接合传感器。接合传感器可以包括被配置为将其状态传送到可以位于数字信号处理器中的接合传感器处理电路的电容式传感器。如果接合传感器处理电路确定音频设备与用户身体正确接合，则电路发送一个信号，该信号涉及各种音频设备声学质量计算的计算，其中可以满足各种规范要求，并且还可以导致改善用户体验。

9. 发明申请

US20130092470A1 Expander Ear Tip 有权
标题翻译：扩张耳提示
公开(公告)号：US20130092470A1
公开(公告)日：2013-04-18
申请号：US13273553
申请日：2011-10-14
申请人： Timothy Johnston , Jacob Meyberg , Eric Bradford
发明人： Timothy Johnston , Jacob Meyberg , Eric Bradford
IPC分类号： H04R25/02
CPC分类号： H04R1/105 , H04R1/1016 , H04R5/0335
摘要： Methods and apparatuses for wearing audio products are disclosed. In one example, an apparatus for delivering sound to an ear includes a flexible material shaped to fit within an outer ear. The apparatus includes a movable member in contact with an inner surface of the flexible material, the flexible material configured to expand or retract responsive to movement of the member.
摘要翻译：公开了用于佩戴音频产品的方法和装置。在一个示例中，用于将声音传送到耳朵的装置包括成形为适合于外耳内的柔性材料。该装置包括与柔性材料的内表面接触的可移动部件，柔性材料构造成响应于构件的移动而伸展或缩回。

10. 发明申请

US20120244609A1 Composite sensor assemblies for single use bioreactors 有权
标题翻译：用于单次生物反应器的复合传感器组件
公开(公告)号：US20120244609A1
公开(公告)日：2012-09-27
申请号：US13385100
申请日：2012-02-02
申请人： Mark Selker , Barbara Paldus , Timothy Johnston
发明人： Mark Selker , Barbara Paldus , Timothy Johnston
IPC分类号： C12M1/34 , C12M1/02 , B32B38/00 , C12M1/08
CPC分类号： C12M27/14 , C12M23/00 , C12M29/00 , C12M29/06 , G01N21/359 , G01N21/552 , G01N21/65 , G01N21/8507
摘要： A composite sensor assembly for monitoring bio-processes which is suitable for use with a polymeric bioprocess vessel or with downstream equipment, and comprises: i) a port comprising a high surface tension thermoplastic having a hollow tubular portion and a base plate portion, the base plate portion being fusibly sealable to the bioreactor vessel at a hole in the wall thereof; ii) a generally opaque polymeric monitoring sensor assembly including electrical, and/or optical measurement components. The sensor assembly fits inside the bore of the hollow tubular portion of the port, and is adhesively retained therein.
摘要翻译：一种用于监测适用于聚合物生物过程容器或与下游设备的生物过程的复合传感器组件，包括：i）包含具有中空管状部分和底板部分的高表面张力热塑性塑料的端口，板部分在其壁的孔处易于密封到生物反应器容器; ii）包括电和/或光学测量部件的通常不透明的聚合物监测传感器组件。传感器组件装配在端口的中空管状部分的孔内，并且粘合地保持在其中。

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